Abstract:
BACKGROUND:The GlideScope videolaryngoscope (GSVL) has been shown to have no special advantage over the Macintosh direct laryngoscope (MDL) in attenuating the circulatory responses to orotracheal intubation, but no study has compared the circulatory responses to nasotracheal intubation (NTI) using the two devices. This prospective randomized clinical study was designed to determine whether there was a clinically relevant difference between the circulatory responses to NTI with the GSVL and the MDL. METHODS:Seventy-six adult patients were randomly allocated equally to the GSVL group and the MDL group. After induction of anesthesia, NTI was performed. Non-invasive blood pressure (BP) and heart rate (HR) were recorded before induction (baseline values) and immediately before intubation (post-induction values), at intubation and every minute for a further five minutes. During the observation, times required to reach the maximum values of systolic BP (SBP) and HR, times required for recovery of SBP and HR to postinduction values and incidence of SBP and HR percent changes > 30% of baseline values were also noted. The product of HR and systolic BP, i.e. rate pressure product (RPP), and the areas under SBP and HR vs. time curves (AUC(SBP) and AUC(HR)) were calculated. RESULTS:The NTI with the GSVL resulted in significant increases in BP, HR and RPP compared to postinduction values, but these circulatory changes did not exceed baseline values. BPs at all measuring points, AUC(SBP), maximum values of BP and incidence of SBP percent increase > 30% of baseline value during the observation did not differ significantly between groups. However, HR and RPP at intubation and their maximum values, AUC(HR) and incidence of HR percent increase > 30% of baseline value were significantly higher in the MDL group than in the GSVL group. Times required for recovery of SBP and HR to postinduction values were significantly longer in the MDL group than in the GSVL group. CONCLUSIONS:The pressor response to NTI with the GSVL and the MDL was similar, but the tachycardiac response to NTI was lesser and of a shorter duration when using a GSVL than when using an MDL.
journal_name
Chin Med J (Engl)journal_title
Chinese medical journalauthors
Xue FS,Li XY,Liu QJ,Liu HP,Yang QY,Xu YC,Liao X,Liu Ysubject
Has Abstractpub_date
2008-07-20 00:00:00pages
1290-6issue
14eissn
0366-6999issn
2542-5641journal_volume
121pub_type
杂志文章,随机对照试验abstract:OBJECTIVE:To investigate molecular events of exocytosis in cultured human pheochromocytoma cells with stimulation. METHODS:The cultured pheochromocytoma cells prepared from human adrenal pheochromocytoma tumor were stimulated for the release of catecholamines by depolarization with the administration of 50 mmol/L KCl....
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
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abstract:OBJECTIVES:To study the status of cochlear mitochondrial DNA (mtDNA) and to determine the location of mtDNA deletion in aged mice. METHODS:We detected cochlear mtDNA in 2, 7 - 10 and 17 - 19 month old mice by nested polymerase chain reaction (PCR) and DNA sequencing. RESULTS:mtDNA3867bp deletions were found in the co...
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doi:
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pub_type: 杂志文章
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doi:
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journal_title:Chinese medical journal
pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章
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更新日期:2012-02-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:
更新日期:2013-01-01 00:00:00
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:10.4103/0366-6999.178961
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journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
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pub_type: 临床试验,杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Esophageal carcinoma is a common kind of malignant tumor and about 90% of which is esophageal squamous cell carcinoma (ESCC), and it has a high incidence in China. In recent years it has been argued that angiogenesis plays a key role in tumor growth and metastasis and it is a complex process influenced by ma...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:2008-05-20 00:00:00
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pub_type: 杂志文章
doi:
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pub_type: 杂志文章
doi:
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pub_type: 杂志文章
doi:
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pub_type: 杂志文章
doi:
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abstract:OBJECTIVE:To investigate the expressions of hypothalamic arginine vasopressin (AVP) mRNA, renal AVP V2 receptor mRNA, and AVP-dependent aquaporin-2 (AQP2) mRNA in rats with adriamycin-induced nephrotic syndrome. Effects of Chinese herb Astragalus membranaceus (AM) were also tested. METHODS:Sprague-Dawley rats with fou...
journal_title:Chinese medical journal
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract::[This corrects the article DOI: 10.4103/0366-6999.181956.]. ...
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pub_type: 杂志文章,已发布勘误
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更新日期:2016-07-20 00:00:00
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pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
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pub_type: 杂志文章
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