Abstract：
:Predicting the chromosomal location of mapped markers has been difficult because linkage maps do not reveal differences in crossover frequencies along the physical structure of chromosomes. Here we combine a physical crossover map based on the distribution of recombination nodules (RNs) on Solanum lycopersicum (tomato) synaptonemal complex 1 with a molecular genetic linkage map from the interspecific hybrid S. lycopersicum x S. pennellii to predict the physical locations of 17 mapped loci on tomato pachytene chromosome 1. Except for one marker located in heterochromatin, the predicted locations agree well with the observed locations determined by fluorescence in situ hybridization. One advantage of this approach is that once the RN distribution has been determined, the chromosomal location of any mapped locus (current or future) can be predicted with a high level of confidence.
journal_name
Geneticsjournal_title
Geneticsauthors
Chang SB,Anderson LK,Sherman JD,Royer SM,Stack SMdoi
10.1534/genetics.107.074138subject
Has Abstractpub_date
2007-08-01 00:00:00pages
2131-8issue
4eissn
0016-6731issn
1943-2631pii
genetics.107.074138journal_volume
176pub_type
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