Changes in the approach for invasive prenatal diagnosis in 35,127 cases at a single center from 1977 to 2004.

abstract：AIM:To establish normal ranges of maternal placental growth factor (PlGF), soluble fms-like tyrosine kinase-1 (sFlt-1) and sFlt-1/PlGF ratio at 32-41 weeks' gestation and to evaluate the influence of maternal characteristics, and of fetoplacental Doppler. MATERIAL AND METHODS:Serum levels of PlGF, sFlt-1 and sFlt-1/Pl...

journal_title：Fetal diagnosis and therapy

authors： Lobmaier SM,Figueras F,Mercade I,Crovetto F,Peguero A,Parra-Saavedra M,Ortiz JU,Crispi F,Gratacós E

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:There is no precise prenatal indicator to refine an accurate prognosis in case of sacral agenesis and to define the diagnostic approach and outcome criteria in case of fetal sacral agenesis using 3 characteristics of the conus medullaris (CM): its position, its appearance, and associated spinal abnormalities...

journal_title：Fetal diagnosis and therapy

authors： Mottet N,Martinovic J,Baeza C,Guimiot F,Bault JP,Aubry MC,Riethmuller D,Zerah M,Cretolle C,Benachi A

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical and economic impact of adopting noninvasive prenatal testing (NIPT) using circulating cell-free DNA as a first-line screening method for trisomy 21, 18, and 13 in the general pregnancy population. METHODS:A decision-analytical model was developed to assess the impact of adopting NIPT...

journal_title：Fetal diagnosis and therapy

authors： Kostenko E,Chantraine F,Vandeweyer K,Schmid M,Lefevre A,Hertz D,Zelle L,Bartha JL,Di Renzo GC

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Complete congenital high airway obstruction syndrome (CHAOS) usually leads to stillbirth or death within minutes of delivery. We describe the management and long-term follow-up of a baby with a prenatally diagnosed airway obstruction. CASE:Because of progressive hydrops fetalis, massive ascites and everte...

journal_title：Fetal diagnosis and therapy

authors： Paek BW,Callen PW,Kitterman J,Feldstein VA,Farrell J,Harrison MR,Albanese CT

更新日期：2002-09-01 00:00:00

abstract：:Congenital cardiac diverticula are transmural localized protrusions within the free wall of the ventricles. Right ventricular diverticula are rarely diagnosed during the fetal period, and due to their rarity, their natural history remains unclear. We present a case of prenatal diagnosis of right ventricular diverticul...

journal_title：Fetal diagnosis and therapy

authors： Perlitz Y,Mukary M,Lorber A,Ben-Ami M

更新日期：2009-01-01 00:00:00

abstract：:Intrauterine growth restriction (IUGR) is an adverse pregnancy outcome associated with significant perinatal and pediatric morbidity and mortality, and an increased risk of chronic disease later in adult life. While a number of maternal, fetal and environmental factors are known causes of IUGR, the majority of IUGR ca...

journal_title：Fetal diagnosis and therapy

authors： Murthi P,Kalionis B,Rajaraman G,Keogh RJ,Da Silva Costa F

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:The authors conducted a retrospective study of obstetric and genetic data, obstetric problems, and pregnancy outcome by investigating 149 pregnancies of patients who received genetic counselling because of hemophilia A or B over a 20-year period. METHODS:In cases with a heterozygous mother, fetal sex was det...

journal_title：Fetal diagnosis and therapy

authors： Beke A,Bán Z,Nagy B,Tóth-Pál E,Papp C,Csaba A,Papp Z

更新日期：2003-01-01 00:00:00

abstract：:The loss of middle cerebral artery compensatory vasodilation appears to be ominous in fetuses with absent end-diastolic umbilical waveforms. The authors report a case with a loss of the 'brain-sparing effect' 24 h before fetal death. Current pathophysiological explanations are discussed. ...

journal_title：Fetal diagnosis and therapy

authors： Chitrit Y,Zorn B,Filidori M,Bucourt M,Chasseray JE,Caubel P

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVES:To evaluate the prognosis of monochorionic twins with selective intrauterine growth restriction (sIUGR), classified according to the type of umbilical artery Doppler, under expectant management. METHODS:The outcome of 81 cases with isolated sIUGR was evaluated according to a classification based on umbilica...

journal_title：Fetal diagnosis and therapy

authors： Ishii K,Murakoshi T,Takahashi Y,Shinno T,Matsushita M,Naruse H,Torii Y,Sumie M,Nakata M

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:Evidence of meconium-stained amniotic fluid (AF) during labor suggests implementation of close monitoring of fetal well-being. We have investigated whether the presence of meconium in the AF on admission for labor is as important a predictor of neonatal outcome as a change in AF color during labor. METHODS:A...

journal_title：Fetal diagnosis and therapy

authors： Locatelli A,Regalia AL,Patregnani C,Ratti M,Toso L,Ghidini A

更新日期：2005-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine if laterality of an absent umbilical artery (AUA) is associated with specific sonographic findings, chromosomal defects or postpartum birth defects. MATERIALS AND METHODS:In this retrospective cohort study, ultrasound reports and medical records of patients who recei...

journal_title：Fetal diagnosis and therapy

authors： Santillan M,Santillan D,Fleener D,Stegmann B,Zamba G,Hunter S,Yankowitz J

更新日期：2012-01-01 00:00:00

abstract：:Although δ-globin gene mutations have no clinical implications, association of β- and δ-thalassemia may lead to misdiagnosis. We describe the case of a Chinese woman who was assumed to have an α-thalassemia heterozygote, but was later shown to have β-thalassemia with a normal amount of HbA(2) caused by the -77 mutatio...

journal_title：Fetal diagnosis and therapy

authors： Li J,Xie XM,Zhou JY,Li DZ

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:To compare the DELFIA Xpress and Quantikine ELISA placental growth factor (PlGF) immunoassay platforms by analysing the same set of early first-trimester maternal serum samples from cases with trisomy 21 and euploid controls. METHODS:Thirty-seven trisomy 21 cases and 243 euploid control serum samples, drawn...

journal_title：Fetal diagnosis and therapy

authors： Cowans NJ,Kisanga M,Khan A,Spencer K

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To evaluate pre-intervention echocardiographic parameters of cardiac function in fetuses who survive without hydrops as compared to fetuses who develop hydrops or perinatal death in the setting of sacrococcygeal teratoma (SCT) and twin-reversed arterial perfusion sequence (TRAP). METHODS:Clinical, echocardio...

journal_title：Fetal diagnosis and therapy

authors： Byrne FA,Lee H,Kipps AK,Brook MM,Moon-Grady AJ

更新日期：2011-01-01 00:00:00

abstract：:Total anomalous pulmonary venous return (TAPVR) is a congenital heart malformation that can be diagnosed in the fetus by indirect indicators on an echocardiogram, such as inability to demonstrate the pulmonary veins returning to the left atrium by color Doppler, the presence of a chamber or the pulmonary venous conflu...

journal_title：Fetal diagnosis and therapy

authors： Cormier CM,Kramer LA,Gupta-Malhotra M

更新日期：2010-01-01 00:00:00

abstract：:The objectives of the study were to assess the ability of a fetal pulse oximeter to measure the fetal oxygen saturation (SPO2) continuously during labor and to assess the correlation between readings of fetal pulse oximetry and cord blood gases at birth. The Nellcor N-400 Fetal Oximeter was used in 62 women prospectiv...

journal_title：Fetal diagnosis and therapy

authors： Langer B,Boudier E,Haddad J,Pain L,Schlaeder G

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine the potential of human embryonic stem (hES) cells to provide an in vitro model of human extraembryonic endoderm development. METHODS:The hES cell line HES-2 was propagated in Dulbecco's modification of Eagle's medium (DMEM) in the presence of 20% fetal calf serum ...

journal_title：Fetal diagnosis and therapy

authors： Conley BJ,Trounson AO,Mollard R

更新日期：2004-05-01 00:00:00

abstract：:Acute hydramnios is a rare complication of pregnancy, usually of idiopathic etiology and associated with a very poor perinatal prognosis. In this single case report, acute hydramnios at 21 weeks' gestation, associated with fetal CMV infection, was treated by a single large volume reduction amniocentesis combined with ...

journal_title：Fetal diagnosis and therapy

authors： Bondagji N,Manning FA,Martel J,Harman CR,Morrison I

更新日期：1996-09-01 00:00:00

abstract：:Five postmortem fetuses were scanned by magnetic resonance (MR) imaging. Of eight three-dimensional (3D) data sets reconstructed on an MGI workstation, five sets demonstrated detailed 3D fetal cardiac structures, and one depicted clear information regarding the disposition and compression of the heart and lungs in dia...

journal_title：Fetal diagnosis and therapy

authors： Deng J,Brookes JA,Gardener JE,Rodeck CH,Lees WR

更新日期：1996-11-01 00:00:00

abstract：INTRODUCTION:The purpose of this study was to obtain precise knowledge of fetal biometric measurements, in particular crown-rump length (CRL). Our results have been carefully compared to equations found in the literature. MATERIALS AND METHODS:Single-operator measurements of 2,123 spontaneous pregnancies from a genera...

journal_title：Fetal diagnosis and therapy

authors： Constant M,Tran VC,Benoit B,Vasseur F

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:This study describes the association between the complexity of congenital cardiac and extracardiac malformations, and the parental decision of pregnancy continuation or termination. METHODS:Congenital heart defects (CHD) was diagnosed by ultrasound in 251 fetuses before the 24th week (23 + 6 weeks) of gestat...

journal_title：Fetal diagnosis and therapy

authors： Nell S,Wijngaarde CA,Pistorius LR,Slieker M,ter Heide H,Manten GT,Freund MW

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Beckwith-Wiedemann syndrome (BWS) is a distinct clinical syndrome with unique features, generally diagnosed postnatally. CASE:A 26-year-old patient, gravida 4, para 3-0-0-3, was noted to have an abnormal maternal serum screen. Amniocentesis with imaging studies were remarkable only for a two-vessel umbilica...

journal_title：Fetal diagnosis and therapy

authors： Aagaard-Tillery KM,Buchbinder A,Boente MP,Ramin KD

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:In intrauterine growth restriction (IUGR), increased uteroplacental vascular impedance contributes to preferential flow to left ventricle (LV), with consequent alteration of its compliance and increased left atrial (LA) pressure. Pulmonary vein pulsatility index (PVPI) reflects the increased impedance to L...

journal_title：Fetal diagnosis and therapy

authors： Bravo-Valenzuela NJM,Zielinsky P,Zurita-Peralta J,Nicoloso LH,Piccoli A Jr,Ferreira Van der Sand L,Miranda Sulis N,Carvalho Ritter C

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Myelomeningocele is a neural tube defect resulting in an exposed spinal cord, which leads to irreversible neurologic damage at birth. We proposed development of a fetal rabbit model of myelomeningocele to study in utero spinal cord injury and repair strategies. METHODS:New Zealand white rabbits (n = 10) at 2...

journal_title：Fetal diagnosis and therapy

authors： Housley HT,Graf JL,Lipshultz GS,Calvano CJ,Harrison MR,Farmer DL,Jennings RW

更新日期：2000-09-01 00:00:00

abstract：:Reproductive genetic testing technologies are expanding at an exponential rate. Nurses are increasingly being called upon to provide these services to women. This paper discusses the status of nursing education in genetics and identifies immediate needs for nurses in order to be adequately prepared to respond to these...

journal_title：Fetal diagnosis and therapy

authors： Thomson EJ

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Fetal growth may vary significantly in different congenital heart defects (CHDs). OBJECTIVES:To investigate prenatal growth of CHD fetuses and its correlation with classifications based upon expected oxygen delivery to the fetal brain or structural findings. METHODS:Seventy-nine euploid fetuses with isolat...

journal_title：Fetal diagnosis and therapy

authors： Inversetti A,Fesslova V,Deprest J,Candiani M,Giorgione V,Cavoretto P

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:A diagnosis of myocardial dystrophic calcification, a rare cause of fetal cardiac masses, is presented. METHODS:The fetal echocardiography of a 26-year-old pregnant woman who was referred to the Pediatric Cardiology Department at 20 weeks' gestation revealed an echogenic mass in the post wall of the left ven...

journal_title：Fetal diagnosis and therapy

authors： Baysal K,Haciomeroglu P,Sungur M,Köse B,Kandemir B

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To determine whether the incidence of pregnancies complicated by meconium-stained amniotic fluid (MSAF) or meconium aspiration syndrome (MAS) differs with seasonal changes. METHODS:An established perinatal database was used to identify all term (> or = 37 weeks) singleton gestations resulting in a live birth...

journal_title：Fetal diagnosis and therapy

authors： Blackwell SC,Carreno CA,Hassan SS,Moldenhauer J,Wolfe HM,Berry SM,Kruger M,Sorokin Y

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to create an animal model of obstructive ventriculomegaly in the fetal lamb at 78 days of gestation by injecting maternal blood into the lateral ventricles under ultrasound guidance. METHODS:An endoscope of 1.2 mm housed in a 1.6-mm trocar was introduced into the dilated lateral ven...

journal_title：Fetal diagnosis and therapy

authors： De Keersmaecker B,Vloeberghs M,Ville Y

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To evaluate lower extremity neuromotor function (LENF) and short-term ambulatory potential following fetal myelomeningocele (fMMC) closure. METHODS:Retrospective chart review of 54 children that underwent fMMC closure at our institution prior to the NIHCD-MOMS trial. Neonatal LENF was compared to predicted f...

journal_title：Fetal diagnosis and therapy

authors： Danzer E,Gerdes M,Bebbington MW,Sutton LN,Melchionni J,Adzick NS,Wilson RD,Johnson MP

更新日期：2009-01-01 00:00:00