Effect of prophylactic bisoprolol plus magnesium on the incidence of atrial fibrillation after coronary bypass surgery: results of a randomized controlled trial.

abstract：:The manifestation of pain in any individual patient may result from a variety of underlying mechanisms that also may vary from one disease state to another. Global measures of pain intensity and relief are inadequate for characterizing specific pain qualities or identifying the unique effects of pain treatments on dif...

journal_title：Current medical research and opinion

authors： Jensen MP

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:Compare costs and healthcare resource utilization (HCRU) among newly-diagnosed non-valvular atrial fibrillation (NVAF) patients newly treated with dabigatran vs apixaban, rivaroxaban, or warfarin. METHODS:Newly-diagnosed adult NVAF patients initiating dabigatran, apixaban, rivaroxaban, or warfarin (index ev...

journal_title：Current medical research and opinion

authors： Gilligan AM,Franchino-Elder J,Song X,Wang C,Henriques C,Sainski-Nguyen A,Wilson K,Smith DM,Sander S

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:The Exenatide BID Observational Study (ExOS) was designed to evaluate the clinical effectiveness of exenatide BID use in patients with type 2 diabetes (T2D) in a real-world clinical practice setting in the United States. METHODS:Patients were enrolled from 74 practice sites from 9/2007 through 1/2009 and fol...

journal_title：Current medical research and opinion

authors： Bergenstal RM,Garrison LP Jr,Miller LA,Hou L,Blickensderfer A,Zagar A,Stanley S,Bhargava A,Wade R,Herman WH

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:In patch-based transdermal drug delivery, adhesiveness is critical for safe and effective treatment, especially in Parkinson's disease (PD) where excessive sweating is common. This study compared the adhesiveness of two transdermal patch formulations of rotigotine (improved room temperature-stable [PR2.3.1/Tr...

journal_title：Current medical research and opinion

authors： Elshoff JP,Bauer L,Goldammer N,Oortgiesen M,Pesch H,Timmermann L

更新日期：2018-07-01 00:00:00

abstract：:In this narrative review, we will discuss some of the significant risks and dramatic consequences that are associated with epilepsy: depression, suicide, seizure-related injuries, and mortality, both in adults and in children. Considering the high prevalence of depression among people with epilepsy (PWE), routine and ...

journal_title：Current medical research and opinion

authors： Mesraoua B,Deleu D,Hassan AH,Gayane M,Lubna A,Ali MA,Tomson T,Khalil BA,Cross JH,Asadi-Pooya AA

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Studies have shown that many patients with type 2 diabetes do not achieve optimal glycemic control, and progression of diabetes over time requires more than one pharmacotherapy to achieve glycemic goal. OBJECTIVE:To examine the efficacy and safety of the fixed-dose combination (FDC) of pioglitazone 15 mg an...

journal_title：Current medical research and opinion

authors： Perez A,Zhao Z,Jacks R,Spanheimer R

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:Osteoporosis is a skeletal disorder characterized by diminished bone strength, which results in an increased risk of fracture. Currently, osteoporosis is a public health priority due to the large number of individuals affected and the detrimental effect on quality of life. Primary osteoporosis, the most commo...

journal_title：Current medical research and opinion

authors： Brandi ML,Minisola S

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Omega-3 fatty acids from fish and fish oils can protect against coronary heart disease (CHD), which is still the most common cause of death in the Western economies. Evidence from epidemiological and case cohort studies indicate that consumpton of fatty fish and omega-3 fatty acids reduces the risk of cardio...

journal_title：Current medical research and opinion

authors： Harrison N,Abhyankar B

更新日期：2005-01-01 00:00:00

abstract：:Two hundred and two patients with symptoms, signs and mycological evidence of Candida vaginitis were entered in a single-blind trial comparing 6-day clotrimazole therapy with a control group receiving 6 days' nystatin therapy. Adequate data was collected on 69 clotrimazole and 72 nystatin treated patients for analysis...

journal_title：Current medical research and opinion

authors： Masterton G,Henderson J,Napier IR,Moffet M

更新日期：1975-01-01 00:00:00

abstract：OBJECTIVE:This study was designed to assess the safety of 25- and 50-mg dosage strengths of zonisamide for initial titration in patients with epilepsy. RESEARCH DESIGN AND METHODS:This phase 3, multicenter, open-label, uncontrolled study conducted at 26 study sites in the United States included male and female patient...

journal_title：Current medical research and opinion

authors： Uthman BM,Miller GS,Montouris G,James SP,Anthony S,Zonisamide 501 Study Group.

更新日期：2004-06-01 00:00:00

abstract：:Twenty-seven patients with tennis elbow were treated with triamcinolone acetonide (40 mg/ml) injected locally into the tender area without local anaesthetic. Reduction of pain or complete relief was achieved in 1 to 72 hours, although in 9 cases exacerbation of pain occurred before relief was given. The recurrence rat...

journal_title：Current medical research and opinion

authors： Nevelös AB

更新日期：1980-01-01 00:00:00

abstract：:Although the statistical strength of direct comparative randomized controlled trials is generally acknowledged, the particular demands of therapeutic decision making will often require indirect comparisons to be made, based on pooled data from multiple trials. As for all post-hoc analyses, the process of indirect comp...

journal_title：Current medical research and opinion

authors： Belsey JD

更新日期：2015-02-01 00:00:00

abstract：:Cardiac arrhythmias are the most common cardiac complication reported in pregnant women with and without structural heart disease (SHD); they are more frequent among women with SHD, such as cardiomyopathy and congenital heart disease (CHD). While older studies had indicated supraventricular tachycardia as the most com...

journal_title：Current medical research and opinion

authors： Manolis TA,Manolis AA,Apostolopoulos EJ,Papatheou D,Melita H,Manolis AS

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The rising prevalence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) and the recent emergence of community-associated MRSA are major clinical, public health, and economic challenges. MRSA is a leading cause of nosocomial pneumonia and complicated skin and soft-tissue infections (cSSTI). Van...

journal_title：Current medical research and opinion

authors： Stein GE,Wells EM

更新日期：2010-03-01 00:00:00

abstract：UNLABELLED:Abstract Background: The Schizophrenia Trial of Aripiprazole (STAR) showed superior efficacy for aripiprazole compared with atypical antipsychotic standard-of-care (SOC) for the community treatment of schizophrenia 1 based on the Investigator Assessment Questionnaire total score. OBJECTIVE:To determine the ...

journal_title：Current medical research and opinion

authors： King D,Knapp M,Thomas P,Razzouk D,Loze JY,Kan HJ,van Baardewijk M

更新日期：2011-02-01 00:00:00

abstract：:A clinical trial was undertaken in 50 patients with osteoarthritis of the knee to assess the therapeutic value of glycosaminoglycan-peptide complex in treatment. The first year consisted of a randomized, double-blind, placebo-controlled, parallel-group trial (25 patients in each group), after which all patients receiv...

journal_title：Current medical research and opinion

authors： Katona G

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVES:Docetaxel and paclitaxel show significant clinical activity in metastatic breast cancer (MBC) and have been approved for MBC by the U.S. Food and Drug Administration, but it is still unclear whether a paclitaxel-based regimen improves outcomes over a docetaxel-based regimen in patients with MBC. We therefore...

journal_title：Current medical research and opinion

authors： Qi WX,Shen Z,Lin F,Sun YJ,Min DL,Tang LN,He AN,Yao Y

更新日期：2013-02-01 00:00:00

abstract：:A study was carried out to compare the efficacy and tolerability of etodolac and piroxicam in patients with rheumatoid arthritis. Sixty patients entered this double-blind, parallel study and after a wash-out period of up to 2 weeks were randomly assigned to receive 200 mg etodolac twice daily or 20 mg piroxicam once d...

journal_title：Current medical research and opinion

authors： Schattenkirchner M

更新日期：1991-01-01 00:00:00

abstract：:An open study was carried out in 40 elderly patients suffering from osteoarthrosis of the hip to assess the effectiveness of 200 mg flurbiprofen daily, fiven either in tablet or liquid suspension form, over a period of 4 weeks. Statistical evaluation of the results in the 19 patients admitted to analysis showed that f...

journal_title：Current medical research and opinion

authors： Innes EH

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:To examine the economic burden of myelodysplastic syndromes (MDS) and the incremental cost of transfusion dependence. RESEARCH DESIGN AND METHODS:Adults with evidence of MDS were identified between 05/01/2000 and 09/30/2003 from a longitudinal, retrospective claims database for a large, geographically divers...

journal_title：Current medical research and opinion

authors： Frytak JR,Henk HJ,De Castro CM,Halpern R,Nelson M

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Lowering intraocular pressure (IOP) is currently the only therapeutic approach that preserves visual function in primary open-angle glaucoma. In making treatment decisions for first- and second-line therapy, the clinician needs to provide an appropriate balance of efficacy and tolerability. Prostaglandin ana...

journal_title：Current medical research and opinion

authors： Aptel F,Denis P

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:This survey assessed the impact of symptoms of COPD on patients' ability to perform activities throughout the day and the extent to which physicians provided advice including how medications may help maintain quality of life. METHODS:The survey had three inclusion criteria--physician's diagnosis of COPD, ag...

journal_title：Current medical research and opinion

authors： O'Hagan P,Chavannes NH

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the influence of age, sex, and previous opioid experience on the likelihood of successfully titrating opioid-naive and experienced patients with chronic low back pain (CLBP) to an effective and well-tolerated dose of oxymorphone extended release (ER). METHODS:Post hoc analysis of open-label titra...

journal_title：Current medical research and opinion

authors： Peniston JH,Xiang Q,Gould EM

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical efficacy and safety of mometasone furoate administered via a dry powder inhaler (MF-DPI) in Japanese patients with intermittent or mild persistent asthma who were not previously receiving inhaled corticosteroids. RESEARCH DESIGN AND METHODS:This was an 8-week open-label study conduct...

journal_title：Current medical research and opinion

authors： Tohda Y,Miyamoto T

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether gum chewing affects perceived levels of everyday stress among persons who (1) regularly chew gum or (2) do not chew gum on a regular basis. RESEARCH DESIGN AND METHODS:Two Internet-based studies were conducted. Study 1 enrolled participants who chewed gum > or =4 days per week, chewed ...

journal_title：Current medical research and opinion

authors： Zibell S,Madansky E

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of epoetin theta and epoetin beta in anaemic patients with chronic kidney disease, undergoing haemodialysis and previously on stable maintenance therapy with epoetin beta. METHODS:In this multicentre, randomised, controlled, double-blind study 270 haemodialysis patients wer...

journal_title：Current medical research and opinion

authors： Gertz B,Kohler E,Kes P,Essaian A,Bias P,Buchner A,Elsässer R

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To compare hypoglycemia event rates in patients initiated on long-acting insulin analog (glargine) or intermediate-acting insulin (NPH) and to analyze the associated cost-consequence from a managed care perspective. STUDY DESIGN:A retrospective analysis of pharmacy and medical claims and electronic laborator...

journal_title：Current medical research and opinion

authors： Bullano MF,Al-Zakwani IS,Fisher MD,Menditto L,Willey VJ

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To compare the analgesic efficacy and safety of oxymorphone extended release (ER) and oxycodone controlled release (CR) in patients with moderate to severe cancer pain. RESEARCH DESIGN AND METHODS:This randomized, multicenter, double-blind, 2-period crossover study included adult outpatients (>or= 18 years o...

journal_title：Current medical research and opinion

authors： Gabrail NY,Dvergsten C,Ahdieh H

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:Early involvement of specialists is associated with improved survival in ovarian cancer patients. However, only 33-60% of patients are currently being referred. A more effective strategy to get patients with an elevated risk of ovarian cancer to gynecologic oncologists is needed. The objective of this study w...

journal_title：Current medical research and opinion

authors： Eskander RN,Carpenter BA,Wu HG,Wolf JK

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:Ramelteon is an MT(1)/MT(2) melatonin receptor agonist indicated for the treatment of insomnia characterized by difficulty with sleep onset. In previous clinical studies, ramelteon reduced latency to persistent sleep (LPS) in subjects with chronic insomnia. The goal of the current analysis was to determine th...

journal_title：Current medical research and opinion

authors： Wang-Weigand S,McCue M,Ogrinc F,Mini L

更新日期：2009-05-01 00:00:00