Abstract：
OBJECTIVE:We present a case of triplet pregnancy with a complete hydatidiform mole, a condition carrying a significant risk to both mother and fetuses and, therefore, raising an important issue on prenatal care. CASE REPORT:A 36-year-old patient with gonadal dysgenesis and a 46,XY karyotype successfully conceived a triplet pregnancy after oocyte donation and in vitro fertilization. At mid-trimester, the pregnancy was seen harboring a hydatidiform mole along with two other fetuses by ultrasound. Fetal karyotyping of both fetuses revealed normal results. Serum human chorionic gonadotropin levels were followed up throughout the remainder of pregnancy. At 33 weeks of gestation, preeclampsia ensued with worsening of maternal renal function and high blood pressure, so cesarean section was arranged to deliver a set of two surviving twins. Prophylactic bilateral gonadectomy was done at the same time to curtail the possibility of future malignancy development. Upon pathologic examination of the placentae, hydropic chorionic villi with central cistern formation and nonpolar trophoblastic hyperplasia with atypia and necrosis were found, compatible with complete hydatidiform mole. The gonads showed streaks of fibrous tissue, which resembled ovarian stroma and hilus cells, and an unremarkable tube. Maternal serum human chorionic gonadotropin levels declined gradually to normal level at two months after delivery. CONCLUSION:This is the first report of triplet pregnancy complicated with one complete hydatidiform mole and preeclampsia in a 46,XY female with gonadal dysgenesis. Our case demonstrated that prolonged gestation with both surviving fetuses was possible by applying intensive monitoring of the whole pregnancy.
journal_name
Taiwan J Obstet Gynecoljournal_title
Taiwanese journal of obstetrics & gynecologyauthors
Ko PC,Peng HH,Soong YK,Chang SDdoi
10.1016/S1028-4559(08)60034-0subject
Has Abstractpub_date
2007-09-01 00:00:00pages
276-80issue
3eissn
1028-4559issn
1875-6263pii
S1028-4559(08)60034-0journal_volume
46pub_type
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journal_title：Taiwanese journal of obstetrics & gynecology
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journal_title：Taiwanese journal of obstetrics & gynecology
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journal_title：Taiwanese journal of obstetrics & gynecology
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journal_title：Taiwanese journal of obstetrics & gynecology
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更新日期：2010-12-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,多中心研究
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journal_title：Taiwanese journal of obstetrics & gynecology
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journal_title：Taiwanese journal of obstetrics & gynecology
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更新日期：2016-12-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2015.08.028
更新日期：2016-12-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/S1028-4559(08)60024-8
更新日期：2007-09-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2013.12.010
更新日期：2015-06-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/S1028-4559(10)60090-3
更新日期：2010-12-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/S1028-4559(08)60125-4
更新日期：2008-09-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2013.04.017
更新日期：2013-06-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.tjog.2020.07.002
更新日期：2020-09-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
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更新日期：2018-02-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
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journal_title：Taiwanese journal of obstetrics & gynecology
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pub_type： 杂志文章
doi：10.1016/S1028-4559(10)60070-8
更新日期：2010-09-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2020.07.012
更新日期：2020-09-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
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更新日期：2020-03-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2017.04.018
更新日期：2017-06-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2020.01.008
更新日期：2020-03-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 临床试验,杂志文章
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更新日期：2006-12-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2018.06.017
更新日期：2018-08-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.tjog.2013.01.029
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:Primary adenoid cystic carcinoma (ACC) of Bartholin's gland is a rare gynecologic malignancy. We report two cases from primary treatment to recurrence and the adjuvant treatment. CASE REPORT:A woman aged 37 years presented with a mass on the right posterior labia minor and underwent right radical hemi-vulvec...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.tjog.2012.10.005
更新日期：2013-03-01 00:00:00
abstract：:To assess the roles of the low molecular weight heparin (LMWH) on recurrent pregnancy loss (RPL). The relevant studies of all randomized controlled trials (RCTs) were retrieved, and the systematic evaluation was conducted. PubMed, Embase, and Cochrane library databases were searched by using keywords, including low-mo...
journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.tjog.2020.11.001
更新日期：2021-01-01 00:00:00
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journal_title：Taiwanese journal of obstetrics & gynecology
pub_type： 杂志文章
doi：10.1016/j.tjog.2013.12.001
更新日期：2014-03-01 00:00:00
