Biodosimetry using chromosome aberrations in human lymphocytes.

Abstract:

:In vitro dose-response calibration curves for (60)Co gamma rays have been established for unstable chromosome aberrations in human peripheral blood lymphocytes. The observed dose-response data were fitted to a linear quadratic model. The calibration curve parameters were used to estimate the equivalent whole-body dose and dose to the irradiated region in partial body irradiation of cancer patients. The derived partial body doses and fractions of lymphocytes irradiated were in agreement with those estimated from the radiotherapy regimes.

journal_name

Radiat Prot Dosimetry

authors

Senthamizhchelvan S,Pant GS,Rath GK,Julka PK,Nair O,Joshi RC,Malhotra A,Pandey RM

doi

10.1093/rpd/ncl109

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

241-5

issue

2

eissn

0144-8420

issn

1742-3406

pii

ncl109

journal_volume

123

pub_type

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