Elimination of serum complexed prostate-specific antigen after radical retropubic prostatectomy.

abstract：:Recent progress in the understanding of the pathophysiology of hemostasis has established that blood coagulation disorders causing bleeding or thrombosis often indicate a multi-casual nature in which the interaction between genetic and acquired factors plays a major mechanistic role. The interaction of two or more fac...

journal_title：Clinical chemistry and laboratory medicine

authors： Franchini M,Mannucci PM

更新日期：2009-01-01 00:00:00

abstract：:Primary biliary cholangitis (PBC), also known as primary biliary cirrhosis, is an autoimmune disease of the liver characterized by anti-mitochondrial antibodies (AMA) in 90%-95% of patients. The aim of this study was to evaluate the diagnostic value of several serum biomarkers in patients with PBC but negative for AMA...

journal_title：Clinical chemistry and laboratory medicine

authors： de Liso F,Matinato C,Ronchi M,Maiavacca R

更新日期：2017-11-27 00:00:00

abstract：:A questionnaire to assess knowledge of the expected elevation in serum K measurement with different grades of hemolysis was administered to medical technologists working in biochemistry laboratories, hospital physicians and nurses. The questions involved different grades of hemolysis (mild, 1.0, moderate, 2.5 and seve...

journal_title：Clinical chemistry and laboratory medicine

authors： Hawkins RC

更新日期：2005-01-01 00:00:00

abstract：:The aim of this work was to assess the diagnostic value of anti-CCP-3 and anti-CCP-2 for the diagnosis of rheumatoid arthritis (RA) and determine whether anti-CCP-3 more accurately identifies patients with rheumatoid arthritis than anti-CCP-2. PubMed and CNKI databases were searched for studies published in English an...

journal_title：Clinical chemistry and laboratory medicine

authors： Zhang WC,Wu H,Chen WX

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Mid-regional pro-adrenomedullin (MR-proADM) and endothelin-1 have been shown to predict mortality of patients with acute myocardial infarction. However, the prognostic value of both biomarkers in predicting long-term clinical events after acute myocardial infarction remains unclear. METHODS:In a prospective...

journal_title：Clinical chemistry and laboratory medicine

authors： Behnes M,Papassotiriou J,Walter T,Fiedler E,Sauer T,Lang S,Elmas E,Hoffmann U,Borggrefe M,Brueckmann M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The Sysmex DI-60 system (DI-60, Sysmex, Kobe, Japan) is a new automated digital cell imaging analyzer. We explored the performance of DI-60 in comparison with Sysmex XN analyzer (XN, Sysmex) and manual count. METHODS:In a total of 276 samples (176 abnormal and 100 normal samples), white blood cell (WBC) dif...

journal_title：Clinical chemistry and laboratory medicine

authors： Kim HN,Hur M,Kim H,Kim SW,Moon HW,Yun YM

更新日期：2017-11-27 00:00:00

abstract：BACKGROUND:The European Society for Pediatric Gastroenterology and Nutrition states that if IgA anti-tissue transglutaminase (tTG) exceeds 10 times the upper limit of normal (ULN), there is the possibility to diagnose celiac disease (CD) without duodenal biopsy, if supported by anti-endomysium testing and human leukocy...

journal_title：Clinical chemistry and laboratory medicine

authors： Oyaert M,Vermeersch P,De Hertogh G,Hiele M,Vandeputte N,Hoffman I,Bossuyt X

更新日期：2015-09-01 00:00:00

abstract：:Increased expression of sialyl Lewis X or A antigens on metastatic cancer cells leads to their selectin-mediated extravasation. Profound fucosylation of the serum microenvironment may be a factor that interrupts adhesion and influences the formation of metastases. In this study we quantitatively analyzed fucosylation ...

journal_title：Clinical chemistry and laboratory medicine

authors： Kossowska B,Ferens-Sieczkowska M,Gancarz R,Passowicz-Muszyńska E,Jankowska R

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The objective of the study was to find the incidence of hemolysis in samples transported through a pneumatic tube system (PTS) at different speeds. METHODS:This prospective observational study was done in three phases: "short distance and high speed (115 m at 3 m/s)", "long distance and high speed (225 m at...

journal_title：Clinical chemistry and laboratory medicine

authors： Tiwari AK,Pandey P,Dixit S,Raina V

更新日期：2011-11-10 00:00:00

abstract：:Iron status in man is influenced by environmental and genetic factors. The molecular variation of haptoglobin is one of the genetic factors influencing iron status in Caucasians. Differences in iron metabolism between blacks and whites have been reported. We wanted to investigate the effect of haptoglobin polymorphism...

journal_title：Clinical chemistry and laboratory medicine

authors： Kasvosve I,Gordeuk VR,Delanghe JR,Gomo ZA,Gangaidzo IT,Khumalo H,Moyo VM,Saungweme T,Mvundura E,Boelaert JR

更新日期：2002-08-01 00:00:00

abstract：:For several years it has been possible to routinely detect numerous mutations in the human genome by different methods. The most common technique is a standard PCR, but real time fluorescence PCR is increasingly being used. The purpose of this paper is to compare these two different techniques from the point of view o...

journal_title：Clinical chemistry and laboratory medicine

authors： Schroell-Metzger B,Dicato M,Bosseler M,Berchem G

更新日期：2003-04-01 00:00:00

abstract：Objectives:Monoclonal immunoglobulins can cause interference in many laboratory analyses. During a 4 month period we observed seven patients with monoclonal disease and falsely extremely elevated 25-hydroxyvitamin D (25(OH)D) results above 160 ng/mL (>400 nmol/L) measured using an immunoassay from Abbott Diagnostics. B...

journal_title：Clinical chemistry and laboratory medicine

authors： Hager HB,Bolstad N,Warren DJ,Ness MV,Seierstad B,Lindberg M

更新日期：2020-10-29 00:00:00

abstract：:Many limitations and conflicting results have cast serious doubts on the validity of cerebrospinal fluid tau and Abeta42 levels for the biological diagnosis of Alzheimer's disease, particularly extreme variations of the reference limits found by unrelated groups as a consequence of different reference populations used...

journal_title：Clinical chemistry and laboratory medicine

authors： Burkhard PR,Fournier R,Mermillod B,Krause KH,Bouras C,Irminger I

更新日期：2004-04-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is a sight threatening eye disease that affects millions of humans over the age of 65 years. It is considered to be the major cause of irreversible blindness in the elderly population in the developed world. The disease is prevalent in Europe and the United States, which has a la...

journal_title：Clinical chemistry and laboratory medicine

authors： Kokotas H,Grigoriadou M,Petersen MB

更新日期：2011-04-01 00:00:00

abstract：:Background Aberrant kallikrein activity is observed in a number of inflammatory dermatoses. Up-regulation of kallikrein-5 (KLK5) activity leads to uncontrolled skin desquamation and cleavage of proteinase-activated receptor-2 (PAR2), causing the release of pro-inflammatory cytokines and disruption of epidermal barrier...

journal_title：Clinical chemistry and laboratory medicine

authors： Di Paolo CT,Filippou PS,Yu Y,Poda G,Diamandis EP,Prassas I

更新日期：2019-10-25 00:00:00

abstract：:Small dense low-density lipoproteins (LDLs) have been associated with coronary heart disease (CHD) and type 2 diabetes in previous studies. However, the significance of small dense LDLs as a coronary risk factor for subjects with type 2 diabetes remains unclear. We measured mean LDL particle diameter by gradient gel e...

journal_title：Clinical chemistry and laboratory medicine

authors： Yoon Y,Song J,Park HD,Park KU,Kim JQ

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Heparin is the standard drug for anticoagulation treatment and is used in many cardiac surgical interventions to prevent blood clotting. The anticoagulation status is controlled by various clotting tests. However, these tests depend on parameters like temperature, hemodilution etc. and are thus not applicabl...

journal_title：Clinical chemistry and laboratory medicine

authors： Haselbach S,Maurer J,Vogel V,Harder S,Weber CF,Baykut D,Meininger D,Keller H,Moritz A,Mäntele W

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Adult-type hypolactasia is characterized by the inability to digest lactose during adulthood, due to lactase (LCT) deficiency. It is usually diagnosed by the measurement of breath hydrogen increase after a lactose load (breath hydrogen test, BHT). A substitution of C to T at position -13910 bp upstream the L...

journal_title：Clinical chemistry and laboratory medicine

authors： Mottes M,Belpinati F,Milani M,Saccomandi D,Petrelli E,Calacoci M,Chierici R,Pignatti PF,Borgna-Pignatti C

更新日期：2008-01-01 00:00:00

abstract：:Adequate volume loading may be the most important step in the treatment of patients with septic shock. Techniques allowing us to achieve and tightly control volume loading and regional perfusion are considered to be helpful. An elevated oxygen delivery may be beneficial in some patients but the increase of oxygen deli...

journal_title：Clinical chemistry and laboratory medicine

authors： Meier-Hellmann A,Sakka S,Reinhart K

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:The objective of the present study was to calculate age- and gender-specific reference ranges for serum insulin-like growth factor I (IGF-I) and insulin-like growth factor binding protein 3 (IGFBP-3) concentrations using quantile regression. METHODS:From the Study of Health in Pomerania (SHIP), 1798 men and...

journal_title：Clinical chemistry and laboratory medicine

authors： Friedrich N,Krebs A,Nauck M,Wallaschofski H

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:A large body of evidence suggests that not only cerebral but also systemic oxidative stress (OxS) might be involved in the pathogenesis of late onset Alzheimer's disease (LOAD) and vascular dementia (VAD), as well as of the prodromal phase of dementia, the so-called mild cognitive impairment (MCI). In the pr...

journal_title：Clinical chemistry and laboratory medicine

authors： Cervellati C,Romani A,Bergamini CM,Bosi C,Sanz JM,Passaro A,Zuliani G

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMPs), especially MMP-2 and MMP-9, play an important role in tumor invasion and metastasis. This study aimed to determine the serum levels of MMP-2, MMP-9, 130- and 225-kDa gelatinolytic bands and conventional tumor markers, carcinoembryonic antigen (CEA) and cancer antigen (CA) 19...

journal_title：Clinical chemistry and laboratory medicine

authors： Emara M,Cheung PY,Grabowski K,Sawicki G,Wozniak M

更新日期：2009-01-01 00:00:00

abstract：:Background This study aimed to investigate the correlation between glucose fluctuation from self-monitored blood glucose (SMBG) and the major adverse cardiac events (MACE) in diabetic patients with acute coronary syndrome (ACS) during a 6-month follow-up period using the WeChat application. Methods From November 2016 ...

journal_title：Clinical chemistry and laboratory medicine

authors： Xia J,Hu S,Xu J,Hao H,Yin C,Xu D

更新日期：2018-11-27 00:00:00

abstract：:Haemophilia A is the most common inherited bleeding disorder caused by defects in the F8C gene that encodes coagulation factor VIII. This X-linked recessive disorder occurs in approximately 1:5000 males. Haemophilia A is diagnosed based on normal prothrombin time, altered activated partial thromboplastin time and redu...

journal_title：Clinical chemistry and laboratory medicine

authors： Castaldo G,D'Argenio V,Nardiello P,Zarrilli F,Sanna V,Rocino A,Coppola A,Di Minno G,Salvatore F

更新日期：2007-01-01 00:00:00

abstract：:Background For pregnant women with suspected preeclampsia, the soluble fms-like tyrosine-kinase 1 (sFlt-1)/placental growth factor (PlGF) ratio is a biomarker to aid diagnosis. We performed method comparisons between Elecsys® and Kryptor sFlt-1 and PlGF immunoassays and assessed the diagnostic performance for preeclam...

journal_title：Clinical chemistry and laboratory medicine

authors： Stepan H,Hund M,Dilba P,Sillman J,Schlembach D

更新日期：2019-08-27 00:00:00

abstract：BACKGROUND:Query fever (Q fever) is a zoonotic infection, caused by the intracellular Gram-negative coccobacillus Coxiella burnetii. From 2007 until 2010, a large Q fever outbreak has occurred in the Netherlands. We studied traditional and less common inflammation markers in seronegative and seropositive patients with ...

journal_title：Clinical chemistry and laboratory medicine

authors： Vissers E,de Jager CP,Hilbink M,Kusters R,van Gageldonk-Lafeber AB,Wever PC

更新日期：2012-02-04 00:00:00

abstract：:Low-density lipoprotein (LDL) oxidation in vivo depends on lipid composition and on plasma antioxidant status. The aim of our study was to investigate the relationship between plasma lipid composition and LDL oxidation and, in particular, to explore whether LDL-cholesterol/triglycerides ratio (LDL-C/TG) and LDL-choles...

journal_title：Clinical chemistry and laboratory medicine

authors： Brizzi P,Tonolo G,Carusillo F,Malaguarnera M,Maioli M,Musumeci S

更新日期：2003-01-01 00:00:00

abstract：:The mutant of CYP2D6*3 allele with A2637 deletion in exon 5 and the mutant of CYP2D6*4 allele G1934-->A, splice site defect are among the most common polymorphic alleles of CYP2D6 gene, resulting in a decreased or no activity of CYP isoenzyme. In this study, a reliable polymerase chain reaction-restriction fragment le...

journal_title：Clinical chemistry and laboratory medicine

authors： Topić E,Stefanović M,Nikolić V,Zoricić I,Ivanisević AM,Zuntar I

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:We evaluated the effect of kidney glomerular function on serum concentrations of human epididymis protein 4 (HE4) using creatinine (Cr), cystatin C (CysC) and related chronic kidney disease epidemiology collaboration (CKD-EPI) equations. METHODS:We enrolled 101 women aged ≤56 years with a glomerular filtrat...

journal_title：Clinical chemistry and laboratory medicine

authors： Ferraro S,Pasqualetti S,Carnevale A,Panteghini M

更新日期：2016-10-01 00:00:00

abstract：:Background Patients with cystic fibrosis (CF) have a reduced intestinal absorption of cholesterol and in a preliminary study we observed differences in plasma sterol profile between patients with pancreatic sufficiency (PS) and those with pancreatic insufficiency (PI). Therefore, we hypothesized that the sterol analys...

journal_title：Clinical chemistry and laboratory medicine

authors： Gelzo M,Iacotucci P,Sica C,Liguori R,Comegna M,Carnovale V,Dello Russo A,Corso G,Castaldo G

更新日期：2020-09-25 00:00:00