Early symptoms and signs of cognitive deficits might not always be detectable in persons who develop Alzheimer's disease.

abstract：BACKGROUND:One in three adults, most of whom are living in a care home at the time, dies with dementia. Their end-of-life is often in hospital, where they may experience uncomfortable interventions without known benefit and die rapidly with uncontrolled pain and comfort needs. This study aimed to improve end-of-life ca...

journal_title：International psychogeriatrics

authors： Livingston G,Lewis-Holmes E,Pitfield C,Manela M,Chan D,Constant E,Jacobs H,Wills G,Carson N,Morris J

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:There is increasing interest in identifying novel cognitive paradigms to help detect preclinical dementia. Promising results have been found in clinical settings using the Semantic Interference Test (SIT), a modification of an existing episodic memory test (Fuld Object Memory Evaluation) that exploits vulner...

journal_title：International psychogeriatrics

authors： Snitz BE,Loewenstein DA,Chang CC,Lee CW,Vander Bilt J,Saxton J,Ganguli M

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:A careful characterization of behavioral abnormalities in corticobasal degeneration syndrome (CBDS) and progressive supranuclear palsy (PSP) by reliable tools is still lacking. Literature data provided evidence of the usefulness of the Frontal Behavioral Inventory (FBI) to operationalize such disturbances, p...

journal_title：International psychogeriatrics

authors： Borroni B,Alberici A,Agosti C,Cosseddu M,Padovani A

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:This article analyzes the natural history of wandering behavior throughout the course of dementia. DESIGN:Prospective, 10-year, longitudinal study of wandering behavior in dementia, with autopsy follow-up. SETTING:Participants with dementia, living at home with a carer. All lived in Oxfordshire, UK. PARTIC...

journal_title：International psychogeriatrics

authors： Hope T,Keene J,McShane RH,Fairburn CG,Gedling K,Jacoby R

更新日期：2001-06-01 00:00:00

abstract：:The authors reanalyzed previously published data from a prospectively randomized, placebo-controlled, double-blind phase-III study of 130 inpatients with dementia syndrome. The patients in the study had been diagnosed as having suffered from organic brain syndrome (ICD 290), which is the core syndrome of dementia (so-...

journal_title：International psychogeriatrics

authors： Herrmann WM,Stephan K

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The Charles Bonnet syndrome (CBS) is characterized by distinct visual hallucinations and ocularpathology causing visual impairment in patients with insight and the absence of psychiatric comorbidity. The number of reported cases of CBS is expanding as the population ages and the prevalence of vision disorder...

journal_title：International psychogeriatrics

authors： Bergman Y,Barak Y

更新日期：2013-09-01 00:00:00

abstract：:There is no doubt that family carers who look after a family member with dementia or with a functional mental illness fulfill an important role, not only for their loved one, but also for the health and aged care systems of the countries they live in. Due to increasing life expectancy, but also improved healthcare the...

journal_title：International psychogeriatrics

authors： Lautenschlager NT,Diehl-Schmid J,Loi SM,Mayer J,Tensil M,Kurz AF

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To identify, in caregivers of patients with Alzheimer's disease (AD) dementia, factors associated with subjective (personal, physical, emotional, and social) and objective (informal caregiver time and costs) caregiver burden. DESIGN:Prospective longitudinal European observational study: post-hoc analysis. S...

journal_title：International psychogeriatrics

authors： Reed C,Belger M,Scott Andrews J,Tockhorn-Heidenreich A,Jones RW,Wimo A,Dodel R,Haro JM

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Subjective memory complaints (SMC) have been suggested as an early marker of mild cognitive impairment and dementia. However, there is a paucity of evidence on the effects of early life conditions on the development of SMC in old age. This study is aimed at investigating the association between childhood soc...

journal_title：International psychogeriatrics

authors： Nishizawa T,Morita A,Fujiwara T,Kondo K

更新日期：2019-12-01 00:00:00

abstract：:Dementia is defined as global cognitive impairment that interferes with function; however, function has been less well measured than cognition in anti-dementia drug trials. In the modern era of anti-dementia clinical trials, measurement of function has improved by differentiating between the aspects of function that h...

journal_title：International psychogeriatrics

authors： Rockwood K

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Emotional distress associated with Parkinson's disease (PD) increases disease burden and decreases functioning. The literature supports the benefits of psychological interventions for amelioration of emotional distress in persons with PD. The objective of this study is to apply the Contextual Adult Lifespan ...

journal_title：International psychogeriatrics

authors： Knight B,Dissanayaka NN,Pachana NA

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:We examine the association between leisure-time activities and the risk of developing cognitive impairment among Chinese older people, and further investigate whether the association varies by educational level. METHODS:This follow-up study included 6,586 participants (aged 79.5 ± 9.8 years, range 65-105 ye...

journal_title：International psychogeriatrics

authors： Zhu X,Qiu C,Zeng Y,Li J

更新日期：2017-05-01 00:00:00

abstract：:ABSTRACTBackground:The aim of this study is to identify the prevalence and risk factors of documented delirium in general practices in Germany. METHODS:The present study includes 2,194 patients over the age of 65 years with delirium and 2,194 controls without delirium from a sample of 6,180,042 patients from 1,262 ge...

journal_title：International psychogeriatrics

authors： Bohlken J,Kostev K

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Several studies have suggested that post-traumatic stress disorder (PTSD) is related to adverse health outcomes. There are limited data on PTSD and cancer, which has a long latency period. We investigated the association between World War II (WWII)-related PTSD and subsequent breast cancer (BC) risk among Je...

journal_title：International psychogeriatrics

authors： Vin-Raviv N,Dekel R,Barchana M,Linn S,Keinan-Boker L

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Studies indicate that diet may be related to the occurrence of brain lesions. The cross-sectional association between food intake and brain lesion volumes in late-life depression was examined in a cohort of elderly individuals with current or prior depression. METHODS:Food intake was assessed in 54 elderly ...

journal_title：International psychogeriatrics

authors： Payne ME,Haines PS,Chambless LE,Anderson JJ,Steffens DC

更新日期：2007-04-01 00:00:00

abstract：:The purpose of this study was to examine the relationship between age-associated changes in central serotonergic function and abnormalities associated with major depression. Under randomized double-blind conditions, prolactin and cortisol responses to the serotonin-releasing agent d,l-fenfluramine hydrochloride (60 mg...

journal_title：International psychogeriatrics

authors： Lerer B,Gillon D,Lichtenberg P,Gorfine M,Gelfin Y,Shapira B

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Few studies have specifically examined purpose in life among very old people, and we know of none that has used a prospective approach. The aim of this study was to examine changes in purpose in life over five years in very old men and women and to investigate whether depressed mood, malnutrition, inactivity...

journal_title：International psychogeriatrics

authors： Hedberg P,Brulin C,Aléx L,Gustafson Y

更新日期：2011-06-01 00:00:00

abstract：INTRODUCTION:A considerable number of adults with dementia live in residential aged care facilities, where loneliness and boredom are common. Computer-based and electronic technologies have advanced significantly and there is potential for such technologies to improve engagement of residents with dementia. However, the...

journal_title：International psychogeriatrics

authors： Neal I,du Toit SHJ,Lovarini M

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The study aimed to evaluate the Cognitive Assessment Battery (CAB) in a specialist clinic setting in order to find out if it if it could be a supplement to the Mini-mental State Examination (MMSE) and distinguish between normal aging, mild cognitive impairment (MCI) and dementia, as well as MCI of different ...

journal_title：International psychogeriatrics

authors： Nordlund A,Påhlsson L,Holmberg C,Lind K,Wallin A

更新日期：2011-09-01 00:00:00

abstract：:Nimodipine is a calcium antagonist which improves learning and memory in brain-lesioned or aged animals (LeVere & Sandin, 1989; Schuurman & Traber, 1989). It also accelerates the recovery of experimentally damaged sciatic nerves (van der Zee et al., 1987) and reduces age-associated gait abnormalities in aging rats (Sc...

journal_title：International psychogeriatrics

authors： Schmage N,Bergener M

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Whether perceived changes in memory parallel changes in brain pathology is uncertain. Positron emission tomography (PET) scans using 2-(1-{6-[(2-[F-18]fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malononitrile (FDDNP) can measure levels of amyloid plaques and tau neurofibrillary tangles in vivo. Here we ...

journal_title：International psychogeriatrics

authors： Merrill DA,Siddarth P,Saito NY,Ercoli LM,Burggren AC,Kepe V,Lavretsky H,Miller KJ,Kim J,Huang SC,Bookheimer SY,Barrio JR,Small GW

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Despite delirium being common in older hospitalized people, little is known about its management. The aims of this study are (1) to describe the pharmacological management of delirium in an acute care setting as a baseline measure prior to the implementation of newly developed Australian guidelines; and (2) t...

journal_title：International psychogeriatrics

authors： Tropea J,Slee J,Holmes AC,Gorelik A,Brand CA

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:The economic cost of dementia is high and can be predicted by cognitive and neuropsychiatric profiles. The differential costs of the various subtypes of dementia are unknown in Argentina, and this study therefore aimed to compare these costs. METHODS:Patients with a diagnosis of dementia of Alzheimer-type (...

journal_title：International psychogeriatrics

authors： Rojas G,Bartoloni L,Dillon C,Serrano CM,Iturry M,Allegri RF

更新日期：2011-05-01 00:00:00

abstract：:Few would argue that achieving the age of 100 years is extraordinary, but what about the quality of life at this extreme age? Is it worth it to live to 100 and beyond? The study by Araújo, Ribero, Teixeira, and Paúl (2015) in three ways provided an answer to this question substantiating and complementing recent findin...

journal_title：International psychogeriatrics

authors： Martin P,Poon LW

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to investigate the psychometric characteristics of the Perceived Stress Scale (PSS) in a sample of dementia patients and their spousal caregivers. METHODS:We investigated the reliability and validity of the 14-item PSS in a sample of 80 couples, each including one spouse who...

journal_title：International psychogeriatrics

authors： Deeken F,Häusler A,Nordheim J,Rapp M,Knoll N,Rieckmann N

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Apathy, characterized by diminished motivation, is a highly prevalent neuropsychiatric symptom in dementia. However, there is a substantial knowledge gap with regard to prevalence rates, neurobiological underpinnings, and effective treatments for apathy in pre-dementia states, including mild cognitive impair...

journal_title：International psychogeriatrics

authors： Sherman C,Liu CS,Herrmann N,Lanctôt KL

更新日期：2018-02-01 00:00:00

abstract：:Over 20 years ago, the Australian Liberal/National Party Federal Opposition had a set of policies with which it hoped to persuade the Australian people to return it to government in the election due in 1996. This particular collection of proposed initiatives was called "The things that matter". When the then leader of...

journal_title：International psychogeriatrics

authors： Ames D

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:In old age, both apathy and depression have been associated with an increased cardiovascular disease (CVD) risk. This study evaluated the mediating role of cardiovascular risk factors in the relationship of apathy and mood symptoms with incident CVD. METHODS:Prospective cohort study of 1,790 community-dwell...

journal_title：International psychogeriatrics

authors： Eurelings LS,Jaccard J,Moll van Charante EP,Eikelenboom P,Ligthart SA,van Gool WA,Richard E

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:This subanalysis of a large, double-blind, placebo-controlled trial examined the prevalence of behavioral symptoms in moderate to severe Alzheimer's disease (AD), and the effect of treatment with donepezil. METHODS:Two hundred ninety patients with moderate to severe AD (standardized Mini-Mental State Examina...

journal_title：International psychogeriatrics

authors： Gauthier S,Feldman H,Hecker J,Vellas B,Ames D,Subbiah P,Whalen E,Emir B,Donepezil MSAD Study Investigators Group.

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:We assessed the relationship between cognitive impairment (including mild cognitive impairment with no signs of dementia, and dementia) and risk for depression in old age (60 years and older). METHODS:MEDLINE, EMBASE and the Cochrane Library database were used to identify potential studies. All of the clini...

journal_title：International psychogeriatrics

authors： Huang CQ,Wang ZR,Li YH,Xie YZ,Liu QX

更新日期：2011-05-01 00:00:00