Abstract:
:Multi-drug-resistant gram-negative rods (MRGN) are associated with increased morbidity and mortality. Little is known about the epidemiology of this group of pathogens in endemic situations. The aim of this study was to determine the epidemiology of MRGN in our facility during a 3-year period. Prospective surveillance of any patient colonized or infected with a MRGN during hospital stay from 2002 to 2004 was performed. Patients proven to harbour extended beta-lactamase (ESBL)-producing bacteria as well as cystic fibrosis (CF) patients were excluded. After culture of MRGN, patients were considered positive until three consecutive samples from all previously affected locations had been tested negative. Five hundred and three case-patients were enrolled accounting for 8081 isolation days and an incidence of 0.43 per 1000 patient days with an average length of stay of 37.5 days (average duration of isolation: 22.6 days). Sixty-six percent of case-patients were known to be positive at the time of admission. Fifty-one percent of MRGN were acquired within the hospital. The most frequently detected species was Pseudomonas aeruginosa. There were 108 case-patients with pan-resistant pathogens. Eight of 169 (4.7%) screened contact patients were found to be MRGN positive. In our hospital cross-transmission of MRGN seems to occur less frequently than cross-transmission of MRSA (9.0%) or ESBL (11.1%). To prevent nosocomial transmission it is recommended to isolate patients colonized or infected with MRGN in our hospital in single rooms. Because there are many immunocompromised patients in our facility we will continue our current infection control management until more data concerning MRGN are available.
journal_name
Int J Hyg Environ Healthauthors
Vonberg RP,Wolter A,Chaberny IF,Kola A,Ziesing S,Suerbaum S,Gastmeier Pdoi
10.1016/j.ijheh.2007.08.008subject
Has Abstractpub_date
2008-07-01 00:00:00pages
251-7issue
3-4eissn
1438-4639issn
1618-131Xpii
S1438-4639(07)00132-0journal_volume
211pub_type
杂志文章abstract::Phenols and parabens are used in a multitude of consumer products resulting in ubiquitous human exposure. Animal and in vitro studies suggest that exposure to these compounds may be related to a number of adverse health outcomes, as well as potential mediators such as oxidative stress and inflammation. We examined uri...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2014.11.001
更新日期:2015-03-01 00:00:00
abstract::Imidacloprid is a neonicotinoid insecticide commonly injected through agricultural drip irrigation systems to reduce the population of vine mealybugs (P. ficus) in grape farms. There is a growing concern of potential human health effects of imidacloprid, however, there is limited information on the exposure to imidacl...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2020.113625
更新日期:2020-09-17 00:00:00
abstract::Prenatal exposure to polybrominated diphenyl ethers (PBDEs) have been reported to impair executive function in children, but little is known whether childhood PBDE exposures play a role. Using the Health Outcomes and Measures of the Environment (HOME) Study, a prospective birth cohort in the greater Cincinnati area, w...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.10.006
更新日期:2018-01-01 00:00:00
abstract::This manuscript presents highlights of recent studies and perspectives from the French human biomonitoring (HBM) programme. Until recently, HBM studies focused on specific populations or pollutants to gain a better understanding of exposure to environmental chemicals, to help regulators reduce environmental exposure a...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2011.08.008
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Despite increasing concerns about the health effects of climate change, the extent to which workers are affected by hot weather is not well documented. This study aims to investigate the association between high temperatures and work-related injuries using data from a large subtropical city in China. METHOD...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2018.01.005
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Conflicting evidence concerning possible harm from mercury (Hg) in regard to offspring cognition if the woman eats fish has prompted this study to examine evidence from a British pre-birth cohort to investigate the relationship between the two. METHODS:Pregnant women (median prenatal blood mercury 1.86μg/L)...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.07.004
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND AND AIM:Epidemiological studies linking insecticide exposure to childhood neurodevelopment have been gaining global attention. Despite the rapid development of the central nervous system in early childhood, studies regarding the biological monitoring of insecticide exposure in diapered children are limited. ...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2016.10.009
更新日期:2017-03-01 00:00:00
abstract::To protect groundwater as a drinking water resource from microbiological contamination, protection zones are installed. While travelling through these zones, concentrations of potential pathogens should decline to levels that pose no risks to human health. Removal of viruses during subsurface passage is influenced by ...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2014.06.004
更新日期:2014-11-01 00:00:00
abstract::Multifactorial risk factors are responsible for many diseases. They can be broadly categorized as environmental, genetic and life style factors. Much attention has been focused on the first two categories, e.g. the identification of environmental toxicants/carcinogens and the elucidation of genetic susceptibility to d...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1078/1438-4639-00067
更新日期:2001-10-01 00:00:00
abstract::Between 1999 and 2003 all consecutive outpatients of the environmental medicine unit of the Charité hospital in Berlin were invited to participate in a study on environmentally related disorders. One hundred and sixty-nine of the patients completed a psychosocial questionnaire which comprised SCL-90-R and 14 other tes...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2006.11.006
更新日期:2007-12-01 00:00:00
abstract::This study aimed to evaluate the contamination level of the Peri Lagoon, the main freshwater reservoir of Santa Catarina Island, Southern Brazil, for human adenovirus (HAdV), hepatitis A virus (HAV), rotavirus species A (RVA), and somatic coliphages (SOMCPH). Viruses were also investigated in sediments and their sensi...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2016.07.009
更新日期:2016-10-01 00:00:00
abstract::Reference values (RV95) are statistically derived values comprising the rounded 95th percentiles within the 95% confidence interval and indicate the upper margin of background exposure to chemical substances in a population at a given time period. Based on representative national human biomonitoring data on several ur...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2018.06.001
更新日期:2018-07-01 00:00:00
abstract::The aim of this study was to characterize the mediator release in the whole blood assay induced by stimulation with an extract of the indoor mold A. versicolor. In addition, the effect of concomitant stimulation with E. coli endotoxin and A. versicolor, and the involvement of the relevant Toll-like receptors were inve...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2012.11.001
更新日期:2013-07-01 00:00:00
abstract::Mixtures of methylisothiazolinone and methylchloroisothiazolinone are used as biocides in cosmetics, cleaning agents, and water-based paint. A biomonitoring method to evaluate exposure to these compounds was developed using N-methylmalonamic acid (NMMA), the main metabolite of both, methylisothiazolinone and methylchl...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2020.113511
更新日期:2020-06-01 00:00:00
abstract::Non-carcinogenic effects in low-level (< 100 μgL(-1)) arsenic (As)-impacted populations, such as the development and progression of type-2 diabetes mellitus (T2DM), are often neglected given the primary emphasis of public health authorities on As carcinogenicity. We gathered studies reporting urinary biomarkers of As ...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章,meta分析
doi:10.1016/j.ijheh.2012.07.001
更新日期:2013-01-01 00:00:00
abstract::Many studies have found that household access to water supplies near or within the household plot can reduce the probability of diarrhea, trachoma, and other water-related diseases, and it is generally accepted that on-plot water supplies produce health benefits for households. However, the body of research literature...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章,评审
doi:10.1016/j.ijheh.2016.04.008
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Systemic absorption of phthalates and parabens has been demonstrated after dermal application of body lotion, and medical devices such as intravenous bags and tubing have been identified as a source of exposure to di(2-ethylhexyl) phthalate (DEHP). However, use of products during medical procedures such as a...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.08.003
更新日期:2017-11-01 00:00:00
abstract::This cross-sectional study examined the association between blood lead levels and neuropsychological and behavioural problems of 533 schoolgirls (6-12 years of age) who attended public schools in Riyadh, Capital of Saudi Arabia. Regression models were used to determine the best predictors of Beery VMI Saudi-based stan...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1078/1438-4639-00091
更新日期:2001-11-01 00:00:00
abstract::The epidemiological evidence that ambient exposure, including particulate matter (PM) is related to adverse health outcomes continues to mount. Inflammation and disease of the upper respiratory tract are commonly suggested as effects of ambient exposure. Therefore we studied both ambient exposure and nasal effects in ...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1078/1438-4639-00122
更新日期:2002-04-01 00:00:00
abstract::A national survey was conducted to determine polychlorinated dibenzo-p-dioxins and dibenofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (dl-PCBs) in human milk samples collected from 16 provinces in China to assess current exposure and temporal trends in China. The arithmetic mean concentration of total TE...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2016.07.013
更新日期:2016-11-01 00:00:00
abstract::The dissolution of metal-containing particles in the gastric compartment is poorly understood. The purpose of this study was to elucidate the influence of artificial gastric juice chemical composition on bioaccessibility of metals associated with ingestion-based health concerns. Dissolution rates were evaluated for we...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2009.12.006
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:In utero exposure to perfluorooctanoic acid (PFOA) has been associated with decreases in birth weight. We aimed to estimate the proportion of PFOA-attributable low birth weight (LBW) births and associated costs in the US from 2003 to 2014, a period during which there were industry-initiated and...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.11.004
更新日期:2018-03-01 00:00:00
abstract::Adequate access to water, sanitation, and hygiene (WaSH) in schools impacts health, educational outcomes, and gender disparities. Little multi-country research has been published on WaSH in rural schools in Sub-Saharan Africa. In this multi-national cross-sectional WaSH study, we document WaSH access, continuity, qual...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.03.015
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:The environmental justice framework states that besides environmental burdens also resources may be social unequally distributed both on the individual and on the neighbourhood level. This ecological study investigated whether neighbourhood socioeconomic position (SEP) was associated with neighbourhood publi...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2017.02.006
更新日期:2017-06-01 00:00:00
abstract::Data on inhalational and potential dermal exposures during spray application of liquid biocidal products were generated. On the one hand, model experiments with different spraying devices using fluorescent tracers were carried out to investigate the influence of parameters relevant to the exposure (e.g. spraying equip...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2005.04.006
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:Low beryllium exposure can induce pulmonary granulomatosis, so called berylliosis. For occupational health monitoring, it is more relevant to assess the internal dose of Be received by the lungs than urinary or atmospheric Be. Exhaled breath condensate (EBC) is a matrix collected non-invasively that derives f...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2015.08.003
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine if artificial neural networks (ANNs) may be useful to analyse a complex and large set of data derived from smoking welders for the purpose of finding relationships between parameters describing respiratory system efficiency and antioxidant defence. METHODS:A group of 94 ...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2006.03.004
更新日期:2006-07-01 00:00:00
abstract::Since chlorhexidine is effective against microorganisms, it is widely recommended in dentistry. However, studies have provided evidence that chlorhexidine is toxic for a variety of cell types. In order to identify potential genotoxins in different cell types, the purpose of this study was to investigate whether chlorh...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2006.09.001
更新日期:2007-03-01 00:00:00
abstract::Bacteria of the genus of Bdellovibrio are highly motile Gram-negative predators of other Gram-negative bacteria causing lysis of their prey. Here we report results of studies on the interactions of Bdellovibrio with species of Alcaligenes, Campylobacter, Erwinia, Escherichia, Helicobacter, Pseudomonas, Legionella, and...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1016/j.ijheh.2010.08.004
更新日期:2010-11-01 00:00:00
abstract::Between January and October 1994, a study of the prevalence, intensity and clinical manifestations of onchocerciasis in nine communities of Toro local government area of Bauchi State, Nigeria was undertaken using the skin-snip method. Of the 1117 inhabitants examined, 188 (16.8%) were positive for microfilariae of Onc...
journal_title:International journal of hygiene and environmental health
pub_type: 杂志文章
doi:10.1078/1438-4639-00052
更新日期:2001-07-01 00:00:00