Meconium staining and meconium aspiration syndrome. Is there seasonal variation?

Abstract:

OBJECTIVE:To determine whether the incidence of pregnancies complicated by meconium-stained amniotic fluid (MSAF) or meconium aspiration syndrome (MAS) differs with seasonal changes. METHODS:An established perinatal database was used to identify all term (> or = 37 weeks) singleton gestations resulting in a live birth from January 1, 1997 to December 31, 1999. Patients were divided into groups based on the season of delivery: winter (December-February), spring (March-May), summer (June-August), and fall (September-November). Rates of MSAF (%MSAF/total deliveries) and MAS (%MAS/total deliveries) were calculated and compared among seasons. Local climatic data (average monthly temperature and monthly precipitation) were obtained from the National Weather Service. Multiple logistic regression analysis was performed to control for the effects of confounding variables and odds ratio (OR) with 95% confidence intervals (CI) were calculated. p < 0.05 was considered significant. RESULTS:Over the 3-year study period there were a total of 14,888 deliveries meeting the criteria. MSAF occurred in 3,206 (21.5%) deliveries and MAS developed in 92 (0.6% of total, 2.9% of MSAF). There were no differences in the rate of MSAF (p = 0.2) or MAS (p = 0.6) between seasons. By logistic regression neither season, temperature, nor precipitation were associated with MSAF or MAS. CONCLUSIONS:Our findings suggest that over the period examined there were no significant seasonal variations in the incidence of MSAF or MAS.

journal_name

Fetal Diagn Ther

authors

Blackwell SC,Carreno CA,Hassan SS,Moldenhauer J,Wolfe HM,Berry SM,Kruger M,Sorokin Y

doi

10.1159/000053911

keywords:

subject

Has Abstract

pub_date

2001-07-01 00:00:00

pages

208-10

issue

4

eissn

1015-3837

issn

1421-9964

pii

53911

journal_volume

16

pub_type

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