An ethically justified decision-making pathway for the management of pregnancies complicated by twin-to-twin transfusion syndrome.

abstract：OBJECTIVE:Assessing the effects of maternal anxiety on the markers and results of quadruple screening and on maternal anxiety after receiving positive results. METHODS:This prospective cohort study evaluated 1,595 pregnant women referred for prenatal visits. Maternal state/trait anxiety levels were measured, then quad...

journal_title：Fetal diagnosis and therapy

authors： Mousavi S,Hantoushzadeh S,Sheikh M,Shariat M

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To validate an updated version (Version 2) of a single-nucleotide polymorphism (SNP)-based noninvasive prenatal test (NIPT) and to determine the likelihood of success when testing for fetal aneuploidies following a redraw. METHODS:Version 2 was analytically validated using 587 plasma samples with known genot...

journal_title：Fetal diagnosis and therapy

authors： Ryan A,Hunkapiller N,Banjevic M,Vankayalapati N,Fong N,Jinnett KN,Demko Z,Zimmermann B,Sigurjonsson S,Gross SJ,Hill M

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:The aim of this study was to describe the association between fetal echogenic bowel (FEB) diagnosed during the second trimester and adverse perinatal outcomes in an Australian antenatal population. METHODS:A retrospective analysis of ultrasound scans was performed between March 1, 2004 and March 1, 2009 a...

journal_title：Fetal diagnosis and therapy

authors： Ameratunga DM,Said JM,Reidy K,Palma-Dias R

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Fetal gene replacement is a novel, potential therapy for monogenic disorders which are diagnosed prenatally. The purpose of this study was to develop in vitro, respiratory-epithelium targeted, lentiviral (LV)-mediated gene transfer in fetal rabbit tracheas. METHODS:Via triple plasmid transfection, vesicular ...

journal_title：Fetal diagnosis and therapy

authors： Huang L,Reebye SC,Yeung AY,Jia WW,Skarsgard ED

更新日期：2006-01-01 00:00:00

abstract：:In order to determine the frequency of associated malformations and chromosomal defects in patients with congenital diaphragmatic hernia (CDH) our experiences with CDH during the last 8 years (1985-1993) were reviewed. During the study period, 33 fetuses (prenatal group) with CDH were examined at our level III ultraso...

journal_title：Fetal diagnosis and therapy

authors： Bollmann R,Kalache K,Mau H,Chaoui R,Tennstedt C

更新日期：1995-01-01 00:00:00

abstract：:It has long been appreciated that the measurement of biochemical parameters for prenatal screening for neural tube defects, and later aneuploidy, is not as simple as measuring hemoglobin or hematocrit. Early in the game, it was recognized that there are gestational age curves, and that since alpha-fetoprotein (AFP), f...

journal_title：Fetal diagnosis and therapy

authors： Brooks K,Chik L,O'Brien JE,Ayoub M,Johnson MP,Evans MI

更新日期：1999-01-01 00:00:00

abstract：:Bronchopulmonary sequestration with associated nonimmune hydrops has been previously reported with generally poor prognosis for the neonate. We report a case of bronchopulmonary sequestration and associated pleural effusion successfully managed with a transthoracic catheter placement. The embryology and clinical patho...

journal_title：Fetal diagnosis and therapy

authors： Slotnick RN,McGahan J,Milio L,Schwartz M,Ablin D

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:To improve neonatal outcomes in pregnancies at heightened risk for early-onset neonatal sepsis (EONS), there is a need to identify fetuses that benefit from expectant management as opposed to early delivery. Detectable haptoglobin and haptoglobin-related protein (Hp&HpRP switch-on status) in cord blood has b...

journal_title：Fetal diagnosis and therapy

authors： Archabald KL,Buhimschi IA,Bahtiyar MO,Dulay AT,Abdel-Razeq SS,Pettker CM,Lipkind HS,Hardy JT,McCarthy ME,Zhao G,Bhandari V,Buhimschi CS

更新日期：2017-01-01 00:00:00

abstract：:Thoraco-amniotic shunting was performed in 51 singleton pregnancies for decompression and chronic drainage of fetal pleural effusions (n = 47), pericardial effusion (n = 1), or pulmonary cysts (n = 3). Five fetuses had chromosomal defects and in 4 the parents elected termination of pregnancy. All 18 non-hydropic fetus...

journal_title：Fetal diagnosis and therapy

authors： Nicolaides KH,Azar GB

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:This report wants to focus on the risk of severe prematurity in patients with the hypermobility type of the Ehlers-Danlos syndrome (EDS), a heritable disorder of connective tissue. Although various obstetrical complications have been reported in patients with EDS, most reports specifically comment on the sev...

journal_title：Fetal diagnosis and therapy

authors： De Vos M,Nuytinck L,Verellen C,De Paepe A

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the failure rate and performance of cell-free DNA (cfDNA) testing, mainly in terms of detection rates for trisomy 21, performed by 2 laboratories using different analytical methods. METHODS:cfDNA testing was performed on 2,870 pregnancies with the HarmonyTM Prenatal Test using the targeted digit...

journal_title：Fetal diagnosis and therapy

authors： Bevilacqua E,Jani JC,Letourneau A,Duiella SF,Kleinfinger P,Lohmann L,Resta S,Cos Sanchez T,Fils JF,Mirra M,Benachi A,Costa JM

更新日期：2019-01-01 00:00:00

abstract：:Rapid fluorescence in situ hybridization (FISH) performed on 1,788 amniocenteses, using Aneuvision (Vysis) probes for chromosomes 13, 18, 21, X, and Y, over several years, yielded 115 cases with percentages of aneuploidy between 4 and 100%. All cases above 60% were confirmed to be positive by chromosome analysis. Fift...

journal_title：Fetal diagnosis and therapy

authors： Wyandt HE,Tonk VS,Huang XL,Evans AT,Milunsky JM,Milunsky A

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:To determine whether myomectomy during pregnancy in selected patients improves outcome. METHODS:Retrospective analysis of 18 patients who underwent myomectomy between the 6th and 24th week of gestational age. Surgical management of tumors was required on the basis of the characteristics of the myomas and sym...

journal_title：Fetal diagnosis and therapy

authors： De Carolis S,Fatigante G,Ferrazzani S,Trivellini C,De Santis L,Mancuso S,Caruso A

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:Myelomeningocele is a neural tube defect resulting in an exposed spinal cord, which leads to irreversible neurologic damage at birth. We proposed development of a fetal rabbit model of myelomeningocele to study in utero spinal cord injury and repair strategies. METHODS:New Zealand white rabbits (n = 10) at 2...

journal_title：Fetal diagnosis and therapy

authors： Housley HT,Graf JL,Lipshultz GS,Calvano CJ,Harrison MR,Farmer DL,Jennings RW

更新日期：2000-09-01 00:00:00

abstract：:Intrauterine growth restriction (IUGR) is an adverse pregnancy outcome associated with significant perinatal and pediatric morbidity and mortality, and an increased risk of chronic disease later in adult life. While a number of maternal, fetal and environmental factors are known causes of IUGR, the majority of IUGR ca...

journal_title：Fetal diagnosis and therapy

authors： Murthi P,Kalionis B,Rajaraman G,Keogh RJ,Da Silva Costa F

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Evidence of meconium-stained amniotic fluid (AF) during labor suggests implementation of close monitoring of fetal well-being. We have investigated whether the presence of meconium in the AF on admission for labor is as important a predictor of neonatal outcome as a change in AF color during labor. METHODS:A...

journal_title：Fetal diagnosis and therapy

authors： Locatelli A,Regalia AL,Patregnani C,Ratti M,Toso L,Ghidini A

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To describe a technique for the visualization and measurement of cerebral aqueduct diameter through a 2D sagittal median plane, and to report its aspect and measurement in fetuses with aqueductal stenosis (AS). METHODS:This was a cross-sectional study of 207 morphologically normal fetuses in low-risk pregnan...

journal_title：Fetal diagnosis and therapy

authors： Viñals F,Ruiz P,Quiroz G,Guerra FA,Correa F,Martínez D,Puerto B

更新日期：2017-01-01 00:00:00

abstract：:Spontaneous preterm birth has enormous consequences for newborns, children, and families. Intra-amniotic inflammation (IAI) is the leading cause of spontaneous preterm delivery, mainly at earlier gestational ages. Amniocentesis is the only method used to identify IAI in clinical practice. Although it is an invasive pr...

journal_title：Fetal diagnosis and therapy

authors： Cobo T,Kacerovsky M,Jacobsson B

更新日期：2018-01-01 00:00:00

abstract：:A case is presented in which ultrasonographic examination led to the prenatal detection of a ring 13 chromosome in a fetus. At 18 weeks' gestation, the fetus presented with holoprosencephaly, an abnormal configuration of the lower extremities, and an atrial septal defect. Although the amount of amniotic fluid was norm...

journal_title：Fetal diagnosis and therapy

authors： Santolaya J,McCorquodale MM,Torres W,Meyer WJ,Gauthier D,Lemery D

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Chronically compromised uterine perfusion may lead to placental insufficiency and subsequent intrauterine growth restriction (IUGR). Various therapeutic approaches (e.g. vasodilators, low-dose aspirin, intravenous glucose infusion, and hemodilution) are often of limited efficacy. Local anesthetics have been ...

journal_title：Fetal diagnosis and therapy

authors： Strümper D,Louwen F,Durieux ME,Gramke HF,Stuessel J,Marcus-Soekarman D,Van Aken H,Marcus MA

更新日期：2005-05-01 00:00:00

abstract：:Since its inception in 1995, the mission of the Center for Fetal Diagnosis and Treatment at the Children's Hospital of Philadelphia (CHOP) has been to provide comprehensive, multidisciplinary expertise in all facets of prenatal diagnosis, reproductive genetics, and prenatal, perinatal, and postnatal treatment for abno...

journal_title：Fetal diagnosis and therapy

authors： Hedrick HL,Flake AW,Crombleholme TM,Howell LJ,Johnson MP,Wilson RD,Adzick NS

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVES:To examine the assumption that amniotic fluid alpha-fetoprotein (AFAFP) levels are different in female and male twin fetuses. DESIGN:Amniotic fluid levels of AFP in pregnancies with female and male fetuses in gender-concordant and gender-discordant twins were compared. A t test of p < 0.05 was considered si...

journal_title：Fetal diagnosis and therapy

authors： Sharony R,Drugan A,Amiel A,Grinshpun-Cohen J,Markov S,Fejgin MD

更新日期：2003-07-01 00:00:00

abstract：:Here we report a case of conjoined twins that were diagnosed antenatally by routine two-dimensional transvaginal ultrasound examination at as early as the 9th week of gestational age. The fetuses were of the thoraco-omphalopagus type and were sharing the liver, as confirmed by color Doppler. There was a reversed flow ...

journal_title：Fetal diagnosis and therapy

authors： Basgül A,Kavak ZN,Sezen D,Basgul A,Gokaslan H

更新日期：2006-01-01 00:00:00

abstract：:We report a case of fetal goitrous hypothyroidism followed by neonatal transient hyperthyroidism. A fetal goiter (26 x 38 mm) was detected by ultrasound and magnetic resonance imaging at 29 weeks of gestation. Hypothyroidism was confirmed by cordocentesis, which revealed an elevated TSH (255 microIU/ml) and a low free...

journal_title：Fetal diagnosis and therapy

authors： Matsumoto T,Miyakoshi K,Kasai K,Ishimoto H,Tanaka M,Ikeda K,Yoshimura Y

更新日期：2003-11-01 00:00:00

abstract：INTRODUCTION:The aim of this study is to evaluate the incidence and causes of intentional fetal and neonatal demise in twin-twin transfusion syndrome (TTTS). MATERIAL AND METHODS:All TTTS pregnancies managed at our centre between 2000 and 2014 were included. We evaluated incidence and causes of intentional fetal/neona...

journal_title：Fetal diagnosis and therapy

authors： Spruijt MS,Tameeris E,Zhao DP,Middeldorp JM,Haak MC,Oepkes D,Lopriore E

更新日期：2018-01-01 00:00:00

abstract：:The umbilical artery, aorta, and middle cerebral artery pulsatility indices were investigated by pulsed Doppler ultrasound in 73 fetuses at 18-37 weeks of gestation, before and after fetal blood sampling performed either at the placental cord insertion (n = 46) or at the intrahepatic vein (n = 27). At the end of the p...

journal_title：Fetal diagnosis and therapy

authors： Zoppini C,Brioschi D,Tassis B,Zuliani G,Kustermann A,Nicolini U

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of smoking and number of previous births on maternal serum levels of alpha-fetoprotein and free beta-subunit of human chorionic gonadotropin (free beta-hCG). METHODS:The study included 3,252 completed unaffected singleton pregnancies that proceeded beyond 37 weeks' gestation and result...

journal_title：Fetal diagnosis and therapy

authors： Tislarić D,Brajenović-Milić B,Ristić S,Latin V,Zuvić-Butorac M,Bacić J,Petek M,Kapović M

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:To determine if: (1) human umbilical cord stem cells could survive for 20 h in extra-embryonic celomic fluid obtained at 40 days of development from baboon pregnancies by ultrasound-guided celocentesis and, (2) human hematopoietic stem cell survival could be enhanced by adding increasing concentrations of he...

journal_title：Fetal diagnosis and therapy

authors： Santolaya-Forgas J,Galan I,Deleon-Luis J,Wolf R

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:We reviewed women with previable spontaneous premature rupture of membranes (sPPROM) in whom an amniopatch was performed and compared their pregnancy outcomes with a conservative management group. METHODS:Amniopatch, an amnioinfusion of autologous platelet concentrate followed by cryoprecipitate, was perform...

journal_title：Fetal diagnosis and therapy

authors： Kwak HM,Choi HJ,Cha HH,Yu HJ,Lee JH,Choi SJ,Oh SY,Roh CR,Kim JH

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To assess the sonographic visualization of the pericallosal arteries in normal fetuses at 11-13 weeks of gestation using 3D ultrasound. METHODS:We prospectively enrolled women with a singleton pregnancy undergoing ultrasound at 11-13 weeks of gestation. A 3D volume with high-definition power Doppler was acqu...

journal_title：Fetal diagnosis and therapy

authors： Conturso R,Contro E,Bellussi F,Youssef A,Pacella G,Martelli F,Rizzo N,Pilu G,Ghi T

更新日期：2015-01-01 00:00:00