Decision analysis of medical and surgical treatments for trigeminal neuralgia: how patient evaluations of benefits and risks affect the utility of treatment decisions.

abstract：:It is well known that acupuncture has pain-relieving effects, but the contribution of specific and especially nonspecific factors to acupuncture analgesia is less clear. One hundred one patients who developed pain of ≥ 3 on a visual analog scale (VAS, 0 to 10) after third molar surgery were randomized to receive activ...

journal_title：Pain

authors： Vase L,Baram S,Takakura N,Yajima H,Takayama M,Kaptchuk TJ,Schou S,Jensen TS,Zachariae R,Svensson P

更新日期：2013-09-01 00:00:00

abstract：:Metastatic bone cancer causes severe pain that is primarily treated with opioids. A model of bone cancer pain in which the progression of cancer pain and bone destruction is tightly controlled was used to evaluate the effects of sustained morphine treatment. In cancer-treated mice, morphine enhanced, rather than dimin...

journal_title：Pain

authors： King T,Vardanyan A,Majuta L,Melemedjian O,Nagle R,Cress AE,Vanderah TW,Lai J,Porreca F

更新日期：2007-11-01 00:00:00

abstract：:In previous studies we demonstrated that protein kinase D1 (PKD1/PKCmu) could directly phosphorylate the transient receptor potential V1 (TRPV1) at its N-terminal region and enhance the function of TRPV1 in CHO cells stably transfected with TRPV1. In the current study we assessed the involvement of PKD1 in pain modula...

journal_title：Pain

authors： Zhu H,Yang Y,Zhang H,Han Y,Li Y,Zhang Y,Yin D,He Q,Zhao Z,Blumberg PM,Han J,Wang Y

更新日期：2008-07-31 00:00:00

abstract：:Return of sensory nerve function in rat molars following cut or crush injury to the inferior alveolar nerve (IAN) was measured by observing the jaw opening reflex (JOR) response of the digastric muscle to electrical stimulation of individual molars or the gingiva. The IAN was injured from a lateral approach to the man...

journal_title：Pain

authors： Berger RL,Byers MR,Calkins DF

更新日期：1983-04-01 00:00:00

abstract：:Long-term potentiation (LTP) in wide dynamic range (WDR) neurons in the dorsal horn has been suggested to contribute to central sensitization and the development of chronic pain. Indirect experimental evidence indicates an involvement of substance P (SP), in this respect. The aim of the present study was to monitor th...

journal_title：Pain

authors： Afrah AW,Fiskå A,Gjerstad J,Gustafsson H,Tjølsen A,Olgart L,Stiller CO,Hole K,Brodin E

更新日期：2002-03-01 00:00:00

abstract：:The present paper presents the relationship between the total body-pain (TBP) score, defined as the total number of areas shaded on a pain drawing, and the pain from one area, the Shoulder-Neck (SN), among subjects in or out of full-time gainful work respectively. Furthermore, relationships between pain-score, self-ex...

journal_title：Pain

authors： Ektor-Andersen J,Isacsson SO,Lindgren A,Ørbæk P,Malmö Shoulder-Neck Study group.

更新日期：1999-09-01 00:00:00

abstract：:Opiate-adrenergic interactions were investigated by studying the effect of the selective alpha 2-adrenergic agonist, clonidine, on the analgesia produced by intravenous placebo and by the predominantly kappa-opiate agonist, pentazocine, in patients with dental postoperative pain. Clonidine did not affect the pain leve...

journal_title：Pain

authors： Gordon NC,Heller PH,Levine JD

更新日期：1992-02-01 00:00:00

abstract：:Investigating protective strategies against chronic neuropathic pain (CNP) after breast cancer surgery entails using valid screening tools. The DN4 (Douleur Neuropathique en 4 questions) is 1 tool that offers important research advantages. This prospective 6-month follow-up study seeks to validate the DN4 and assess i...

journal_title：Pain

authors： Abdallah FW,Morgan PJ,Cil T,Escallon JM,Semple JL,Chan VW

更新日期：2015-04-01 00:00:00

abstract：:Neuroimaging studies of patients with chronic pain have shown that neurotransmitter abnormalities, including increases in glutamate and decreases in GABA, could be responsible for the cortical hyperactivity and hyperalgesia/allodynia observed in some pain conditions. These finding are particularly evident in the insul...

journal_title：Pain

authors： Watson CJ

更新日期：2016-10-01 00:00:00

abstract：:Disabling neuropathic pain (NeuP) is a common sequel of diabetic peripheral neuropathy (DPN). We aimed to characterise the sensory phenotype of patients with and without NeuP, assess screening tools for NeuP, and relate DPN severity to NeuP. The Pain in Neuropathy Study (PiNS) is an observational cross-sectional multi...

journal_title：Pain

authors： Themistocleous AC,Ramirez JD,Shillo PR,Lees JG,Selvarajah D,Orengo C,Tesfaye S,Rice ASC,Bennett DLH

更新日期：2016-05-01 00:00:00

abstract：:Morphine is widely used to treat severe pain in neonatal intensive care unit patients. Animal studies suggest adverse long-term side effects of neonatal morphine, but a follow-up study of 5-year-old children who participated in a morphine-placebo controlled trial as newborns found no such effects on the child's genera...

journal_title：Pain

authors： de Graaf J,van Lingen RA,Valkenburg AJ,Weisglas-Kuperus N,Jebbink LG,Wijnberg-Williams B,Anand KJS,Tibboel D,van Dijk M

更新日期：2013-03-01 00:00:00

abstract：:Many malignant cancers, including breast cancer, have a propensity to invade bones, leading to excruciating bone pain. Opioids are the primary analgesics used to alleviate this cancer-induced bone pain (CIBP) but are associated with numerous severe side effects, including enhanced bone degradation, which significantly...

journal_title：Pain

authors： Zhang H,Lund DM,Ciccone HA,Staatz WD,Ibrahim MM,Largent-Milnes TM,Seltzman HH,Spigelman I,Vanderah TW

更新日期：2018-09-01 00:00:00

abstract：:The present study examined the role of catastrophizing in predicting levels of pain and disability in a sample of individuals who had sustained soft-tissue injuries to the neck, shoulders or back following work or motor vehicle accidents. Participants were 86 (27 men, 59 women) consecutive referrals to the Atlantic Pa...

journal_title：Pain

authors： Sullivan MJL,Stanish W,Waite H,Sullivan M,Tripp DA

更新日期：1998-09-01 00:00:00

abstract：:Experimental data have suggested that in neuropathic pain, tricyclic antidepressants may work solely through a β2-agonist action. The aim of this study was to test if the β2-agonist terbutaline relieves painful polyneuropathy. The study was a randomized, double-blind, placebo-controlled and active-controlled, 3-way, c...

journal_title：Pain

authors： Gillving M,Demant D,Holbech JV,Gylfadottir SS,Bach FW,Jensen TS,Finnerup NB,Sindrup SH

更新日期：2020-11-06 00:00:00

abstract：:Studies on the efficacy of ketamine in the treatment of chronic pain indicate that prolonged or repetitive infusions are required to ensure prolonged pain relief. Few studies address ketamine-induced toxicity. Here we present data on the occurrence of ketamine-induced liver injury during repeated administrations of S(...

journal_title：Pain

authors： Noppers IM,Niesters M,Aarts LPHJ,Bauer MCR,Drewes AM,Dahan A,Sarton EY

更新日期：2011-09-01 00:00:00

abstract：:Postmastectomy pain (PMP), a distinctive postsurgical neuropathic pain syndrome, has been thought to be consequence of 4-6% of surgical procedures for cancer of the breast, but remains understudied and poorly documented. In this cross-sectional descriptive study, a convenience sample of 95 women who had undergone brea...

journal_title：Pain

authors： Stevens PE,Dibble SL,Miaskowski C

更新日期：1995-04-01 00:00:00

abstract：:Pain has the capacity to interfere with daily tasks. Although task interference by pain is largely unintentional, it can be controlled to a certain extent. Such top-down control over pain has been believed to be reduced in patients with fibromyalgia (FM). In this study, we investigated task interference and distractio...

journal_title：Pain

authors： Van Ryckeghem DML,Rost S,Kissi A,Vögele C,Crombez G

更新日期：2018-06-01 00:00:00

abstract：ABSTRACT:The burden of pain in newborn infants has been investigated in numerous studies, but little is known about the appropriateness of the use of pain scales according to the specific type of pain or infant condition. This systematic review aimed to evaluate the reporting of neonatal pain scales in randomized trial...

journal_title：Pain

authors： Olsson E,Ahl H,Bengtsson K,Vejayaram DN,Norman E,Bruschettini M,Eriksson M

更新日期：2021-02-01 00:00:00

abstract：:Numerous behavioral pain measures have been validated for young children, but none is appropriate to assess pain in emergency departments (EDs), where caregivers need a simple, easily completed scale. Our objective was to elaborate and validate a tool, relevant in any painful situation, with agitation or prostration, ...

journal_title：Pain

authors： Fournier-Charrière E,Tourniaire B,Carbajal R,Cimerman P,Lassauge F,Ricard C,Reiter F,Turquin P,Lombart B,Letierce A,Falissard B

更新日期：2012-08-01 00:00:00

abstract：:The opiate antagonist naloxone has been reported to cause pain relief. Therefore, the effect was determined of naloxone, injected intravenously, on the activity in single neurones of the dorsomedial part of the ventral nucleus (VDM) in the thalamus of rats under urethane anaesthesia elicited by electrical stimulation ...

journal_title：Pain

authors： Jurna I

更新日期：1988-12-01 00:00:00

abstract：:The aim of this study was to investigate how exercise influenced endogenous pain modulation in healthy controls, shoulder myalgia patients and fibromyalgia (FM) patients. Twenty-one healthy subjects, 20 shoulder myalgia patients and 20 FM patients, all females, participated. They performed standardized static contract...

journal_title：Pain

authors： Lannersten L,Kosek E

更新日期：2010-10-01 00:00:00

abstract：:The blood vessels and the pial surface of the brain, spinal cord and its roots are innervated by primary afferent neurones. Here, we have electrophysiologically characterized the functional properties of a subpopulation of these afferent fibres that supply the ventral roots of the cat sacral spinal cord. We have taken...

journal_title：Pain

authors： Jänig W,Koltzenburg M

更新日期：1991-04-01 00:00:00

abstract：:A young female outpatient experienced painful tonic contractions in the right triceps surae muscles as a result of a partial damage of the right peroneal nerve. Electrophysiological recordings of the soleus muscle showed a tonic EMG activity and an hyperexcitability of the monosynaptic H reflex (Hmax/Mmax ratio: 90%)....

journal_title：Pain

authors： Wilier JC

更新日期：1988-03-01 00:00:00

abstract：:A preliminary report of clinical study revealed that chronic discogenic low back pain could be treated by intradiscal methylene blue (MB) injection. We investigated the effect of intradiscal MB injection for the treatment of chronic discogenic low back pain in a randomized placebo-controlled trial. We recruited 136 pa...

journal_title：Pain

authors： Peng B,Pang X,Wu Y,Zhao C,Song X

更新日期：2010-04-01 00:00:00

abstract：:This study investigated the role of TRPA1 in the development and maintenance of mechanical and cold hyperalgesia in persistent inflammation induced by Complete Freund's Adjuvant (CFA) in mice. The intraplantar (i.pl.) injection of CFA induced a long lasting (28 days) hyperalgesia for both mechanical and thermal (cold)...

journal_title：Pain

authors： da Costa DSM,Meotti FC,Andrade EL,Leal PC,Motta EM,Calixto JB

更新日期：2010-03-01 00:00:00

abstract：:Individuals diagnosed with fibromyalgia syndrome (FMS) report chronic pain that is frequently worsened by physical activity and improved by rest. Palpation of muscle and tendinous structures suggests that nociceptors in deep tissues are abnormally sensitive in FMS, but methods of controlled mechanical stimulation of m...

journal_title：Pain

authors： Staud R,Cannon RC,Mauderli AP,Robinson ME,Price DD,Vierck CJ Jr

更新日期：2003-03-01 00:00:00

abstract：:We propose a blade as a noninjurious nociceptive stimulus modeling sharp mechanical pain and yielding acute pain and hyperalgesia responses with closer proximity to incision-induced pain/hyperalgesia than punctate or blunt pressure mechanical pain models. Twenty-six healthy men and women were investigated to compare a...

journal_title：Pain

authors： Shabes P,Schloss N,Magerl W,Schmahl C,Treede RD,Baumgärtner U

更新日期：2016-01-01 00:00:00

abstract：:Measuring health complaints by administrating a single report is common. Our aim was to assess variation in pain and other subjective complaints over an extended period, whether a single-sample produces representative data, and determine associations between complaints. Health-complaint reports were collected from pos...

journal_title：Pain

authors： Steingrímsdóttir OA,Vøllestad NK,Røe C,Knardahl S

更新日期：2004-07-01 00:00:00

abstract：:Experimental muscle pain was elicited by bolus injection of 0.15 ml of 5% hypertonic saline into the human masseter muscle. The sensory experience was described using 10-cm visual analogue scales (VAS) and the McGill Pain Questionnaires (MPQ) on 10 subjects. Effects of pain on deliberately unilateral mastication were ...

journal_title：Pain

authors： Svensson P,Arendt-Nielsen L,Houe L

更新日期：1996-02-01 00:00:00

abstract：:Chronic pain after tissue trauma is frequent and may have a lasting impact on the functioning and quality of life of the affected person. Despite this, chronic postsurgical and posttraumatic pain is underrecognised and, consequently, undertreated. It is not represented in the current International Classification of Di...

journal_title：Pain

authors： Schug SA,Lavand'homme P,Barke A,Korwisi B,Rief W,Treede RD,IASP Taskforce for the Classification of Chronic Pain.

更新日期：2019-01-01 00:00:00