Abstract:
:Sevoflurane concentrations in blood, brain, and lung were measured in an individual apparently dying from sevoflurane inhalation. Sevoflurane is a volatile nonflammable fluorinated methyl isopropyl ether inhaled anesthetic, chemically related to desflurane and isoflurane. The incidence of abuse of sevoflurane is lower than that of other drugs of abuse possibly due to its inaccessibility to the general public and less pleasurable and addicting effects. The dead subject was an anesthetist found prone in bed holding an empty bottle of sevoflurane (Ultane). Serum, urine, and liver were screened for numerous drugs and metabolites using enzyme immunoassays and gas chromatography-mass spectrometry. Analysis did not reveal presence of any drug, including ethanol, other than sevoflurane. Sevoflurane was determined by headspace gas chromatography and revealed concentrations of 15 microg/mL in blood and 130 mg/kg in brain and lung. Autopsy revealed pulmonary edema and frothing in the lung, pathological findings associated with death by sevoflurane or hypoxia. The cause of death was ruled as sevoflurane toxicity and the manner of death as accident.
journal_name
J Forensic Scijournal_title
Journal of forensic sciencesauthors
Rosales CM,Young T,Laster MJ,Eger EI 2nd,Garg Udoi
10.1111/j.1556-4029.2007.00556.xsubject
Has Abstractpub_date
2007-11-01 00:00:00pages
1408-10issue
6eissn
0022-1198issn
1556-4029pii
JFO556journal_volume
52pub_type
杂志文章abstract::Evaluation of an FDA-licensed rapid assay to detect antibodies to human immunodeficiency virus (HIV) was accomplished by testing 414 serum samples collected sequentially from autopsy cases at the Office of the Chief Medical Examiner, State of Maryland. The time of postmortem collection ranged from 8 to 30 hours. All s...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
abstract::A case of apparent suicide by injection of snake venom was investigated. Evidence found at the scene and presumably used for self-injection was positive for nonspecific venom but had the characteristics of a viper venom. ...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract::The current clandestine methodology for the manufacture of illicit cocaine hydrochloride utilizes microwave heating in order to dry the finished product. This study addresses the effects this step has on the occluded solvents present in newly prepared cocaine hydrochloride. Nine 1-kilogram-sized batches of cocaine hyd...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::The aims of this study were to enable geometric morphometric sex classification using tibial proximal and distal sexual dimorphism and to evaluate the secular trend of tibial shape/form from the early 20th century to the present day. The study samples consisted of 61 adult tibias from an early 20th-century Czech popul...
journal_title:Journal of forensic sciences
pub_type: 历史文章,杂志文章
doi:10.1111/1556-4029.12641
更新日期:2015-01-01 00:00:00
abstract::Infants born to diabetic mothers are at increased risk for symptomatic hypoglycemia and death after birth. A 36-year-old G4P3 mother with a history of gestational diabetes and newly diagnosed type II insulin-dependent diabetes gave birth at home, in the care of a midwife, to a macrosomic infant girl (10 lbs.). Several...
journal_title:Journal of forensic sciences
pub_type:
doi:10.1111/1556-4029.14247
更新日期:2020-05-01 00:00:00
abstract::The study presents a method for the demonstration of esophageal varices at autopsy by gastroesophageal phlebography. The veins visible on the radiographs were controlled and evaluated by studying the gross appearance of sections of the esophagus at the level of the varicose veins and by histologic examination of the s...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::The AmpFℓSTR Yfiler PCR Amplification (Yfiler) kit continues to be improved for a better analytical efficiency in cases of highly degraded DNA. The authors endeavored to determine whether coupling of the Yfiler kit with supplemental multiplex amplification of some Y-STR loci is a more efficient analytical mode for poo...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12950
更新日期:2016-03-01 00:00:00
abstract::In this study, we have proposed a novel solvent-based method using a specific concentration of 3M™ Novec™ HFE-72DE and 7200 solvents to untangle duct tape from porous article with minimal impact to the quality of latent fingerprint deposited on the sticky-side surface of duct tape. A series of experiments determined t...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.14146
更新日期:2020-01-01 00:00:00
abstract::Little is known about to what extent the events surrounding death can be reliably reconstructed from blunt force trauma analysis alone. In this study, we reconstruct circumstances of death from a blind blunt force trauma analysis using a sample of 21 individuals of known death circumstances, obtained from two identifi...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.13128
更新日期:2016-11-01 00:00:00
abstract::Little is known about the effect of edaphic conditions on the decomposition of buried mammalian tissues. To address this, we set up a replicated incubation study with three fresh soils of contrasting pH: a Podsol (acidic), a Cambisol (neutral), and a Rendzina (alkaline), in which skeletal muscle tissue (SMT) of known ...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2009.01070.x
更新日期:2009-07-01 00:00:00
abstract::Mitragyna speciosa (MS), a plant commonly known as kratom, is a widely used "legal high" opiate alternative for pain relief. DNA extracted from MS and 26 additional plant species was amplified by PCR using primers targeting the strictosidine beta-D-glucosidase (SGD) and secologanin synthase 2 (SLS2) genes and detected...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.14167
更新日期:2020-01-01 00:00:00
abstract::The association between perpetration of sexual abuse and the offender's own victimization as a child has been well documented in the literature. Various researchers have examined this relationship by assessing the exclusiveness of the sexual abuser's behavior, the gender of his victims and the gender of his own childh...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract::The present study analyzed apical translucency and periodontal recession on single-rooted teeth in order to generate age-at-death estimations using two inverse calibration methods and one Bayesian method. The three age estimates were compared to highlight inherent problems with the inverse calibration methods. The res...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2008.00713.x
更新日期:2008-05-01 00:00:00
abstract::To understand how time and temperature could affect latent fingerprints, wooden pallets were used to construct five units that each housed ten 60-watt incandescent light bulbs. Fingerprints were deposited on the top, middle, and base of the globes. The bulbs were powered on (except the control bulb in each unit) for 1...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.14133
更新日期:2020-01-01 00:00:00
abstract::A 38-year-old man was found in his car suffering from a heart attack. Serum analysis by capillary gas chromatography and mass spectrometry confirmed the presence of dextromoramide (Palfium), methadone, and lidocaine. The serum concentrations at admission to the hospital were: 1.9 micrograms/mL of dextromoramide, 0.4 m...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::While the mitochondrial control region has proven successful for human forensic evaluations by indicating ethnic origin, domestic dogs (Canis lupus familiaris) of seemingly unrelated breeds often form large groups based on identical control region sequences. In an attempt to break up these large haplotype groups, we h...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2008.00952.x
更新日期:2009-03-01 00:00:00
abstract::On request of the International Criminal Tribunal for the former Yugoslavia (ICTY), the Danish-Swedish forensic teams worked in Kosovo during the summer and the fall of 1999. The teams worked mainly as "mobile teams" at sites with few graves. Only two larger sites were examined. Most of the bodies were buried separate...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
abstract::The heme compound found in deoxyribonucleic acid (DNA) extracted from bloodstains, which is regarded as a major inhibitor of polymerase chain reaction (PCR), was characterized in comparison with alkaline and acid hematin, histidine and ammonia hemochromogens, and globin and serum albumin hemochromogens digested by pro...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract::A Scientific Working Group on DNA Analysis Methods (SWGDAM) developmental validation study was carried out on two Y-STR multiplex systems (MPI and MPII) that collectively permit the co-amplification of 19 Y-STR markers, including DYS393, DYS392, DYS391, DYS389I, DYS389II, Y-GATA-A7.2 (DYS461), DYS438, DYS385a and DYS3...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract:POPULATION:The distribution of allele frequencies have been analyzed at two short tandem repeat (STR) loci FES and D2S1328 among five anthropologically distinct ethnic groups of India namely Ezhavas, Nairs, Arayas, Vishwakarma and Muslims. Muslims are religio-ethnic group while other populations mentioned above belong ...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:2004-03-01 00:00:00
abstract::To minimize bias by the testifying clinician, particularly in professional liability cases, six practical measures should be used: 1. testify for both the plaintiff and the defense in different cases; 2. assess the merits of the case separately from agreeing to testify; 3. insist on reviewing all the records thoroughl...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract::A population of persons who were found, at death, to have significant levels of isopropyl alcohol (isopropanol) in their blood is described. The role of isopropanol in causing death is reviewed in 57 fatal cases. The contribution of acetone, the major metabolite of isopropanol, to death is assessed. Results indicate t...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1982-07-01 00:00:00
abstract::Complete or incomplete decapitation as a consequence of suicidal hanging is very rare, few cases having been reported in the worldwide literature. Posthanging decapitation is typically related to a drop of several meters. Three cases of complete decapitation and one case of incomplete decapitation by suicidal hanging ...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12001
更新日期:2013-01-01 00:00:00
abstract::Classification of ignitable liquids in accordance with voluntary consensus-based standards published by ASTM International has become increasingly specific, relying upon both the chemical composition and the boiling point range of submitted ignitable liquids. This classification system includes among others, specific ...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract::Renal cortical pallor was studied as a potential marker at autopsy of diabetic ketoacidosis in 23 cases, hyperglycemic nonketotic coma in eight cases, and alcoholic ketoacidosis in five cases (vitreous humor glucose level≥11.1 mM; β-hydroxybutyrate level≥5 mM). Renal cortical pallor was noted on macroscopic examinatio...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12102
更新日期:2013-05-01 00:00:00
abstract::Acid scavengers are frequently used as stabilizer compounds in a variety of applications. When used to stabilize volatile compounds such as nerve agents, the lower volatility and higher stability of acid scavengers make them more persistent in a post-event forensic setting. Compound-specific isotope analysis of carbon...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2011.01959.x
更新日期:2012-01-01 00:00:00
abstract::Intercostal and age differences in the sternal rib end morphology of documented female skeletons from Spitalfields and St. Bride's are examined. The morphology was captured using three-dimensional morphometrics and the statistical analyses employed included parametric and nonparametric MANOVA, discriminant analysis, a...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/1556-4029.12047
更新日期:2013-03-01 00:00:00
abstract::Fluids from frozen muscle tissue taken from 449 white-tailed deer (Odocoileus virginianus) were analyzed using a radioimmunoassay technique for testosterone. Comparing 309 deer sampled in early November, antlered males had significantly higher tissue testosterone levels (range = 0.18 to 16.00 ng/mL) than females (rang...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1986-07-01 00:00:00
abstract::Unavailable in the literature is any reference to an investigation of death after evidence has been destroyed. In this presentation two firearms and the bullet were melted after the death was certified as a suicide. A team of investigators conducted a psychological autopsy as well as shot patterns to determine the dis...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::The Johns Hopkins University Center for Craniofacial Development and Disorders estimates that 1 in 3,000 children born in the United States is diagnosed with a rare form of craniosynostosis. Although the medical literature has documented numerous descriptions of craniofacial disorders from an anthropometric or genetic...
journal_title:Journal of forensic sciences
pub_type: 杂志文章
doi:10.1111/j.1556-4029.2008.00872.x
更新日期:2008-11-01 00:00:00