Time trends in the use of anti-hypertensive medications: results from the Multi-Ethnic Study of Atherosclerosis.

abstract：PURPOSE:We aimed to quantify the extent of over-the-counter (OTC) low-dose aspirin use among patients in The Health Improvement Network (THIN) in the UK. METHODS:In September 2013, a random sample of low-dose aspirin users (75 past users and 75 never users) was identified based on prescriptions recorded in THIN. Prima...

journal_title：Pharmacoepidemiology and drug safety

authors： Cea Soriano L,Soriano-Gabarró M,García Rodríguez LA

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:Little is known about opioid use after bariatric surgery among patients who did not use opioids chronically before surgery. Our purpose was to determine opioid use the year after bariatric surgery among patients who did not use opioids chronically pre-surgery and to identify pre-surgery characteristics associat...

journal_title：Pharmacoepidemiology and drug safety

authors： Raebel MA,Newcomer SR,Bayliss EA,Boudreau D,DeBar L,Elliott TE,Ahmed AT,Pawloski PA,Fisher D,Toh S,Donahoo WT

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:The purpose of this paper is to describe the infrastructure of the total joint replacement registry of a large integrated healthcare system's and emphasize challenges associated with orthopedic device classification and evaluation. METHODS:Using a large integrated healthcare system innovative infrastructure in...

journal_title：Pharmacoepidemiology and drug safety

authors： Paxton EW,Ake CF,Inacio MC,Khatod M,Marinac-Dabic D,Sedrakyan A

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To examine and compare the quality of drug prescribing for older patients in nursing homes and home nursing services. METHODS:Cross-sectional study comprising 11,254 patients aged ≥ 65 years in nursing homes (n = 2986) and home nursing services (n = 8268). Potentially inappropriate medications were identified ...

journal_title：Pharmacoepidemiology and drug safety

authors： Halvorsen KH,Granas AG,Engeland A,Ruths S

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:Some studies have reported reduced risks of advanced, but not early, prostate cancer among statin users, and one study found a reduced risk only among statin users who had also used non-steroidal anti-inflammatory drugs (NSAIDs). We have previously reported no association between statin use and prostate cancer ...

journal_title：Pharmacoepidemiology and drug safety

authors： Coogan PF,Kelly JP,Strom BL,Rosenberg L

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Poor-quality patient drug information has been identified as a major cause of preventable medication errors in the United States. The US Food and Drug Administration (FDA) has the authority to require marketing authorization holders of medicinal products to implement risk evaluation and mitigation strategies...

journal_title：Pharmacoepidemiology and drug safety

authors： Chan HW,Russell AM,Smith MY

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:Innovative methods are needed to assess risks related to treatment for common medical conditions, where therapy is usually patient-directed or over-the-counter (OTC), and where tolerability, i.e. patient experienced events, may affect patterns of use. A large-scale, blinded, randomised trial was conducted to co...

journal_title：Pharmacoepidemiology and drug safety

authors： Van Ganse E,Jones JK,Moore N,Parc JM,Wall R,Schneid H

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:An increasing consumption of opioids in the general population has been reported in several countries also among pregnant women. Limited information is available regarding the effect of prenatal exposure to analgesic opioids on long-term neurocognitive function in children. The primary aim of the study was to d...

journal_title：Pharmacoepidemiology and drug safety

authors： Skovlund E,Handal M,Selmer R,Brandlistuen RE,Skurtveit S

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:To examine the association between use of methylphenidate and the risk for valvular heart disease (VHD) in the Spanish primary care database BIFAP. METHODS:Case-control study nested in a cohort of patients aged 5 to 25 years between 2002 and 2014, based in a general practice research database. Cases were peopl...

journal_title：Pharmacoepidemiology and drug safety

authors： Saiz LC,Gil M,Alonso A,Erviti J,Garjón J,Martínez M

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:Although sales of prescribed and over-the-counter (OTC) medication are rising, little is known about individual drug intake. This study was aimed to obtain complementary information about drug intake. METHOD:Information on drug utilization was obtained in a female cohort for five different time points (TP): 36...

journal_title：Pharmacoepidemiology and drug safety

authors： Hoeke H,Roeder S,Bertsche T,Borte M,von Bergen M,Wissenbach DK

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:To identify the relevant prescribing quality domains of type 2 diabetes mellitus care as a basis for the selection of a minimal set of prescribing quality indicators from a set of previously validated indicators. METHODS:We used the principal factor analysis to identify the underlying dimensions or domains o...

journal_title：Pharmacoepidemiology and drug safety

authors： Martirosyan L,Haaijer-Ruskamp FM,Braspenning J,Denig P

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:We describe the design, implementation, and use of a large, multiorganizational distributed database developed to support the Mini-Sentinel Pilot Program of the US Food and Drug Administration (FDA). As envisioned by the US FDA, this implementation will inform and facilitate the development of an active surveil...

journal_title：Pharmacoepidemiology and drug safety

authors： Curtis LH,Weiner MG,Boudreau DM,Cooper WO,Daniel GW,Nair VP,Raebel MA,Beaulieu NU,Rosofsky R,Woodworth TS,Brown JS

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:This study compared the effectiveness of rosuvastatin (RSV) to other statins prescribed in clinical practice in prevention of cardiovascular (CV) events. METHODS:This longitudinal inception cohort study, using Thomson Healthcare's MarketScan databases, included patients aged > or = 18 starting statin therapy d...

journal_title：Pharmacoepidemiology and drug safety

authors： Motsko SP,Russmann S,Ming EE,Singh VP,Vendiola RM,Jones JK

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:This study aimed to describe incidence, risk factors, and outcomes of warfarin-associated major bleeding (WAMB) in Thai patients. METHOD:A nested case-control study was conducted in a cohort of adult patients receiving ≥6 months of warfarin therapy who were prospectively followed up at a tertiary care hospital...

journal_title：Pharmacoepidemiology and drug safety

authors： Priksri W,Rattanavipanon W,Saejear W,Tanyasaensook K,Phrommintikul A,Chulavatnatol S,Nathisuwan S

更新日期：2019-07-01 00:00:00

abstract：:The UK Drug Utilization Research Group's (DURG) Regional Meeting 'New Horizons: Pharmacovigilance' was hosted by the Drug Safety Research Unit (DSRU) at Southampton on 19 May 2000. Opening the meeting, Dr Keith Beard, UK DURG chairman, welcomed delegates and speakers and thanked the DSRU team for hosting the meeting. ...

journal_title：Pharmacoepidemiology and drug safety

authors： Barnes J

更新日期：2000-09-01 00:00:00

abstract：PURPOSE:To define periods of acceptable mortality reporting in primary care and to demonstrate through examples the implication for research using automated medical data. METHODS:Annual death counts were obtained for each primary care practice participating in The Health Improvement Network "THIN" (UK). Expected count...

journal_title：Pharmacoepidemiology and drug safety

authors： Maguire A,Blak BT,Thompson M

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Type 2 diabetes is associated with increased cardiovascular risk. The comparative effectiveness of statin plus fibrate combination therapy and statin monotherapy in reducing risk of cardiovascular disease in real-world settings is unknown. METHODS:A retrospective database analysis was performed using a large m...

journal_title：Pharmacoepidemiology and drug safety

authors： Suh HS,Hay JW,Johnson KA,Doctor JN

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:Lack of control for time-varying exposures can lead to substantial bias in estimates of treatment effects. The aim of this study is to provide an overview and guidance on some of the available methodologies used to address problems related to time-varying exposure and confounding in pharmacoepidemiology and oth...

journal_title：Pharmacoepidemiology and drug safety

authors： Pazzagli L,Linder M,Zhang M,Vago E,Stang P,Myers D,Andersen M,Bahmanyar S

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To examine the effects of analgesics on bone mineral density (BMD), which have not been examined in a longitudinal study with multiple measurements. METHODS:We investigated changes in BMD associated with new use of analgesics in a prospective longitudinal cohort of mid-life women. BMD and medication use were m...

journal_title：Pharmacoepidemiology and drug safety

authors： Yoshida K,Yu Z,Greendale GA,Ruppert K,Lian Y,Tedeschi SK,Lin TC,Haneuse S,Glynn RJ,Hernández-Díaz S,Solomon DH

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:Many patients use complementary/alternative medicine (CAM) for their health problems especially where long-term treatment is required. Epilepsy is the most prevalent neurological disorder requiring long-term treatment and compliance. The purpose of the study was to establish the pattern of use of CAM in epilept...

journal_title：Pharmacoepidemiology and drug safety

authors： Tandon M,Prabhakar S,Pandhi P

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:Risk assessment for natural health products (NHPs) may not be evaluated similarly to therapeutic products by Health Canada in terms of notification of harms to consumers and health professionals. In this descriptive study, we evaluated risk communications (RCs) issued by Health Canada for NHPs and for therapeut...

journal_title：Pharmacoepidemiology and drug safety

authors： Bateman J,Charrois TL,Gardiner P,Vohra S

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to generate data regarding the drug utilization pattern in pediatric population of our tertiary care hospital so that we could generate an essential medicine list (EML). BACKGROUND:Drug therapy accounts for a major portion of expenditure toward health care. Reduction in health ...

journal_title：Pharmacoepidemiology and drug safety

authors： Singh I,Mittal R,Shafiq N,Bharati B,Nigah RK,Pandhi P,Chaudhary RR,Malhotra S

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:The Dietary Supplements Information Expert Committee (DSI-EC; the Committee) of the United States Pharmacopeial Convention (USP) reviews safety profiles of dietary supplements before development of USP-National Formulary (USP-NF) quality monographs. Because the veracity of dietary supplement adverse event repor...

journal_title：Pharmacoepidemiology and drug safety

authors： Gardiner P,Sarma DN,Low Dog T,Barrett ML,Chavez ML,Ko R,Mahady GB,Marles RJ,Pellicore LS,Giancaspro GI

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Antiepileptic drugs (AEDs) are also prescribed for therapeutic indications other than epilepsy (EPI), namely, psychiatric disorders (PSY). Our aim was to develop an algorithm able to distinguish between EPI and PSY among childbearing age women based on differences in AED exposure in these patient groups. ME...

journal_title：Pharmacoepidemiology and drug safety

authors： Naldi I,Piccinni C,Mostacci B,Renzini J,Accetta G,Bisulli F,Tappatà M,Piazza A,Pagano P,Bianchi S,D'Alessandro R,Tinuper P,Poluzzi E,ESPEA (Emilia-Romagna Study on Pregnancy and Exposure to Antiepileptic drugs) Group.

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:We examined the length and continuity of antidepressant treatment and factors associated with long-term of treatment among adults. METHODS:Nationwide data from all reimbursed antidepressant prescriptions in 1994-2003 were linked with patients' data retrieved from Statistics Finland and the Finnish Hospital D...

journal_title：Pharmacoepidemiology and drug safety

authors： Sihvo S,Wahlbeck K,McCallum A,Sevon T,Arffman M,Haukka J,Keskimäki I,Hemminki E

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:To determine healthcare claim patterns associated using nonsteroidal anti-inflammatory drugs (NSAIDs) for rheumatoid arthritis (RA). METHODS:The CADEUS study randomly identified NSAID users within the French health insurance database. One-year claims data were extracted, and NSAID indication was obtained from ...

journal_title：Pharmacoepidemiology and drug safety

authors： Bernard MA,Bénichou J,Blin P,Weill A,Bégaud B,Abouelfath A,Moore N,Fourrier-Réglat A,CADEUS Team.

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Increased post-marketing reports of 'interstitial pneumonia' as an adverse drug reaction (ADR) from the use of gefitinib, irinotecan, or leflunomide among patients in Japan have not been noted in other countries. The WHO International Drug Monitoring Database was analyzed to examine Japan's pattern of reporting...

journal_title：Pharmacoepidemiology and drug safety

authors： Koo LC,Clark JA,Quesenberry CP,Higenbottam T,Nyberg F,Wolf MK,Steinberg MH,Forsythe BH

更新日期：2005-11-01 00:00:00

abstract：PURPOSE:To examine and compare risks of serious hypoglycemia among antidiabetic monotherapy-treated adults receiving metformin, a sulfonylurea, a meglitinide, or a thiazolidinedione. METHODS:We performed a retrospective cohort study of apparently new users of monotherapy with metformin, glimepiride, glipizide, glyburi...

journal_title：Pharmacoepidemiology and drug safety

authors： Leonard CE,Han X,Brensinger CM,Bilker WB,Cardillo S,Flory JH,Hennessy S

更新日期：2018-01-01 00:00:00

abstract：:Erythromycin is commonly used to treat simple community-acquired pneumonia. We measured the prolongation in QT(c) intervals in EKGs associated with intravenous erythromycin administration among patients hospitalized for simple pneumonia (DRGs 89 and 90). We reviewed the medical records of 50 patients who received at l...

journal_title：Pharmacoepidemiology and drug safety

authors： Freeman J,Platt R

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:To evaluate the effect of the consumption of benzodiazepines at age 40-42 years on prescription of opioids later in life. METHODS:A cohort of 6707 men and 6683 women aged 40-42 years reported no use of analgesics in health surveys in 1985-1989. This cohort was linked to the Norwegian prescription database (Nor...

journal_title：Pharmacoepidemiology and drug safety

authors： Skurtveit S,Furu K,Bramness JG,Tverdal A

更新日期：2008-09-01 00:00:00