Involvement of Ad4BP/SF-1, DAX-1, and COUP-TFII transcription factor on steroid production and luteinization in ovarian theca cells.

abstract：:Chemotherapy remains the core of anticancer treatment. However, despite the tremendous strides made in the development of targeted anticancer therapies, emergence of resistance to chemotherapeutic drugs is still a major obstacle in the successful management of resistant tumors. Therefore, profound investigation into t...

journal_title：Molecular and cellular biochemistry

authors： Peng L,Zhu H,Wang J,Sui H,Zhang H,Jin C,Li L,Xu T,Miao R

更新日期：2015-07-01 00:00:00

abstract：:Early responses of lungs to a single radiation dose of 30 Gy were marked by an inflammatory reaction and the onset of pneumonitis within 4 weeks following hemithorax radiation in the rat. Superoxide dismutase reduced the severity of radiation lesions in lungs. ...

journal_title：Molecular and cellular biochemistry

authors： Malaker K,Das RM

更新日期：1988-12-01 00:00:00

abstract：:Recently there has been a moderate resurgence in the use of flax-seed in a variety of ways including bread. The scientific basis of its use is very limited. There is some claim for beneficial effects in cancer and lupus nephritis. These claims could be due to its ability to scavenge oxygen radicals. However, its antio...

journal_title：Molecular and cellular biochemistry

authors： Prasad K

更新日期：1997-03-01 00:00:00

abstract：:Ribosomal 60S subunits active in polyphenylalanine synthesis can be reconstituted from core particles lacking 20-40% of the total protein. These core particles were obtained by treatment of yeast 60S subunits with dimethylmaleic anhydride, a reagent for protein amino groups. Upon reconstitution a complementary amount ...

journal_title：Molecular and cellular biochemistry

authors： Vioque A,Palacián E

更新日期：1985-02-01 00:00:00

abstract：:The ability of ANP to inhibit the hydrolysis of phosphoinositides was examined in [3H] myoinositol-labeled intact murine Leydig tumor (MA-10) cells. Arginine vasopressin (AVP) stimulated the formation of inositol monophosphate (IP1), inositol bisphosphate (IP2), and inositol trisphosphate (IP3) both in a time-and dose...

journal_title：Molecular and cellular biochemistry

authors： Khurana ML,Pandey KN

更新日期：1996-05-24 00:00:00

abstract：:This comparative study investigates the relationship between sarcoplasmic reticulum (SR) calcium(Ca2+)-ATPase transport activity and phospholamban (PLB) phosphorylation in whole cardiac homogenates of spontaneously hypertensive rats (SHR) and their parent, normotensive Wistar Kyoto (WKY) strain during early postnatal ...

journal_title：Molecular and cellular biochemistry

authors： Freestone N,Singh J,Krause EG,Vetter R

更新日期：1996-10-01 00:00:00

abstract：:In this study, we aimed to study the role of miRNAs in intrauterine adhesion (IUA) disease. An IUA cell model was constructed by TGF-β1. Smad3 inhibitor (SIS3) can inhibit the Smad3 signaling pathway and affect the role of TGF-β1; thus, it was used to identify the role of Smad3 and related miRNAs in IUA. Cell number s...

journal_title：Molecular and cellular biochemistry

authors： Liu S,Huang X,Liu Y,Song D,Xiao Y

更新日期：2020-07-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are two hormones produced and secreted by the heart to control blood pressure, body fluid homeostasis and electrolyte balance. Each peptide binds to a common family of 3 receptors (GC-A, GC-B and C-receptor) with varying degrees of affinity. The pro...

journal_title：Molecular and cellular biochemistry

authors： Tse MY,Watson JD,Sarda IR,Flynn TG,Pang SC

更新日期：2001-03-01 00:00:00

abstract：:The present study was designed to evaluate the in vitro and in vivo ameliorative antioxidant potential of secoisolariciresinol diglucoside (SDG). In vitro antioxidant activity of synthetic SDG was carried out using DPPH, reducing power potency, and DNA protection assays. Wistar albino rats weighing 180-220 g were used...

journal_title：Molecular and cellular biochemistry

authors： Moree SS,Rajesha J

更新日期：2013-01-01 00:00:00

abstract：:Cardiovascular diseases involve critical mechanisms including impaired nitric oxide (NO) levels and abnormal matrix metalloproteinase (MMP) activity. While NO downregulates MMP expression in some cell types, no previous study has examined whether NO downregulates MMP levels in endothelial cells. We hypothesized that N...

journal_title：Molecular and cellular biochemistry

authors： Meschiari CA,Izidoro-Toledo T,Gerlach RF,Tanus-Santos JE

更新日期：2013-06-01 00:00:00

abstract：:Female rats at weaning (30 days age) were maintained on vitamin E-deficient diet for 70 days. The vitamin E-deficient and control animals were sacrificed on 100 days of age. To study recovery a group of animals were supplemented with normal diet for last 25 days after initial 45 days of deficient diet or vice versa. T...

journal_title：Molecular and cellular biochemistry

authors： Das P,Chowdhury M

更新日期：1999-08-01 00:00:00

abstract：:The rat uterine secretory enzyme glycerylphosphorylcholine (GPC) diesterase (EC 3.1.4.2) had been purified and characterized previously with respect to its mol. wt., size, amino acid, carbohydrate composition and estrogen inducible properties. This enzyme is observed to have exclusive specificity for GPC and exhibits ...

journal_title：Molecular and cellular biochemistry

authors： Mitra J,Chowdhury M

更新日期：1994-10-26 00:00:00

abstract：:Administration of nifedipine to mice over a period of six months caused a significant (p < 0.05) decrease in neutrophilic functions viz superoxide generation, coupled to NADPH oxidase activity as well as NADPH production by HMP shunt. Properties like chemotaxis and phagocytosis showed a similar decrease. From this stu...

journal_title：Molecular and cellular biochemistry

authors： Kaul N,Andrabi KI,Ganguly NK,Wahi PL

更新日期：1993-03-10 00:00:00

abstract：:Acyl-CoA: lysolecithin and lysolecithin: lysolecithin acyltransferases, as well as acyl-CoA hydrolase are important enzymes in lung lipid metabolism. They use amphiphylic lipids as substrates and differ in subcellular localization. In this sense, lipid-protein interactions can be an essential factor in their activity....

journal_title：Molecular and cellular biochemistry

authors： Pérez-Gil J,Estrada P,Acebal C,Arche R

更新日期：1990-05-10 00:00:00

abstract：:The aim of this study was to investigate the interrelationship between the mitochondrial phospholipid cardiolipin (CL), mitochondrial respiration and morphology in dependence on hypoxia/reoxygenation and Ca(2+). Therefore, we subjected rat liver mitochondria to hypoxia/reoxygenation at different extramitochondrial Ca(...

journal_title：Molecular and cellular biochemistry

authors： Martens JC,Keilhoff G,Gardemann A,Schild L

更新日期：2014-09-01 00:00:00

abstract：:This study examined the role of the protein kinase C (PKC) signalling pathway in the regulation of expression of human complement factor I (CFI) gene. The production of CFI by Hep G2 cells was enhanced in a dose- and time-dependent fashion by 12-O-tetradecanoyl-1,2-phorbol 13-acetate (TPA), a potent PKC activator. 4Al...

journal_title：Molecular and cellular biochemistry

authors： Minta J,Fung M

更新日期：1999-11-01 00:00:00

abstract：:Evidence suggests that functional atrial natriuretic peptide (ANP) receptors occur in surface gastric mucosal epithelial cells. To evaluate functional aspects of ANP in a model of these cells we examined the expression of natriuretic peptide receptors (NPR) subtypes A and C in the non-transformed rat gastric mucosal e...

journal_title：Molecular and cellular biochemistry

authors： Gower WR Jr,Carter GM,McAfee Q,Solivan SM

更新日期：2006-12-01 00:00:00

abstract：:We measured the relative sliding velocity of cardiomyopathic hamster cardiac myosin on actin cables by using an in vitro motility assay system. We also investigated the relationship between the velocity and both myosin isozyme content and ATPase activity. Cardiac myosin was obtained from cardiomyopathic hamsters (BIO ...

journal_title：Molecular and cellular biochemistry

authors： Yamashita H,Sugiura S,Sata M,Serizawa T,Iizuka M,Shimmen T,Momomura S

更新日期：1993-02-17 00:00:00

abstract：:Recent studies suggest JAK2 signaling may be a therapeutic target for treatment of gastric cancer (GC). However, the exact roles of JAK2 in gastric carcinogenesis are not very clear. Here, we have targeted JAK2 to be silenced by shRNA and investigated the biological functions and related mechanisms of JAK2 in GC cell ...

journal_title：Molecular and cellular biochemistry

authors： Qian C,Yao J,Wang J,Wang L,Xue M,Zhou T,Liu W,Si J

更新日期：2014-02-01 00:00:00

abstract：:Gastric pathology is a common complication in diabetes mellitus. The aim of the study was to evaluate the functions and morphological changes of the parietal cells of the rat stomach after streptozotocin-induced diabetes. Diabetes mellitus was induced in Wistar rats by a single intraperitoneal injection of streptozoto...

journal_title：Molecular and cellular biochemistry

authors： Bastaki SM,Adeghate E,Chandranath IS,Amir N,Tariq S,Hameed RS,Adem A

更新日期：2010-08-01 00:00:00

abstract：:Protein kinase CK2 is a highly conserved and ubiquitous serine-threonine kinase. It is a tetrameric enzyme that is made up of two regulatory CK2beta subunits and two catalytic subunits, either CK2alpha/CK2alpha, CK2alpha/CK2alpha', or CK2alpha'/CK2alpha'. Although the two catalytic subunits diverge in their C termini,...

journal_title：Molecular and cellular biochemistry

authors： Seldin DC,Lou DY,Toselli P,Landesman-Bollag E,Dominguez I

更新日期：2008-09-01 00:00:00

abstract：:Hyperhomocysteinemia (HHcy) is an independent risk factor of cardiovascular disease, but the mechanisms of tissue injury are poorly understood. In the present study, we investigated the effect of HHcy on rat heart function, activities electron transport chain (ETC) complexes, mitochondrial protein expression, and prot...

journal_title：Molecular and cellular biochemistry

authors： Timkova V,Tatarkova Z,Lehotsky J,Racay P,Dobrota D,Kaplan P

更新日期：2016-01-01 00:00:00

abstract：:Glucocorticoid hormones (GCH) are anti-inflammatory and immunosuppressive agents that inhibit T-cell growth and activation. Since the T-cell receptor (TCR)/CD3 complex mediates T-lymphocyte activation, we studied the effect of in vitro dexamethasone (DEX), a synthetic GCH, on TCR/CD3 expression. DEX-treatment of a hyb...

journal_title：Molecular and cellular biochemistry

authors： Migliorati G,Bartoli A,Nocentini G,Ronchetti S,Moraca R,Riccardi C

更新日期：1997-02-01 00:00:00

abstract：:Vasculogenesis was long considered to be a mechanism of blood vessel formation limited to the embryo, and not used in adult vascular repair. Similarly, myocardial proliferation was generally thought to cease in the adult. Yet there is an extensive older literature suggesting that blood might be a source of adult angio...

journal_title：Molecular and cellular biochemistry

authors： Schatteman GC

更新日期：2004-09-01 00:00:00

abstract：:Partial outlet obstruction of the rabbit urinary bladder results, initially, in a rapid increase in bladder mass and remodeling of the bladder wall. Previously, it was shown that this response was characterized by serosal growth (thickening) which was apparent after 1 day of obstruction, before any visible vasculariza...

journal_title：Molecular and cellular biochemistry

authors： Chichester P,Schröder A,Horan P,Levin RM

更新日期：2001-10-01 00:00:00

abstract：:The energy metabolism of rat thymus cells has been investigated using preparations of isolated cells obtained by mechanical treatment of whole organs. The addition of glycolytic substrates such as glucose, pyruvate and lactate stimulates the endogenous respiration of these cells by 50%. On the other hand, succinate, g...

journal_title：Molecular and cellular biochemistry

authors： Cittadini A,Bossi D,Longhi G,Terranova T

更新日期：1975-07-31 00:00:00

abstract：:The native form of phospholamban is not known and it is presently under debate whether this protein exists as a monomer or an oligomer in cardiac sarcoplasmic reticulum. The currently accepted model for phospholamban is pentameric, based primarily on its behavior in SDS-polyacrylamide gel electrophoresis. In this stud...

journal_title：Molecular and cellular biochemistry

authors： Harrer JM,Kranias EG

更新日期：1994-11-23 00:00:00

abstract：:Glomerular mesangial cells play an important role in the development of glomerulosclerosis. Mesangial cell apoptosis has been shown to be involved in different stages of development of glomerulonephritis. The aim of the present study was to evaluate the effect of inhibition of serine/threonine phosphatases by okadaic ...

journal_title：Molecular and cellular biochemistry

authors： Parameswaran N,Spielman WS,Brooks DP,Nambi P

更新日期：2004-05-01 00:00:00

abstract：:The development and growth of the prostate gland depends on androgen stimulation. Dihydrotestosterone (DHT) is the primary androgen responsible for prostate development and also for the pathogenesis of benign prostatic hyperplasia (BPH). The incidence of prostate cancer (PCa) and benign prostatic hypertrophy (BPH) con...

journal_title：Molecular and cellular biochemistry

authors： Torres JM,Gómez-Capilla JA,Ruiz E,Ortega E

更新日期：2003-08-01 00:00:00

abstract：:The incorporation of radiolabeled arachidonic acid (3[H]-AA) in normoxic cardiomyocytes (MC), cardiac endothelial cells (EC) and fibroblast-like cells (FL) isolated from adult rat heart was studied. Deposition of 3[H]-AA in the cellular lipid pool was assessed with biochemical and autoradiographic techniques. Extracti...

journal_title：Molecular and cellular biochemistry

authors： Linssen MC,Willemsen PH,Heijnen VV,van der Vusse GJ

更新日期：1992-10-21 00:00:00