Major achievements and experience in filariasis control in the People's Republic of China. National Technical Steering Group for Filariasis Control and Research.

abstract：BACKGROUND:The myocardial ATP sensitive potassium channel (K(ATP) channel) has been known for more than two decades, the properties of this channel have been intensively investigated, especially the myocardial protection effect by opening this channel. Numerous studies, including hypothermic, using K(ATP) agonists to a...

journal_title：Chinese medical journal

authors： Jin SQ,Niu LJ,Deng CY,Yao ZB,Zhou YJ

更新日期：2006-10-20 00:00:00

abstract：BACKGROUND:Continuous interscalene nerve block (CISB) is considered to be the most effective method for postoperative analgesia after shoulder surgery with prolonged severe pain. This study was performed to evaluate the minimum effective background infusion rate and the effective background infusion rate of ropivacaine...

journal_title：Chinese medical journal

authors： Wei Y,Li M,Rong Y,Guo X

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of active immunotherapy with anti-idiotypic vaccine in patients with nasopharyngeal carcinoma (NPC). METHODS:Anti-idiotypic antibodies (2H4/5D3) bearing the internal image of the NPC antigen were used in active immunotherapy in NPC patients receiving radiotherapy. Antibodies and cyt...

journal_title：Chinese medical journal

authors： Li G,Xie L,Zhou G,Fu H,Zhou J,Sun Q

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:There are more than 300 genetic loci that have been found to be related to hereditary hearing impairment (HHI), including 92 causative genes for nonsyndromic hearing loss, among which 34 genes are related to autosomal dominant nonsyndromic HHI (ADNSHHI). Traditional linkage analysis and candidate gene sequen...

journal_title：Chinese medical journal

authors： Wang HY,Zhao YL,Liu Q,Yuan H,Gao Y,Lan L,Yu L,Wang DY,Guan J,Wang QJ

更新日期：2015-12-20 00:00:00

abstract：OBJECTIVE:To isolate and clone the tumor suppressor gene on chromosomal region 7q32 correlated with the carcinogenesis of human nasopharyngeal carcinoma (NPC). METHODS:The genotypes of polymorphic microsatellite markers on 7q32 in DNA from 24 biopsies of nasopharyngeal carcinoma and matched normal blood cells were ide...

journal_title：Chinese medical journal

authors： Jiang N,Zhan F,Tan G,Deng L,Zhou M,Cao L,Qiu Y,Xie Y,Li G

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Pelizaeus-Merzbacher disease (PMD) is a rare X-linked recessive disorder with symptoms including nystagmus, impaired motor development, ataxia, and progressive spasticity. The proteolipid protein 1 (PLP1) gene is the only pathogenic gene of PMD. Duplication of the PLP1 gene is the most frequent gene defect, ...

journal_title：Chinese medical journal

authors： Wang JM,Wu Y,Wang HF,Deng YH,Yang YL,Qin J,Li XY,Wu XR,Jiang YW

更新日期：2008-09-05 00:00:00

abstract：OBJECTIVE:To determine the relationship between remodeling and dysfunction of left ventricle (LV) and the expression of the angiotensin II AT1 receptor mRNA after myocardial infarction (MI) in rats. METHODS:Nine MI rats (Group A) and 8 sham-operated rats (Group B) were studied by both Doppler echocardiography and Dot ...

journal_title：Chinese medical journal

authors： Zhang G,Yang Y,Pu S,Shen X,Peng T,Chen H

更新日期：1999-07-01 00:00:00

abstract：:An epidemiological study on the incidence and prevalence of Parkinson's disease (PD) was carried out in 29 provinces, cities and autonomous regions in this country in 1986. The survey was conducted in 117 areas, and 566 patients with PD were found among 3,869,162 persons examined, giving a point prevalence for men and...

journal_title：Chinese medical journal

authors： Wang YS,Shi YM,Wu ZY,He YX,Zhang BZ

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Prostate specific membrane antigen (PSMA) can facilitate the growth, migration, and invasion of the LNCaP prostate cancer cell lines, but the underlying molecular mechanisms have not yet been clearly defined. Here, we investigated whether PSMA serves as a novel regulator of the phosphatidylinositol 3-kinase ...

journal_title：Chinese medical journal

authors： Guo Z,Lai Y,Du T,Zhang Y,Chen J,Bi L,Lin T,Liu H,Wang W,Xu K,Jiang C,Han J,Zhang C,Dong W,Huang J,Huang H

更新日期：2014-01-01 00:00:00

abstract：: ...

journal_title：Chinese medical journal

authors： Zeng XX,Liu J,Ma L,Fu P

更新日期：2018-11-20 00:00:00

abstract：:Ninety-five patients with perforation, hemorrhage or stenosis due to duodenal ulcer were treated by extended parietal cell vagotomy. Postoperative follow-up ranged from 3.5 to 10 years (mean 6 years) in 88 patients (92%) with acute perforation (60), hemorrhage (8) and stenosis (20). There was no operative mortality. U...

journal_title：Chinese medical journal

authors： Li SY,An P,Liang ZJ,Yuan SJ,Yu J

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Primary systemic light chain amyloidosis (AL) is a rare plasma cell disease, our purpose was to analyze the immunophenotypic characteristics of the plasma cells in bone marrow in AL patients, and explore whether the detection of abnormal plasma cell clones in bone marrow by flow cytometry (FCM) could be used...

journal_title：Chinese medical journal

authors： Hu Y,Wang M,Chen Y,Chen X,Fang F,Liu S,Zhang Y,Wu X,Zhu P

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:This study was to examine the expression of total vascular endothelial growth factor (VEGF) and the anti-angiogenic VEGF 165 b isoform in the vitreous body of retinopathy of prematurity (ROP) patients, and to further study the role of the VEGF splicing in the development of ROP. METHODS:This was a prospecti...

journal_title：Chinese medical journal

authors： Zhao M,Xie WK,Bai YJ,Huang LZ,Wang B,Liang JH,Yin H,Li XX,Shi X

更新日期：2015-09-20 00:00:00

abstract：BACKGROUND:Acinetobacter baumannii is one of the main gram-negative bacilli in clinical practice. Nosocomial infections caused by multi-drug resistance Acinetobacter baumannii is very difficult to treat. This study was designed to investigate the antimicrobial resistance characteristics and four resistant gene expressi...

journal_title：Chinese medical journal

authors： Shi WF,Jiang JP,Mi ZH

更新日期：2005-01-20 00:00:00

abstract：BACKGROUND:Our previous studies have shown that regulatory factor X5 (RFX5), a classical transcription regulator of MHCII genes, was obviously overexpressed in hepatocellular carcinoma (HCC) tumors. However, the role of RFX5 in the carcinogenesis and progress of HCC remains unknown. This study aimed to reveal its biolo...

journal_title：Chinese medical journal

authors： Chen DB,Zhao YJ,Wang XY,Liao WJ,Chen P,Deng KJ,Cong X,Fei R,Wu X,Shao QX,Wei L,Xie XW,Chen HS

更新日期：2019-07-05 00:00:00

abstract：BACKGROUND:Although acute congestive heart failure (CHF) patients typically present with abnormal auscultatory findings on lung examination, lung sounds are not normally subjected to rigorous analysis. The goals of this study were to use a computerized analytic acoustic tool to evaluate lung sound patterns in CHF patie...

journal_title：Chinese medical journal

authors： Wang Z,Xiong YX

更新日期：2010-05-05 00:00:00

abstract：BACKGROUND:Pancreatic cancer is one of the most lethal human cancers with a very low survival rate of 5 years. Conventional cancer treatments including surgery, radiation, chemotherapy or combinations of these show little effect on this disease. Several proteins have been proved critical to the development and the prog...

journal_title：Chinese medical journal

authors： Zhou JH,Cheng HY,Yu ZQ,He DW,Pan Z,Yang DT

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The GlideScope videolaryngoscope (GSVL) has been shown to have no special advantage over the Macintosh direct laryngoscope (MDL) in attenuating the circulatory responses to orotracheal intubation, but no study has compared the circulatory responses to nasotracheal intubation (NTI) using the two devices. This...

journal_title：Chinese medical journal

authors： Xue FS,Li XY,Liu QJ,Liu HP,Yang QY,Xu YC,Liao X,Liu Y

更新日期：2008-07-20 00:00:00

abstract：BACKGROUND:This prospective, randomized, controlled study was designed to investigate the effects of a diabetes specific formula (Diason low energy: 313.8 kJ/100 ml), compared with a standard formula, on insulin sensitivity, serum C peptide, serum lipids and free fatty acid (FFA) in type 2 diabetics. METHODS:In total ...

journal_title：Chinese medical journal

authors： Li YX,Zeng JB,Yu K,Sun Q,Liu QY,Qin W,Zhang Q,Yu JC,Wang H

更新日期：2008-04-20 00:00:00

abstract：BACKGROUND:HIV-1 infected and immune-activated macrophages and microglia secrete neurotoxins, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), which play major role in the neuronal death. It has been shown that different HIV-1 variants have varying abilities to elicit secretion of TNF-α by peripheral...

journal_title：Chinese medical journal

authors： Yan YF,Wang ZY,Pu SS,Wen HL,Huang T,Song YY,Xu HZ,Zhao L

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Circumferential pulmonary vein isolation (CPVI), as the basal ablation strategy for treating atrial fibrillation (AF), not only isolates the connection between the left atrium (LA) and the pulmonary veins (PVs), but also induces extensive atrial endocardia damage. This could have an effect on the sinus pulse...

journal_title：Chinese medical journal

authors： Zhao L,Jiang WF,Zhou L,Liu X

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Peripheral nerve injury causes a high rate of disability and a huge economic burden, and is currently one of the serious health problems in the world. The use of nerve grafts plays a vital role in repairing nerve defects. Acellular nerve grafts have been widely used in many experimental models as a periphera...

journal_title：Chinese medical journal

authors： Ma XL,Sun XL,Yang Z,Li XL,Ma JX,Zhang Y,Yuan ZZ

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The incidence of vancomycin-resistant enterococci (VRE) appeared to be increasing in China, but very few nosocomial outbreaks have been reported. Our hospital had experienced an outbreak of VRE since March 2008 to March 2009. The objective of this study was to analyze the molecular features of the isolates a...

journal_title：Chinese medical journal

authors： Xu HT,Tian R,Chen DK,Xiao F,Nie ZY,Hu YJ,Zhang XZ,Li JM

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of the combination of octreotide and aspirin on the growth of gastric cancer. METHODS:Proliferation of gastric cancer cell lines treated with octreotide or aspirin was determined by (3)H-thymidine incorporation. After xenografts of human gastric cancer were implanted orthotopically...

journal_title：Chinese medical journal

authors： Tang C,Wang C,Tang L

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Previous studies suggested that zinc level was related to a certain diabetic microvascular complication. However, the relationship between zinc level and all the microvascular complications in type 2 diabetic patients remains unknown. The purpose of this study was to analyze the relationship between zinc lev...

journal_title：Chinese medical journal

authors： Luo YY,Zhao J,Han XY,Zhou XH,Wu J,Ji LN

更新日期：2015-12-20 00:00:00

abstract：BACKGROUND:Atrial natriuretic peptide (ANP) and its natriuretic peptide receptors A (NPR-A) and C (NPR-C) are involved in the regulation of physiological and pathophysiological process of blood pressure. The present study aimed to determine the role of NPR-C in the development of salt-sensitive hypertension. METHODS:T...

journal_title：Chinese medical journal

authors： Zhu XL,Zhang T,Xu ZQ,Ma XC,Wang ZJ,Zou CW,Li JX,Jing HY

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor (HGF) treats ischemic disease by promoting arteriogenesis, however, its mechanism of action is not known. The notch signaling pathway plays an important role in neovascularization. The relationship between the proliferation and migration ability of artery endothelial cells and the Dl...

journal_title：Chinese medical journal

authors： Gao YF,Ha XQ,Lü TD,Han JP

更新日期：2011-01-01 00:00:00

abstract：:After cis-diamminedichloroplatinum ethylcellulose microcapsules (CDDPmc) and unencapsulated CDDP were infused into the hepatic arteries of New Zealand rabbits, both CDDP concentrations in the circulating blood and in hepatic tissue were measured at different time intervals. In the rabbits infused with CDDPmc, the CDDP...

journal_title：Chinese medical journal

authors： Wang Y,Wu MC,Zhang XH

更新日期：1992-02-01 00:00:00

abstract：OBJECTIVE:To study the histopathological changes of relevant internal organs of Macaca mulatta infected with Plasmodium knowlesi (P. knowlesi). METHODS:Histopathological examination of 3 monkeys who died of P. knowlesi infection, 2 P. knowlesi infected monkeys who died of treatment failure with artesunate suppository ...

journal_title：Chinese medical journal

authors： Chen L,Li G,Lu Y,Luo Z

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:As an X-linked recessive way, arginine vasopressin receptor 2 (AVPR2) gene mutation resulted in a hereditary disease - congenital nephrogenic diabetes insipidus (CNDI). We found a suspect clinical CNDI pedigree. In order to identify the genetic etiology, we performed the genetic analysis. METHODS:The clinic...

journal_title：Chinese medical journal

authors： Shen Y,Lai X,Xiao X,Li J,Yu R,Gao H,Zhang M

更新日期：2014-01-01 00:00:00