Antimicrobial potential of Glycyrrhiza glabra roots.

Abstract:

:The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 microg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H(37)Ra and H(37)Rv strains at 29.16 microg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.

journal_name

J Ethnopharmacol

authors

Gupta VK,Fatima A,Faridi U,Negi AS,Shanker K,Kumar JK,Rahuja N,Luqman S,Sisodia BS,Saikia D,Darokar MP,Khanuja SP

doi

10.1016/j.jep.2007.11.037

subject

Has Abstract

pub_date

2008-03-05 00:00:00

pages

377-80

issue

2

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(07)00640-X

journal_volume

116

pub_type

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