Abstract:
:Certain cognitive functions differ in men and women, although the anatomical and functional substrates underlying these differences remain unknown. Because neocortical activity is directly related with higher brain function, numerous studies have focused on the cerebral cortex when searching for possible structural correlates of cognitive gender differences. However, there are no studies on possible gender differences at the synaptic level. In the present work we have used stereological and correlative light and electron microscopy to show that men have a significantly higher synaptic density than women in all cortical layers of the temporal neocortex. These differences may represent a microanatomical substrate contributing to the functional gender differences in brain activity.
journal_name
Proc Natl Acad Sci U S Aauthors
Alonso-Nanclares L,Gonzalez-Soriano J,Rodriguez JR,DeFelipe Jdoi
10.1073/pnas.0803652105subject
Has Abstractpub_date
2008-09-23 00:00:00pages
14615-9issue
38eissn
0027-8424issn
1091-6490pii
0803652105journal_volume
105pub_type
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