[Organizing pneumonia associated with the use of pegylated interferon alfa].

Abstract:

:Organizing pneumonia is a well-differentiated clinical and histologic entity whose onset is usually subacute with respiratory symptoms and pulmonary infiltrates. Its origin may be unknown (cryptogenic) or it may be associated with various medical conditions, infectious diseases, or drugs. Diagnosis is confirmed by the presence of foci of organizing pneumonia in lung biopsy specimens. Our patient was a 49-year-old man infected with the hepatitis C virus who was receiving pegylated interferon alfa-2b. He presented with dry cough, fever, dyspnea, and ground glass pulmonary infiltrates. After an open lung biopsy, he was diagnosed with organizing pneumonia. When pegylated interferon was discontinued and corticosteroids started, the symptoms and pulmonary infiltrates disappeared. To our knowledge, this is the second report of organizing pneumonia related to pegylated interferon alfa-2b.

journal_name

Arch Bronconeumol

authors

Trullas Vila JC,Padilla López DR,Bisbe Company V,Soler Simón S,Cortés Hausmann P,Bisbe Company J

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

173-4

issue

3

eissn

0300-2896

issn

1579-2129

pii

S0300-2896(08)70409-5

journal_volume

44

pub_type

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