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Lithium, arginine vasopressin and the dex/CRH test in mood disordered patients.

Abstract：

:The impact of lithium on arginine vasopressin (AVP) release has implications for our understanding of the pathophysiology and treatment of mood disorders and for the interpretation of neuroendocrine studies. In this secondary analysis of neuroendocrine, data from 23 patients with chronic major depressive disorder, 41 patients with bipolar disorder and 18 healthy controls, we examine the relationship between lithium therapy, AVP levels and the cortisol response to the dexamethasone/corticotropin-releasing hormone (dex/CRH) test. These data demonstrate that patients taking lithium have elevated post-dexamethasone AVP levels compared to both healthy controls and patients not on lithium.

journal_name

Psychoneuroendocrinology

journal_title

Psychoneuroendocrinology

authors

Watson S,Gallagher P,Smith MS,Young AH,Ferrier IN

doi

10.1016/j.psyneuen.2007.02.010

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

464-9

issue

5

eissn

0306-4530

issn

1873-3360

pii

S0306-4530(07)00053-4

journal_volume

32

pub_type

临床试验,杂志文章

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