Prognostic value of change in amniotic fluid color during labor.

Abstract:

OBJECTIVE:Evidence of meconium-stained amniotic fluid (AF) during labor suggests implementation of close monitoring of fetal well-being. We have investigated whether the presence of meconium in the AF on admission for labor is as important a predictor of neonatal outcome as a change in AF color during labor. METHODS:AF characteristics on admission for labor at term (37-42 weeks) and their changes during labor were recorded in all singleton pregnancies during an 8-year period (1992-1999). Excluded were stillbirths on admission, congenital anomalies, and elective cesarean sections. The presence of meconium and its consistency (light or thick) were documented on admission by inspection with transcervical amnioscopy in women with intact membranes or in the vaginal pool in those with ruptured membranes. Changes in AF color or consistency during labor were recorded and correlated with the obstetric and neonatal outcome. Statistical analysis utilized chi(2) for trend, with p < 0.05 considered significant. RESULTS:19,090 women were admitted in labor at term during the study period and fulfilled the study inclusion criteria and had amniotic fluid evaluation available. The appearance of meconium or worsening in thickness of meconium during labor was associated with higher rates of Apgar scores <7 at 5 min (clear AF on admission and at delivery 0.6%; light or thick meconium on admission and no change at delivery 0.8%; clear AF on admission and light or thick meconium at delivery 3.2%, and light meconium on admission and thick meconium at delivery 2.5%; p < 0.001) and umbilical artery pH <7.10 (the respective rates in the four groups were 1.7, 1.8, 3.6, and 3.8%; p < 0.001). CONCLUSION:The appearance or thickening of meconium during labor has a greater predictive ability for depressed neonates than the presence of meconium on admission.

journal_name

Fetal Diagn Ther

authors

Locatelli A,Regalia AL,Patregnani C,Ratti M,Toso L,Ghidini A

doi

10.1159/000081359

keywords:

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

5-9

issue

1

eissn

1015-3837

issn

1421-9964

pii

81359

journal_volume

20

pub_type

杂志文章
  • The early amniocentesis study: a randomized clinical trial of early amniocentesis and midtrimester amniocentesis. II. Evaluation of procedure details and neonatal congenital anomalies.

    abstract::The present study provides detailed neonatal and congenital malformation follow-up from 695 women enrolled in a prospective randomized multicenter study comparing the safety and accuracy of early (11-12 weeks of gestation) and midtrimester amniocentesis (15-16 weeks of gestation). No differences were found for total p...

    journal_title:Fetal diagnosis and therapy

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1159/000264440

    authors: Wilson RD,Johnson J,Windrim R,Dansereau J,Singer J,Winsor EJ,Kalousek D

    更新日期:1997-03-01 00:00:00

  • Hemimegalencephaly: 2D, 3D Ultrasound and MRI Correlation.

    abstract:BACKGROUND:Hemimegalencephaly (HMC) is a disorder associated with enlarged and dysplastic hamartomatous overgrowth of all or part of the one cerebral hemisphere that can be isolated or associated with other syndromes. In the normal development of the brain it is important to bear in mind that there are two main process...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000322012

    authors: Romero XC,Molina FS,Pastor E,Amaya F

    更新日期:2011-01-01 00:00:00

  • Assessment of fetal cardiac function using tissue Doppler techniques.

    abstract:OBJECTIVE:Tissue Doppler echocardiography is being increasingly used in fetal medicine as a clinical and research tool. The objective of this study was to review the current status of tissue Doppler imaging (TDI) techniques applied to the fetus. METHODS:Fetal cardiac function was evaluated using spectral and color TDI...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000335028

    authors: Comas M,Crispi F

    更新日期:2012-01-01 00:00:00

  • On the complication risk of early amniocentesis versus standard amniocentesis.

    abstract::In the last 6 years early amniocentesis for the prenatal diagnosis of chromosome aberrations has been established in many centers worldwide, but knowledge about the gynecological safety of the procedure is sparse. From 1990 to 1995 at the Evangelisches Krankenhaus Oberhausen (Germany) 3,277 early amniocenteses (betwee...

    journal_title:Fetal diagnosis and therapy

    pub_type: 临床试验,杂志文章

    doi:10.1159/000264454

    authors: Eiben B,Hammans W,Hansen S,Trawicki W,Osthelder B,Stelzer A,Jaspers KD,Goebel R

    更新日期:1997-05-01 00:00:00

  • Diagnosis and management of Rh alloimmunization.

    abstract:OBJECTIVE:To assess the current problem of alloimmunization in a tertiary referral center in Croatia. The results obtained were compared to data published worldwide. METHODS:Retrospective case analysis included women with Rhesus (Rh) alloimmunization treated in our department from January 1997 to January 2003. Data of...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000086819

    authors: Matijevic R,Grgic O,Klobucar A,Miskovic B

    更新日期:2005-09-01 00:00:00

  • Perinatal outcomes following the ultrasound diagnosis of echogenic bowel: an Australian perspective.

    abstract:INTRODUCTION:The aim of this study was to describe the association between fetal echogenic bowel (FEB) diagnosed during the second trimester and adverse perinatal outcomes in an Australian antenatal population. METHODS:A retrospective analysis of ultrasound scans was performed between March 1, 2004 and March 1, 2009 a...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000336123

    authors: Ameratunga DM,Said JM,Reidy K,Palma-Dias R

    更新日期:2012-01-01 00:00:00

  • Evaluation of prolonged fetal monitoring with normal and pathologic outcome probabilities determined by artificial neural network.

    abstract:OBJECTIVE:The purpose of this study was to objectively evaluate prolonged fetal heart rate (FHR) monitoring, which has been difficult to do with conventional cardiotocogram (CTG). METHODS:FHR was analyzed by an artificial neural network computer that calculates probabilities of normal, pathologic and suspicious outcom...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000071982

    authors: Maeda K,Noguchi Y,Matsumoto F

    更新日期:2003-09-01 00:00:00

  • Fetal hydrocephalus and intrauterine cerebral ventriculoscopy: an animal model.

    abstract:OBJECTIVE:The aim of this study was to create an animal model of obstructive ventriculomegaly in the fetal lamb at 78 days of gestation by injecting maternal blood into the lateral ventricles under ultrasound guidance. METHODS:An endoscope of 1.2 mm housed in a 1.6-mm trocar was introduced into the dilated lateral ven...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000086829

    authors: De Keersmaecker B,Vloeberghs M,Ville Y

    更新日期:2005-09-01 00:00:00

  • Long-Term Outcome of Monochorionic Twins after Fetoscopic Laser Therapy Compared to Matched Dichorionic Twins.

    abstract:INTRODUCTION:The only causal therapy is fetoscopic laser surgery (FLS). The aims of this study were to analyze the long-term outcome of monochorionic twins treated by FLS, including their school career, need for therapy and special aid equipment, and free-time activities, and compare their outcome to matched dichorioni...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000509400

    authors: Rüegg L,Hüsler M,Krähenmann F,Zimmermann R,Natalucci G,Ochsenbein-Kölble N

    更新日期:2020-01-01 00:00:00

  • Quantification of Posterior Risk Related to Intrapartum FIGO 2015 Criteria for Cardiotocography in the Second Stage of Labor.

    abstract:INTRODUCTION:Intrapartum cardiotocography (CTG) was used for several decades to detect a stressed fetus so that delivery can be expedited to prevent birth asphyxia. The main aim of the study was to calculate the risk of neonatal acidemia (pH ≤ 7.10) according to duration of the 2nd stage of labor and occurrence of the ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000512658

    authors: Cavoretto PI,Seidenari A,Amodeo S,Della Gatta AN,Nale R,Ismail YS,Candiani M,Farina A

    更新日期:2021-01-28 00:00:00

  • Perinatal outcome of conservative management versus fetal intervention for twin reversed arterial perfusion sequence with a small acardiac twin.

    abstract:OBJECTIVE:To examine the outcomes of patients with twin reversed arterial perfusion (TRAP) sequence in which the acardiac twin was

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000295176

    authors: Jelin E,Hirose S,Rand L,Curran P,Feldstein V,Guevara-Gallardo S,Jelin A,Gonzales K,Goldstein R,Lee H

    更新日期:2010-01-01 00:00:00

  • Percutaneous Intratumor Laser Ablation for Fetal Sacrococcygeal Teratoma.

    abstract:OBJECTIVE:To evaluate the efficiency of percutaneous intratumor laser ablation for fetal solid sacrococcygeal teratoma (SCT). SUBJECTS AND METHODS:We carried out percutaneous ultrasound-guided intratumor laser ablation through a 17-gauge needle using an output of 40 W in 7 fetuses with large solid SCT and reviewed the...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000500775

    authors: Litwińska M,Litwińska E,Janiak K,Piaseczna-Piotrowska A,Szaflik K

    更新日期:2020-01-01 00:00:00

  • Amnioinfusion with Hartmann's solution: a safe distention medium for endoscopic fetal surgery in the ovine model.

    abstract::In this study, we have investigated the maternal effects of distending the uterine cavity with Hartmann's solution in 2nd trimester equivalent pregnant sheep. In 7 pregnant ewes, double endoscopic cannulation of the amniotic cavity was performed under general anesthesia, and 1 liter of Hartmann's solution at 38 degree...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000264464

    authors: Evrard VA,Verbeke K,Peers KH,Luks FI,Lerut AE,Vandenberghe K,Deprest JA

    更新日期:1997-05-01 00:00:00

  • Complete resolution of CMV-associated acute hydramnios by single large volume reduction amniocentesis and maternal indomethacin. A case report.

    abstract::Acute hydramnios is a rare complication of pregnancy, usually of idiopathic etiology and associated with a very poor perinatal prognosis. In this single case report, acute hydramnios at 21 weeks' gestation, associated with fetal CMV infection, was treated by a single large volume reduction amniocentesis combined with ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000264339

    authors: Bondagji N,Manning FA,Martel J,Harman CR,Morrison I

    更新日期:1996-09-01 00:00:00

  • The role of integrins in human embryo implantation.

    abstract::Integrins are adhesion molecules present in endometrial, decidual, and extravillous cytotrophoblast (EVCT) cells. They participate in cell-cell adhesion as well as in adhesion between cells and components of the extracellular matrix, and they play an important role in the endometrial phenotype change that occurs durin...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000053942

    authors: Merviel P,Challier JC,Carbillon L,Foidart JM,Uzan S

    更新日期:2001-11-01 00:00:00

  • Neurodevelopmental Effects of Undernutrition and Placental Underperfusion in Fetal Growth Restriction Rabbit Models.

    abstract:INTRODUCTION:Chronic reduction of oxygen and nutrient delivery to the fetus has been related to neurodevelopmental problems. Placental underperfusion induces a significant reduction in oxygen and nutrient delivery, whereas maternal undernutrition causes mainly nutrient deficiency. A comparison of the neurodevelopmental...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000454859

    authors: Illa M,Eixarch E,Muñoz-Moreno E,Batalle D,Leal-Campanario R,Gruart A,Delgado-García JM,Figueras F,Gratacós E

    更新日期:2017-01-01 00:00:00

  • Venous-arterial Doppler ratios in the prediction of acidemia at birth in pregnancies with placental insufficiency.

    abstract:OBJECTIVES:Investigate the prediction of birth acidemia in pregnancies with placental insufficiency using two newly created venous-arterial Doppler ratios: pulsatility index (PI) of the ductus venosus (DV) over PI of the middle cerebral artery (MCA) and PI of the DV over PI of the umbilical artery and establish cut-off...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000093883

    authors: Carvalho FH,Moron AF,Mattar R,Murta CG,Santana RM,Barbosa MM,Torloni MR,Vasques FA

    更新日期:2006-01-01 00:00:00

  • Lung function following first-trimester amniocentesis or chorion villus sampling.

    abstract::Functional residual capacity (FRC) was measured at 2-8 (median 4) weeks of age in 100 infants whose mothers had entered a randomized trial of amniocentesis versus chorion villus sampling (CVS) at 10-13 weeks gestation. At measurement all of the infants were well and none had respiratory problems. No significant differ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000263638

    authors: Thompson PJ,Greenough A,Nicolaides KH

    更新日期:1991-01-01 00:00:00

  • Fetal goitrous hypothyroidism followed by neonatal transient hyperthyroidism. A case report.

    abstract::We report a case of fetal goitrous hypothyroidism followed by neonatal transient hyperthyroidism. A fetal goiter (26 x 38 mm) was detected by ultrasound and magnetic resonance imaging at 29 weeks of gestation. Hypothyroidism was confirmed by cordocentesis, which revealed an elevated TSH (255 microIU/ml) and a low free...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000073143

    authors: Matsumoto T,Miyakoshi K,Kasai K,Ishimoto H,Tanaka M,Ikeda K,Yoshimura Y

    更新日期:2003-11-01 00:00:00

  • Thoraco-omphalopagus conjoined twins detected at as early as 9 weeks of gestation: transvaginal two-dimensional ultrasound, color Doppler and fetoplacental Doppler velocity waveform findings.

    abstract::Here we report a case of conjoined twins that were diagnosed antenatally by routine two-dimensional transvaginal ultrasound examination at as early as the 9th week of gestational age. The fetuses were of the thoraco-omphalopagus type and were sharing the liver, as confirmed by color Doppler. There was a reversed flow ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000093893

    authors: Basgül A,Kavak ZN,Sezen D,Basgul A,Gokaslan H

    更新日期:2006-01-01 00:00:00

  • Debate about ultrasound screening policies.

    abstract::Routine ultrasound examination is defined as a screening procedure performed on the total obstetric population usually at 18-20 weeks of gestation as opposed to the selective use of ultrasound that might provide more information for a problem that is suspected on clinical grounds. Standard ultrasound examination inclu...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000020840

    authors: Antsaklis AJ

    更新日期:1998-07-01 00:00:00

  • Why cell culture is successful after early amniocentesis.

    abstract::The current interest in early amniocentesis as a possible alternative to chorion villus sampling has driven many centres to attempt cell culture from first trimester amniotic fluid. This study examines the cellular content of 125 amniotic fluid specimens collected between 8 and 18 weeks of gestation and shows that the...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000263628

    authors: Byrne D,Azar G,Nicolaides K

    更新日期:1991-01-01 00:00:00

  • Amniotic fluid pressure in both cavities of twin-to-twin transfusion syndrome: a vote against septostomy.

    abstract:OBJECTIVE:To report our results of the measurement of the amniotic fluid pressure in twin-to-twin transfusion syndrome before and after amniodrainage and the separate measurement in the cavity of the stuck twin and the recipient, respectively, in 2 cases. METHOD:Six patients with severe TTS underwent therapeutic amnio...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000020980

    authors: Hartung J,Chaoui R,Bollmann R

    更新日期:2000-03-01 00:00:00

  • An ethically justified decision-making pathway for the management of pregnancies complicated by twin-to-twin transfusion syndrome.

    abstract:OBJECTIVE:To present an ethically justified decision-making pathway to use in the evaluation and treatment of pregnant women whose fetuses have twin-to-twin transfusion syndrome (TTTS). METHODS:The ethical principles of beneficence, autonomy and professional integrity were applied to the diagnostic and treatment optio...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000103292

    authors: Skupski D,Chervenak FA,McCullough L

    更新日期:2007-01-01 00:00:00

  • Changes in blood flow velocity waveforms following fetal blood sampling.

    abstract::The umbilical artery, aorta, and middle cerebral artery pulsatility indices were investigated by pulsed Doppler ultrasound in 73 fetuses at 18-37 weeks of gestation, before and after fetal blood sampling performed either at the placental cord insertion (n = 46) or at the intrahepatic vein (n = 27). At the end of the p...

    journal_title:Fetal diagnosis and therapy

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000264251

    authors: Zoppini C,Brioschi D,Tassis B,Zuliani G,Kustermann A,Nicolini U

    更新日期:1995-09-01 00:00:00

  • Enrichment of fetal nucleated red blood cells from the maternal circulation for prenatal diagnosis: experiences with triple density gradient and MACS based on more than 600 cases.

    abstract:OBJECTIVE:We wanted to obtain statistically relevant data about the efficiency of our method for the isolation of fetal nucleated red blood cells (NRBCs) from the maternal circulation. METHODS:More than 600 samples were investigated using a triple density gradient followed by magnetic separation of anti-CD71-labeled c...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000020854

    authors: Gänshirt D,Smeets FW,Dohr A,Walde C,Steen I,Lapucci C,Falcinelli C,Sant R,Velasco M,Garritsen HS,Holzgreve W

    更新日期:1998-09-01 00:00:00

  • Severe hyperbilirubinemia in a glucose-6-phosphate dehydrogenase-deficient preterm neonate: could prematurity be the main responsible factor?

    abstract::We report on a premature infant with glucose-6-phosphate dehydrogenase deficiency and severe hyperbilirubinemia. In this patient, all known potential hemolytic agents were excluded and no findings of hemolysis were observed. The crucial role of prematurity in the pathogenesis of this type of jaundice is discussed. ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000174571

    authors: Costa S,De Carolis MP,De Luca D,Savarese I,Romagnoli C

    更新日期:2008-01-01 00:00:00

  • Ehlers-Danlos type IV in pregnancy. A case report and a literature review.

    abstract:BACKGROUND:Ehlers-Danlos syndrome is a heterogeneous group of connective tissue disorders, characterized by a defect in the synthesis of collagen. The syndrome is subdivided into different clinical subtypes, the most hazardous of which is type IV, the vascular type. It can manifest itself in various complications such ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000109218

    authors: Erez Y,Ezra Y,Rojansky N

    更新日期:2008-01-01 00:00:00

  • Increased nuchal translucency in a case of long-chain 3-hydroxyacyl- coenzyme A dehydrogenase deficiency.

    abstract::We present a case where the embryo showed an increased nuchal edema and a metabolic disorder. At 31 weeks of gestation the fetus developed a cardiomegaly and a hydrops. In this case, a long-chain 3-hydroxacyl-coenzyme A dehydrogenase deficiency (LCHAD deficiency) was confirmed by biochemical investigations in cultured...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000021029

    authors: Tercanli S,Uyanik G,Hösli I,Cagdas A,Holzgreve W

    更新日期:2000-11-01 00:00:00

  • Bidirectional communication between neural and cardiac cells in human amniotic fluid.

    abstract:OBJECTIVE:To evaluate whether amniotic fluid cells contain cardiomyocyte- and neuron-like cells. STUDY DESIGN:In this experimental study, cells from human amniotic fluid samples were analyzed for mRNA expression of microtubule-associated protein 2 (MAP-2), vimentin and oxytocin (OT) receptor via RT-PCR. Immunocytochem...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000200016

    authors: Stefanidis K,Loutradis D,Anastasiadou V,Dinopoulou V,Eleni E,Arampatzi E,Lekka K,Mesogitis S,Antsaklis A

    更新日期:2009-01-01 00:00:00