Expression of Total Vascular Endothelial Growth Factor and the Anti-angiogenic VEGF 165 b Isoform in the Vitreous of Patients with Retinopathy of Prematurity.

abstract：BACKGROUND:Sericin peptide (SP) has shown a powerful anti-oxidant property in a host of studies. The present study was designed to investigate the possible protective effects of SP against alcohol-induced gastric lesions in mice and to explore the potential mechanisms. METHODS:Animals were randomly divided into 5 grou...

journal_title：Chinese medical journal

authors： Li YG,Ji DF,Lin TB,Zhong S,Hu GY,Chen S

更新日期：2008-10-20 00:00:00

abstract：BACKGROUND:Cartilage injury has a very poor capacity for intrinsic regeneration. The cell-based treatment strategy for the cartilage repair using differentiated bone marrow mesenchymal stem cells (BMSCs) is, however, a promising approach to the chondral repair. This study was aimed to explore the chondrogenic potential...

journal_title：Chinese medical journal

authors： Li JW,Guo XL,He CL,Tuo YH,Wang Z,Wen J,Jin D

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To investigate all-trans retinoic acid (ATRA) and As2O3 which were found to be able to selectively induce differentiation and apoptosis in acute promyelocytic leukemia (APL) and recently became standard treatment for de novo or relapsed APL. The results of long-term follow up in 72 APL patients were presented...

journal_title：Chinese medical journal

authors： Hu J,Shen Z,Sun H,Wu W,Li X,Sun G,Wang Z

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:To investigate the histologic and histogenetic relationship between various types of rhabdomyosarcomas (RMS) and embryonal skeletal muscle (ESM) for further understanding of the histogenesis, classification and pattern of differentiation of RMS. METHODS:Fifty cases of variant types of RMS and 20 cases of ESM...

journal_title：Chinese medical journal

authors： Lai R,Tian Y,An J,Zhou MW,Zou G,Li W

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Acinetobacter baumannii is one of the main gram-negative bacilli in clinical practice. Nosocomial infections caused by multi-drug resistance Acinetobacter baumannii is very difficult to treat. This study was designed to investigate the antimicrobial resistance characteristics and four resistant gene expressi...

journal_title：Chinese medical journal

authors： Shi WF,Jiang JP,Mi ZH

更新日期：2005-01-20 00:00:00

abstract：OBJECTIVE:To evaluate the human neuroblastoma SH-SY5Y cell line as an in vitro model of dopaminergic (DAergic) neurons for Parkinson's disease (PD) research and to determine the effect of differentiation on this cell model. DATA SOURCES:The data of this review were selected from the original reports and reviews relate...

journal_title：Chinese medical journal

authors： Xie HR,Hu LS,Li GY

更新日期：2010-04-20 00:00:00

abstract：BACKGROUND:A satisfactory animal model of breast cancer metastasizing to bone is unavailable. In this study, we used human breast cancer stem-like cells and human bone to build a novel "human-source" model of human breast cancer skeletal metastasis. METHODS:Human breast cancer stem-like cells, the CD44+/CD24-/lower su...

journal_title：Chinese medical journal

authors： Ling LJ,Wang S,Liu XA,Shen EC,Ding Q,Lu C,Xu J,Cao QH,Zhu HQ,Wang F

更新日期：2008-10-20 00:00:00

abstract：BACKGROUND:Angiopoietin-2 (Ang-2) is one of the critical regulators of tumor angiogenesis. Studies have shown a significant correlation of Ang-2 expression to tumor invasion and metastasis in various human cancers, but little is known about the serum Ang-2 (sAng-2) levels in esophageal squamous cell cancer (ESCC) and i...

journal_title：Chinese medical journal

authors： Zhou YZ,Fang XQ,Li H,Diao YT,Yang YF,Zhao DL,Wu K,Li HQ

更新日期：2007-07-20 00:00:00

abstract：OBJECTIVE:To develop a diagnostic framework that would help defining clinical problems by the expanded understanding with traditional Chinese medicine (C Med) and western medicine (W Med). METHODS:The basic attributes of diagnosis and the use of diagnostic techniques of W Med and C Med are reviewed. Some of the variou...

journal_title：Chinese medical journal

authors： Yu EC

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:We conducted a prospective, multicenter investigation of incidence, management and outcome of neonatal acute respiratory disorders (NARD), and evaluated related perinatal risk factors and efficacy of respiratory therapies in neonatal intensive care units (NICUs) in a Chinese neonatal network. METHODS:Data w...

journal_title：Chinese medical journal

authors： Qian LL,Liu CQ,Guo YX,Jiang YJ,Ni LM,Xia SW,Liu XH,Zhuang WZ,Xiao ZH,Wang SN,Zhou XY,Sun B,Chinese Collaborative Study Group for Neonatal Respiratory Diseases.

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Surgical interventions are the main treatment for primary congenital glaucoma (PCG). This study aimed to compare the efficacy and safety between viscocanalostomy and mitomycin C (MMC)-trabeculectomy in patients with PCG. METHODS:A total number of 43 patients with PCG who underwent either viscocanalostomy (g...

journal_title：Chinese medical journal

authors： Chen Q,Yu Y,Sun H,Zong Y,Yuan ZL

更新日期：2013-01-01 00:00:00

abstract：Objective:Since the advent of induced pluripotent stem cell (iPSC) technology a decade ago, enormous progress has been made in stem cell biology and regenerative medicine. Human iPSCs have been widely used for disease modeling, drug discovery, and cell therapy development. In this review, we discuss the progress in app...

journal_title：Chinese medical journal

authors： Wang F,Kong J,Cui YY,Liu P,Wen JY

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:The medium-to-long-term use of antimuscarinics alone or in combination with an α-blocker in men with an enlarged prostate is still controversial. This double-blind, placebo-controlled, randomized clinical trial aimed to investigate the efficacy and safety of medium-to-long-term use of tolterodine extended re...

journal_title：Chinese medical journal

authors： Cai JL,Zhou Z,Yang Y,Yan YF,Jing S,Na YQ

更新日期：2016-12-20 00:00:00

abstract：OBJECTIVE:To investigate molecular events of exocytosis in cultured human pheochromocytoma cells with stimulation. METHODS:The cultured pheochromocytoma cells prepared from human adrenal pheochromocytoma tumor were stimulated for the release of catecholamines by depolarization with the administration of 50 mmol/L KCl....

journal_title：Chinese medical journal

authors： Lee YS,Chou YY

更新日期：1998-04-01 00:00:00

abstract：:Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational leve...

journal_title：Chinese medical journal

authors： Song JK,Yin SY,Li W,Li XD,Luo Y,Luo Y,Xing M,Li B,Kuai L

更新日期：2020-12-14 00:00:00

abstract：:The vascular pedicled periosteum was used in 11 cases in our hospital for the treatment of femoral neck fracture with good result. The follow-up period ranged from 2 to 6 years, with an average of 4 years. Animal experiment was made to elucidate the repairing process. It demonstrated that the pedicled periosteum playe...

journal_title：Chinese medical journal

authors： Zhu SX,Shen YN,Lu SB,Zhang BX,Wang JF

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Ketanserin (KT), a selective serotonin (5-HT) 2-receptor antagonist, reduces peripheral blood pressure by blocking the activation of peripheral 5-HT receptors. In this study electrophysiological method was used to investigate the effect of KT and potassium ion on Kv1.3 potassium channels and explore the role...

journal_title：Chinese medical journal

authors： Liang ZT,Wang XP,Zeng QT,Liao YH,Zou AR,Li L,Tu DN

更新日期：2008-12-20 00:00:00

abstract：BACKGROUND:Blood glucose control is closely related to type 2 diabetes mellitus (T2DM) prognosis. This multicenter study aimed to investigate blood glucose control among patients with insulin-treated T2DM in North China and explore the application value of combining an elastic network (EN) with a machine-learning algor...

journal_title：Chinese medical journal

authors： Wang J,Wang MY,Wang H,Liu HW,Lu R,Duan TQ,Li CP,Cui Z,Liu YY,Lyu YJ,Ma J

更新日期：2020-01-05 00:00:00

abstract：BACKGROUND:The primary ovarian sarcoma is a very rare malignancy. The objective of this study was to further investigate the clinicopathologic features and outcome in patients with primary sarcoma of the ovary. METHODS:Between 1988 and 2007, 24 patients with primary ovarian sarcoma who underwent treatment at Peking Un...

journal_title：Chinese medical journal

authors： Dai Y,Shen K,Lang JH,Huang HF,Pan LY,Wu M,Yang JX,Zhong DR

更新日期：2011-05-01 00:00:00

abstract：:Intraoperative coronary venography was performed in 24 patients before and after portal-azygos disconnection for portal hypertension. Before the procedure the portal vein was found to be communicated with cardial and esophageal veins by two pathways, i,e., from the esophageal and gastric branches of the coronary vein ...

journal_title：Chinese medical journal

authors： Zou ZS,Li JS,Li N,Liu FK

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Many recipients of implantable cardiac electronic devices have atrial fibrillation (AF) occurrences after device implantation, even if there is no previous history of AF, and some of the episodes are asymptomatic. The purpose of this study was to evaluate trends in AF burden following early AF detection in p...

journal_title：Chinese medical journal

authors： Chen KP,Dai Y,Hua W,Yang JF,Li K,Liang ZG,Shen FR,Chen SL,Su YG,Ding YS,Zhang S

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The chronic obstructive pulmonary disease assessment test (CAT) is an easy to use health-related quality of life questionnaire, the modified Medical Research Council (mMRC) dyspnea scale is a classic dyspnea scale which is widely used, while the correlation between them is still not clear. This study investi...

journal_title：Chinese medical journal

authors： Zhou QT,Mei JJ,He B,Huang SG,Shi Y,Wen FQ,Zhao MW

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Interferon-gamma release assay (IGRA) has been used in latent tuberculosis (TB) infection and TB diagnosis, but the results from different high TB-endemic countries are different. The aim of this study was to investigate the value of IGRA in the diagnosis of active pulmonary TB (PTB) in China. METHODS:We co...

journal_title：Chinese medical journal

authors： Kang WL,Wang GR,Wu MY,Yang KY,Er-Tai A,Wu SC,Geng SJ,Li ZH,Li MW,Li L,Tang SJ

更新日期：2018-02-05 00:00:00

abstract：BACKGROUND:Glaucoma is mainly characterized by the loss of retinal ganglion cells. Ciliary neurotrophic factor (CNTF) is believed to stimulate the regeneration of axons of retinal ganglion cells. The objective of our study was to detect the expression of CNTF in the retina of a rat glaucoma model with increased intraoc...

journal_title：Chinese medical journal

authors： Wu Q,Zhang M,Song BW,Lu B,Hu P

更新日期：2007-10-20 00:00:00

abstract：OBJECTIVES:To study the interrelation between nitric oxide (NO) and endothelin-1 (ET1) in experimental acute hypoxic rats, and to evaluate the mechanism of acute hypoxic pulmonary hypertension affected by NO and ET1 and its intervention. METHODS:Nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase histochemi...

journal_title：Chinese medical journal

authors： Wang Y,Zhang L,Shen W,Chen L,Fan S

更新日期：1999-04-01 00:00:00

abstract：:Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. The heart is one of the most important oxygen delivery organs, and dysfunction significantly increases the mortality of the body. Hence, the heart has been studied in sepsis for over half a century. However, th...

journal_title：Chinese medical journal

authors： Wang J,Wang XT,Liu DW,Zhang HM,Su LX

更新日期：2020-09-20 00:00:00

abstract：OBJECTIVE:To detect the virus in the feces and sera of patients in an outbreak of enterically transmitted non-A, non-E hepatitis, and this review covers the epidemiologic features and experimental infection of this novel virus. DATA SOURCES:Data sources come from our own work on this subject, published and unpublished...

journal_title：Chinese medical journal

authors： Luo K,Zhang L

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Little information is available to guide treatment strategies regarding patients with unexpected positive cultures (UPC), including Propionibacterium acnes (PA), without overt signs of infection in revision shoulder arthroplasty (RSA). The purpose of our study was to analyze the prevalence, clinical meaning, ...

journal_title：Chinese medical journal

authors： Kim SJ,Kim JH

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Airway mucus hypersecretion is an important pathophysiological feature of chronic obstructive pulmonary disease, which is closely associated with cigarette smoking. However, the signal transduction pathway from the cell surface to the nucleus through which cigarette smoke causes upregulation of mucin gene ex...

journal_title：Chinese medical journal

authors： Xiao J,Wang K,Feng YL,Chen XR,Xu D,Zhang MK

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Peripheral nerve injury causes a high rate of disability and a huge economic burden, and is currently one of the serious health problems in the world. The use of nerve grafts plays a vital role in repairing nerve defects. Acellular nerve grafts have been widely used in many experimental models as a periphera...

journal_title：Chinese medical journal

authors： Ma XL,Sun XL,Yang Z,Li XL,Ma JX,Zhang Y,Yuan ZZ

更新日期：2011-12-01 00:00:00