Pattern of adverse drug reactions to anti-epileptic drugs: a cross-sectional one-year survey at a tertiary care hospital.

abstract：PURPOSE:We conducted a nested case-control study to evaluate the association between risk of cancer and mirtazapine use in depression patients in Taiwan. METHODS:We obtained data from the Taiwan National Health Insurance Research Database to conduct a population-based nested case-control study. The study cohort includ...

journal_title：Pharmacoepidemiology and drug safety

authors： Sun LM,Lin MC,Liang JA,Chang YJ,Chang SN,Sung FC,Muo CH,Kao CH

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To identify and quantify risk factors associated with preterm birth, stratified by gestational age at birth. METHODS:Three case-control analyses were done. Controls were pregnancies of > or =37 weeks of gestational age at birth. Cases were defined as: <28, 28-32, 33- <37 weeks of gestational age at birth respe...

journal_title：Pharmacoepidemiology and drug safety

authors： Ofori BD,Le Tiec M,Bérard A

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Previous reports have suggested that new evidence of the comparative effectiveness of different medication classes from randomized controlled trials (RCTs) does not always alter treatment decisions for first-line anti-hypertensive therapy. OBJECTIVES:To evaluate the association of RCT evidence in December 2...

journal_title：Pharmacoepidemiology and drug safety

authors： Delaney JA,McClelland RL,Furberg CD,Cooper R,Shea S,Burke G,Psaty BM

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:Ejection fraction (EF) is crucial information when studying the use and effectiveness of therapies in patients with heart failure (HF) and myocardial infarction (MI). We aimed to assess the validity of claims data-based definitions of systolic dysfunction (SD). METHODS:We identified 1072 patients with EF recor...

journal_title：Pharmacoepidemiology and drug safety

authors： Li Q,Glynn RJ,Dreyer NA,Liu J,Mogun H,Setoguchi S

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:Direct oral anticoagulants (DOACs) have been promoted in patients with nonvalvular atrial fibrillation (nv-AF) as a more convenient alternative to vitamin K antagonists. We estimated 1-year dabigatran and rivaroxaban adherence rates in nv-AF patients and assessed associations between baseline patient characteri...

journal_title：Pharmacoepidemiology and drug safety

authors： Maura G,Pariente A,Alla F,Billionnet C

更新日期：2017-11-01 00:00:00

abstract：PURPOSE:This study aimed to assess the trends in antipsychotic prescriptions for outpatients in Japan, where a community-based approach to mental healthcare is emphasized. METHODS:This descriptive epidemiological study used claims data from 1038 community pharmacies across Japan. Outpatients who were ≥18 years old and...

journal_title：Pharmacoepidemiology and drug safety

authors： Kochi K,Sato I,Nishiyama C,Tanaka-Mizuno S,Doi Y,Arai M,Fujii Y,Matsunaga T,Ogawa Y,Furukawa TA,Kawakami K

更新日期：2017-06-01 00:00:00

abstract：:Adverse drug reaction surveillance conducted by the US Federal Food and Drug Administration (FDA) is important for detecting new safety information about pharmaceuticals. FDA has sought to stimulate reporting of reactions by practitioners and manufacturers. Over the five years from 1989 to 1993, reporting more than do...

journal_title：Pharmacoepidemiology and drug safety

authors： Faich GA

更新日期：1996-11-01 00:00:00

abstract：:Dr. Walker asserts that a hypothesis always can be tested using the same data source that generated the data if the test data are independent of the data generating the hypothesis. One way to do this is to use part of the totality of data to generate the hypothesis and the other to test the hypothesis. The validity of...

journal_title：Pharmacoepidemiology and drug safety

authors： Gould AL

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:High-grade cervical dysplasia or cervical intraepithelial neoplasia grade 2 or worse has been widely used as a surrogate endpoint in cervical cancer screening or prevention trials. METHODS:To identify high-grade cervical dysplasia and cervical cancer, we developed claims-based algorithms that incorporated a...

journal_title：Pharmacoepidemiology and drug safety

authors： Kim SC,Gillet VG,Feldman S,Lii H,Toh S,Brown JS,Katz JN,Solomon DH,Schneeweiss S

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:The Canadian Network for Observational Drug Effect Studies (CNODES), a network of pharmacoepidemiologists and other researchers from seven provincial sites, provides evidence on the benefits and risks of drugs used by Canadians. The Knowledge Translation Team, one of CNODES' four main teams, evaluates the impac...

journal_title：Pharmacoepidemiology and drug safety

authors： Sketris IS,Carter N,Traynor RL,Watts D,Kelly K,following contributing members of the CNODES Knowledge Translation Team: Pierre Ernst, JM Gamble, Brenda Hemmelgarn, Colleen Metge, Michael Paterson, Robert Platt W. and Gary Teare.

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:To evaluate the outcomes of patients participating in a program of integrated care for osteoporosis in terms of medication supply, fracture incidence and expenses. METHODS:Outcomes were assessed from secondary data provided by the AOK PLUS health insurance for 2455 participants of the program and the same numb...

journal_title：Pharmacoepidemiology and drug safety

authors： Goltz L,Degenhardt G,Maywald U,Kirch W,Schindler C

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:Use of albumin (indications and quantities involved) has not been assessed in France since major changes occurred after the publication of Cochrane group meta-analysis. The objectives of this study were to measure the repartition of albumin indications in three French university hospitals in 2004 and to assess ...

journal_title：Pharmacoepidemiology and drug safety

authors： Pradel V,Tardieu S,Micallef J,Signoret A,Villano P,Gauthier L,Vanelle P,Blin O,Albumin Study Group.

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:Bayesian hierarchical models (BHMs) have been used to identify adverse drug reactions, allowing information sharing amongst adverse reactions and drugs expected to have similar properties. This study evaluated the use of BHMs in the routine signal detection analyses of potential first-trimester teratogens, wher...

journal_title：Pharmacoepidemiology and drug safety

authors： Cavadino A,Prieto-Merino D,Morris JK

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:This study examined recent trends and correlates of prescription opioid use and long-term use in the United States. METHODS:Data were from 47 356 adult participants of National Health and Nutrition Survey from 1999-2000 to 2013-2014. Participants were asked about prescription medications used in the past 30 da...

journal_title：Pharmacoepidemiology and drug safety

authors： Mojtabai R

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:Lack of control for time-varying exposures can lead to substantial bias in estimates of treatment effects. The aim of this study is to provide an overview and guidance on some of the available methodologies used to address problems related to time-varying exposure and confounding in pharmacoepidemiology and oth...

journal_title：Pharmacoepidemiology and drug safety

authors： Pazzagli L,Linder M,Zhang M,Vago E,Stang P,Myers D,Andersen M,Bahmanyar S

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:Residual confounding is a potential limitation of pharmacoepidemiologic studies, and in particular, studies based on administrative claims data that do not capture lifestyle and clinical confounders. We describe an application of the case-cohort design to assess residual confounding by thromboembolic risk facto...

journal_title：Pharmacoepidemiology and drug safety

authors： Eng PM,Seeger JD,Loughlin J,Clifford CR,Mentor S,Walker AM

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:Evidence is growing that early use of disease-modifying anti-rheumatic drugs (DMARDs) and combinations of these drugs provide optimal care for people with rheumatoid arthirits. The aim of this study was to describe objectively the pattern of consumption of DMARDs in the Australian community (community-based pre...

journal_title：Pharmacoepidemiology and drug safety

authors： Chan V,Tett SE

更新日期：2006-07-01 00:00:00

abstract：AIM:To determine the contribution of patients' adverse drug reaction (ADR) reports to signals detection, through a study of the signals sent by Lareb to the Dutch Medicines Evaluation Board. METHODS:The percentage of patient's ADR reports contributing to generate signals of adverse drug reactions was determined. A cas...

journal_title：Pharmacoepidemiology and drug safety

authors： van Hunsel F,Talsma A,van Puijenbroek E,de Jong-van den Berg L,van Grootheest K

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:Although sales of prescribed and over-the-counter (OTC) medication are rising, little is known about individual drug intake. This study was aimed to obtain complementary information about drug intake. METHOD:Information on drug utilization was obtained in a female cohort for five different time points (TP): 36...

journal_title：Pharmacoepidemiology and drug safety

authors： Hoeke H,Roeder S,Bertsche T,Borte M,von Bergen M,Wissenbach DK

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:We aim to derive an internationally applicable data set to improve prescription safety of psychiatric drugs. METHODS:We performed an in-depth analysis of the concordance of prescribing information of 10 key psychiatric drugs across four major drug markets with regard to indications, warnings and precautions, a...

journal_title：Pharmacoepidemiology and drug safety

authors： Pfistermeister B,Schenk C,Kornhuber J,Bürkle T,Fromm MF,Maas R

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:Community Pharmacists both have an important responsibility in monitoring the ongoing safety of medicines and are widely accessible to do it. This study aims to investigate the knowledge, perceptions and practice of Pharmacovigilance amongst community pharmacists in Lagos State, South West Nigeria METHODS:A cr...

journal_title：Pharmacoepidemiology and drug safety

authors： Oreagba IA,Ogunleye OJ,Olayemi SO

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:A case-control study is the most powerful design to test the risk of specific congenital malformations associated with a specific drug. However, malformation registries often lack non-malformed controls. For the Dutch EUROCAT, we collected a non-malformed control group: the 'Healthy Pregnant'. The aim of this s...

journal_title：Pharmacoepidemiology and drug safety

authors： Jentink J,Zetstra-van der Woude AP,Bos J,de Jong-van den Berg LT

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Little is known about the effects of drug-drug interactions between valacyclovir and non-steroidal anti-inflammatory drugs (NSAIDs). In this study, we analysed the adverse event 'acute kidney injury (AKI)' resulting from a possible interaction between loxoprofen (a non-selective NSAID) and valacyclovir in repor...

journal_title：Pharmacoepidemiology and drug safety

authors： Yue Z,Shi J,Jiang P,Sun H

更新日期：2014-11-01 00:00:00

abstract：:The use of healthcare databases in research provides advantages such as increased speed, lower costs and limitation of some biases. However, database research has its own challenges as studies must be performed within the limitations of resources, which often are the product of complex healthcare systems. The primary ...

journal_title：Pharmacoepidemiology and drug safety

authors： Hall GC,Sauer B,Bourke A,Brown JS,Reynolds MW,LoCasale R

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Since the introduction of therapeutic risk management regulatory guidance, an increase in the number of risk minimization interventions (RMIs) published in the literature has been observed. Methods used to evaluate their effectiveness remain, however, poorly examined. OBJECTIVE:This paper aimed to conduct...

journal_title：Pharmacoepidemiology and drug safety

authors： Gridchyna I,Cloutier AM,Nkeng L,Craig C,Frise S,Moride Y

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:We developed an adverse events (AEs) reporting form for Korean folk medicine. METHODS:The first version of the form was developed and tested in the clinical setting for spontaneous reporting of AEs. Additional revisions to the reporting form were made based on collected data and expert input. RESULTS:We devel...

journal_title：Pharmacoepidemiology and drug safety

authors： Park JH,Choi SM,Moon S,Kim S,Kim B,Kim MK,Lee S

更新日期：2017-05-01 00:00:00

abstract：:Erythromycin is commonly used to treat simple community-acquired pneumonia. We measured the prolongation in QT(c) intervals in EKGs associated with intravenous erythromycin administration among patients hospitalized for simple pneumonia (DRGs 89 and 90). We reviewed the medical records of 50 patients who received at l...

journal_title：Pharmacoepidemiology and drug safety

authors： Freeman J,Platt R

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Despite numerous clinical guidelines on asthma management, patients often receive suboptimal drug therapy. This study identified patients who received suboptimal regimens according to the National Heart, Lung and Blood Institute (NHLBI) Guidelines for the Diagnosis and Management of Asthma in a complete popu...

journal_title：Pharmacoepidemiology and drug safety

authors： Zhang T,Smith MA,Camp PG,Carleton BC

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:Our aim was to describe and assess the medicinal products and doses used for euthanasia in a series of cases, identified within an epidemiological death certificate study in Belgium, where euthanasia was until recently legally forbidden and where guidelines for euthanasia are not available. METHODS:In a random...

journal_title：Pharmacoepidemiology and drug safety

authors： Vander Stichele RH,Bilsen JJ,Bernheim JL,Mortier F,Deliens L

更新日期：2004-02-01 00:00:00

abstract：:The current medical care environment has created expectations that exceed its capabilities, one effect of which has been an increasing awareness of lapses in the quality of healthcare, including medical errors. As more new therapies reach clinical application, the expectations on the part of the public are unlikely to...

journal_title：Pharmacoepidemiology and drug safety

authors： Califf RM

更新日期：2002-06-01 00:00:00