Abstract:
INTRODUCTION:In intrauterine growth restriction (IUGR), increased uteroplacental vascular impedance contributes to preferential flow to left ventricle (LV), with consequent alteration of its compliance and increased left atrial (LA) pressure. Pulmonary vein pulsatility index (PVPI) reflects the increased impedance to LA filling and could be used as a cardiac monitoring parameter in IUGR. MATERIAL AND METHODS:A total of 27 IUGR fetuses (group 1), 28 fetuses with appropriate growth for gestational age from hypertensive mothers (group 2), and 28 controls (group 3) were studied. Pulsatility indices (PIs) of pulmonary veins and ductus venosus were calculated by Doppler echocardiography. Obstetric ultrasound was used to assess the PIs of uterine, umbilical, and middle cerebral arteries. Statistical analysis used analysis of variance, post-hoc Tukey, and Pearson's tests. RESULTS:Mean PVPI was higher in IUGR group (1.27 ± 0.39) when compared to groups 2 (1.02 ± 0.37; p = 0.01) and 3 (0.75 ± 0.12; p < 0.001). In group 2, moderate correlation between PVPI and ductus venosus pulsatility index (DVPI) was found but not between PVPI and cerebroplacental ratio (CPR). DISCUSSION:Higher PVPI in IUGR reflects decreased LV compliance and altered LA dynamics. As LV dysfunction precedes right ventricle, our results suggest that PVPI could be an early echocardiographic parameter of fetal diastolic function in IUGR.
journal_name
Fetal Diagn Therjournal_title
Fetal diagnosis and therapyauthors
Bravo-Valenzuela NJM,Zielinsky P,Zurita-Peralta J,Nicoloso LH,Piccoli A Jr,Ferreira Van der Sand L,Miranda Sulis N,Carvalho Ritter Cdoi
10.1159/000488281subject
Has Abstractpub_date
2019-01-01 00:00:00pages
205-211issue
4eissn
1015-3837issn
1421-9964pii
000488281journal_volume
45pub_type
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journal_title:Fetal diagnosis and therapy
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journal_title:Fetal diagnosis and therapy
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章,评审
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journal_title:Fetal diagnosis and therapy
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更新日期:2015-01-01 00:00:00
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journal_title:Fetal diagnosis and therapy
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doi:10.1159/000263946
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journal_title:Fetal diagnosis and therapy
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章
doi:10.1159/000080158
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journal_title:Fetal diagnosis and therapy
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journal_title:Fetal diagnosis and therapy
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doi:10.1159/000263628
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journal_title:Fetal diagnosis and therapy
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doi:10.1159/000048032
更新日期:2002-05-01 00:00:00
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章
doi:10.1159/000342418
更新日期:2013-01-01 00:00:00
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章
doi:10.1159/000074262
更新日期:2004-01-01 00:00:00
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journal_title:Fetal diagnosis and therapy
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doi:10.1159/000263748
更新日期:1993-01-01 00:00:00
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章
doi:10.1159/000489124
更新日期:2019-01-01 00:00:00
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章,评审
doi:10.1159/000020840
更新日期:1998-07-01 00:00:00
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journal_title:Fetal diagnosis and therapy
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doi:10.1159/000265554
更新日期:2009-01-01 00:00:00
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journal_title:Fetal diagnosis and therapy
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doi:10.1159/000077959
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章
doi:10.1159/000263904
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章,多中心研究
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更新日期:2018-01-01 00:00:00
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章
doi:10.1159/000264358
更新日期:1996-11-01 00:00:00
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章
doi:10.1159/000488280
更新日期:2019-01-01 00:00:00
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章
doi:10.1159/000063179
更新日期:2002-09-01 00:00:00
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journal_title:Fetal diagnosis and therapy
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更新日期:1997-07-01 00:00:00
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journal_title:Fetal diagnosis and therapy
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
doi:10.1159/000335028
更新日期:2012-01-01 00:00:00