Abstract：
:We investigated the change in chlortetracycline resistance in 360 Escherichia coli strains separated from the feces of piglets fed fermented liquid feed (FLF) in comparison with those fed dry feed (control). The total amount of lactic acid bacteria in feces was 8.77 x 10(8) CFU/g DM at weaning, which increased to 1.23 x 10(12) CFU/g DM (FLF) at 28 days after weaning (P<0.001). As a result of the antibiotic susceptibility test, almost all isolates were chlortetracycline-resistant (CTCR) until 14 days after weaning both in the FLF and control groups. At 28 days, the CTCR E. coli decreased to 22.2% in the FLF group, while the proportion of resistant bacteria was 88.9% in the control group. In addition, as a result of the gene analysis, it was clarified that there is a relation between the decrease in the minimum inhibitory concentration values and the possession rate of the tetracycline-resistance gene tet(A), tet(B) and tet(D). These results show that FLF caused an increase in the number of lactic acid bacteria in the intestines, and suggested that the feeding of FLF can possibly reduce antibiotic-resistance bacteria.
journal_name
Anaerobejournal_title
Anaerobeauthors
Kobashi Y,Ohmori H,Tajima K,Kawashima T,Uchiyama Hdoi
10.1016/j.anaerobe.2008.07.001subject
Has Abstractpub_date
2008-10-01 00:00:00pages
201-4issue
4eissn
1075-9964issn
1095-8274pii
S1075-9964(08)00077-2journal_volume
14pub_type
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