Acute kidney injury during concomitant use of valacyclovir and loxoprofen: detecting drug-drug interactions in a spontaneous reporting system.

abstract：PURPOSE:De-implementation of low-value services among patients with limited life expectancy is challenging. Robust mortality prediction models using routinely collected health care data can enhance health care stakeholders' ability to identify populations with limited life expectancy. We developed and validated a claim...

journal_title：Pharmacoepidemiology and drug safety

authors： Lund JL,Kuo TM,Brookhart MA,Meyer AM,Dalton AF,Kistler CE,Wheeler SB,Lewis CL

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To evaluate the outcomes of patients participating in a program of integrated care for osteoporosis in terms of medication supply, fracture incidence and expenses. METHODS:Outcomes were assessed from secondary data provided by the AOK PLUS health insurance for 2455 participants of the program and the same numb...

journal_title：Pharmacoepidemiology and drug safety

authors： Goltz L,Degenhardt G,Maywald U,Kirch W,Schindler C

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:To evaluate the effect of the consumption of benzodiazepines at age 40-42 years on prescription of opioids later in life. METHODS:A cohort of 6707 men and 6683 women aged 40-42 years reported no use of analgesics in health surveys in 1985-1989. This cohort was linked to the Norwegian prescription database (Nor...

journal_title：Pharmacoepidemiology and drug safety

authors： Skurtveit S,Furu K,Bramness JG,Tverdal A

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:We aimed to investigate the association between psychotropic treatment and risk of burn injury in individuals with mental illness. METHODS:A nested case-control study was conducted by using the National Health Insurance Research Database in Taiwan. A total of 3187 cases with burn injury under International Cla...

journal_title：Pharmacoepidemiology and drug safety

authors： Chang CM,Wu KY,Chiu YW,Wu HT,Tsai YT,Chau YL,Tsai HJ

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:The purposes of the study are to compare safety specifications between Japan and the European Union (EU) and to identify the factors affecting categorization of important identified or potential risks. METHODS:Safety specifications were collected from orphan and nonorphan drugs approved in Japan between 2014 a...

journal_title：Pharmacoepidemiology and drug safety

authors： Hirota S,Yamaguchi T

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:The aims of this study are to examine the validity of diagnostic codes for psoriatic arthritis in The Health Improvement Network (THIN) and to examine the agreement between General Practitioner (GP) report and prescription records for disease modifying antirheumatic drugs (DMARDs). METHODS:Questionnaires were ...

journal_title：Pharmacoepidemiology and drug safety

authors： Ogdie A,Alehashemi S,Love TJ,Jiang Y,Haynes K,Hennessy S,Choi H,Gelfand JM

更新日期：2014-09-01 00:00:00

abstract：PURPOSES:To describe the kind of the difficulties encountered when seeking research governance approval for a nationwide public health and genetic study-the Drug-Induced Arrhythmia Risk Evaluation study-in England. METHODS:Description of the processes followed when seeking research governance approval for the Drug-Ind...

journal_title：Pharmacoepidemiology and drug safety

authors： Boshier A,Shakir SA,Telfer P,Behr E,Pakrashi T,Camm AJ

更新日期：2005-06-01 00:00:00

abstract：PURPOSE:To determine healthcare claim patterns associated using nonsteroidal anti-inflammatory drugs (NSAIDs) for rheumatoid arthritis (RA). METHODS:The CADEUS study randomly identified NSAID users within the French health insurance database. One-year claims data were extracted, and NSAID indication was obtained from ...

journal_title：Pharmacoepidemiology and drug safety

authors： Bernard MA,Bénichou J,Blin P,Weill A,Bégaud B,Abouelfath A,Moore N,Fourrier-Réglat A,CADEUS Team.

更新日期：2012-06-01 00:00:00

abstract：:When a biological hypothesis of causal effect can be inferred, the hypothesis can sometimes be tested in the selfsame database that gave rise to the study data from which the hypothesis grew. Valid testing happens when the inferred biological hypothesis has scientific implications that predict new relations between ob...

journal_title：Pharmacoepidemiology and drug safety

authors： Walker AM

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:To examine the utility of electronic health records from a routine care setting in assessing comparative effectiveness of fourth-line anti-hypertensive drugs to treat resistant hypertension. METHODS:We conducted a cohort study using the Clinical Practice Research Datalink: a repository of electronic health rec...

journal_title：Pharmacoepidemiology and drug safety

authors： Sinnott SJ,Smeeth L,Williamson E,Perel P,Nitsch D,Tomlinson LA,Douglas IJ

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:PCORnet, the National Patient-Centered Clinical Research Network, represents an innovative system for the conduct of observational and pragmatic studies. We describe the identification and validation of a retrospective cohort of patients with type 2 diabetes (T2DM) from four PCORnet sites. METHODS:We adapted e...

journal_title：Pharmacoepidemiology and drug safety

authors： Wiese AD,Roumie CL,Buse JB,Guzman H,Bradford R,Zalimeni E,Knoepp P,Morris HL,Donahoo WT,Fanous N,Epstein BF,Katalenich BL,Ayala SG,Cook MM,Worley KJ,Bachmann KN,Grijalva CG,Rothman RL,Chakkalakal RJ

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:European Surveillance of Congenital Anomalies (EUROCAT) is a network of population-based congenital anomaly registries in Europe surveying more than 1 million births per year, or 25% of the births in the European Union. This paper describes the potential of the EUROCAT collaboration for pharmacoepidemiology ...

journal_title：Pharmacoepidemiology and drug safety

authors： Meijer WM,Cornel MC,Dolk H,de Walle HE,Armstrong NC,de Jong-van den Berg LT,EUROCAT Working Group.

更新日期：2006-09-01 00:00:00

abstract：:It is surprising to see how consumer Adverse Drug Reaction (ADR) reports have been continuously increasing for the last few years in Europe. This probably results from the influence of United States (US) market where the patients feels justified in telephoning the pharmaceutical companies directly with queries regardi...

journal_title：Pharmacoepidemiology and drug safety

authors： Fleuranceau-Morel P

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the effect of the length of the drug free period on incidence measurements as well as on cohort characteristics in users of antidepressants. METHODS:The study population consisted of patients aged 18 years or older who filled a prescription for an antidepressant drug in th...

journal_title：Pharmacoepidemiology and drug safety

authors： Gardarsdottir H,Heerdink ER,Egberts AC

更新日期：2006-05-01 00:00:00

abstract：PURPOSE:The objective of this study was to quantify rates of adverse events in a high-risk multi-morbid population of institutionalized patients with Alzheimer's disease (AD). METHODS:We conducted a retrospective cohort study among nursing home residents diagnosed with AD and psychosis during January 1998 to October 1...

journal_title：Pharmacoepidemiology and drug safety

authors： Oliveria SA,Liperoti R,L'italien G,Pugner K,Safferman A,Carson W,Lapane K

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:Determination of the incidence rate of diabetic ketoacidosis (DKA) in type 2 diabetes mellitus (T2DM) is urgent, in response to the safety issue with use of the glucose lowering drugs, sodium-glucose cotransporter-2 inhibitors, and DKA. METHODS:We extracted data of adult patients with T2DM from a medical claim...

journal_title：Pharmacoepidemiology and drug safety

authors： Takeuchi M,Kawamura T,Sato I,Kawakami K

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine epidemiologic characteristics of Adverse Drug Events (ADEs) among children and adolescents presenting to an Emergency Department (ED) in Newfoundland and Labrador (NL), Canada. MATERIALS AND METHODS:This study was conducted in three phases and included an ED chart review...

journal_title：Pharmacoepidemiology and drug safety

authors： Sikdar KC,Alaghehbandan R,Macdonald D,Barrett B,Collins KD,Gadag V

更新日期：2010-02-01 00:00:00

abstract：PURPOSE:Research using healthcare databases often includes patients frequently excluded from clinical trials; yet it is not known whether commonly used data represents the overall population or specific sub-populations of interest. We aimed to examine population representativeness from data sources in recent research s...

journal_title：Pharmacoepidemiology and drug safety

authors： Kaviani P,Landi SN,McKethan A,Brookhart MA,McGrath LJ

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:Medicaid programs are concerned about inappropriate, potentially hazardous, and costly off-label use of second-generation antipsychotics (SGAs). Several states are exploring policies aimed at managing low-dose quetiapine, commonly prescribed for off-label conditions. This study aimed to characterize longitudina...

journal_title：Pharmacoepidemiology and drug safety

authors： Hartung DM,Zerzan J,Yamashita T,Tong S,Morden NE,Libby AM

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:The aim of this work was to study the use of systemic antibacterials and its possible determinants in Hungarian intensive care units (ICUs). METHODS:Hospital pharmacy. departments provided package level dispensing data for their corresponding ICU (2006). Data were converted into defined daily doses (DDDs) and ...

journal_title：Pharmacoepidemiology and drug safety

authors： Benko R,Matuz M,Peto Z,Bogár L,Viola R,Doró P,Soós G,Hajdú E

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To conduct a synthesis of the literature on methods to evaluate the impacts of FDA regulatory actions and identify best practices for future evaluations. METHODS:We searched MEDLINE for manuscripts published between January 1948 and August 2011 that included terms related to FDA, regulatory actions, and empiri...

journal_title：Pharmacoepidemiology and drug safety

authors： Briesacher BA,Soumerai SB,Zhang F,Toh S,Andrade SE,Wagner JL,Shoaibi A,Gurwitz JH

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To examine the effects of analgesics on bone mineral density (BMD), which have not been examined in a longitudinal study with multiple measurements. METHODS:We investigated changes in BMD associated with new use of analgesics in a prospective longitudinal cohort of mid-life women. BMD and medication use were m...

journal_title：Pharmacoepidemiology and drug safety

authors： Yoshida K,Yu Z,Greendale GA,Ruppert K,Lian Y,Tedeschi SK,Lin TC,Haneuse S,Glynn RJ,Hernández-Díaz S,Solomon DH

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To assess the feasibility of using Clinical Practice Research Datalink (CPRD) data for identifying populations of patients with chronic obstructive pulmonary disease (COPD) eligible for a hypothetical pragmatic trial. METHODS:A retrospective multidatabase cohort study using CPRD primary care and linked seconda...

journal_title：Pharmacoepidemiology and drug safety

authors： Requena G,Wolf A,Williams R,Dedman D,Quint JK,Murray-Thomas T,Pimenta JM

更新日期：2020-12-27 00:00:00

abstract：PURPOSE:To explore associations between preterm birth and use of medications in young adulthood as a proxy for different diseases. METHODS:We linked data on birth characteristics from the Medical Birth Registry of Norway (1967-1999) and the Norwegian Prescription Database (2004-2015). Individuals born as singletons du...

journal_title：Pharmacoepidemiology and drug safety

authors： Engeland A,Bjørge T,Klungsøyr K,Skurtveit S,Furu K

更新日期：2017-07-01 00:00:00

abstract：PURPOSE:To identify and quantify risk factors associated with preterm birth, stratified by gestational age at birth. METHODS:Three case-control analyses were done. Controls were pregnancies of > or =37 weeks of gestational age at birth. Cases were defined as: <28, 28-32, 33- <37 weeks of gestational age at birth respe...

journal_title：Pharmacoepidemiology and drug safety

authors： Ofori BD,Le Tiec M,Bérard A

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:The thorough analysis of special drug characteristics requires information on the specific brand of a drug. This information is often not sought in pharmacoepidemiologic surveys although in many countries packages are labelled with an unequivocal code (in Germany called Pharmazentralnummer (PZN)). We aimed to a...

journal_title：Pharmacoepidemiology and drug safety

authors： Quinzler R,Schmitt SP,Szecsenyi J,Haefeli WE

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:Proton pump inhibitor (PPI) may suppress adrenal cortical steroid synthesis and release, thereby leading to electrolyte disturbances. Both hyponatremia and hyperkalemia in the setting of PPI therapy have been documented in case reports. The objective of this study was to examine the association between serum po...

journal_title：Pharmacoepidemiology and drug safety

authors： Gau JT,Heh V,Acharya U,Yang YX,Kao TC

更新日期：2009-09-01 00:00:00

abstract：PURPOSE:To characterize the nature of a heparin contaminant's clinical effects in cases reported to the Adverse Event Reporting System (AERS). The FDA received reports of heparin-associated adverse events (AEs) starting in late 2007-early 2008 during a national investigation of allergic-type events. The investigation i...

journal_title：Pharmacoepidemiology and drug safety

authors： McMahon AW,Pratt RG,Hammad TA,Kozlowski S,Zhou E,Lu S,Kulick CG,Mallick T,Dal Pan G

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:Propensity scores are used in observational studies to adjust for confounding, although they do not provide control for confounders omitted from the propensity score model. We sought to determine if tests used to evaluate logistic model fit and discrimination would be helpful in detecting the omission of an imp...

journal_title：Pharmacoepidemiology and drug safety

authors： Weitzen S,Lapane KL,Toledano AY,Hume AL,Mor V

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:Three recent observational studies reported that the risk of fatal overdose is greater with venlafaxine than SSRI use. It is not clear whether patient factors could account for this finding. We evaluated whether risk factors for suicide are more prevalent among patients prescribed venlafaxine than patients pres...

journal_title：Pharmacoepidemiology and drug safety

authors： Mines D,Hill D,Yu H,Novelli L

更新日期：2005-06-01 00:00:00