Quality of out-of-hospital cardiopulmonary resuscitation with real time automated feedback: a prospective interventional study.

Abstract:

AIMS:To compare quality of CPR during out-of-hospital cardiac arrest with and without automated feedback. MATERIALS AND METHODS:Consecutive adult, out-of-hospital cardiac arrests of all causes were studied. One hundred and seventy-six episodes (March 2002-October 2003) without feedback were compared to 108 episodes (October 2003-September 2004) where automatic feedback on CPR was given. Automated verbal and visual feedback was based on measured quality with a prototype defibrillator. Quality of CPR was the main outcome measure and survival was reported as specified in the protocol. RESULTS:Average compression depth increased from (mean +/- S.D.) 34 +/- 9 to 38 +/- 6 mm (mean difference (95% CI) 4 (2, 6), P < 0.001), and median percentage of compressions with adequate depth (38-51 mm) increased from 24% to 53% (P < 0.001, Mann-Whitney U-test) with feedback. Mean compression rate decreased from 121 +/- 18 to 109 +/- 12 min(-1) (difference -12 (-16, -9), P = 0.001). There were no changes in the mean number of ventilations per minute; 11 +/- 5 min(-1) versus 11 +/- 4 min(-1) (difference 0 (-1, 1), P = 0.8) or the fraction of time without chest compressions; 0.48 +/- 0.18 versus 0.45 +/- 0.17 (difference -0.03 (-0.08, 0.01), P = 0.08). With intention to treat analysis 7/241 control patients were discharged alive (2.9%) versus 5/117 with feedback (4.3%) (OR 1.5 (95% CI; 0.8, 3), P = 0.2). In a logistic regression analysis of all cases, witnessed arrest (OR 4.2 (95% CI; 1.6, 11), P = 0.004) and average compression depth (per mm increase) (OR 1.05 (95% CI; 1.01, 1.09), P = 0.02) were associated with rate of hospital admission. CONCLUSIONS:Automatic feedback improved CPR quality in this prospective non-randomised study of out-of-hospital cardiac arrest. Increased compression depth was associated with increased short-term survival. TRIAL REGISTRATION:ClinicalTrials.gov (NCT00138996), http://www.clinicaltrials.gov/.

journal_name

Resuscitation

journal_title

Resuscitation

authors

Kramer-Johansen J,Myklebust H,Wik L,Fellows B,Svensson L,Sørebø H,Steen PA

doi

10.1016/j.resuscitation.2006.05.011

subject

Has Abstract

pub_date

2006-12-01 00:00:00

pages

283-92

issue

3

eissn

0300-9572

issn

1873-1570

pii

S0300-9572(06)00269-3

journal_volume

71

pub_type

临床试验,杂志文章,多中心研究
  • Therapeutic hypothermia in neonates. Review of current clinical data, ILCOR recommendations and suggestions for implementation in neonatal intensive care units.

    abstract::Recent evidence suggests that the current ILCOR guidelines regarding hypothermia for the treatment of neonatal encephalopathy need urgent revision. In 2005 when the current ILCOR guidelines were finalised one large (CoolCap trial, n=235) and one small RCT (n=67), in addition to pilot trials, had been published, and de...

    journal_title:Resuscitation

    pub_type: 杂志文章,评审

    doi:10.1016/j.resuscitation.2008.04.027

    authors: Hoehn T,Hansmann G,Bührer C,Simbruner G,Gunn AJ,Yager J,Levene M,Hamrick SE,Shankaran S,Thoresen M

    更新日期:2008-07-01 00:00:00

  • Human ECGs corrupted with real CPR artefacts in an animal model: generating a database to evaluate and refine algorithms for eliminating CPR artefacts.

    abstract:AIM:For the analysis of ECG rhythms during ongoing CPR, single- or two-channel methods have been proposed to eliminate artefacts from the CPR-corrupted ECG. To refine, test and evaluate these algorithms with a realistic data set, we introduce an animal model with which we created an extended database of human ECGs with...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2010.03.003

    authors: Granegger M,Werther T,Roehrich M,Losert U,Gilly H

    更新日期:2010-06-01 00:00:00

  • Patterns of systemic oxygen utilization in cardiac ischemic syndromes: oxygen utilization in cardiac ischemia.

    abstract::Cardiac ischemia can present as distinctive clinical syndromes such as acute myocardial infarction, cardiogenic shock, sudden cardiac arrest or chronic congestive heart failure. All of the clinical syndromes share common pathophysiological events including reduction of cardiac output and systemic oxygen delivery (DO2)...

    journal_title:Resuscitation

    pub_type: 杂志文章,评审

    doi:10.1016/0300-9572(94)90065-5

    authors: Rady MY

    更新日期:1994-12-01 00:00:00

  • Cardioprotective effect of therapeutic hypothermia at 34°C against ischaemia/reperfusion injury mediated by PI3K and nitric oxide in a rat isolated heart model.

    abstract:AIM:Therapeutic hypothermia (TH) is widely used as a cardioprotective treatment for cardiac arrest. TH at 30-32°C during ischaemia and reperfusion has a cardioprotective effect. The aims of the study were to examine whether TH at 34°C with late induction (immediately after the start of reperfusion) has a cardioprotecti...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2011.08.013

    authors: Mochizuki T,Yu S,Katoh T,Aoki K,Sato S

    更新日期:2012-02-01 00:00:00

  • Comparison of relative and actual chest compression depths during cardiac arrest in children, adolescents, and young adults.

    abstract:AIM:Cardiopulmonary resuscitation (CPR) guidelines recommend specific chest compression (CC) target depths for children. We quantitatively describe relative anterior-posterior diameter (APD) depth, actual depth, and force of CCs during real CPR events in children. METHODS:CC depth and force were recorded during real C...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2011.10.014

    authors: Niles DE,Nishisaki A,Sutton RM,Nysæther J,Eilevstjønn J,Leffelman J,Maltese MR,Arbogast KB,Abella BS,Helfaer MA,Berg RA,Nadkarni VM

    更新日期:2012-03-01 00:00:00

  • Circulation detection using the electrocardiogram and the thoracic impedance acquired by defibrillation pads.

    abstract:AIM:To develop and evaluate a method to detect circulation in the presence of organized rhythms (ORs) during resuscitation using signals acquired by defibrillation pads. METHODS:Segments containing electrocardiogram (ECG) and thoracic impedance (TI) signals free of artifacts were used. The ECG corresponded to ORs clas...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2015.11.014

    authors: Alonso E,Aramendi E,Daya M,Irusta U,Chicote B,Russell JK,Tereshchenko LG

    更新日期:2016-02-01 00:00:00

  • Incidence and outcome from adult cardiac arrest occurring in the intensive care unit: a systematic review of the literature.

    abstract:BACKGROUND:Significant amount of data on the incidence and outcome of out-of-hospital and in-hospital cardiac arrest have been published. Cardiac arrest occurring in the intensive care unit has received less attention. AIMS:To evaluate and summarize current knowledge of intensive care unit cardiac arrest including qua...

    journal_title:Resuscitation

    pub_type: 杂志文章,评审

    doi:10.1016/j.resuscitation.2013.12.027

    authors: Efendijev I,Nurmi J,Castrén M,Skrifvars MB

    更新日期:2014-04-01 00:00:00

  • Advanced Cardiac Life Support Courses: live actors do not improve training results compared with conventional manikins.

    abstract:PRIMARY OBJECTIVE:To determine whether using live actors to increase the reality of the scenario improves knowledge retention in Advanced Cardiac Life Support (ACLS) Courses. MAIN SECONDARY OBJECTIVES: To determine the effects of age, time since graduation from nursing or medicine, sex, medical specialty, and workplace...

    journal_title:Resuscitation

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.resuscitation.2007.07.031

    authors: Miotto HC,Couto BR,Goulart EM,Amaral CF,Moreira Mda C

    更新日期:2008-02-01 00:00:00

  • Intracerebroventricular application of granulocyte colony-stimulating factor after cardiac arrest does not promote beneficial effects on cerebral recovery after cardiac arrest in rats.

    abstract:SUBJECT:Recent data demonstrated potent neuroprotective effects of growth hormones such as granulocyte colony-stimulating factor (G-CSF) after focal cerebral ischaemia. In order to assess possible effects of intracerebroventricular application of G-CSF on cerebral recovery after cardiac arrest (CA) in rats, neurologica...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2009.01.003

    authors: Popp E,Rabsahl T,Schneider A,Russ N,Spöhr F,Vogel P,Böttiger BW,Teschendorf P

    更新日期:2009-04-01 00:00:00

  • Analysis of amplitude spectral area and slope to predict defibrillation in out of hospital cardiac arrest due to ventricular fibrillation (VF) according to VF type: recurrent versus shock-resistant.

    abstract:BACKGROUND:In out-of-hospital cardiac arrest (OHCA) due to ventricular fibrillation (VF), VF may recur during resuscitation (recurrent VF) or fail to defibrillate (shock-resistant VF). While retrospective studies have suggested that amplitude spectral area (AMSA) and slope predict defibrillation, it is unknown whether ...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2012.02.008

    authors: Shanmugasundaram M,Valles A,Kellum MJ,Ewy GA,Indik JH

    更新日期:2012-10-01 00:00:00

  • A novel methodological framework for multimodality, trajectory model-based prognostication.

    abstract:INTRODUCTION:Prognostic tools typically combine several time-invariant clinical predictors using regression models that yield a single, time-invariant outcome prediction. This results in considerable information loss as repeatedly or continuously sampled data are aggregated into single summary measures. We describe a m...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2019.02.030

    authors: Elmer J,Jones BL,Zadorozhny VI,Puyana JC,Flickinger KL,Callaway CW,Nagin D

    更新日期:2019-04-01 00:00:00

  • Ketamine improves survival and suppresses IL-6 and TNFalpha production in a model of Gram-negative bacterial sepsis in rats.

    abstract:OBJECTIVE:In a previous study, ketamine suppressed Escherichia coli-induced production of the cytokines interleukin (IL)-6 and tumor necrosis factor alpha (TNF). In other previous studies ketamine improved survival after E. coli inoculation. However, the relationship between cytokines and survival following ketamine tr...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2004.02.015

    authors: Shaked G,Czeiger D,Dukhno O,Levy I,Artru AA,Shapira Y,Douvdevani A

    更新日期:2004-08-01 00:00:00

  • A randomized trial of compression first or analyze first strategies in patients with out-of-hospital cardiac arrest: results from an Asian community.

    abstract:BACKGROUND:It is still under debate whether a period of cardiopulmonary resuscitation should be performed prior to rhythm analysis for defibrillation for out of hospital cardiac arrests (OHCA). This study compared outcomes of OHCA treated by "compression first" (CF) versus "analyze first" (AF) strategies in an Asian co...

    journal_title:Resuscitation

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.resuscitation.2012.01.009

    authors: Ma MH,Chiang WC,Ko PC,Yang CW,Wang HC,Chen SY,Chang WT,Huang CH,Chou HC,Lai MS,Chien KL,Lee BC,Hwang CH,Wang YC,Hsiung GH,Hsiao YW,Chang AM,Chen WJ,Chen SC

    更新日期:2012-07-01 00:00:00

  • Improving cannulation time for extracorporeal life support in refractory cardiac arrest of presumed cardiac cause - Comparison of two percutaneous cannulation techniques in the catheterization laboratory in a center without on-site cardiovascular surgery.

    abstract:BACKGROUND:Cardiac arrest (CA) without return of spontaneous circulation can be treated with veno-arterial extracorporeal membrane oxygenation (vaECMO) implemented surgically or percutaneously. We performed a study assessing time for vaECMO percutaneous cannulation in the catheterization laboratory. METHODS:Single-cen...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2017.11.057

    authors: Voicu S,Henry P,Malissin I,Dillinger J-G,Koumoulidis A,Magkoutis N,Yannopoulos D,Logeart D,Manzo-Silberman S,Péron N,Deye N,Megarbane B,Sideris G

    更新日期:2018-01-01 00:00:00

  • Gender differences in early invasive strategy after cardiac arrest: Insights from the PROCAT registry.

    abstract:AIM:Early invasive strategy, including percutaneous coronary intervention (PCI), may improve survival in out-of-hospital-cardiac-arrest (OHCA) due to coronary artery disease but selection of suitable patients is challenging. Differences and results across gender remain unknown. We aimed to assess the relationship betwe...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2017.02.005

    authors: Bougouin W,Dumas F,Marijon E,Geri G,Champigneulle B,Chiche JD,Varenne O,Spaulding C,Mira JP,Jouven X,Cariou A

    更新日期:2017-05-01 00:00:00

  • Sudden cardiac arrest survival in HEARTSafe communities.

    abstract:BACKGROUND:The HEARTSafe Communities program promotes community efforts to improve systems for treating sudden cardiac arrest (SCA). The study hypothesis was that the rates of SCA survival to admission, discharge, and discharge with CPC score 1 or 2 are higher in HEARTSafe-designated communities than non-designated com...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2019.10.029

    authors: Cone DC,Burns K,Maciejewski K,Dziura J,McNally B,Vellano K,CARES Surveillance Group.

    更新日期:2020-01-01 00:00:00

  • Plasma lidocaine levels occurring with endotracheal administration during hemorrhagic shock.

    abstract::During the many emergency situations in which venous access is difficult or impossible, endotracheal drug administration is an effective alternative means of delivering life-saving medications. Shock is a commonly encountered emergency situation in which endotracheal drug therapy can and is often used. Yet whether a d...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/0300-9572(90)90108-q

    authors: Mace SE

    更新日期:1990-06-01 00:00:00

  • The cell in shock: the origin of multiple organ failure.

    abstract::The immediate organ damage seen after multiple trauma and in shock is a typical example of non-bacterial inflammation triggered by activation of various mediators of both the humoral and cellular systems. Anaphylatoxins and the low-flow syndrome during the shock phase account for increased PMN* margination, which in t...

    journal_title:Resuscitation

    pub_type: 杂志文章,评审

    doi:10.1016/0300-9572(91)90044-y

    authors: Schlag G,Redl H,Hallström S

    更新日期:1991-04-01 00:00:00

  • The use of endotracheal medication in cardiac emergencies.

    abstract::The endotracheal route for drug administration provides a rapid means of accessing the systemic circulation when intravenous routes cannot be established in emergent situations. This route is relatively free of significant complications and has been documented as being successful numerous times in various clinical set...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/0300-9572(84)90001-7

    authors: Greenberg MI

    更新日期:1984-11-01 00:00:00

  • Mean arterial pressure and vasopressor load after out-of-hospital cardiac arrest: Associations with one-year neurologic outcome.

    abstract:THE AIM OF THE STUDY:There are limited data on blood pressure targets and vasopressor use following cardiac arrest. We hypothesized that hypotension and high vasopressor load are associated with poor neurological outcome following out-of-hospital cardiac arrest (OHCA). METHODS:We included 412 patients with OHCA includ...

    journal_title:Resuscitation

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.resuscitation.2016.05.026

    authors: Laurikkala J,Wilkman E,Pettilä V,Kurola J,Reinikainen M,Hoppu S,Ala-Kokko T,Tallgren M,Tiainen M,Vaahersalo J,Varpula T,Skrifvars MB,FINNRESUSCI Study Group.

    更新日期:2016-08-01 00:00:00

  • Advanced cardiac life support training improves long-term survival from in-hospital cardiac arrest.

    abstract:CONTEXT:Advanced cardiac life support (ACLS) training was introduced to bring order and a systematic approach to the treatment of cardiac arrest by professional responders. In spite of the wide dissemination of ACLS training, it has been difficult to demonstrate improved outcome following such training. OBJECTIVE:To d...

    journal_title:Resuscitation

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.resuscitation.2006.06.039

    authors: Moretti MA,Cesar LA,Nusbacher A,Kern KB,Timerman S,Ramires JA

    更新日期:2007-03-01 00:00:00

  • Prehospital thrombolytic treatment of massive pulmonary embolism with reteplase during cardiopulmonary resuscitation.

    abstract::A 52-year-old previously healthy man experienced acute severe dyspnoea after suffering from gastroenteritis for 3 days. After arrival of the ambulance, cardiac arrest with an initial rhythm of electro mechanical dissociation occurred. Circulation was restored after 10 min of cardiopulmonary resuscitation but soon card...

    journal_title:Resuscitation

    pub_type: 杂志文章,评审

    doi:10.1016/s0300-9572(98)00066-5

    authors: Kuisma M,Silfvast T,Voipio V,Malmström R

    更新日期:1998-07-01 00:00:00

  • Dissemination of CPR video self-instruction materials to secondary trainees: Results from a hospital-based CPR education trial.

    abstract:BACKGROUND:Cardiopulmonary resuscitation (CPR) video self-instruction (VSI) materials have been promoted as a scalable approach to increase the prevalence of CPR skills among the lay public, in part due to the opportunity for secondary training (i.e., sharing of training materials). However, the motivations for, and ba...

    journal_title:Resuscitation

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.resuscitation.2015.12.016

    authors: Ikeda DJ,Buckler DG,Li J,Agarwal AK,Di Taranti LJ,Kurtz J,Reis RD,Leary M,Abella BS,Blewer AL

    更新日期:2016-03-01 00:00:00

  • Sports activity and paediatric out-of-hospital cardiac arrest at schools in Japan.

    abstract:BACKGROUND:Sudden cardiac death during exercise or sports is an important problem among young athletes and non-athletes. An understanding of the epidemiological features of sports-related out-of-hospital cardiac arrest (OHCA) among children is crucial for planning approaches for prevention and better outcomes of paedia...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2019.03.041

    authors: Sado J,Kiyohara K,Kitamura T,Matsui S,Ayusawa M,Nitta M,Iwami T,Nakata K,Sobue T,Kitamura Y,SPIRITS investigators.

    更新日期:2019-06-01 00:00:00

  • Comparison of sodium bicarbonate with dichloroacetate treatment of hyperlactatemia and lactic acidosis in the ischemic rat.

    abstract::Serum lactic acidosis is characterized by a pH less than 7.25 and lactate greater than 5 mEq. Although sodium bicarbonate (NaHCO3) is standard treatment for this condition, clinical and experimental studies suggest that high doses of NaHCO3 may be ineffectual or even detrimental to brain, cardiovascular, and respirato...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/0300-9572(88)90015-9

    authors: Dimlich RV,Biros MH,Widman DW,Kaplan J

    更新日期:1988-01-01 00:00:00

  • A pragmatic checklist to identify pediatric ICU patients at risk for cardiac arrest or code bell activation.

    abstract:BACKGROUND:In-hospital cardiac arrest is a rare event associated with significant morbidity and mortality. The ability to identify the ICU patients at risk for cardiac arrest could allow the clinical team to prepare staff and equipment in anticipation. METHODS:This pilot study was completed at a large tertiary care pe...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2015.11.017

    authors: Niles DE,Dewan M,Zebuhr C,Wolfe H,Bonafide CP,Sutton RM,DiLiberto MA,Boyle L,Napolitano N,Morgan RW,Stinson H,Leffelman J,Nishisaki A,Berg RA,Nadkarni VM

    更新日期:2016-02-01 00:00:00

  • Decision making to cease or to continue cardiopulmonary resuscitation (CPR). The Cerebral Resuscitation Study Group.

    abstract::CPR should be initiated in any patient who has a cardiac arrest. This might improve overall outcome but implies that CPR is started in patients without any virtual chance for long-term survival (LTS). The aim of this study is, by analysing retrospectively 2713 out-of-hospital cardiac arrests (CA), to identify indices ...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/0300-9572(89)90098-1

    authors: Van Hoeyweghen R,Mullie A,Bossaert L

    更新日期:1989-01-01 00:00:00

  • The contribution of comorbidity and medication use to poor outcome from out-of-hospital cardiac arrest at home locations.

    abstract:INTRODUCTION:Out-of-hospital cardiac arrest (OHCA) at home is associated with lower rates of shockable initial rhythm and survival than OHCA in a public location. We determined whether medical history and medication use explain the association between OHCA location and presence of shockable initial rhythm and survival ...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2020.03.011

    authors: Hulleman M,Oving I,Homma PCM,Beesems SG,Tan HL,Koster RW,Blom MT

    更新日期:2020-06-01 00:00:00

  • Hemodynamic effects of active compression-decompression after prolonged CPR.

    abstract:BACKGROUND:This study was designed to test the effects of active compression-decompression (ACD) versus standard (STD) cardiopulmonary resuscitation (CPR) on hemodynamics after prolonged cardiac arrest (CA). METHODS AND RESULTS:After nontraumatic prehospital CA, 21 patients were resuscitated in a prospective nonblinde...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/0300-9572(95)00934-5

    authors: Malzer R,Zeiner A,Binder M,Domanovits H,Knappitsch G,Sterz F,Laggner AN

    更新日期:1996-06-01 00:00:00

  • Is there a role for remote ischaemic postconditioning in cardiopulmonary resuscitation?

    abstract::Cardiac arrest causes whole body ischaemic injury and cellular death. Successful cardiopulmonary resuscitation (CPR) can subsequently lead to a global reperfusion phenomenon with a paradoxically increased rate of cellular death. Interventions that decrease the ischaemia-reperfusion injury may be useful in the treatmen...

    journal_title:Resuscitation

    pub_type: 杂志文章,评审

    doi:10.1016/j.resuscitation.2010.06.016

    authors: Mouton R,Abella BS,Soar J

    更新日期:2010-11-01 00:00:00