Advanced cardiac life support training improves long-term survival from in-hospital cardiac arrest.

Abstract:

CONTEXT:Advanced cardiac life support (ACLS) training was introduced to bring order and a systematic approach to the treatment of cardiac arrest by professional responders. In spite of the wide dissemination of ACLS training, it has been difficult to demonstrate improved outcome following such training. OBJECTIVE:To determine the value of formal ACLS training in improving survival from in-hospital cardiac arrest. DESIGN, SETTING, AND PARTICIPANTS:A multi-center, prospective cohort study examined patient outcomes after resuscitation efforts by in-hospital rescue teams with and without ACLS-trained personnel. A total of 156 patients, experiencing 172 in-hospital cardiopulmonary arrest events over a 38-month period (January 1998 to March 2001) were studied. MAIN OUTCOME MEASURES:Primary endpoints included return of spontaneous circulation (ROSC), survival to hospital discharge, 30-day survival, and 1-year survival. RESULTS:The immediate success of resuscitation efforts for all patients was 39.7% (62/156). There was a significant increase in ROSC with ACLS-trained personnel (49/113; 43.4%) versus no ALCS-trained personnel (16/59; 27.1%; p=0.04). Likewise, patients treated by ACLS-trained personnel had increased survival to hospital discharge (26/82; 31.7% versus 7/34; 20.6%; p=0.23), significantly better 30-day survival (22/82; 26.8% versus 2/34; 5.9%; p<0.02), and significantly improved 1-year survival (18/82; 21.9% versus 0/34; 0%; p<0.002). CONCLUSION:The presence of at least one ACLS-trained team member at in-hospital resuscitation efforts increases both short and long-term survival following cardiac arrest.

journal_name

Resuscitation

journal_title

Resuscitation

authors

Moretti MA,Cesar LA,Nusbacher A,Kern KB,Timerman S,Ramires JA

doi

10.1016/j.resuscitation.2006.06.039

subject

Has Abstract

pub_date

2007-03-01 00:00:00

pages

458-65

issue

3

eissn

0300-9572

issn

1873-1570

pii

S0300-9572(06)00386-8

journal_volume

72

pub_type

杂志文章,多中心研究
  • Cardiac complications in preterm infants with percutaneous long lines: the importance of early diagnosis.

    abstract::Percutaneous long lines, routinely used in preterm infants, can be associated with several cardiac complications such as pericardial effusion and consequent cardiac tamponade. We report three patients with pericardial effusion highlighting the importance of cardiac ultrasound monitoring to both early diagnosis and tre...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2008.07.023

    authors: Fusco FP,De Carolis MP,Costa S,De Rosa G,Zambraro A,Romagnoli C

    更新日期:2008-12-01 00:00:00

  • The impact of double sequential external defibrillation on termination of refractory ventricular fibrillation during out-of-hospital cardiac arrest.

    abstract:BACKGROUND:Despite significant advances in resuscitation efforts, there are some patients who remain in ventricular fibrillation (VF) after multiple shocks during out-of-hospital cardiac arrest (OHCA). Double sequential external defibrillation (DSED) has been proposed as a treatment option for patients in refractory VF...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2019.04.038

    authors: Cheskes S,Wudwud A,Turner L,McLeod S,Summers J,Morrison LJ,Verbeek PR

    更新日期:2019-06-01 00:00:00

  • Investigation of the possibility of using ischemia-modified albumin as a novel and early prognostic marker in cardiac arrest patients after cardiopulmonary resuscitation.

    abstract:BACKGROUND:Early and accurate prediction of survival to hospital discharge following resuscitation after cardiac arrest (CA) is a major challenge. Our aim was to investigate the levels of ischemia-modified albumin (IMA) and malondialdehyde (MDA) in CA patients and whether IMA levels are valuable early marker of post-ca...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2009.06.007

    authors: Turedi S,Gunduz A,Mentese A,Dasdibi B,Karahan SC,Sahin A,Tuten G,Kopuz M,Alver A

    更新日期:2009-09-01 00:00:00

  • Chest wall injuries following cardiopulmonary resuscitation.

    abstract::The forensic records were reviewed of 1823 deaths referred to Edinburgh City Mortuary for autopsy over a 15-month period, 2000-2001; 499 cases (343 males, 156 females) that received CPR prior to death were studied. Rib fractures were found in 29%, sternal fracture in 14%, and 11% of cases showed external chest wall br...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2004.07.005

    authors: Black CJ,Busuttil A,Robertson C

    更新日期:2004-12-01 00:00:00

  • Delays and errors in cardiopulmonary resuscitation and defibrillation by pediatric residents during simulated cardiopulmonary arrests.

    abstract:BACKGROUND:The quality of life support delivered during cardiopulmonary resuscitation affects outcomes. However, little data exist regarding the quality of resuscitation delivered to children and factors associated with adherence to American Heart Association (AHA) resuscitation guidelines. PARTICIPANTS:Pediatric resi...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2009.03.020

    authors: Hunt EA,Vera K,Diener-West M,Haggerty JA,Nelson KL,Shaffner DH,Pronovost PJ

    更新日期:2009-07-01 00:00:00

  • Patterns of systemic oxygen utilization in cardiac ischemic syndromes: oxygen utilization in cardiac ischemia.

    abstract::Cardiac ischemia can present as distinctive clinical syndromes such as acute myocardial infarction, cardiogenic shock, sudden cardiac arrest or chronic congestive heart failure. All of the clinical syndromes share common pathophysiological events including reduction of cardiac output and systemic oxygen delivery (DO2)...

    journal_title:Resuscitation

    pub_type: 杂志文章,评审

    doi:10.1016/0300-9572(94)90065-5

    authors: Rady MY

    更新日期:1994-12-01 00:00:00

  • Testing the effects of checklists on team behaviour during emergencies on general wards: An observational study using high-fidelity simulation.

    abstract:INTRODUCTION:Clinical teams struggle on general wards with acute management of deteriorating patients. We hypothesized that the Crisis Checklist App, a mobile application containing checklists tailored to crisis-management, can improve teamwork and acute care management. METHODS:A before-and-after study was undertaken...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2020.09.031

    authors: De Bie Dekker AJR,Dijkmans JJ,Todorovac N,Hibbs R,Boe Krarup K,Bouwman AR,Barach P,Fløjstrup M,Cooksley T,Kellett J,Bindels AJGH,Korsten HHM,Brabrand M,Subbe CP

    更新日期:2020-12-01 00:00:00

  • Resuscitation of out-of-hospital cardiac arrest by Asian primary health-care physicians.

    abstract:AIM:To assess the experience, knowledge and attitudes of local primary health-care doctors towards resuscitation in out-of-hospital cardiac arrest. METHODS:We conducted a survey of general practitioners (GPs) working in both private and public sectors. The survey consisted of 29 questions and was self-administered. R...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2004.11.021

    authors: Ong ME,Chan YH,Ang HY,Lim SH,Tan KL

    更新日期:2005-05-01 00:00:00

  • Impact of first documented rhythm on cost-effectiveness of extracorporeal cardiopulmonary resuscitation.

    abstract:OBJECTIVES:Recommendations for extracorporeal cardiopulmonary resuscitation (ECPR) state that appropriate patient selection is important for the sake of efficacy and cost-effectiveness of ECPR. It is not known whether first documented rhythm plays a prominent role in economic outcomes of patients with cardiac arrest wh...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2019.05.013

    authors: Kawashima T,Uehara H,Miyagi N,Shimajiri M,Nakamura K,Chinen T,Hatano S,Nago C,Chiba S,Nakane H,Gima Y

    更新日期:2019-07-01 00:00:00

  • Ivabradine but not propranolol delays the time to onset of ischaemia-induced ventricular fibrillation by preserving myocardial metabolic energy status.

    abstract:OBJECTIVE:Heart rate reduction (HRR) has shown a beneficial impact on the prevention of ventricular fibrillation, which could be explained by increased myocardial blood flow and preservation of mitochondrial structure. Here, we assessed the HRR impact on time to onset of ventricular fibrillation (TOVF) and myocardial m...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2012.07.041

    authors: Vaillant F,Dehina L,Dizerens N,Bui-Xuan B,Tabib A,Lauzier B,Chevalier P,Descotes J,Timour Q

    更新日期:2013-03-01 00:00:00

  • Impact of the direct transfer to percutaneous coronary intervention-capable hospitals on survival to hospital discharge for patients with out-of-hospital cardiac arrest.

    abstract:AIMS:Patients suffering from out-of-hospital cardiac arrest (OHCA) are frequently transported to the closest hospital. Percutaneous coronary intervention (PCI) is often indicated following OHCA. This study's primary objective was to determine the association between being transported to a PCI-capable hospital and survi...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2018.01.048

    authors: Cournoyer A,Notebaert É,de Montigny L,Ross D,Cossette S,Londei-Leduc L,Iseppon M,Lamarche Y,Sokoloff C,Potter BJ,Vadeboncoeur A,Larose D,Morris J,Daoust R,Chauny JM,Piette É,Paquet J,Cavayas YA,de Champlain F,Segal

    更新日期:2018-04-01 00:00:00

  • Long-Term Survival Trends of Medicare Patients After In-Hospital Cardiac Arrest: Insights from Get With The Guidelines-Resuscitation®.

    abstract:BACKGROUND:Although rates of survival to hospital discharge after in-hospital cardiac arrest (IHCA) have improved over the last decade, it is unknown if these survival gains are sustained after hospital discharge. OBJECTIVE:To examine 1-year survival trends overall and by rhythm after IHCA. METHODS:Using Medicare ben...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2017.10.023

    authors: Thompson LE,Chan PS,Tang F,Nallamothu BK,Girotra S,Perman SM,Bose S,Daugherty SL,Bradley SM,American Heart Association’s Get With the Guidelines-Resuscitation Investigators.

    更新日期:2018-02-01 00:00:00

  • Comparison of two intraosseous infusion systems for adult emergency medical use.

    abstract:INTRODUCTION:The current guidelines of the European Resuscitation Council (ERC) stipulate that an intraosseous access should be placed if establishing a peripheral venous access for cardiopulmonary resuscitation (CPR) would involve delays. The aim of this study was therefore to compare a manual intraosseous infusion te...

    journal_title:Resuscitation

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.resuscitation.2008.04.004

    authors: Brenner T,Bernhard M,Helm M,Doll S,Völkl A,Ganion N,Friedmann C,Sikinger M,Knapp J,Martin E,Gries A

    更新日期:2008-09-01 00:00:00

  • Myocardial perfusion pressure: a predictor of 24-hour survival during prolonged cardiac arrest in dogs.

    abstract::Myocardial perfusion pressure, defined as the aortic diastolic pressure minus the right atrial diastolic pressure, correlates with coronary blood flow during cardiopulmonary resuscitation (CPR) and predicts initial resuscitation success. Whether this hemodynamic parameter can predict 24-h survival is not known. We exa...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/0300-9572(88)90111-6

    authors: Kern KB,Ewy GA,Voorhees WD,Babbs CF,Tacker WA

    更新日期:1988-10-01 00:00:00

  • International EMS systems: France.

    abstract::The EMS (Emergency Medical Service) system in France is a centrally based, two-tiered, physician-manned system. The first level is composed of BLS (Basic Life Support) fire department ambulances (called "VSAB") based at fire stations. The second level is composed of ALS (Advanced Life Support) physician staffed-ambula...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2004.04.001

    authors: Adnet F,Lapostolle F

    更新日期:2004-10-01 00:00:00

  • Dissemination of CPR video self-instruction materials to secondary trainees: Results from a hospital-based CPR education trial.

    abstract:BACKGROUND:Cardiopulmonary resuscitation (CPR) video self-instruction (VSI) materials have been promoted as a scalable approach to increase the prevalence of CPR skills among the lay public, in part due to the opportunity for secondary training (i.e., sharing of training materials). However, the motivations for, and ba...

    journal_title:Resuscitation

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.resuscitation.2015.12.016

    authors: Ikeda DJ,Buckler DG,Li J,Agarwal AK,Di Taranti LJ,Kurtz J,Reis RD,Leary M,Abella BS,Blewer AL

    更新日期:2016-03-01 00:00:00

  • Quantitative pupillometry and transcranial Doppler measurements in patients treated with hypothermia after cardiac arrest.

    abstract:BACKGROUND:Predicting outcome after cardiac arrest (CA) is particularly difficult when therapeutic hypothermia (TH) is used. We investigated the performance of quantitative pupillometry and transcranial Doppler (TCD) in this context. METHODS:This prospective observational study included 82 post-CA patients. Quantitati...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2016.02.026

    authors: Heimburger D,Durand M,Gaide-Chevronnay L,Dessertaine G,Moury PH,Bouzat P,Albaladejo P,Payen JF

    更新日期:2016-06-01 00:00:00

  • Brain tissue oxygen pressure and cerebral metabolism in an animal model of cardiac arrest and cardiopulmonary resuscitation.

    abstract:OBJECTIVE:Direct measurement of brain tissue oxygenation (PbtO2) is established during spontaneous circulation, but values of PbtO2 during and after cardiopulmonary resuscitation (CPR) are unknown. The purpose of this study was to investigate: (1) the time-course of PbtO2 in an established model of CPR, and (2) the cha...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2006.03.007

    authors: Cavus E,Bein B,Dörges V,Stadlbauer KH,Wenzel V,Steinfath M,Hanss R,Scholz J

    更新日期:2006-10-01 00:00:00

  • Cardiopulmonary resuscitation for hospital inpatients in Taiwan: an 8-year nationwide survey.

    abstract:AIM:Cardiopulmonary resuscitation (CPR) is widely used to treat cardiac arrest, but the success rate has remained unchanged for decades. This study evaluated CPR performance and success rate among hospital inpatients in Taiwan. METHODS:National Health Insurance data from 1997 to 2004 of population-based datasets repre...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2011.09.006

    authors: Lin MH,Peng LN,Chen LK,Chen TJ,Hwang SJ

    更新日期:2012-03-01 00:00:00

  • A geospatial analysis of persons opting out of an exception from informed consent out-of-hospital clinical trial.

    abstract:STUDY OBJECTIVE:For trials involving exception from informed consent, some IRBs require that community members be allowed to "opt out" prior to enrollment. We tested for geospatial clustering of opt-out requests and the associated census tract characteristics in one study region. METHODS:This was a retrospective study...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2008.10.003

    authors: Nelson MJ,Warden C,Griffiths D,Zive D,Schmidt T,Hedges JR,Daya M,Newgard CD

    更新日期:2009-01-01 00:00:00

  • Family presence during resuscitation and invasive procedures: physicians' and nurses' attitudes working in pediatric departments in Greece.

    abstract:BACKGROUND:Family presence during resuscitation and invasive procedures (FPDRAIP) has been a frequent topic of debate among healthcare personnel worldwide. This paper determines the knowledge, experiences and views of Greek physicians and nurses on FPDRAIP and examines possible correlations and factors promoting or lim...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2011.02.011

    authors: Vavarouta A,Xanthos T,Papadimitriou L,Kouskouni E,Iacovidou N

    更新日期:2011-06-01 00:00:00

  • Intra-aortic balloon counterpulsation in the emergency department: a 7-year review and analysis of predictors of survival.

    abstract:BACKGROUND:Intra-aortic balloon pump (IABP) counterpulsation in cardiogenic shock (CS) is suggested as bridging therapy to definite emergency revascularization, heart transplantation and acute valvular repair. Data concerning the use of IABP counterpulsation in an emergency department (ED) are rare. PATIENTS AND METHO...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/s0300-9572(02)00036-9

    authors: Bur A,Bayegan K,Holzer M,Herkner H,Schreiber W,Siostrzonek P,Hirschl MM,Laggner AN,Domanovits H

    更新日期:2002-06-01 00:00:00

  • Measuring survival rates from sudden cardiac arrest: the elusive definition.

    abstract:BACKGROUND:Measuring survival from sudden out-of-hospital cardiac arrest (OOH-CA) is often used as a benchmark of the quality of a community's emergency medical service (EMS) system. The definition of OOH-CA survival rates depends both upon the numerator (surviving cases) and the denominator (all cases). PURPOSE:The p...

    journal_title:Resuscitation

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.resuscitation.2004.02.007

    authors: Sayre MR,Travers AH,Daya M,Greene HL,Salive ME,Vijayaraghavan K,Craven RA,Groh WJ,Hallstrom AP,PAD Investigators.

    更新日期:2004-07-01 00:00:00

  • S(p)O(2) values in acute medical admissions breathing air--implications for the British Thoracic Society guideline for emergency oxygen use in adult patients?

    abstract::S(p)O(2) is routinely used to assess the well-being of patients, but it is difficult to find an evidence-based description of its normal range. The British Thoracic Society (BTS) has published guidance for oxygen administration and recommends a target S(p)O(2) of 94-98% for most adult patients. These recommendations r...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2012.06.002

    authors: Smith GB,Prytherch DR,Watson D,Forde V,Windsor A,Schmidt PE,Featherstone PI,Higgins B,Meredith P

    更新日期:2012-10-01 00:00:00

  • Cerebral blood flow velocity and autoregulation in paediatric patients following a global hypoxic-ischaemic insult.

    abstract:AIM:To describe the cerebral blood flow velocity pattern and investigate cerebral autoregulation using transcranial Doppler ultrasonography (TCD) following a global hypoxic-ischaemic (HI) event in children. METHODS:This was a prospective, observational study in a quaternary-level paediatric intensive care unit. Intuba...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2018.02.005

    authors: Lovett ME,Maa T,Chung MG,O'Brien NF

    更新日期:2018-05-01 00:00:00

  • Continuous cardiac index monitoring: A prospective observational study of agreement between a pulmonary artery catheter and a calibrated minimally invasive technique.

    abstract:INTRODUCTION:Continuous cardiac index (CCI) monitoring can provide information to assist in hemodynamic support. However, pulmonary artery catheters (PAC) pose logistic challenges in acute care settings. We hypothesized that CCI measured with a calibrated minimally invasive technique (LiDCO/PulseCO, UK) would have good...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2009.04.015

    authors: McCoy JV,Hollenberg SM,Dellinger RP,Arnold RC,Ruoss L,Lotano V,Peters P,Parrillo JE,Trzeciak S

    更新日期:2009-08-01 00:00:00

  • A modeling approach to the effects of force guided versus depth guided compression during cardiopulmonary resuscitation on different chests and back support surfaces.

    abstract:OBJECTIVES:To validate an existing theoretical model for the mechanics of chest compression (CC) during constant peak force cardiopulmonary resuscitation (CPR) using experimental human and manikin CC data from the literature. Also, to gain insights into the clinical application of force guided CPR. METHODS:The experim...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2012.11.027

    authors: Dellimore KH,Scheffer C

    更新日期:2013-06-01 00:00:00

  • A feasibility study for the continuous measurement of pupillary response using the pupillography during CPR in out-of-hospital cardiac arrest patients.

    abstract:PURPOSE:We investigated the change in pupil size and pupil light reflex (PLR) using a pupillography capable of continuous measurement both during CPR and immediately following the return-of-spontaneous circulation (ROSC) in out-of-hospital cardiac arrest (OHCA) comatose patients in an emergency department. METHODS:Pup...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2018.11.016

    authors: Lee HJ,Shin J,Hong KJ,Jung JH,Lee SJ,Jung E,You KM,Kim TH

    更新日期:2019-02-01 00:00:00

  • Cardiac arrest in Irish general practice: an observational study from 426 general practices.

    abstract:SETTING:Sudden Cardiac Death accounts for approximately 5000 deaths in Ireland each year. Nationally, out-of-hospital cardiac arrest has a very low resuscitation rate, reported at less than 5%. Ireland has a well developed general practice network which routinely manages emergencies arising in the community setting. Ho...

    journal_title:Resuscitation

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.resuscitation.2009.07.010

    authors: Bury G,Headon M,Dixon M,Egan M

    更新日期:2009-11-01 00:00:00

  • The incidence and significance of bacteremia in out of hospital cardiac arrest.

    abstract:BACKGROUND:The most common etiology of cardiac arrest is presumed of myocardial origin. Recent retrospective studies indicate that preexisting pneumonia, a form of sepsis, is frequent in patients who decompensate with abrupt cardiac arrest without preceding signs of septic shock, respiratory failure or severe metabolic...

    journal_title:Resuscitation

    pub_type: 杂志文章

    doi:10.1016/j.resuscitation.2013.09.022

    authors: Coba V,Jaehne AK,Suarez A,Dagher GA,Brown SC,Yang JJ,Manteuffel J,Rivers EP

    更新日期:2014-02-01 00:00:00