Abstract：
OBJECTIVE:To assess the use and effectiveness of IVF in a cohort of women undergoing surgery for endometriosis. DESIGN:Cohort study. SETTING:University hospital. PATIENT(S):Four hundred thirty-eight patients who attempted to become pregnant after conservative surgery for endometriosis. INTERVENTION(S):Interview. MAIN OUTCOME MEASURE(S):Pregnancy and IVF use. RESULT(S):One hundred ninety-four women conceived in vivo (44%). One hundred twenty-four women did not undergo IVF despite their infertility status (51% of the group of women who failed to conceive in vivo). One hundred thirty-nine women underwent at least one IVF attempt. The cumulative rate of IVF use at 36 months of infertility was 33%. The live-birth/ongoing pregnancy rate per started cycle and per patient was 10% and 20%, respectively. CONCLUSION(S):In a large tertiary care and referral center, IVF played only a minor role in the treatment of endometriosis-associated infertility.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Somigliana E,Daguati R,Vercellini P,Barbara G,Benaglia L,Crosignani PGdoi
10.1016/j.fertnstert.2008.02.004subject
Has Abstractpub_date
2009-05-01 00:00:00pages
1775-9issue
5eissn
0015-0282issn
1556-5653pii
S0015-0282(08)00244-6journal_volume
91pub_type
杂志文章abstract：:One hundred and two women with insulin-resistant polycystic ovary syndrome were randomized to treatment with a vitamin B preparation, metformin, or both, in conjunction with standard infertility treatment. Plasma homocysteine levels were significantly reduced by both B vitamins and metformin, but to a greater degree b...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2006.11.071
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVE:To elucidate reinitiation factors in human spermatozoa preserved in the electrolyte-free solution at 4 degrees C. SETTING:Andrology laboratory of our hospital. PATIENTS:Semen samples were obtained from patients attending our infertility clinic. INTERVENTIONS:Ejaculated sperm were centrifuged and washed usi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)58341-1
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVE:Platelet-activating factor-acether (PAF-acether) presence was investigated in 27 human follicular fluids (FFs). DESIGN:Aggregation of washed rabbit platelets was used to measure PAF-acether. Data were compared using Student's t-test. SETTING:Follicular fluids came from the in vitro fertilization program at ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54417-3
更新日期：1991-07-01 00:00:00
abstract：OBJECTIVE:To determine whether there is an association between abnormal semen parameters and occupational exposures to organic solvents, metals, and pesticides. DESIGN:Case-control study using three case groups based on different cutoff values for semen parameters and one standard reference group. SETTING:University ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00542-1
更新日期：1999-04-01 00:00:00
abstract：:In the human, hyperprolactinemia may interfere with fertility. To find out whether or not prolactin (PRL) can act directly on human ovarian tissues, in vitro studies involving specific binding of human PRL to various human ovarian elements were carried out. Human PRL was isolated from amniotic fluid, and its intact mo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)46456-3
更新日期：1982-08-01 00:00:00
abstract：OBJECTIVE:The aim of the International Endogene Study is to discover genes that influence susceptibility to endometriosis. DESIGN:The study brings together two research groups based in Australia and the United Kingdom that independently have been collecting families for linkage analysis and candidate gene studies. Bot...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)03341-1
更新日期：2002-10-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy of tibolone add-back therapy with Goserelin treatment of uterine fibroids. DESIGN:Randomized placebo-controlled study. SETTING:Gynecology department of an inner-city teaching hospital. PATIENT(S):Seventy-five women of reproductive age with uterine fibroids. INTERVENTION(S):All women...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2007.02.064
更新日期：2008-02-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence of idiopathic hirsutism among a population of consecutive hirsute patients. DESIGN:Prospective cohort study. SETTING:University-based clinic. PATIENT(S):Premenopausal women with a complaint of hirsutism who were not receiving hormonal therapy. INTERVENTION(S):Evaluations for to...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00141-1
更新日期：1998-08-01 00:00:00
abstract：OBJECTIVE:To examine the effect of high doses of gonadotropins on IVF outcome in normal (intermediate) responders. DESIGN:Retrospective analysis of patients undergoing IVF therapy from 1990 to 1994 at our institution. SETTING:Academic tertiary center. PATIENTS:A homogeneous group of women that consisted of intermedi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)57621-3
更新日期：1995-06-01 00:00:00
abstract：:A study has been carried out, by means of an indole microchemical technique, of the DNA content of spermatozoa from a group of 13 normal subjects and 13 patients affected by infertility, characterized by oligospermia with a clinical, hormonal, and testicular picture peculiar to "idiopathic spermatidic arrest." The DNA...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)41590-6
更新日期：1976-01-01 00:00:00
abstract：OBJECTIVE:The response to subcutaneous (SC) gonadotropin replacement therapy, using human chorionic gonadotropin (hCG) and human menopausal gonadotropin (hMG) or hCG alone, was evaluated in male hypothalamic hypogonadism. DESIGN:Sixteen patients with hypothalamic hypogonadism were treated with gonadotropins for induct...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54493-8
更新日期：1991-08-01 00:00:00
abstract：OBJECTIVE:To investigate the molecular mechanism for declining sperm motility in older men. DESIGN:Retrospective and prospective study. SETTING:University-based andrology unit. PATIENT(S):Semen was collected from 2,111 patients and sperm donors. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Age, sperm concentratio...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.05.020
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVE:To investigate the relationship between growth hormone (GH) and luteal function. DESIGN:In vivo comparative and in vitro culture studies. SETTING:University hospital. PATIENT(S):Eighteen women who were interested in becoming pregnant and visited our clinic voluntarily participated in the study for urinary ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.07.1304
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To determine if endometrial tissue specific complement (C) activation occurs in patients with endometriosis. DESIGN:Prospective. SETTING:University of Oklahoma Health Sciences Center, a tertiary care referral center. PATIENTS:Twenty-six women, 9 with endometriosis and 17 without endometriosis. INTERVENTIO...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:A new sperm isolation technique was studied in conjunction with the short-term freeze preservation of human spermatozoa. The isolation procedure yielded subpopulations of spermatozoa with very high percentage motility and progressive motility score, and which were virtually free of seminal debris. For 24 semen samples...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42196-5
更新日期：1976-11-01 00:00:00
abstract：:In the United States, approximately 650,000 women of reproductive age undergo tubal sterilization each year and some of these women later have hysterectomies. Little is known about risk factors for having hysterectomy after tubal sterilization. For examination of this issue, we analyzed data from the Collaborative Rev...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48974-0
更新日期：1985-11-01 00:00:00
abstract：OBJECTIVE:To examine gonadal protective properties of granulocyte colony-stimulating factor (G-CSF) alone or in combination with stem cell factor (SCF) in female mice treated with high-dose alkylating chemotherapy. DESIGN:Experimental laboratory animal study. SETTING:Tertiary care academic hospital and research insti...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.01.135
更新日期：2013-06-01 00:00:00
abstract：OBJECTIVE:To confirm the advantages of goserelin prior to endometrial ablation for the treatment of dysfunctional uterine bleeding. DESIGN:Multicenter, prospective, randomized, double-blind study. PATIENT(S):Cycling premenopausal women with dysfunctional uterine bleeding. TREATMENT:Patients were randomized to gosere...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：1997-07-01 00:00:00
abstract：:Although previous large series have reported that from 0.3% to 1.3% of patients undergoing hysterosalpingography (HSG) develop infectious morbidity, our impression was that the incidence was higher among our patients. Therefore the records of 448 consecutive healthy women who underwent HSG were examined. Within 24 hou...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)44712-6
更新日期：1980-05-01 00:00:00
abstract：:We hypothesized that diminished endothelin 1 (ET-1) expression at the spermatic vein wall level might be responsible for the development of varicocele. However, immunohistochemical evaluation of spermatic and control vein samples from 55 patients with varicocele showed overexpression of ET-1 and its receptors ETA and ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.04.062
更新日期：2011-06-30 00:00:00
abstract：OBJECTIVE:To investigate differentially expressed genes in epithelial and stromal cells of eutopic endometrium from patients with deep endometriosis and women with normal pelvic cavities using laser capture microdissection and complementary DNA microarrays. DESIGN:Prospective study. SETTING:University hospital. PATI...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.04.041
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVE:To search for mutations in the coding exons of the follistatin gene of women diagnosed with polycystic ovary syndrome (PCOS). DESIGN:Controlled clinical study. SETTING:Tertiary institutional hospital. PATIENT(S):Thirty-four women diagnosed with PCOS and 15 healthy control women. INTERVENTION(S):Whole bloo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)01697-1
更新日期：2001-05-01 00:00:00
abstract：OBJECTIVE:To characterize the variability of hormonal profiles during the luteal phase in normal cycles. DESIGN:Observational study. SETTING:Not applicable. PATIENT(S):Ninety-nine women contributing 266 menstrual cycles. INTERVENTION(S):The women collected first morning urine samples that were analyzed for estrone-...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2017.05.012
更新日期：2017-07-01 00:00:00
abstract：:Bilateral hypogastric artery ligation followed by dilatation and evacuation under laparoscopic guidance was successful in the treatment of an advanced cesarean scar ectopic pregnancy. This case presents images of ultrasound, magnetic resonance imaging, and gross anatomy unique to cesarean scar pregnancy. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.12.016
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:To assess the association between recent cigarette smoking (CS) in female and male partners and assisted reproduction technology (ART) outcomes. DESIGN:Cohort prospective study. SETTING:University ART program in Chile. PATIENT(S):One hundred sixty-six couples seeking pregnancy through ART. INTERVENTION(S)...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.09.073
更新日期：2010-01-01 00:00:00
abstract：:To investigate the mechanism of the antifertility action of sulfasalazine, we prospectively measured sperm density, motility, hamster oocyte penetration capacity, and reactive oxygen species production in six men with inflammatory bowel disease being treated with sulfasalazine and 8 and 16 weeks after changing to 5-am...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53050-7
更新日期：1989-11-01 00:00:00
abstract：OBJECTIVE:To introduce a combined laparovaginal metroplasty approach to the treatment of bicornuate uterus. DESIGN:Case report. SETTING:Private community hospital. PATIENT:A nulliparous patient with three recurrent spontaneous midtrimester abortions and a double uterus on hysterosalpingogram was evaluated laparoscop...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)58235-1
更新日期：1996-04-01 00:00:00
abstract：:Suppressor activity in in vitro fertilization (IVF) culture medium correlates with successful implantation. High performance liquid chromatography fractionation revealed peak(s) of inhibitory activity in the 1,000- to 5,000-Da molecular weight range. Inhibitory activity was dependent on the presence of fetal bovine se...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：OBJECTIVE:To describe a woman with a nonmosaic (45,X) form of Turner's syndrome who gave birth to a girl with 45,X Turner syndrome. DESIGN:Patient report. SETTING:Outpatient clinic of a university hospital. PATIENT(S):A woman with typical phenotypic features of Turner syndrome and a 45,X karyotype and her daughter w...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.02.129
更新日期：2004-10-01 00:00:00
abstract：:We found the prevalence of ovarian cancer in infertile women less than 40 years at the time of planned microsurgery for infertility to be 1 in 95. This may represent a greater prevalence of ovarian cancer than that of all women less than 40 years. Importantly, laparoscopy did not find the ovarian cancer in these women...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
