Abstract：
:Etch-and-rinse adhesives can cause vasorelaxation via mechanisms occurring in the endothelium and smooth muscle, including the release of nitric oxide (NO). This effect might promote or aggravate bleeding if such adhesives are placed inadvertently on iatrogenic pulp microexposures. The present study assessed the vasoactive potential of a newer generation self-etch adhesive, Clearfil Protect Bond (CPB), on isolated rat aorta. Cumulative concentrations of the primer, bond, and mixture of CPB elicited concentration-dependent relaxation of phenylephrine-induced active tonus in the rat aorta, demonstrating that the tested self-etch adhesive can lead to vasorelaxation of pulp vessels that is mediated by Ca(2+) antagonistic effect. The vasorelaxant effect of CPB or its components was mediated neither via endothelium-dependent NO and prostanoid-dependent mechanisms nor by K(+) efflux through K(+) channels. Mechanical removal of the endothelium did not significantly alter the relaxation induced by CPB. Assuming these data can be extrapolated to the clinical situation, CPB, either in mixed form or by its components, can lead to vasorelaxation of pulp vessels that is mediated by a Ca(2+) antagonistic effect. If CPB is placed inadvertently on pulp microexposures during direct pulp capping, this effect might promote bleeding that might impair healing and, via plasma exatravasation, might compromise resin infiltration and polymerization.
journal_name
J Endodjournal_title
Journal of endodonticsauthors
Basak F,Vural IM,Kaya E,Ulku C,Guven G,Cehreli SB,Cehreli ZC,Seyrek M,Yildiz Odoi
10.1016/j.joen.2008.07.019subject
Has Abstractpub_date
2008-10-01 00:00:00pages
1202-6issue
10eissn
0099-2399issn
1878-3554pii
S0099-2399(08)00629-8journal_volume
34pub_type
杂志文章abstract：:The purpose of this study was to compare the cleaning efficacy of passive ultrasonic activation with that of passive sonic activation after hand instrumentation. Sixty curved molar canals were hand-instrumented to size 35 and divided into three groups. Group 1 received no further treatment. Group 2 received 3 min of p...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(99)80120-4
更新日期：1999-11-01 00:00:00
abstract：:The purpose of this study was to compare the degree of anesthesia obtained with 2% lidocaine with three different concentrations of epinephrine for inferior alveolar nerve block. Using a repeated measures design, 30 subjects randomly received an inferior alveolar injection using masked cartridges of each solution at t...
journal_title：Journal of endodontics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/S0099-2399(97)80271-3
更新日期：1997-03-01 00:00:00
abstract：:The bond strength of ActiV GP root canal filling system and gutta-percha/AH plus sealer when used after final rinse with different irrigation protocols was evaluated in this study. Forty roots were randomly divided into four groups (n = 10) according to the final irrigation regimen: group 1, 5 mL 17% EDTA; group 2, 5 ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2009.01.003
更新日期：2009-04-01 00:00:00
abstract：INTRODUCTION:Instrumentation of the mesial root canal system of mandibular molars may hinder disinfection by packing hard tissue debris within the isthmuses. The removal of accumulated hard tissue debris (AHTD) by 3 supplemental irrigation systems, 2 ultrasonically activated and 1 multisonic, was assessed with micro-co...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2019.03.013
更新日期：2019-07-01 00:00:00
abstract：:Calcium hydroxide is the "gold standard" endodontic medication, but it may fail to eliminate certain facultative bacteria and yeasts found in root canal systems. In this study, standardized bovine dentin blocks infected with Enterococcus faecalis were treated with an aqueous calcium hydroxide or bioactive glass S53P4 ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200404000-00009
更新日期：2004-04-01 00:00:00
abstract：:The aim of this in vitro study was to determine whether irrigation with apical negative pressure was more effective than traditional positive-pressure irrigation in eradicating Enterococcus faecalis from preshaped root canals. Fifty-four extracted mandibular molars were instrumented to produce either a non-tapered or ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2008.07.022
更新日期：2008-11-01 00:00:00
abstract：INTRODUCTION:The purpose of this in vivo study was to evaluate the accuracy of small-volume cone-beam computed tomographic (CBCT) imaging compared with conventional periapical radiography (CPR) in the diagnosis of vertical root fractures (VRFs) using exploratory surgery as the reference standard. METHODS:Eighty-two de...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2020.04.015
更新日期：2020-08-01 00:00:00
abstract：:The purpose of this study was to compare ultrasonic and high-speed-bur root-end preparations. Seventy-six roots from 29 bilaterally matched pairs of human teeth in cadavers were used in this study. In group 1 ultrasonic preparations were made in 38 roots and filled with amalgam. In group 2 high-speed bur preparations ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/s0099-2399(97)80301-9
更新日期：1997-07-01 00:00:00
abstract：:The anatomy of third molars has been described as unpredictable. However restorative, prosthetic, and orthodontic considerations often require endodontic treatment of third molars in order for them to be retained as functional components of the dental arch. The purpose of this study was to investigate and characterize...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200011000-00011
更新日期：2000-11-01 00:00:00
abstract：INTRODUCTION:Two groups of patients with orofacial pains that are clinically important to distinguish from each other are patients with odontogenic pain and temporomandibular disorder (TMD) pain. The aim of this study was to determine the sensitivity and specificity of 2 screening instruments in distinguishing between ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2016.10.001
更新日期：2017-01-01 00:00:00
abstract：INTRODUCTION:The retrieval of fractured instruments from root canals has been largely reported in the literature. However, a less complex retrieval method that causes minimum damage to the dental structures is needed. The aim of this article is to introduce a new concept of retrieval of fractured instruments from root ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2009.11.024
更新日期：2010-04-01 00:00:00
abstract：INTRODUCTION:The purpose of this study was to evaluate the push-out bond strengths of different obturating materials. METHODS:Forty single-rooted human extracted teeth were used in this study. The teeth were instrumented and irrigated by using 5.25% NaOCl, 15% ethylenediaminetetraacetic acid, and sterile water. The te...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2009.10.026
更新日期：2010-02-01 00:00:00
abstract：INTRODUCTION:This study assessed apical extrusion during treatment with GentleWave (GW; Sonendo Inc, Laguna Hills, CA), a conventional open-ended 30-G needle (CN), or Endovac (EV; SybronEndo, Orange, CA) in root canals enlarged to different dimensions with and without apical constriction. METHODS:Sixteen mandibular mo...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2015.04.009
更新日期：2016-01-01 00:00:00
abstract：INTRODUCTION:The purpose of this prospective, randomized, single-blinded study was to measure the degree of anesthesia obtained with 1.8 mL and 3.6 mL of 2% lidocaine with 1:100,000 epinephrine in posterior superior alveolar (PSA) nerve blocks. METHODS:Thirty-one adult subjects randomly received PSA nerve blocks of 1....
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2010.01.009
更新日期：2010-04-01 00:00:00
abstract：INTRODUCTION:The purpose of this study was to compare the accuracy of the Root ZX II Apex Locator (RZX), the Elements Apex Locator (ELE), and the Precision Apex Locator (PAL). METHODS:Forty single-rooted extracted teeth were decoronated and the root canals coronally flared. Actual canal lengths were determined by inse...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2009.09.016
更新日期：2010-02-01 00:00:00
abstract：INTRODUCTION:The purpose of this study was to establish a stable experimental mice pulpal inflammatory model and to evaluate inflammatory reactions of pulpal tissue after pulpal exposure. METHODS:Pulpal inflammation was induced in 80 C57BL/6 mice by occlusal exposure of the pulp of the maxillary first molar. The mice ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2016.09.003
更新日期：2017-01-01 00:00:00
abstract：INTRODUCTION:Growth and differentiation factor-5 (GDF-5) is a multifunctional protein that regulates the development and repair in many tissues. The purpose of this study was to investigate whether GDF-5 may influence the proliferation, differentiation, and collagen turnover of human dental pulp cells. METHODS:Human d...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2013.06.003
更新日期：2013-10-01 00:00:00
abstract：INTRODUCTION:An accurate differential diagnosis of apical periodontitis (AP) and nasopalatine duct cyst (NPDC) should be established to define the best treatment for endodontically treated maxillary anterior teeth with apical periodontitis. Three-dimensional cone beam computed tomography (CBCT) images help to plan trea...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.11.022
更新日期：2011-03-01 00:00:00
abstract：INTRODUCTION:The aim was to present a novel surgical technique using virtually preplanned 3-dimensional (3D)-printed templates for guided osteotomies. These were to ensure atraumatic uncovering of a severely impacted donor tooth including guided drilling of the recipient alveolus followed by a secure autotransplantatio...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2020.07.024
更新日期：2020-07-29 00:00:00
abstract：:The antibacterial activity of three commercial 10% carbamide peroxide bleaching agents (Nite White, Karisma, and Opalescence) on Streptococcus mutans, Streptococcus mitis, Streptococcus sanguis, Lactobacillus casei, and Lactobacillus acidophilus was examined. Chlorhexidine (0.2%) was used as a positive control. Test m...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(96)80217-2
更新日期：1996-07-01 00:00:00
abstract：INTRODUCTION:Experimental studies show that dental pulp cells respond unfavorably to contact with resin composite restorative material. Hypothetically, in a random population, the frequency of apical periodontitis should be higher for teeth restored with resin composite than with amalgam. Therefore, the aim was to comp...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2014.05.002
更新日期：2014-09-01 00:00:00
abstract：:Many root canal instruments with several different designs have been introduced during recent years. This article evaluates the machining properties of four such instruments: the Flex-R, K-Flex, Trio-Cut, and S file. There are large variations in the machining properties of these instruments. The results are comparabl...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/s0099-2399(07)80200-7
更新日期：1990-12-01 00:00:00
abstract：INTRODUCTION:The purpose of this study was to evaluate the effects of endodontic irrigants on the push-out strength and hydration behavior of accelerated mineral trioxide aggregate (MTA) in its early setting phase. METHODS:In an in vitro perforation model, MTA with or without 10% CaCl(2) was condensed and allowed to i...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2010.08.039
更新日期：2010-12-01 00:00:00
abstract：:This study was conducted to evaluate the influence of immediate versus delayed immersion time, and passive dye immersion versus centrifuged dye on apical leakage measurements. Eighty-four extracted human teeth with single straight canals were instrumented and divided into four experimental groups of 20 teeth each plus...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)81364-6
更新日期：1993-07-01 00:00:00
abstract：INTRODUCTION:There are no long-term, prospective clinical studies assessing outcomes of endodontically treated cracked teeth with radicular extensions. The purpose of this prospective study was to examine the 2- to 4-year success and survival rates of endodontically treated, coronally restored, cracked teeth, specifica...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2019.03.015
更新日期：2019-07-01 00:00:00
abstract：INTRODUCTION:Anesthetic efficacy of inferior alveolar nerve block decreases in patients with irreversible pulpitis. It was hypothesized that premedication with nonsteroidal anti-inflammatory drugs might improve the success rates in patients with inflamed pulps. METHODS:Sixty-nine adult volunteers who were actively exp...
journal_title：Journal of endodontics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.joen.2009.11.010
更新日期：2010-03-01 00:00:00
abstract：INTRODUCTION:Difficult handling, long setting time, and potential discoloration are important drawbacks of white mineral trioxide aggregate (WMTA). The development of Biodentine, a recently developed calcium silicate-based material (CSM), has overcome some of these shortcomings; however, there are no available data on ...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2012.12.021
更新日期：2013-04-01 00:00:00
abstract：:Endodontic fillings were challenged with bacterial ingress in mandibular premolars of 4 beagle dogs. Groups 1, 2, and 3 (n = 9), had canals filled with gutta-percha and sealer, gutta-percha alone, and sealer alone, respectively. After 2 wk, pulp chambers were inoculated with plaque. Group 4 (n = 9) and group 5 (n = 5)...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/S0099-2399(06)81120-9
更新日期：1997-09-01 00:00:00
abstract：:Whole genome DNA-DNA hybridization has been used to identify bacteria in periradicular lesions partly because there is no amplification of the bacteria, therefore, minor contaminants are not detected. There are, however, potential pitfalls with this technique, including inability to distinguish dead bacteria, cross-re...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1097/00004770-200407000-00014
更新日期：2004-07-01 00:00:00
abstract：INTRODUCTION:Pulp capping materials allow healing of injured pulp with a layer of reparative dentin. Glucose is needed to cure the injured area. Glucose is transported by glucose transporter (Glut) 2 and Glut4, which are transmembrane proteins that act as gatekeepers. We hypothesized that the transport of glucose via G...
journal_title：Journal of endodontics
pub_type： 杂志文章
doi：10.1016/j.joen.2019.10.003
更新日期：2020-01-01 00:00:00
