Abstract:
OBJECTIVES:The aim of this prospective study was to compare the diagnostic accuracy of detrusor wall thickness (DWT), free uroflowmetry, postvoid residual urine, and prostate volume (index tests) with pressure-flow studies (reference standard) to detect bladder outlet obstruction (BOO) in men. METHODS:During a 2-yr period, men older than 40 yr with lower urinary tract symptoms and/or prostatic enlargement had the following tests: ultrasound measurements of DWT, free uroflowmetry (Q(max), Q(ave)), postvoid residual urine, and prostate volume. Pressure-flow studies were used to divide obstructed from nonobstructed bladders. RESULTS:One hundred sixty men between 40-89 yr of age (median: 62 yr) were included in the study; 75 patients (46.9%) had BOO according to pressure-flow studies. The results of all investigated index tests differed significantly between obstructed and nonobstructed men. DWT was the most accurate test to determine BOO: the positive predictive value was 94%, specificity 95%, and the area under the curve of ROC analysis 0.93. There was an agreement of 89% between the results of DWT measurement and pressure-flow studies. CONCLUSIONS:Measurements of DWT can detect BOO better than free uroflowmetry, postvoid residual urine, or prostate volume. In clinical routine, DWT measurements can be used to judge BOO noninvasively.
journal_name
Eur Uroljournal_title
European urologyauthors
Oelke M,Höfner K,Jonas U,de la Rosette JJ,Ubbink DT,Wijkstra Hdoi
10.1016/j.eururo.2006.12.023subject
Has Abstractpub_date
2007-09-01 00:00:00pages
827-34issue
3eissn
0302-2838issn
1873-7560pii
S0302-2838(06)01605-8journal_volume
52pub_type
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