Abstract:
:Much attention has been devoted in the past to monitor changes of mobile lipid (ML) (1)H MRS signals in spectra of tumour cells. The purpose of this work is to exploit ML signals to provide information on cell metabolism after irradiation, comparing tumour cells characterised by different radiosensitivity and relating MRS findings to changes in cell proliferation and delays in cell cycle phases. Irradiated HeLa cells present less intense ML signals with respect to controls. The opposite is true for MCF-7 cells. A G(2) arrest is observed for both cell lines after irradiation. In HeLa cells, G(1) decreases and S phase is maintained; a sub G(1) peak is also visible. In MCF-7 cells, G(1) is decreased and S phase is strongly reduced, while no sub G(1) is present. The observed changes in ML are tentatively associated to cell cycle regulation of phospholipid synthesis. Mathematical modelling of ML variations is in progress.
journal_name
Radiat Prot Dosimetryjournal_title
Radiation protection dosimetryauthors
Grande S,Giovannini C,Luciani AM,Palma A,Rosi A,Sapora O,Viti V,Guidoni Ldoi
10.1093/rpd/ncl517subject
Has Abstractpub_date
2006-01-01 00:00:00pages
202-4issue
1-4eissn
0144-8420issn
1742-3406pii
ncl517journal_volume
122pub_type
杂志文章abstract::The dosimetric use of the chemical solution chlorobenzene-ethanol-trimethylpentane (CET) is based on the radiolytic formation of hydrochloric acid, which protonates a pH indicator thymolsulphonphthalein. On the basis of the CET solution, an accident and emergency personal dosemeter was designed allowing doses in the r...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncm042
更新日期:2007-01-01 00:00:00
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journal_title:Radiation protection dosimetry
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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abstract::A single-parameter geometry to describe soil is achieved for Monte Carlo calculation of absorbed dose rate in air for photon emitters from natural radionuclides. This optimised geometry based on physical assumptions consists of the soil part whose emitted radiation has a given minimum probability to reach the detector...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncm426
更新日期:2008-01-01 00:00:00
abstract::Owing to the introduction of new diagnostic procedures, such as computed tomography (CT), positron emission tomography (PET) and single photon emission computed tomography (SPECT), the individual dose caused by medical exposures has grown rapidly in the last years. This is especially a subject to radiation protection ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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更新日期:2010-04-01 00:00:00
abstract::During the 7th European Conference on Protection Against Radon at Home and at Work held in the autumn of 2013 in Prague, the second intercomparison of measuring instruments for radon and its short-lived decay products and the first intercomparison of radon/thoron gas discriminative passive detectors in mix field of ra...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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更新日期:2014-07-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncs285
更新日期:2013-02-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncr229
更新日期:2012-04-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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更新日期:2019-10-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006324
更新日期:2003-01-01 00:00:00
abstract::The occupational radiation exposure of medical radiation workers at the Institute of Oncology, Vilnius University (IOVU) was analysed. Quartile dose measurements were collected and routinely analysed for a period of 8 y from 1 January 2004 to 31 December 2011. A total of 193 medical radiation workers were monitored, c...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nct111
更新日期:2013-11-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncy254
更新日期:2019-05-01 00:00:00
abstract::Despite wide use of nuclear energy and radiation sources in industry and medicine, there is no centralised dose accounting system in Ukraine; existing dosimetry services operate obsolete manual thermoluminescence dosemeter (TLD) readers and do not meet modern proficiency standards. Currently, dosimetric monitoring is ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncl128
更新日期:2007-01-01 00:00:00
abstract::The results of large-scale computed tomography (CT) patient dose surveys from the USA, UK and Germany undertaken during the period 1999-2001 were reviewed. The mean values for volume-weighted CT dose index (CTDI(vol)) and dose length product (DLP) were extracted. For head CT examinations, the reported values for the t...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncs123
更新日期:2013-01-01 00:00:00
abstract::The time variation of the radon equilibrium factor F was measured every four hours in the Nuclear Technology Laboratory of the Aristotle University of Thessaloniki (in northern Greece) during October 1998-April 1999. The time dependence of the mean weekly value of radon equilibrium factor F is relatively small. During...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006143
更新日期:2003-01-01 00:00:00
abstract::This study aims to provide more insight in attenuation characteristics and corresponding lead (Pb) equivalences of a broad range of commercially available lead composite and nonlead protective garments. Thirty garments of five manufacturers (listed as 0.25-0.35-0.50 mm Pb equivalent) were tested. Transmission values w...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncw373
更新日期:2017-08-01 00:00:00
abstract::A dose evaluation method for neutrons in the energy range of a few MeV to 100 MeV has been developed using a spectrum weight function (G-function), which is applied to an organic liquid scintillator of 12.7 cm in diameter and 12.7 cm in length. The G-function that converts the pulse height spectrum of the scintillator...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006071
更新日期:2002-01-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncaa200
更新日期:2020-12-17 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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更新日期:2011-05-01 00:00:00
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journal_title:Radiation protection dosimetry
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更新日期:2008-01-01 00:00:00
abstract::Between 1952 and 1957, the UK exploded a total of 12 nuclear devices in Australia, and also conducted about 600 'minor trials' that did not involve a nuclear explosion. Over 16 000 Australian servicemen and civilians were involved in the UK tests in Australia. This paper reports the estimation of doses that the Austra...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncp164
更新日期:2009-09-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq491
更新日期:2011-03-01 00:00:00
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nci627
更新日期:2006-01-01 00:00:00
abstract::An automatic measuring apparatus called exhalometer for measurement of the radon exhalation rate from soil is introduced. It consists of a pneumatic driven accumulation chamber with an open bottom, a PC-based control system, six Lucas cells for radon measurement and sensors for environmental parameters. It allows movi...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncx165
更新日期:2017-11-01 00:00:00
abstract::An extensive studies on the indoor activity concentrations of thoron, radon and their progeny in the granite region in the state of Karnataka, India, has been carried out since, 2007 in the scope of a lung cancer epidemiological study using solid-state nuclear track detector-based double-chamber dosemeters (LR-115, ty...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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更新日期:2014-03-01 00:00:00
abstract::The purpose of the research is to develop an integrated technique for determining the effective dose (E) of external and internal exposure by different sources of ionizing radiation. The proposing technique for determining the total effective dose is based on three methods of calculation. The first one is multiplying ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncz170
更新日期:2019-12-31 00:00:00
abstract::The World Health Organization (WHO), the International Commission on Non-Ionizing Radiation Protection (ICNIRP), WHO's scientific collaborating centres (including the UK's National Radiological Protection Board (NRPB)) and over 50 participating Member States are participants of WHO's International EMF Project. As part...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006363
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journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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更新日期:2010-12-01 00:00:00
abstract::Composite neutron scintillators consisting of neutron-insensitive fluorescent dopant particles (e.g. ZnS:Ag) embedded in a matrix material containing isotopes with high neutron cross sections that emit energetic charged particles (e.g. 6Li) are a popular method for neutron detection in a variety of applications. The s...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
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更新日期:2005-01-01 00:00:00