Time to reconsider the clinical value of immunoglobulin G4 to foods?

abstract：:This paper reports on a pilot external quality assessment scheme for bone markers including serum bone alkaline phosphatase and procollagen 1-carboxy terminal propeptide together with urine deoxypyridinoline, N- and C-telopeptides. The data shows poor numerical agreement between commercial assays, between-laboratory i...

journal_title：Clinical chemistry and laboratory medicine

authors： Whitham KM,Milford-Ward A

更新日期：2000-11-01 00:00:00

abstract：:Until recently, the "human genome" programs were mainly directed towards the development of maps to identify disease genes. The genetic map comprises about 8000 highly informative second generation markers of the microsatellite type. The density of markers is now sufficient to localize a gene for a monogenic disease w...

journal_title：Clinical chemistry and laboratory medicine

authors： Weissenbach J

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:The increasing importance of anti-Müllerian hormone (AMH) for the assessment of ovarian reserve requires accurate AMH measurements. There have been conflicting results about the reliability of currently existing manual AMH assays. METHODS:Development of a high sensitive, fast and fully automated AMH assay o...

journal_title：Clinical chemistry and laboratory medicine

authors： Gassner D,Jung R

更新日期：2014-08-01 00:00:00

abstract：:We have previously reported two novel mutations in the 5'-untranslated region (UTR) of the gene for folate receptor-alpha (FOLR1). In our search for additional mutations, 92 patient samples with elevated levels of homocysteine were screened by single-strand conformation polymorphism (SSCP) between nt -425 and -782, an...

journal_title：Clinical chemistry and laboratory medicine

authors： Börjel AK,Yngve A,Sjöström M,Nilsson TK

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Increased homocysteine (Hcy) blood levels are correlated with vascular and neurological problems. AIM:The aim of the present study was to investigate erythrocyte membrane acetylcholinesterase (AChE) activity in subjects with the MTHFR C677T genotype in relation to Hcy. METHODS:Blood was obtained from 22 in...

journal_title：Clinical chemistry and laboratory medicine

authors： Tsakiris S,Schulpis KH,Papaconstantinou ED,Tsakiris T,Tjamouranis I,Giannoulia-Karantana A

更新日期：2006-01-01 00:00:00

abstract：:The detection and quantification of amyloidogenic monoclonal light chains are necessary for the diagnosis and evaluation of response to treatment in AL amyloidosis. However, the amyloid clone is often small and difficult to detect. We report the case of a 68-year-old man who was referred to our Center in April 2013 af...

journal_title：Clinical chemistry and laboratory medicine

authors： Milani P,Valentini V,Ferraro G,Basset M,Russo F,Foli A,Palladini G,Merlini G

更新日期：2016-06-01 00:00:00

abstract：:The erythrocyte sedimentation rate (ESR), now more appropriately referred to as the "length of sedimentation reaction in blood (LSRB)", remains the most widely used laboratory test for monitoring the course of infections, inflammatory diseases and some types of cancer. Thanks to the several recently developed methods ...

journal_title：Clinical chemistry and laboratory medicine

authors： Piva E,Fassina P,Plebani M

更新日期：2002-07-01 00:00:00

abstract：:Historical research on the concept of normality, its roots and its development show that this concept has its sources in very different areas of scientific and medical thinking. Of great importance were: (i) a new theory of disease arising early in the 19th century supposing a continuous change from the healthy to the...

journal_title：Clinical chemistry and laboratory medicine

authors： Büttner J

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The clinical relevance of chromogranin A (CgA) concentrations depends on the analytical performance of the assay. The goal of the present study was to define the clinical involvements in CgA calibration models by evaluating the confidence intervals (CIs) for values from patients who were undergoing monitorin...

journal_title：Clinical chemistry and laboratory medicine

authors： Ferraro S,Marano G,Ciardi L,Vendramin C,Bongo AS,Bellomo G,Boracchi P,Biganzoli EM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Crimean-Congo hemorrhagic fever (CCHF) is a public health problem in many countries. Chitotriosidase (ChT) is an enzyme secreted by activated macrophages that catalyzes the hydrolysis of chitin and chitin-like substrates. The goal of this study was to assess the relationship between serum ChT activity and mo...

journal_title：Clinical chemistry and laboratory medicine

authors： Kurt YG,Cayci T,Onguru P,Akgul EO,Yaman H,Aydin I,Bodur H,Turker T,Kurt I,Cevik MA,Erbil MK

更新日期：2009-01-01 00:00:00

abstract：:The serum free light chain (FLC) assay has proven to be an important complementary test in the management of patients with monoclonal gammopathies. The serum FLC assay has value for patients with plasma cell disorders in the context of screening and diagnosis, prognostic stratification, and quantitative monitoring. No...

journal_title：Clinical chemistry and laboratory medicine

authors： Jacobs JF,Tate JR,Merlini G

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Extensive application of measurement of urinary iodine concentration (UIC) in several benign and malignant thyroid diseases could profit by the availability of rapid and inexpensive measuring techniques. Aim of this study was to apply a simple and inexpensive commercially available potentiometric method for ...

journal_title：Clinical chemistry and laboratory medicine

authors： Giovacchini G,Giovanella L,Haldemann A,Staub U,Füchsel FG,Koch P

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Crohn's disease (CD) is an incurable and difficult to diagnose condition. While high sensitive C-reactive protein (CRP) remains the best biochemical marker, we evaluated the diagnostic usefulness of lipid peroxidation indices. METHODS:Malondialdehyde/thiobarbituric acid-reactive substances (MDA/TBARS), pero...

journal_title：Clinical chemistry and laboratory medicine

authors： Boehm D,Krzystek-Korpacka M,Neubauer K,Matusiewicz M,Paradowski L,Gamian A

更新日期：2012-03-03 00:00:00

abstract：:Modifications in lipoprotein lipase levels lead to elevated triglycerides and reduced high density lipoprotein (HDL), both of which are risk factors for coronary artery disease (CAD). Hence, we examined the influence of the -93T/G, D9N, N291S, and S447X polymorphisms in the lipoprotein lipase (LPL) gene on CAD risk an...

journal_title：Clinical chemistry and laboratory medicine

authors： Ferencak G,Pasalić D,Grsković B,Cheng S,Fijal B,Sesto M,Skodlar J,Rukavina AS

更新日期：2003-04-01 00:00:00

abstract：:Many limitations and conflicting results have cast serious doubts on the validity of cerebrospinal fluid tau and Abeta42 levels for the biological diagnosis of Alzheimer's disease, particularly extreme variations of the reference limits found by unrelated groups as a consequence of different reference populations used...

journal_title：Clinical chemistry and laboratory medicine

authors： Burkhard PR,Fournier R,Mermillod B,Krause KH,Bouras C,Irminger I

更新日期：2004-04-01 00:00:00

abstract：:The clinical usefulness of C-reactive protein (CRP) and of transthyretin (TTR) for the early diagnosis and follow-up of infection after an open fracture was prospectively investigated (cohort A). It was complemented by a retrospective study of trauma patients admitted to an intensive care unit (cohort B). Serial deter...

journal_title：Clinical chemistry and laboratory medicine

authors： Férard G,Gaudias J,Bourguignat A,Ingenbleek Y

更新日期：2002-12-01 00:00:00

abstract：:The non-forage feeding of dairy cows rich in fast absorption carbohydrates, the low value of their euglycemic-hyperinsulinemic clamp suggest a dysregulation of carbohydrate metabolism able to produce neurodegenerative disorders. Comparisons between Alzheimer's disease developed in diabetes mellitus and bovine spongifo...

journal_title：Clinical chemistry and laboratory medicine

authors： Frey J

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Stone composition has changed substantially over the past decades in developed countries. We studied urinary stone composition in Tunisian children. METHODS:We studied 205 children ranging from 3 months to 16 years old age and who were diagnosed as having urinary stones (122 boys and 83 girls). Stone analys...

journal_title：Clinical chemistry and laboratory medicine

authors： Alaya A,Nouri A,Najjar MF

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:The IFCC Task Force on Clinical Applications of Cardiac Biomarkers suggests comparing several contemporary sensitive troponin assays in the same, sufficiently large reference population. METHODS:Three contemporary sensitive assays were used to measure troponin I concentration in samples from a uniquely larg...

journal_title：Clinical chemistry and laboratory medicine

authors： Petersmann A,Ittermann T,Fries C,Lubenow N,Kohlmann T,Kallner A,Greinacher A,Nauck M

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:In chronic kidney diseases of various etiologies, the urinary excretion of uromodulin is usually decreased in parallel with the glomerular filtration rate. This study aimed to investigate whether serum uromodulin is associated with kidney function. METHODS:Within the framework of the Seniorlabor study, a su...

journal_title：Clinical chemistry and laboratory medicine

authors： Risch L,Lhotta K,Meier D,Medina-Escobar P,Nydegger UE,Risch M

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Iodine requirements increase during pregnancy and previous studies have reported the inadequate iodine status of pregnant women in areas that have achieved iodine sufficiency in the general population. We examined the urinary iodine (UI) concentrations of pregnant women in Ukraine, where the iodine status is...

journal_title：Clinical chemistry and laboratory medicine

authors： Sekitani Y,Hayashida N,Takahashi J,Kozlovsky AA,Rudnitskiy S,Petrova A,Gutevych OK,Chorniy SA,Yamashita S,Takamura N

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The objective of the work was to study the manifestations of antiphospholipid syndrome (APS) in the Chinese population, and evaluate the ability of lupus anticoagulant (LAC) assays to identify APS. METHODS:Consecutive patients with APS from 2012 to 2015 in our hospital were recruited, strictly following the...

journal_title：Clinical chemistry and laboratory medicine

authors： Tang N,Sun Z,Yin S

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The measurement of serum IgE aids in the diagnosis and management of atopic allergic disease and hyper-IgE immunodeficiency syndromes. The 2nd World Health Organization (WHO) International Reference Reagent (IRR) for serum IgE (75/502; 5000 IU/ampoule), is widely used to calibrate assays for serum IgE. Exhau...

journal_title：Clinical chemistry and laboratory medicine

authors： Thorpe SJ,Heath A,Fox B,Patel D,Egner W

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Gastrointestinal toxicity is the principal toxicity of chemoradiation in the treatment of rectal carcinoma. The assessment of this toxicity still relies mostly on the symptoms reported by the patient. METHODS:Plasma citrulline, serum neopterin and urinary neopterin were followed weekly in 49 patients with r...

journal_title：Clinical chemistry and laboratory medicine

authors： Zezulová M,Bartoušková M,Hlídková E,Adam T,Kujovská Krčmová L,Červinková B,Solichová D,Zlevorová M,Cwiertka K,Friedecký D,Vrána D,Melichar B

更新日期：2016-02-01 00:00:00

abstract：:Cardiovascular risk is associated with high lipoprotein(a) (Lp(a)) concentrations and low molecular weight apolipoprotein(a) (apo(a)) isoforms. We studied the relationship between these two biological parameters, particularly in subjects expressing two apo(a) isoforms. Plasma Lp(a) was measured by immunonephelometry i...

journal_title：Clinical chemistry and laboratory medicine

authors： Alaoui M,Merle C,Garnotel R,Jolly D,Durlach V,Gillery P

更新日期：2003-05-01 00:00:00

abstract：:Age-related variation of the urinary excretion of amino acids has been widely reported. Instead of the conventional reference intervals, continuous reference limits might be a more practical approach during periods of rapid changes such as infancy or childhood. Regression-based reference limits have been produced for ...

journal_title：Clinical chemistry and laboratory medicine

authors： Venta R,Prieto B,Alvarez FV

更新日期：2002-04-01 00:00:00

abstract：:The pathogenesis of cobalamin (Cbl)-deficient (Cbl-D) neuropathy and the role of normal prions (PrPcs) in myelin maintenance are both subjects of debate. We have demonstrated that Cbl deficiency damages myelin by increasing tumor necrosis factor (TNF)-α, and decreasing epidermal growth factor (EGF) levels in the rat c...

journal_title：Clinical chemistry and laboratory medicine

authors： Scalabrino G,Veber D

更新日期：2013-03-01 00:00:00

abstract：:Total prostate-specific antigen (PSA) and complexed PSA were determined in venous blood from 12 patients with prostate cancer before and after radical prostatectomy by using Immuno 1 PSA assays. The elimination kinetics of complexed PSA were compared with that of total PSA. Nearly constant concentrations of complexed ...

journal_title：Clinical chemistry and laboratory medicine

authors： Stephan C,Jung K,Brux B,Lein M,Sinha P,Schnorr D,Loening SA

更新日期：2000-04-01 00:00:00

abstract：:The soluble transferrin receptor (sTfR) distinguishes iron deficiency anemia from other types of anemia. Refractory iron deficiency anemia is often the onset symptom in malabsorption-induced celiac disease. We evaluated whether sTfR levels distinguish celiac disease-associated iron deficiency anemia from iron deficien...

journal_title：Clinical chemistry and laboratory medicine

authors： De Caterina M,Grimaldi E,Di Pascale G,Salerno G,Rosiello A,Passaretti M,Scopacasa F

更新日期：2005-01-01 00:00:00

abstract：:Homocysteine is a risk factor for ischemic heart disease; similarly as is hyperlipidemia or insulin resistance, which frequently occur in women with polycystic ovary syndrome. We examined the relationships between thiols and hormonal status or insulin resistance in 40 women (aged 25.8 +/- 7 years) with polycystic ovar...

journal_title：Clinical chemistry and laboratory medicine

authors： Vrbíková J,Tallová J,Biciková M,Dvoráková K,Hill M,Stárka L

更新日期：2003-02-01 00:00:00