Abstract:
OBJECTIVE:We present prenatal diagnosis of hydrancephaly and enlarged cerebellum and cisterna magna in a fetus with thanatophoric dysplasia type II (TD2) and a review of prenatal diagnosis of brain anomalies associated with TD. CASE REPORT:A 33-year-old woman was referred for genetic counseling at 25 weeks of gestation because of fetal ultrasound abnormalities. Prenatal ultrasound at 14 weeks of gestation revealed an increased nuchal translucency (NT) and hydrocephalus. Level II ultrasound examination at 25 weeks of gestation revealed hydrancephaly, macrocephaly, a cloverleaf skull, frontal bossing, enlarged cerebellum and cisterna magna, a narrow chest, small ribs, short straight limbs. Amniocentesis revealed a karyotype of 46,XX. FGFR3 mutation analysis using the DNA extracted from uncultured amniocytes revealed a genotype of WT/c.1948A>G (p.Lys650Glu). The result was consistent with a K650E mutation in FGFR3 and TD2. The pregnancy was subsequently terminated. CONCLUSION:Fetuses with TD2 may present increased NT, early onset hydrocephalus, enlarged cerebellum and cisterna magna, and hydrancephaly on prenatal ultrasound.
journal_name
Taiwan J Obstet Gynecoljournal_title
Taiwanese journal of obstetrics & gynecologyauthors
Chen CP,Chang TY,Lin TW,Chern SR,Chen SW,Lai ST,Chuang TY,Wang Wdoi
10.1016/j.tjog.2017.12.020subject
Has Abstractpub_date
2018-02-01 00:00:00pages
119-122issue
1eissn
1028-4559issn
1875-6263pii
S1028-4559(17)30314-5journal_volume
57pub_type
杂志文章,评审abstract:OBJECTIVE:To demonstrate a case with a vulvar metastasis masquerading a primary vulvar malignancy. The clinical and histological features, mechanism, and impact to the prognosis are discussed. CASE REPORT:A 58-year-old woman presented to gynecologist for abnormal vaginal discharge. A vulvar nodule was noticed during p...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2017.12.035
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVE:Cellular leiomyoma is characterized by significantly increased cellularity and may mimic malignant tumors. Our aim was to differentiate these from other malignant small round-cell tumors. CASE REPORT:We report a case of cellular leiomyoma that mimicked a malignant small round-cell tumor upon frozen section e...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(10)60043-5
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To compare the safety and effectiveness of the harmonic scalpel and conventional electrosurgery in laparoscopic myomectomy (LM). MATERIALS AND METHODS:We performed a retrospective chart review of 591 women with symptomatic uterine fibroids who underwent LM. Thirty-three cases of LMs with harmonic scalpel (LM...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.12.023
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to describe our experience with the diagnosis and management of acquired uterine vascular abnormalities associated with persistent human chorionic gonadotropin (hCG). Through this case series, we sought to establish our protocol for the treatment and follow-up of uterine vascular les...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2014.06.008
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:In nonimmune pregnant woman, the primary infection with parvovirus B19 may lead to transplacental transmission to the fetus with variable outcomes, including congenital anemia, hydrops fetalis, fetal death or spontaneous resolution. CASE REPORT:The first case was of a 28-year-old woman, gravida 2, para 1, wh...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/s1028-4559(08)60014-5
更新日期:2007-12-01 00:00:00
abstract::Abnormal umbilical artery flow with absent or reversed end-diastolic velocity (AREDV) during pregnancy is a strong indication of placental insufficiency. When AREDV occurs prenatally, a close follow-up or expeditious delivery should be contemplated. AREDV in the umbilical artery is associated with intraventricular hem...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1016/S1028-4559(09)60294-1
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:Patients with Long QT syndrome (LQTS) P may present with torsades de pointes, ventricular tachycardia (VT), or ventricular fibrillation (VF) and are at risk of sudden cardiac death. MATERIALS AND METHODS:A 38 y/o female patient with uterus myoma developed VF during laparoscopic assisted vaginal hysterectomy ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2019.05.031
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To explore the changes in placental gene expression between women with preeclampsia and those with superimposed preeclampsia on chronic hypertension. MATERIALS AND METHODS:In Taiwanese population, we compared gene expression between the placentas from preeclamptic patients and those with superimposed preecla...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2011.07.005
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVE:Endometriosis is a chronic inflammatory disease pathologically defined as the presence of endometrial-like tissue outside the uterine cavity. It is one of the most important diseases affecting women of reproductive age. The process of endometriotic implant growth is mediated by many complex interactions of im...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.07.004
更新日期:2016-04-01 00:00:00
abstract::Placenta previa poses a high risk for massive hemorrhage, from the antenatal period until after Cesarean section. This condition increases the risk of maternal and neonatal mortality and morbidity. In cases of placenta previa, the prenatal prediction of sudden bleeding during pregnancy and blood loss during Cesarean s...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.tjog.2012.01.002
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:This study was aimed to identify the physical and mental state of women after delivery, to investigate the factors that influence those, and to examine the effects of postpartum care performance, which is traditionally believed to be appropriate care in Korea, on women's physical and mental status. MATERIALS...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2014.04.030
更新日期:2015-08-01 00:00:00
abstract::Intrauterine adhesion is a severe complication after intrauterine operation, Various adjuvant therapies failed to improve clinical symptoms and pregnancy rates among patients with moderate-to-severe intrauterine adhesion. At present, hyaluronic acid gel is widely used in the primary prevention of adhesion after hyster...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.tjog.2019.09.002
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between placental transthyretin (TTR) level and preeclampsia. MATERIALS AND METHODS:Placental tissues from uncomplicated and preeclamptic pregnancies were analyzed using immunohistochemistry and image analysis. We measured the mean optical density (OD) of immunohistochemical s...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2016.04.014
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To analyze the interaction between ACP1 and PTPN22 concerning their effects on the growth of the tumor. In previous paper we have shown (i) that ACP1*B/*B genotype of ACP1 is negatively associated with the growth of leiomyomas and (ii) that there is a negative association of *C/*C genotype of PTPN22 with tumo...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.06.017
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:We present a case of type I diastematomyelia diagnosed with ultrasonography at the 14th week of gestation. CASE REPORT:A 26-year-old primigravida at 14 weeks' gestation was presented to our outpatient department with a complaint of dysuria. Routine antenatal ultrasound revealed disruption of the fetal upper ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/S1028-4559(09)60279-5
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:To study the possible non-genomic effect of selective estrogen receptor modulators on human dermal fibroblasts (HDF). MATERIALS AND METHODS:WS1 cells were used to test the effect of raloxifene. The mRNA expressions of estrogen receptor (ER) α and β and G protein-coupled ER 1(GRP30) were examined by reverse t...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2011.10.013
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:The gold standard procedure for treating patients with apical pelvic organ prolapse (POP) is sacrocolpopexy. However, no report comparing the two types of single-incision robotic sacrocolpopexy, namely, single-site robotic sacrocolpopexy (SS-RSC) and single-port robotic sacrocolpopexy (SP-RSC) exists. Therefo...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2020.10.007
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:In order to compare the trends and improvements of prenatal diagnosis of gastroschisis, we herein retrospectively reviewed our cases of fetal gastroschisis detected by three-dimensional ultrasound (3D US) between the two centuries. MATERIALS AND METHODS:We reviewed our computer database of prenatal diagnosis...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2013.04.007
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:Obstetricians have longer work hours and work hour restriction of employed physicians will be implemented thereafter. This study was to survey the impact of work hour restriction and determine the weekly work hours of obstetricians. MATERIALS AND METHODS:Since December 1, 2017, to January 31, 2018, a questio...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2018.10.005
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to define the pregnancy and oncologic outcomes after fertility-sparing treatment of atypical hyperplasia (AH)/endometrial intraepithelial neoplasia (EIN) and early-stage endometrioid endometrial cancer (EEC). MATERIALS AND METHODS:The retrospective cohort study included patients...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2020.03.014
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:To examine the alteration in the cellular dynamics of the urethral tissue after a simulated birth trauma in a mouse model. MATERIALS AND METHODS:A total of 36 B6 mice received vaginal distention treatment, and four untreated mice were used as controls. Specimens were collected every 24 hours after the injury...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2015.10.026
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:Primary adenoid cystic carcinoma (ACC) of Bartholin's gland is a rare gynecologic malignancy. We report two cases from primary treatment to recurrence and the adjuvant treatment. CASE REPORT:A woman aged 37 years presented with a mass on the right posterior labia minor and underwent right radical hemi-vulvec...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.tjog.2012.10.005
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:To assess the long-term outcomes of laparoscopic staging surgery (LSS) in treating patients with endometrial carcinoma. MATERIALS AND METHODS:Patients with endometrial cancer who underwent LSS between June 1995 and June 2014 were prospectively registered. Perioperative data, complications, disease recurrence...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2016.04.035
更新日期:2016-08-01 00:00:00
abstract::Prenatal screening with alpha-fetoprotein (AFP) and ultrasonography have allowed the prenatal diagnosis of neural tube defects (NTDs) in current obstetric care, and open spina bifida has been considered a potential candidate for in utero treatment in modern pediatric surgery. This article provides an overview of mater...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1016/S1028-4559(08)60125-4
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the percentage of pregnant women with negative Group B Streptococcus (GBS) screening results by culture at 35 weeks' gestation, who subsequently had positive GBS test results after 39 weeks' gestation. MATERIALS AND METHODS:From 2006 to 2007, we recruited 150 pregnant wo...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 临床试验,杂志文章
doi:10.1016/S1028-4559(09)60269-2
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:We describe our experience with serial uterine artery embolization (UAE) combined with standard weekly methotrexate and a eight-day methotrexate/folinic acid (MTX/FA) treatment regimen in the management of placenta accreta spectrum (PAS) disorder at 7 weeks of gestation. CASE REPORT:A 38-year-old woman, grav...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type:
doi:10.1016/j.tjog.2020.09.027
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVES:An increase in the proportion of male-to-female live births has raised concerns in Taiwan. Disclosure of fetal sex during prenatal screening is not allowed by the Taiwan government. Fetal sex annotation in clinical genetic reports is also prohibited. This study tested the hypothesis that the male-to-female s...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2012.09.012
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:To assess the effect of metalloestrogen cadmium (Cd) on the proliferation of endometrial stromal cells (ESC) isolated from the eutopic endometrium of women with endometriosis MATERIALS AND METHODS:ESC were isolated from eutopic endometrial samples from 10 women with endometriosis and 10 women without endomet...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2013.10.015
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:This prospective study presents a preliminary result to compare the clinical efficacy of patients with stress urinary incontinence and mixed urinary incontinence using minimal invasive Er:YAG vaginal laser. MATERIALS AND METHODS:A total of 20 patients were included, in which were 10 patients with SUI and 10 ...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章
doi:10.1016/j.tjog.2019.07.006
更新日期:2019-09-01 00:00:00
abstract::To assess the roles of the low molecular weight heparin (LMWH) on recurrent pregnancy loss (RPL). The relevant studies of all randomized controlled trials (RCTs) were retrieved, and the systematic evaluation was conducted. PubMed, Embase, and Cochrane library databases were searched by using keywords, including low-mo...
journal_title:Taiwanese journal of obstetrics & gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.tjog.2020.11.001
更新日期:2021-01-01 00:00:00