Venous-arterial Doppler ratios in the prediction of acidemia at birth in pregnancies with placental insufficiency.

Abstract:

OBJECTIVES:Investigate the prediction of birth acidemia in pregnancies with placental insufficiency using two newly created venous-arterial Doppler ratios: pulsatility index (PI) of the ductus venosus (DV) over PI of the middle cerebral artery (MCA) and PI of the DV over PI of the umbilical artery and establish cut-off values for this prediction. METHODS:This was a prospective cross-sectional study involving 47 patients with placental insufficiency managed in two Brazilian hospitals. All pregnancies were singleton, over 26 weeks of age and without structural or chromosome anomalies. A ROC curve was calculated for the venous-arterial ratios (independent variable) and acidemia (dependent variable). RESULTS:The DV/AU PI ratio was not a good predictor of acidemia at birth. The DV/MCA PI ratio was related to fetal acidemia (area under the ROC curve 0.785, p = 0.004). The cut-off value was 0.582, sensibility 66.7%, specificity 77.1% and accuracy 74.5%. CONCLUSIONS:The DV/MCA PI ratio is adequate for the diagnosis of acidemia at birth in pregnancies with placental insufficiency. The cut-off value was 0.582.

journal_name

Fetal Diagn Ther

authors

Carvalho FH,Moron AF,Mattar R,Murta CG,Santana RM,Barbosa MM,Torloni MR,Vasques FA

doi

10.1159/000093883

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

418-23

issue

5

eissn

1015-3837

issn

1421-9964

pii

93883

journal_volume

21

pub_type

杂志文章
  • Single umbilical artery: Does side matter?

    abstract:INTRODUCTION:The aim of this study was to determine if laterality of an absent umbilical artery (AUA) is associated with specific sonographic findings, chromosomal defects or postpartum birth defects. MATERIALS AND METHODS:In this retrospective cohort study, ultrasound reports and medical records of patients who recei...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000338133

    authors: Santillan M,Santillan D,Fleener D,Stegmann B,Zamba G,Hunter S,Yankowitz J

    更新日期:2012-01-01 00:00:00

  • Severe hyperbilirubinemia in a glucose-6-phosphate dehydrogenase-deficient preterm neonate: could prematurity be the main responsible factor?

    abstract::We report on a premature infant with glucose-6-phosphate dehydrogenase deficiency and severe hyperbilirubinemia. In this patient, all known potential hemolytic agents were excluded and no findings of hemolysis were observed. The crucial role of prematurity in the pathogenesis of this type of jaundice is discussed. ...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000174571

    authors: Costa S,De Carolis MP,De Luca D,Savarese I,Romagnoli C

    更新日期:2008-01-01 00:00:00

  • Neurodevelopmental Effects of Undernutrition and Placental Underperfusion in Fetal Growth Restriction Rabbit Models.

    abstract:INTRODUCTION:Chronic reduction of oxygen and nutrient delivery to the fetus has been related to neurodevelopmental problems. Placental underperfusion induces a significant reduction in oxygen and nutrient delivery, whereas maternal undernutrition causes mainly nutrient deficiency. A comparison of the neurodevelopmental...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000454859

    authors: Illa M,Eixarch E,Muñoz-Moreno E,Batalle D,Leal-Campanario R,Gruart A,Delgado-García JM,Figueras F,Gratacós E

    更新日期:2017-01-01 00:00:00

  • A case of fetal complete heart block recorded by magnetocardiography, ultrasonography and direct fetal electrocardiography.

    abstract::Fetal magnetocardiograms (FMCGs) were recorded in a case of fetal complete heart block (CHB) from the 30th to the 37th week of gestation using the multichannel SQUID system (Hitachi, Japan). M-mode ultrasonography and direct fetal electrocardiography using needle electrodes revealed fetal CHB. We identified independen...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000053878

    authors: Hosono T,Chiba Y,Shinto M,Miyashita S,Muramaki K,Kandori A,Tsukada K

    更新日期:2001-01-01 00:00:00

  • Associated malformations and chromosomal defects in congenital diaphragmatic hernia.

    abstract::In order to determine the frequency of associated malformations and chromosomal defects in patients with congenital diaphragmatic hernia (CDH) our experiences with CDH during the last 8 years (1985-1993) were reviewed. During the study period, 33 fetuses (prenatal group) with CDH were examined at our level III ultraso...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000264193

    authors: Bollmann R,Kalache K,Mau H,Chaoui R,Tennstedt C

    更新日期:1995-01-01 00:00:00

  • Prognostic value of change in amniotic fluid color during labor.

    abstract:OBJECTIVE:Evidence of meconium-stained amniotic fluid (AF) during labor suggests implementation of close monitoring of fetal well-being. We have investigated whether the presence of meconium in the AF on admission for labor is as important a predictor of neonatal outcome as a change in AF color during labor. METHODS:A...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000081359

    authors: Locatelli A,Regalia AL,Patregnani C,Ratti M,Toso L,Ghidini A

    更新日期:2005-01-01 00:00:00

  • Mathematical models for fetal growth: application for biparietal diameter measurement.

    abstract::Evaluation of the adequacy of fetal growth by measurements of fetal size required theoretical formulae for the assessment of present size from previous measurements. The various models presented in the literature assume the same mathematical formula for the whole pregnancy. In this study, a model of different polynomi...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000263955

    authors: Nitzan M,Tadmor OP,Skomorowski Y,Rabinowitz R,Diamant Y

    更新日期:1994-09-01 00:00:00

  • Criteria for screening and diagnosis of gestational diabetes mellitus in the first trimester of pregnancy.

    abstract:OBJECTIVE:To propose new cutoffs in plasma glucose levels in screening and diagnosis of gestational diabetes mellitus (GDM) in the first trimester of pregnancy. METHODS:A 50-gram oral glucose challenge test (GCT) was performed in 1,716 singleton pregnancies at 6-14 weeks' gestation. In those with a positive GCT, a 100...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000324684

    authors: Plasencia W,Garcia R,Pereira S,Akolekar R,Nicolaides KH

    更新日期:2011-01-01 00:00:00

  • Prenatal diagnosis of oral cyst caused by foregut duplication.

    abstract::Prenatal diagnosis of oral cystic lesions is rare but is reported more frequently. The diagnosis of sublingual cyst is important because of the potential for airway obstruction. A rare case of a foregut duplication cyst associated with unilateral sclerocorneal microphthalmia is reported. The differential diagnosis and...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000235883

    authors: Aviram R,Yaffe D,Kidron D,Tepper R,Regev R

    更新日期:2009-01-01 00:00:00

  • Rare case of exomphalos complicated with umbilical cord teratoma in a fetus with trisomy 13.

    abstract::An exomphalos containing unusual solid and cystic mass was diagnosed during a routine ultrasound examination in the 17th week of gestation. Further investigations were planned but the pregnancy was terminated. The fetopathological examination revealed an umbilical cord teratoma. Although this entity is very rare it sh...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000088045

    authors: Hargitai B,Csabai L,Bán Z,Hetényi I,Szucs I,Varga S,Papp Z

    更新日期:2005-11-01 00:00:00

  • Prenatal diagnosis for Schmid metaphyseal chondrodysplasia in twins.

    abstract::We report prenatal diagnostic studies for metaphyseal chondrodysplasia of the Schmid type. Identification of a specific COL10A1 gene mutation in an affected father allowed prenatal diagnosis by chorionic villus sampling in a twin pregnancy. Neither of the nonidentical twins received the abnormal COL10A1 gene from thei...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000020831

    authors: Milunsky J,Maher T,Lebo R,Milunsky A

    更新日期:1998-05-01 00:00:00

  • A stillborn fetus with amniotic band syndrome and elevated levels of alpha-fetoprotein plus beta-human chorionic gonadotropin: a case report.

    abstract::Amniotic band syndrome is an uncommon, congenital fetal abnormality with multiple disfiguring and disabling manifestations. A wide spectrum of clinical deformities are encountered and range from simple ring constrictions to major craniofacial and visceral defects. We report a case of constriction amniotic bands involv...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000142139

    authors: Sifakis S,Mantas N,Konstantinidou A,Koukoura O,Avgoustinakis E,Koumantakis E

    更新日期:2008-01-01 00:00:00

  • Role of ultrasonography in pregnancies with marker chromosome aneuploidy.

    abstract::The objective of this report was to evaluate the effect of ultrasonographic (US) findings on pregnancy management in patients with marker chromosome (MC) aneuploidy ascertained through prenatal diagnosis. From 1989 through June 1993, 15,522 prenatal diagnostic procedures were performed for accepted indications. Charts...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000264230

    authors: Hume RF Jr,Drugan A,Ebrahim SA,Johnson MP,Isada NB,Reichler A,Evans MI

    更新日期:1995-05-01 00:00:00

  • Management of a case of twin-to-twin transfusion syndrome by a combined surgical approach.

    abstract:OBJECTIVE:The management of a case of severe twin-to-twin transfusion syndrome at 24 weeks of gestation is presented, using a combined surgical and medical approach. METHODS:Operative fetoscopy was used to coagulate placental vessels crossing the intertwin membranes. Repeated intrauterine transfusions were used to cor...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000020809

    authors: Van Peborgh P,Pelletier G,Suarez B,Ville Y

    更新日期:1998-03-01 00:00:00

  • Direct fetal intravenous immunoglobulin infusion as an adjunct to intrauterine fetal blood transfusion in rhesus-allommunized pregnancies: a pilot study.

    abstract:OBJECTIVES:To study the usefulness of direct fetal intravenous immunoglobulin (IVIG) infusion along with intrauterine transfusion (IUT) in the management of severe fetal anemia in rhesus (Rh) alloimmunized pregnancies. METHODS:Thirty-four consecutive Rh-isoimmunized pregnant women who required serial IUTs received eit...

    journal_title:Fetal diagnosis and therapy

    pub_type: 临床试验,杂志文章

    doi:10.1159/000353236

    authors: Deka D,Sharma KA,Dadhwal V,Singh A,Kumar G,Vanamail P

    更新日期:2013-01-01 00:00:00

  • Course of maternal serum magnesium levels in low-risk gestations and in preterm labor and delivery.

    abstract:OBJECTIVES:To describe the course of total and ionized magnesium and total calcium levels in maternal serum during low-risk pregnancies and to compare women who developed preterm labor and delivery with those who delivered at term. METHODS:209 women with low-risk pregnancies were enrolled in a prospective trial before...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000020952

    authors: Arikan GM,Panzitt T,Gücer F,Scholz HS,Reinisch S,Haas J,Weiss PA

    更新日期:1999-11-01 00:00:00

  • Pulmonary Vein Flow Impedance: An Early Predictor of Cardiac Dysfunction in Intrauterine Growth Restriction.

    abstract:INTRODUCTION:In intrauterine growth restriction (IUGR), increased uteroplacental vascular impedance contributes to preferential flow to left ventricle (LV), with consequent alteration of its compliance and increased left atrial (LA) pressure. Pulmonary vein pulsatility index (PVPI) reflects the increased impedance to L...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000488281

    authors: Bravo-Valenzuela NJM,Zielinsky P,Zurita-Peralta J,Nicoloso LH,Piccoli A Jr,Ferreira Van der Sand L,Miranda Sulis N,Carvalho Ritter C

    更新日期:2019-01-01 00:00:00

  • Transabdominal amnioinfusion in preterm pregnancies complicated by fetal growth restriction, oligohydramnios and umbilical cord compression.

    abstract::Fetal growth restriction with oligohydramnios occurring in the preterm gestation is associated with significant fetal morbidity and mortality. We investigated the possibility that transabdominal amnioinfusion might relieve acute cord compression and allow prolongation of gestation long enough to administer corticoster...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000264266

    authors: Sarno AP,Polzin WJ,Feinstein SJ,Maslow A

    更新日期:1995-11-01 00:00:00

  • Maturity of the myenteric plexus is decreased in the gastroschisis rat model.

    abstract:BACKGROUND:Amniotic fluid (AF) and its components, such as fetal urine and meconium, may lead to intestinal alterations in gastroschisis, which cause immaturity of the myenteric plexus and consequent intestinal hypomotility and malabsorption. In this study we identified morphological and histological alterations of the...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000109228

    authors: França WM,Langone F,de la Hoz CL,Gonçalves A,Bittencourt D,Pereira LV,Sbragia L

    更新日期:2008-01-01 00:00:00

  • A study to determine if human umbilical cord hematopoietic stem cells can survive in baboon extra-embryonic celomic fluid: a prerequisite for determining the feasibility of in-utero stem cell xeno-transplantation via celocentesis.

    abstract:OBJECTIVES:To determine if: (1) human umbilical cord stem cells could survive for 20 h in extra-embryonic celomic fluid obtained at 40 days of development from baboon pregnancies by ultrasound-guided celocentesis and, (2) human hematopoietic stem cell survival could be enhanced by adding increasing concentrations of he...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000097112

    authors: Santolaya-Forgas J,Galan I,Deleon-Luis J,Wolf R

    更新日期:2007-01-01 00:00:00

  • Uterine myomectomy in pregnant women.

    abstract:OBJECTIVE:To determine whether myomectomy during pregnancy in selected patients improves outcome. METHODS:Retrospective analysis of 18 patients who underwent myomectomy between the 6th and 24th week of gestational age. Surgical management of tumors was required on the basis of the characteristics of the myomas and sym...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000053893

    authors: De Carolis S,Fatigante G,Ferrazzani S,Trivellini C,De Santis L,Mancuso S,Caruso A

    更新日期:2001-03-01 00:00:00

  • Hemimegalencephaly: 2D, 3D Ultrasound and MRI Correlation.

    abstract:BACKGROUND:Hemimegalencephaly (HMC) is a disorder associated with enlarged and dysplastic hamartomatous overgrowth of all or part of the one cerebral hemisphere that can be isolated or associated with other syndromes. In the normal development of the brain it is important to bear in mind that there are two main process...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000322012

    authors: Romero XC,Molina FS,Pastor E,Amaya F

    更新日期:2011-01-01 00:00:00

  • Prenatal sonographic diagnosis of fetal adrenal gland hemorrhage.

    abstract:BACKGROUND:In newborn the finding of adrenal gland hemorrhage is not uncommon. Only few cases of prenatal diagnosis of fetal adrenal bleeding by sonography have been reported. CASE:In a 28-year-old nulliparous pregnant woman, routine sonography performed in 35 + 2 weeks of gestational age showed a cystic mass on the u...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000264316

    authors: Vollersen E,Hof M,Gembruch U

    更新日期:1996-07-01 00:00:00

  • Perinatal outcome of monochorionic twins with selective intrauterine growth restriction and different types of umbilical artery Doppler under expectant management.

    abstract:OBJECTIVES:To evaluate the prognosis of monochorionic twins with selective intrauterine growth restriction (sIUGR), classified according to the type of umbilical artery Doppler, under expectant management. METHODS:The outcome of 81 cases with isolated sIUGR was evaluated according to a classification based on umbilica...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000253880

    authors: Ishii K,Murakoshi T,Takahashi Y,Shinno T,Matsushita M,Naruse H,Torii Y,Sumie M,Nakata M

    更新日期:2009-01-01 00:00:00

  • Maternal Anxiety and the Second-Trimester Prenatal Screening: A Prospective Cohort Study.

    abstract:OBJECTIVE:Assessing the effects of maternal anxiety on the markers and results of quadruple screening and on maternal anxiety after receiving positive results. METHODS:This prospective cohort study evaluated 1,595 pregnant women referred for prenatal visits. Maternal state/trait anxiety levels were measured, then quad...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000381640

    authors: Mousavi S,Hantoushzadeh S,Sheikh M,Shariat M

    更新日期:2015-01-01 00:00:00

  • Perinatal outcome of conservative management versus fetal intervention for twin reversed arterial perfusion sequence with a small acardiac twin.

    abstract:OBJECTIVE:To examine the outcomes of patients with twin reversed arterial perfusion (TRAP) sequence in which the acardiac twin was

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000295176

    authors: Jelin E,Hirose S,Rand L,Curran P,Feldstein V,Guevara-Gallardo S,Jelin A,Gonzales K,Goldstein R,Lee H

    更新日期:2010-01-01 00:00:00

  • Fetal cardiovascular physiology and therapy.

    abstract::The ability to diagnose fetal cardiovascular malformations prenatally has been established during the past 14 years. This has naturally led to an increased interest in the possibility of providing timely therapy in the neonatal period and has raised the prospects for prenatal intervention. Before medical, catheter, an...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章,评审

    doi:10.1159/000263663

    authors: Kleinman CS,Copel JA

    更新日期:1992-01-01 00:00:00

  • Amnioreduction: how much to drain?

    abstract:OBJECTIVES:To assess the relationship between the volume of amniotic fluid removed and the change in amniotic fluid index (AFI) and calculate an equation describing this association. MATERIALS AND METHODS:A retrospective analysis of 19 amnioreduction procedures performed in our unit. Multiple regression analysis was u...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000020939

    authors: Abdel-Fattah SA,Carroll SG,Kyle PM,Soothill PW

    更新日期:1999-09-01 00:00:00

  • Validation of an Enhanced Version of a Single-Nucleotide Polymorphism-Based Noninvasive Prenatal Test for Detection of Fetal Aneuploidies.

    abstract:OBJECTIVE:To validate an updated version (Version 2) of a single-nucleotide polymorphism (SNP)-based noninvasive prenatal test (NIPT) and to determine the likelihood of success when testing for fetal aneuploidies following a redraw. METHODS:Version 2 was analytically validated using 587 plasma samples with known genot...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000442931

    authors: Ryan A,Hunkapiller N,Banjevic M,Vankayalapati N,Fong N,Jinnett KN,Demko Z,Zimmermann B,Sigurjonsson S,Gross SJ,Hill M

    更新日期:2016-01-01 00:00:00

  • Detection of skin over cysts with Spina bifida may be useful not only for preventing neurological damage during labor but also for predicting fetal prognosis.

    abstract::Spina bifida is one of the most common open neural tube defects. There are two common types of spina bifida cystica, myelomeningocele and meningocele. Special attention to the thickness of the cystic sac (presence of intact skin and subcutaneous tissue) on magnetic resonance imaging is advantageous for determination o...

    journal_title:Fetal diagnosis and therapy

    pub_type: 杂志文章

    doi:10.1159/000020996

    authors: Oya N,Suzuki Y,Tanemura M,Kojima K,Kajiura S,Murakami I,Yamashita N,Suzumori K

    更新日期:2000-05-01 00:00:00