Mechanisms of HIV-1 neurotropism.

abstract：:Although hepatitis B serology screening has been recommended for HIV care, it has not been routinely performed. We aimed to assess compliance and timing of hepatitis B serology screening among HIV-infected patients in a resource-limited setting. A cross-sectional study was conducted in Thailand. Compliance, timing of ...

journal_title：Current HIV research

authors： Kiertiburanakul S,Chotiprasitsakul D,Atamasirikul K,Sungkanuparph S

更新日期：2011-01-01 00:00:00

abstract：UNLABELLED:Adolescent girls throughout the globe are particularly vulnerable to HIV infection. In the U.S., sexually-active, adolescent girls in urban settings are at elevated risk for HIV. The purpose of this study was to describe a theoreticallydriven, HIV prevention intervention tailored for adolescent girls and eva...

journal_title：Current HIV research

authors： Morrison-Beedy D,Crean HF,Passmore D,Carey MP

更新日期：2013-10-01 00:00:00

abstract：:To assess the correlation between HIV-1 RNA load in blood and semen by antiretroviral therapy status and the relative penetration of antiretroviral drugs in seminal plasma. We performed a cross-sectional cohort study of 119 HIV-1 subjects divided into three groups according to treatment status. Blood and semen were co...

journal_title：Current HIV research

authors： Chan DJ,Ray JE,McNally L,Batterham M,Smith DE

更新日期：2008-09-01 00:00:00

abstract：:After the infusion of HIV-1 virus into a host cell, RNA is reverse transcribed to dsDNA, which persists intracellular to the infected cell in a variety of forms. Numerous in-house assays have been developed for the quantification of the different cellular HIV-1 DNA forms; these implement conventional or real-time PCR ...

journal_title：Current HIV research

authors： Beloukas A,Paraskevis D,Psichogiou M,Hatzakis A

更新日期：2009-05-01 00:00:00

abstract：:In the HAART era Kaposi's sarcoma (KS) remains the second most frequent tumor in HIV-infected patients worldwide, and it has become the most common cancer in Sub-Saharan Africa. In western countries the risk for KS in men having sex with men (MSM) is 5 to 10 times higher compared to other groups of individuals practic...

journal_title：Current HIV research

authors： Martellotta F,Berretta M,Vaccher E,Schioppa O,Zanet E,Tirelli U

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Previous studies have developed methodologies for predicting the number of CD4+ cells from the total leukocyte and lymphocytes count based on mathematical methodologies, obtaining percentages of effectiveness prediction higher than 90% with a value of less than 5000 leukocytes. OBJECTIVE:To improve the meth...

journal_title：Current HIV research

authors： Rodriguez J,Prieto S,Correa C,Melo M,Dominguez D,Olarte N,Suárez D,Aragón L,Torres F,Santacruz F

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Although HIV and injury contribute substantially to disease burdens in lowand middle-income countries (LMIC), their intersection is poorly characterized. OBJECTIVE:This systematic review assessed the prevalence and associated mortality impact of HIVseropositivity among injured patients in LMIC. METHODS:A s...

journal_title：Current HIV research

authors： Aluisio AR,Rege S,Stewart BT,Kinuthia J,Levine AC,Mello MJ,Farquhar C

更新日期：2017-11-23 00:00:00

abstract：:Hodgkin lymphoma (HL) represents one of the most common types of a non-AIDS-defining tumour that occurs in the HIV population, and its incidence is increasing in the post Highly Active Anti-retroviral Therapy (HAART) era. Despite the aggressiveness of that disease, the outcome of patients with HIV-HL has improved with...

journal_title：Current HIV research

authors： Mounier N,Spina M,Spano JP

更新日期：2010-03-01 00:00:00

abstract：:The HIV epidemic has resulted in medical, social and economic consequences. There is general agreement that a safe, effective and affordable preventive HIV vaccine is urgently needed to control the epidemic. To date, over 60 phase I/II trials of about 30 candidate vaccines have been conducted worldwide. In 1991, Thail...

journal_title：Current HIV research

authors： Pitisuttithum P

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Over the years, numerous studies have been carried out demonstrating the role of antibodies in HIV control leading to the development of antibody-based therapeutic and prophylactic strategies. OBJECTIVE:The objective of this review is to provide updated information on the role of antibodies in the preventio...

journal_title：Current HIV research

authors： Fabra-Garcia A,Beltran C,Sanchez-Merino V,Yuste E

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:China has implemented a nation-wide policy to control mother-to-child transmission (MTCT) of the human immunodeficiency virus (HIV) since 2011, yet the efficacy of the control policy is less studied. The aim of the present study was to report the data in the prevention of MTCT of HIV in Nantong city, China. ...

journal_title：Current HIV research

authors： Lou H,Ge X,Xu B,Liu W,Zhou YH

更新日期：2020-01-01 00:00:00

abstract：:Antiretroviral (ARV) prophylaxis for prevention of mother to child transmission (MTCT) of HIV could affect hemoglobin (Hb) development of infants. A cross-sectional descriptive study was conducted in 24 HIV-infected and 21 HIV-uninfected pregnancies. ARV drugs were administered to HIV-infected pregnancies at 21 weeks ...

journal_title：Current HIV research

authors： Pornprasert S,Wongnoi R,Oberdorfer P,Sirivatanapa P

更新日期：2014-01-01 00:00:00

abstract：:Two HIV-1 non B isolates, 98US_MSC5007 and 98US_MSC5016, which have been identified amongst the US Army personnel serving abroad, are known to have originated from other nations. Notwithstanding, they are categorized as American strains. This is because their countries of origin are unknown. American isolates are basi...

journal_title：Current HIV research

authors： Nwankwo N

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Genetic variations in Human leukocyte antigen C (HLA-C), Zinc ribbon domain containing 1 (ZNRD1) and its antisense RNA (ZNRD1-AS1) genes are known to influence the HIV-1 replication and disease progression. OBJECTIVE AND METHOD:We evaluated the distribution of HLA-C (rs10484554, rs9264942) and ZNRD1 (rs8321...

journal_title：Current HIV research

authors： Celerino da Silva R,Moura RR,Victor Campos Coelho A,Arraes LC,Brandão LAC,Crovella S,Lima Guimarães R

更新日期：2017-01-01 00:00:00

abstract：:Natural or experimental infection of the African sooty mangabey (SM) with the simian immunodeficiency virus (SIV) results in chronic high levels of virus replication but is associated with none of the debilitating immunopathology, including the marked CD4 T-cell depletion, persistent cell activation and acquired immun...

journal_title：Current HIV research

authors： Pereira LE,Ansari AA

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The diversity of the HIV proteome influences the cellular response and development of an effective vaccine, particularly due to the generation of viral variants with mutations located within CD8+ T-cell epitopes. These mutations can affect the recognition of the epitopes, that may result in the selection of ...

journal_title：Current HIV research

authors： Acevedo-Saenz L,Perdomo-Celis F,Montoya CJ,Velilla PA

更新日期：2019-01-01 00:00:00

abstract：:A current debate in the HIV-1 vaccine field concerns the ability of an immunodeficiency virus to elicit a protective response. One argument is that HIV-1 superinfections are frequent in healthy individuals, because virus evades conventional immune surveillance, a serious obstacle to vaccine design. The opposing argume...

journal_title：Current HIV research

authors： Sealy R,Zhan X,Lockey TD,Martin L,Blanchard J,Traina-Dorge V,Hurwitz JL

更新日期：2009-09-01 00:00:00

abstract：:According to the World Health Organization's 2007 estimates, close to 33 million people worldwide are living with HIV/AIDS. Over the past two decades, significant progress has been made in understanding HIV pathogenesis and disease progression, which has allowed the identification of a multitude of drug and vaccine ta...

journal_title：Current HIV research

authors： Endsley AN,Salama NN,Ho RJ

更新日期：2008-09-01 00:00:00

abstract：:Interleukin 7 (IL7) is a critical factor for lymphocyte homeostasis. A dysfunction of the IL7/IL7R pathway has previously been described in HIV-1 infection, and promising results were observed in recent analyses of IL7 for therapeutic use in HIV infected individuals. However, further investigations are still warranted...

journal_title：Current HIV research

authors： Limou S,Melica G,Coulonges C,Lelièvre JD,Do H,McGinn S,Gut IG,Lévy Y,Zagury JF

更新日期：2012-03-01 00:00:00

abstract：:One of the major obstacles to effective prolonged CD8 T cell control over HIV and other latent infections may be the intrinsic, genetically programmed barrier to unlimited proliferation that is characteristic of all normal human somatic cells. Replicative senescence, characterized extensively in cell culture for a var...

journal_title：Current HIV research

authors： Effros RB

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:Identifying the genetic variability in vertically transmitted viruses in early infancy is important to understand the disease progression. Being important in HIV-1 disease pathogenesis, vpu gene, isolated from young infants was investigated to understand the viral characteristics. METHOD:Blood samples were o...

journal_title：Current HIV research

authors： Sharma U,Gupta P,Gupta S,Venkatesh S,Husain M

更新日期：2018-01-01 00:00:00

abstract：:The development of pre-exposure prophylactics or microbicide products for the reduction or elimination of the sexual transmission of HIV has numerous challenges or barriers to success. Historically traditional dosage forms such as gels have been developed in the field but more recently controlled release dosage forms ...

journal_title：Current HIV research

authors： Agashe H,Hu M,Rohan L

更新日期：2012-01-01 00:00:00

abstract：:It has been known for decades that exogenous RNAs are able to induce cytotoxic T lymphocytes (CTLs) and immunological reactivity to a wide variety of antigens. The molecular events responsible for these effects remain unclear for more than two decades. It has been decided to revisit this phenomenon in the light of new...

journal_title：Current HIV research

authors： Watanabe MA,de Souza LR,Murad JM,De Lucca FL

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Suboptimal adherence to antiretroviral therapy (ART) is a strong predictor of virologic failure (VF) among people with HIV. Various methods such as patient self-report, pill counts and pharmacy refills have been utilized to monitor adherence. However, there are limited data on the accuracy of combining metho...

journal_title：Current HIV research

authors： Wu P,Johnson BA,Nachega JB,Wu B,Ordonez CE,Hare AQ,Kearns R,Murphy R,Sunpath H,Marconi VC

更新日期：2014-01-01 00:00:00

abstract：UNLABELLED:Some deficient genetic polymorphisms of the innate immune system have been correlated to a higher susceptibility to different infections, especially in immunocompromised patients. The possible association between an increased incidence of pneumococcal bacteremia in HIV-infected patients, and deficient polymo...

journal_title：Current HIV research

authors： Horcajada JP,Lozano F,Muñoz A,Suarez B,Fariñas-Alvarez C,Almela M,Smithson A,Martínez E,Mallolas J,Mensa J,Gatell JM

更新日期：2009-03-01 00:00:00

abstract：:VGV-1, a clinical-grade formulation of bovine thymus nuclear protein (TNP) has been demonstrated to possess anti-viral activity in HIV-1 patients in five clinical trials, one of which was placebo controlled double-blinded. However, to date molecular mechanisms remain to be identified. Using surface plasmon resonance w...

journal_title：Current HIV research

authors： Mamikonyan G,Kiyatkin A,Movsesyan N,Mkrtichyan M,Ghochikyan A,Petrushina I,Hwang J,Ichim TE,Keledjian H,Agadjanyan MG

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:There is scarce information about the molecular epidemiology of HIV-infection in Armenia (former USSR). The objective of this work was to estimate the distribution of HIV-1 subtypes in this country and get any information about HIV drug resistance in naÏve patients. DESIGN:A joint study involving 78 patients...

journal_title：Current HIV research

authors： Laga V,Vasilyev A,Lapovok I,Grigoryan S,Papoyan A,Glushchenko N,Kazennova E,Bobkova M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Manipur is one of the highest HIV prevalence states of India because of its geographical location at the international border near the golden triangle of South-East Asia, but no study on drug resistance associated mutations (DRAMs) has been reported yet. OBJECTIVE:A population-based study on DRAMs of HIV-1 ...

journal_title：Current HIV research

authors： Lakhikumar Sharma A,Ramsing Singh T,Ranjana Devi K,Shanjukumar Singh L

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Despite intense efforts, AIDS is difficult to tackle by current anti-retroviral therapy (ART) due to its side effects; therefore, there is an urgent need to discover potential, multitarget and low-cost anti-HIV compounds. OBJECTIVE:We have shown that few phytocompounds can potentially inhibit the prime targ...

journal_title：Current HIV research

authors： Vora J,Athar M,Sinha S,Jha PC,Shrivastava N

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:Switch to unboosted atazanavir (ATV) is an attractive option due to convenience and tolerability in HIV-positive patients. With limited available data we investigated the determinants of long-term efficacy and the consequences of virological failure of unboosted atazanavir-based regimens. METHODS:Retrospective...

journal_title：Current HIV research

authors： Bonora S,Calcagno A,Vigano O,Bigliano P,Marinaro L,Colella E,Orofino G,Trentini L,Tettoni MC,D'Avolio A,Mercadante S,Galli M,Di Perri G,Rusconi S

更新日期：2014-01-01 00:00:00