Abstract:
:Much attention has been devoted in the past to monitor changes of mobile lipid (ML) (1)H MRS signals in spectra of tumour cells. The purpose of this work is to exploit ML signals to provide information on cell metabolism after irradiation, comparing tumour cells characterised by different radiosensitivity and relating MRS findings to changes in cell proliferation and delays in cell cycle phases. Irradiated HeLa cells present less intense ML signals with respect to controls. The opposite is true for MCF-7 cells. A G(2) arrest is observed for both cell lines after irradiation. In HeLa cells, G(1) decreases and S phase is maintained; a sub G(1) peak is also visible. In MCF-7 cells, G(1) is decreased and S phase is strongly reduced, while no sub G(1) is present. The observed changes in ML are tentatively associated to cell cycle regulation of phospholipid synthesis. Mathematical modelling of ML variations is in progress.
journal_name
Radiat Prot Dosimetryjournal_title
Radiation protection dosimetryauthors
Grande S,Giovannini C,Luciani AM,Palma A,Rosi A,Sapora O,Viti V,Guidoni Ldoi
10.1093/rpd/ncl517subject
Has Abstractpub_date
2006-01-01 00:00:00pages
202-4issue
1-4eissn
0144-8420issn
1742-3406pii
ncl517journal_volume
122pub_type
杂志文章abstract::A model of radiation-induced bystander effects is presented that explicitly takes into account the transient nature of bystander signal emission post-irradiation, signal lifetime and the non-linear cellular response to the signals. Data are analysed on mutagenesis induced in human lymphoblasts in medium transfer exper...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv170
更新日期:2015-09-01 00:00:00
abstract::A theoretical study was carried out to re-evaluate the integrity of the biological shielding of (137)Cs brachytherapy unit at the Korle Bu Teaching Hospital, Ghana, and the results were verified by measurement of the dose rates at selected locations. The primary objective was to determine the current state of protecti...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq001
更新日期:2010-06-01 00:00:00
abstract::Radon diffusion coefficient is a material parameter which is usually used in the radon mitigation measures design. There are different approaches used for radon diffusion coefficient measurement and assessment. The International comparison measurement which was jointly organised by National Radiation Protection Instit...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncr079
更新日期:2011-05-01 00:00:00
abstract::According to the worldwide reports, industrial radiography is one of the highest risk radiation practices due to handling high activity sources. Therefore, an optimization of protection along with appropriate investigation level and/or dose constraint is required to achieve appropriate radiological safety. This resear...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncy021
更新日期:2018-10-01 00:00:00
abstract::Biokinetic models are the scientific underpinning of internal dosimetry and depend, ultimately, for their scientific validation on comparisons with human bioassay data. Three significant plutonium/americium bioassay databases, known to the authors, are described: (1) Sellafield, (2) Los Alamos and (3) the United State...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncm164
更新日期:2007-01-01 00:00:00
abstract::The purpose of this paper is to evaluate the image quality and dose to patients in the radiography of sacroiliac joints and to perform a clinical comparative study of digital and conventional screen-film radiography. Routine radiography of sacroiliac joint was performed in 60 patients using digital and screen-film rad...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncs315
更新日期:2013-06-01 00:00:00
abstract::238U, 234U and 235U were determined in tap water from municipal water pipes that drew their supply from surface water or ground water in various locations in Poland. Average activity concentrations of 238U, 234U and 235U in tap water from surface water were 9.6 +/- 7.1, 12.8 +/- 9.7 and 0.41 +/- 0.31 Bq m(-3), respect...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nch425
更新日期:2005-01-01 00:00:00
abstract::In order to provide reference fields for the ionising radiation, PTB operates the ion accelerator facility. Referring to high energy photons, reference fields according to International Organization for Standardization 4037 series are produced. The neutron component of the 6-7 MeV photon field (R-F), which is produced...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncp101
更新日期:2009-07-01 00:00:00
abstract::In Russia, especially in big cities like St. Petersburg, the annual number of interventional radiological (IR) examinations for both diagnostic and treatment purposes is increasing continuously. However, IR examinations might involve high patient doses and even the risk of skin injures that should be prevented. In thi...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章,多中心研究
doi:10.1093/rpd/ncq021
更新日期:2010-04-01 00:00:00
abstract::Neutron survey instruments have been exposed at all the measurement locations used in the EVIDOS project. These results have an important impact in the interpretation of the results from the project, since operationally the survey instrument will be used for an initial assessment of and routine monitoring of the ambie...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncm160
更新日期:2007-01-01 00:00:00
abstract::The International Atomic Energy Agency (IAEA) through the International Action Plan on Radiation Protection of Patients and the International Commission on Radiological Protection have for some time carried out important efforts to assure that in the medical applications of the ionising radiations, the optimisation of...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nct069
更新日期:2013-09-01 00:00:00
abstract::There are several occurrences of thermal waters in the south-eastern part of Serbia, which are originating from igneous and metamorphic rocks. These waters are mainly used in balneology, but some of them are used for drinking purposes and in water supply to heat buildings, for greenhouses and to irrigate land. In this...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncu094
更新日期:2014-07-01 00:00:00
abstract::Tissue-equivalent proportional counters (TEPCs) are widely used in experimental microdosimetry for characterising the radiation quality in radiation protection and radiation therapy environments. Generally, TEPCs are filled with tissue-equivalent gas mixtures, at low gas pressure, to simulate tissue site sizes similar...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/nct248
更新日期:2014-10-01 00:00:00
abstract::The individual monitoring service at the Helmholtz Zentrum München is currently developing a new eye lens dosemeter to be integrated in radiation protection glasses and a new ring dosemeter using a new BeOSL detector element for extremity dosimetry developed by Dosimetrics. In the design process for the new eye lens d...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncy299
更新日期:2019-12-23 00:00:00
abstract::A neutron spectrometry and dosimetry measurement system has been developed based on a different design of the divided regions for a sphere, with three position-sensitive counters. The characteristics of the measurement system have been investigated in the reference radiation fields of Am-Be and (252)Cf sources. When r...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncl077
更新日期:2007-01-01 00:00:00
abstract::This paper presents the values of radon and thoron progeny concentrations for different seasons in the dwellings of Tehri Garhwal, India. The measurements have been carried out using LR-115 solid-state nuclear track detector-based passive time-integrated direct thoron progeny sensor/direct radon progeny sensor techniq...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv224
更新日期:2015-11-01 00:00:00
abstract::The study of spatial distribution of the indoor radon has assumed in the last years a lot of interest. The geostatistical techniques turn out to be particularly promising. The present work presents the results of a study where around 4000 indoor radon data from Veneto, Friuli Venezia-Giulia and Alto Adige, collected d...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncp252
更新日期:2009-12-01 00:00:00
abstract::Theoretical models to calculate the indoor gamma and radon doses are reviewed, refined and applied. The model for gamma doses is built based on the relative effects of the different room elements that control the amount of radiation. The relative doses are calculated by the MCNP5 simulation software. The gamma sources...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章,评审
doi:10.1093/rpd/ncz008
更新日期:2019-12-31 00:00:00
abstract::The design and dosimetry of a novel in vitro radon irradiation facility to investigate cytogenetic damage induced by radon and progeny is described. The system offers a 4pi geometry for uniform irradiation, proving a versatile and convenient facility for irradiation of whole blood cells in suspension or media. Doses c...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncn060
更新日期:2008-01-01 00:00:00
abstract::The rigorous characterisation of the behaviour of a radiobase antenna for wireless communication systems is a hot topic both for antenna or communication system design and for radioprotection-hazard reasons. Such a characterisation deserves a numerical solution, and the use of a finite-difference time-domain (FD-TD) a...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006699
更新日期:2001-01-01 00:00:00
abstract::This paper presents an efficient algorithm for estimating the unknown emission rate of radionuclides in the atmosphere following a nuclear accident. The algorithm is based on assimilation of gamma dose rate measured data in a Lagrangian atmospheric dispersion model. Such models are used in the framework of nuclear eme...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq592
更新日期:2012-01-01 00:00:00
abstract::Lignite burning is one of the sources of technologically enhanced exposure to humans from natural radionuclides. In the preliminary study, part of the survey, the activity concentrations of (226)Ra, (232)Th and (40)K in 112 samples of feed lignites from seven lignite-fired power plants in Western Anatolia (Seyitömer, ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncq210
更新日期:2010-12-01 00:00:00
abstract::The enhancing effect due to long-time irrigation with radium-containing groundwater on soil was investigated in this work. Samples from the Al-Qassim and Hail areas in Saudi Arabia were studied for their 226Ra and 228Ra inventories. Groundwater and soil samples were collected from 32 farms where agricultural activitie...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncz287
更新日期:2020-06-24 00:00:00
abstract::Multi-element thermoluminescence dosemeters (TLD), such as the Panasonic UD-809, are used in personal dosimetry. The Panasonic UD-809 dosemeter consists of one gamma sensitive and three neutron sensitive TLD elements with different filter materials. In this work, the neutron energy responses (the number of (n,alpha) r...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006517
更新日期:2001-01-01 00:00:00
abstract::Magnetic resonance imaging (MRI) is one of the most common sources of electromagnetic (EM) fields as a diagnostic technique widely used in medicine. MRI staff during the working day is constantly exposed to static and spatially heterogeneous magnetic field. Also, moving around the MRI room to perform their functions, ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncy114
更新日期:2018-12-01 00:00:00
abstract::An autonomous unmanned helicopter (AUH) survey is a useful tool for monitoring the distribution of ambient dose equivalent rates. However, the AUH survey method was developed for plane permeable fields such as agricultural land, and its applicability to urban areas is unclear. In this study, the applicability was inve...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncz116
更新日期:2019-10-01 00:00:00
abstract::The focus of nuclear emergency planning in Austria has been so far on mitigating effects of widespread contamination (e.g. after NPP accidents); however, these plans did not contain provisions on the medical management of an acute radiation syndrome. To close this gap, a 'Medical Radiation Emergency Plan' was created ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncw210
更新日期:2016-09-01 00:00:00
abstract::The results of large-scale computed tomography (CT) patient dose surveys from the USA, UK and Germany undertaken during the period 1999-2001 were reviewed. The mean values for volume-weighted CT dose index (CTDI(vol)) and dose length product (DLP) were extracted. For head CT examinations, the reported values for the t...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncs123
更新日期:2013-01-01 00:00:00
abstract::This paper proposes a method for evaluating the standard uncertainty in the measurements with passive personal dosemeters using a numerical method (Monte Carlo). The paper builds on a previous paper where a two-stage measurement model for passive dosemeters was proposed. This model follows the course of events during ...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/rpd/ncv493
更新日期:2016-09-01 00:00:00
abstract::The W values of protons in water vapour were measured for energies from 1 keV to 100 keV with uncertainties lower than 1%. To study the energy and phase dependence of W values, the W values of protons in water vapour and liquid water were calculated for energies from 0.1 keV and 10 MeV and then compared to the experim...
journal_title:Radiation protection dosimetry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.rpd.a006798
更新日期:2002-01-01 00:00:00