A serological study of hepatitis C infection in plasmapheresis donors.

Abstract:

:An epidemic of parenterally transmitted non-A, non-B hepatitis (PT-NANBH) occurred in plasmapheresis donors in Guan County, Hebei Province, China, in 1985. PT-NANBH was diagnosed by epidemiological studies and serological exclusion of HAV, HBV, CMV and EBV infections. Recently, 163 sera samples of 108 patients with PT-NANBH and 65 sera samples of 49 cases with elevated alanine aminotransferase (ALT) levels collected during the epidemic were tested by anti-HCV EIA (Chiron C100). The positive rates of anti-HCV in these two groups were 89.8% (97/108) and 93.9% (46/49), averaging 90.8%. The figures increased with the course of illness and persistance of ALT elevation, i.e., 17.6% and 55.6% within 1 month, 88.9% and 87.5% at 6 months and 100% and 100% after 2 years. Five patients with PT-NANBH and 1 with elevated ALT levels were followed up for 3 to 4 years. We demonstrated that anti-HCV remained positive after the disease had resolved and ALT levels had normalized.

journal_name

Chin Med J (Engl)

journal_title

Chinese medical journal

authors

Meng ZD,Sun YD,Chen XR,Wang SY,Sun DG,Chen Z,Liu CB,Zhuang H,Xu ZY

keywords:

subject

Has Abstract

pub_date

1991-06-01 00:00:00

pages

494-7

issue

6

eissn

0366-6999

issn

2542-5641

journal_volume

104

pub_type

杂志文章
  • Paraquat induces selective dopaminergic nigrostriatal degeneration in aging C57BL/6 mice.

    abstract:BACKGROUND:Paraquat (PQ; 1, 1'-dimethyl-4, 4'-bipyridinium), a widely used herbicide that is structurally similar to the known dopaminergic neurotoxicant MPTP (1-methyl-1, 2, 3, 6-tetrahydropyridine), has been suggested as a potential etiologic factor for the development of Parkinson's disease (PD). Aging is an accepte...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Li X,Yin J,Cheng CM,Sun JL,Li Z,Wu YL

    更新日期:2005-08-20 00:00:00

  • Effects of antipsoriatic drugs on biosynthesis of platelet activating factor by human keratinocytes.

    abstract::Human keratinocytes in primary culture stimulated by Ca2+ ionophore A23187(Io) could synthesize and release a material which might aggregate aspirin-treated washed rabbit platelets and was identified as platelet activating factor (PAF) by four methods. Io stimulated the production of PAF by keratinocytes in a time- an...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu BJ,Zheng MR,Zhang SZ,Dai FP

    更新日期:1994-05-01 00:00:00

  • Safety and efficacy of first-line bevacizumab combined with taxane therapy in Chinese patients with HER2-negative locally recurrent or metastatic breast cancer: findings from the ATHENA study.

    abstract:BACKGROUND:Three randomised trials have demonstrated that combining bevacizumab with first-line chemotherapy significantly improves progression-free survival versus chemotherapy alone in HER2-negative locally recurrent/metastatic breast cancer (LR/mBC). However, data from Chinese populations are limited and possible di...

    journal_title:Chinese medical journal

    pub_type: 临床试验,杂志文章

    doi:

    authors: Xu BH,Jiang ZF,Shen ZZ,Guan ZZ,Chen ZD,Cheng Y,Zheng H,Jiang J,Wang XJ,Tong ZS,Qin SK,Luo Y,Yao M,Wang LW,He J

    更新日期:2012-03-01 00:00:00

  • Clinicopathological characteristics and prognostic factors of intrahepatic biliary cystadenocarcinoma.

    abstract:BACKGROUND:Surgical resection is generally considered the main curative treatment for intrahepatic biliary cystadenocarcinoma (IBCA) or suspected IBCAs, but controversy exists regarding the prognosis for IBCAs. This study aimed to describe the clinicopathological characteristics of IBCA and identify prognostic factors ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.156108

    authors: Xu MY,Shi XJ,Wan T,Liang YR,Wang HG,Zhang WZ,He L,Chen MY,Lyu SC,Zhang WW,Li HX

    更新日期:2015-05-05 00:00:00

  • Immunologic investigation of Chinese hemophiliacs with and without human immunodeficiency virus infection.

    abstract::Cellular and humoral immune functions in Chinese hemophiliacs with and without human immunodeficiency virus (HIV) infection were compared with those of healthy controls. There was a significant increase in peripheral T8 cells and a significant decrease of peripheral T4 cells as well as the T4/T8 ratio in 3 hemophiliac...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Tang DJ,Pang XG

    更新日期:1991-10-01 00:00:00

  • Newly detected atrial fibrillation is associated with cortex-involved ischemic stroke.

    abstract:BACKGROUND:Both cortical and cortical-subcortical (cortex-involved) lesions are typically associated with embolic stroke, of which atrial fibrillation (AF) is the common cause. The aim of this study was to find out the associations between cortex-involved stroke, vascular risk factors, and the subtypes (discovery time ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000390

    authors: Li SY,Yang XM,Zhao XQ,Liu LP,Wang YL,Jiang Y,Wang YJ

    更新日期:2019-09-05 00:00:00

  • Variation analysis of the severe acute respiratory syndrome coronavirus putative non-structural protein 2 gene and construction of three-dimensional model.

    abstract:BACKGROUND:The rapid transmission and high mortality rate made severe acute respiratory syndrome (SARS) a global threat for which no efficacious therapy is available now. Without sufficient knowledge about the SARS coronavirus (SARS-CoV), it is impossible to define the candidate for the anti-SARS targets. The putative ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Lu JH,Zhang DM,Wang GL,Guo ZM,Zhang CH,Tan BY,Ouyang LP,Lin L,Liu YM,Chen WQ,Ling WH,Yu XB,Zhong NS

    更新日期:2005-05-05 00:00:00

  • Nutrient Intakes of Pregnant Women and their Associated Factors in Eight Cities of China: A Cross-sectional Study.

    abstract:BACKGROUND:During the last 3 decades, China has dramatic changes of the dietary pattern among its citizens, particularly in urban cities. This study aimed to determine the nutrient intake status and factors associated with nutrient intakes of urban Chinese pregnant women now-a-day. METHODS:The multistage stratified ra...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.159354

    authors: Liu FL,Zhang YM,Parés GV,Reidy KC,Zhao WZ,Zhao A,Chen C,Ning CY,Zheng YD,Wang PY

    更新日期:2015-07-05 00:00:00

  • Epigallocatechin-3-gallate Modulates MicroRNA Expression Profiles in Human Nasopharyngeal Carcinoma CNE2 Cells.

    abstract:BACKGROUND:Epigallocatechin-3-gallate (EGCG) has exhibited antitumor properties in several types of cancers, including nasopharyngeal carcinoma (NPC), but the molecular mechanisms underlying this function remain incompletely understood. The aim of the present study was to characterize the global impact of EGCG on the e...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.196586

    authors: Li BB,Huang GL,Li HH,Kong X,He ZW

    更新日期:2017-01-05 00:00:00

  • Aldosterone biosynthesis in extraadrenal tissues.

    abstract:OBJECTIVE:To determine whether extraadrenal tissues synthesize aldosterone in addition to vascular tissue and brain. METHODS:Ex vivo kidney perfusion was performed in normal Wistar rats, ACEI pretreated and adrenalectomized rats prior to the perfusion experiment. After equilibration for 30 minutes, 120 ml of perfusate...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wu P,Liang X,Dai Y,Liu H,Zang Y,Guo Z,Zhang R,Lai W,Zhang Y,Liu Y

    更新日期:1999-05-01 00:00:00

  • Transposition of iliac periosteum with vascular pedicle and compression screw fixation for transcervical fracture of femur. Experimental research and clinical application.

    abstract::The vascular pedicled periosteum was used in 11 cases in our hospital for the treatment of femoral neck fracture with good result. The follow-up period ranged from 2 to 6 years, with an average of 4 years. Animal experiment was made to elucidate the repairing process. It demonstrated that the pedicled periosteum playe...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Zhu SX,Shen YN,Lu SB,Zhang BX,Wang JF

    更新日期:1989-01-01 00:00:00

  • Novel mitochondrial 16S rRNA mutation, 3200T-->C, associated with adult-onset type 2 diabetes.

    abstract:OBJECTIVE:To investigate the role of a potential diabetes-related mitochondrial region, which includes two previously reported mutations, 3243A-->G and 3316G-->A, in Chinese patients with adult-onset type 2 diabetes. METHODS:A total of 277 patients and 241 normal subjects were recruited for the study. Mitochondrial nt...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Yang T,Lam CW,Tsang MW,Tong SF,Kam GY,Chan LY,Poon PM,Wu X,Pang CP

    更新日期:2002-05-01 00:00:00

  • Clinical results of combined palliative procedures for cyanotic congenital heart defects with intractable hypoplasia of pulmonary arteries.

    abstract:BACKGROUND:Congenital heart defects with intractable hypoplasia of the pulmonary arteries without intercourse or with intercourse stenosis is unsuitable for surgical correction or regular palliative procedures. We reported our experience with combined palliative procedures for congenital heart defects with intractable ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Fan XM,Zhu YB,Su JW,Zhang J,Li ZQ,Xu YQ,Li XF,Liu YL

    更新日期:2013-01-01 00:00:00

  • Enhanced invasion in vitro and the distribution patterns in vivo of CD133+ glioma stem cells.

    abstract:BACKGROUND:Recent studies have suggested that cancer stem cells cause tumor recurrence based on their resistance to radiotherapy and chemotherapy. Although the highly invasive nature of glioblastoma cells is also implicated in the failure of current therapies, it is not clear whether cancer stem cells are involved in i...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Yu SP,Yang XJ,Zhang B,Ming HL,Chen C,Ren BC,Liu ZF,Liu B

    更新日期:2011-09-01 00:00:00

  • Endothelial progenitor cell down-regulation in a mouse model of Kawasaki disease.

    abstract:BACKGROUND:Cardiovascular complications of Kawasaki disease (KD) are a common cause of heart disease in pediatric populations. Previous studies have suggested a role for endothelial progenitor cells (EPCs) in coronary artery lesions associated with KD. However, long-term observations of EPCs during the natural progress...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Liu JF,Du ZD,Chen Z,Lu DX,Li L,Guan YQ,Wan SG

    更新日期:2012-02-01 00:00:00

  • An analysis of prognostic factors in cirrhosis.

    abstract::To develop a more comprehensive index for predicting the prognous of liver cirrhosis. 300 consecutive patients with cirrhosis were studied in terms of survival from 1975 to 1986. Median follow-up period was 5.3 years. A multivariable survival analysis (Cox's regression model) using clinical biochemical data obtained a...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang JY,Liu HY,Zhu WN,Han JQ,Dong CY,Shi YJ,Cai HJ,Cao JM,Yi QL

    更新日期:1989-04-01 00:00:00

  • Hydrogen sulfide and nervous system regulation.

    abstract:OBJECTIVE:This review discusses the current status and progress in studies on the roles of hydrogen sulfide (H(2)S) in regulation of neurotoxicity, neuroprotection, and neuromodulator, as well as its therapeutic potential for neurodegenerative disorders. DATA SOURCES:The data used in this review were mainly from Medli...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Zhou CF,Tang XQ

    更新日期:2011-11-01 00:00:00

  • Pretreatment with repeated electroacupuncture attenuates transient focal cerebral ischemic injury in rats.

    abstract:OBJECTIVE:To investigate whether pretreatment with repeated electroacupuncture (EA) at the Baihui acupoint could induce ischemic tolerance against transient focal cerebral ischemic injury in rats. METHODS:Thirty male Sprague-Dawley (SD) rats were randomly divided into 3 groups (n=10 for each): the control group consis...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Xiong L,Lu Z,Hou L,Zheng H,Zhu Z,Wang Q,Chen S

    更新日期:2003-01-01 00:00:00

  • Meta-analysis of randomized trials comparing the effectiveness of on-pump and off-pump coronary artery bypass.

    abstract:BACKGROUND:The growing enthusiasm for coronary artery bypass grafting (CABG) without cardiopulmonary bypass (CPB) is emerging, but the role of off-pump coronary artery bypass (OPCAB) in clinical practice remains controversial. The purpose of this study was to assess differences in the incidences of stroke, atrial fibri...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,meta分析

    doi:

    authors: Chen YB,Shu J,Yang WT,Shi L,Guo XF,Wang FG,Qian YY

    更新日期:2012-01-01 00:00:00

  • Murine calcium-activated chloride channel family member 3 induces asthmatic airway inflammation independently of allergen exposure.

    abstract:BACKGROUND:Expression of murine calcium-activated chloride channel family member 3 (mCLCA3) has been reported to be increased in the airway epithelium of asthmatic mice challenged with ovalbumin (OVA). However, its role in asthmatic airway inflammation under no OVA exposure has not yet been clarified. METHODS:mCLCA3 p...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Mei L,He L,Wu SS,Zhang B,Xu YJ,Zhang ZX,Zhao JP,Zhang HL

    更新日期:2013-01-01 00:00:00

  • Randomized trial on the application of biofragmentable anastomosis ring in intestinal anastomosis.

    abstract:BACKGROUND:The biofragmentable anastomosis ring (BAR) is a simple alternative device to create intestinal anastomosis. Our study was designed to evaluate the clinical value of BAR in intestinal anastomosis. METHODS:A total of 167 patients performed intestinal anastomosis from January 2002 to February 2006 were randomi...

    journal_title:Chinese medical journal

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Chen S,Yang B,He JH,Zhang YC,Lai DM

    更新日期:2009-08-05 00:00:00

  • Age and menopausal status are important factors influencing the serum human epididymis secretory protein 4 level: a prospective cross-sectional study in healthy Chinese people.

    abstract:BACKGROUND:Human epididymis secretory protein 4 (HE4) is a new ovarian cancer biomarker. The factors influencing HE4 levels are not clear, and the reference data in China are limited. Here, we aim to evaluate the effects of menopause and age on HE4 levels and to provide a possible reference value for HE4 in healthy Chi...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000785

    authors: Cheng HY,Zeng L,Ye X,Ma RQ,Tang ZJ,Chu HL,Zhao YM,Zhu LR,Gao YN,Chang XH,Cui H

    更新日期:2020-06-05 00:00:00

  • Genetic heterogeneity for familial hypertrophic cardiomyopathy in Chinese: analysis of six Chinese kindreds.

    abstract:OBJECTIVE:Familial hypertrophic cardiomyopathy (FHCM) is a primary myocardial disease characterized by unexplained ventricular hypertrophy. The application of the techniques of reverse genetics has identified at least five chromosomal loci as the major causes for FHCM in diverse ethnic populations, suggesting substanti...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Ko YL,Teng MS,Tang TK,Chen JJ,Lee YS,Wu CW,Lien WP,Liew CC

    更新日期:1998-05-01 00:00:00

  • Neuroprotective effects of salvianolic acid B against oxygen-glucose deprivation/reperfusion damage in primary rat cortical neurons.

    abstract:BACKGROUND:Cerebral ischemia-reperfusion injury is the main reason for the loss of neurons in the ischemic cerebrovascular disease. Therefore, to deeply understand its pathogenesis and find a new target is the key issue to be solved. This research aimed to investigate the neuroprotective effects of salvianolic acid B (...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Wang Y,Jiang YF,Huang QF,Ge GL,Cui W

    更新日期:2010-12-01 00:00:00

  • "Target" and "Sandwich" Signs in Thigh Muscles have High Diagnostic Values for Collagen VI-related Myopathies.

    abstract:BACKGROUND:Collagen VI-related myopathies are autosomal dominant and recessive hereditary myopathies, mainly including Ullrich congenital muscular dystrophy (UCMD) and Bethlem myopathy (BM). Muscle magnetic resonance imaging (MRI) has been widely used to diagnosis muscular disorders. The purpose of this study was to ev...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.186638

    authors: Fu J,Zheng YM,Jin SQ,Yi JF,Liu XJ,Lyn H,Wang ZX,Zhang W,Xiao JX,Yuan Y

    更新日期:2016-08-05 00:00:00

  • High salt-induced weakness of anti-oxidative function of natriuretic peptide receptor-C and podocyte damage in the kidneys of Dahl rats.

    abstract:BACKGROUND:Atrial natriuretic peptide (ANP) and its natriuretic peptide receptors A (NPR-A) and C (NPR-C) are involved in the regulation of physiological and pathophysiological process of blood pressure. The present study aimed to determine the role of NPR-C in the development of salt-sensitive hypertension. METHODS:T...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.1097/CM9.0000000000000752

    authors: Zhu XL,Zhang T,Xu ZQ,Ma XC,Wang ZJ,Zou CW,Li JX,Jing HY

    更新日期:2020-05-20 00:00:00

  • Pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension: preliminary exploration in China.

    abstract:BACKGROUND:Pulmonary endarterectomy is safe and effective surgical treatment for chronic thromboembolic pulmonary hypertension. This study aimed to evaluate the efficacy of pulmonary endarterectomy in treatment of thromboembolic pulmonary hypertension. METHODS:A retrospective study of 15 patients who underwent pulmona...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Gu S,Liu Y,Su PX,Zhai ZG,Yang YH,Wang C

    更新日期:2010-04-20 00:00:00

  • Immunological studies of osteoarthritis in bipedal rats.

    abstract::Osteoarthritis (OA) models in bipedal rats were used to study the immune response, including the changes of IgG, antibody dependent cytotoxicity tests toward articular chondrocytes and the matrix. The results revealed significant difference between the bipedal and the quadruped rats. Immunological studies have proved ...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Chen YP,Yang Y,Chen BX

    更新日期:1991-03-01 00:00:00

  • Treatment of respiratory failure in metastatic pulmonary choriocarcinoma: an experience at Peking Union Medical College Hospital, China.

    abstract:BACKGROUND:Respiratory failure caused by metastatic pulmonary choriocarcinoma usually develops rapidly and is associated with a high mortality. The clinical management strategy is important in choriocarcinoma patients with acute respiratory failure. The objective of this study was to evaluate the clinical characteristi...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:

    authors: Shen Y,Ren T,Feng FZ,Wan XR,Xiang Y

    更新日期:2012-04-01 00:00:00

  • Recombinant Human Erythropoietin Augments Neovascularization Responses in a Neonatal Rat Model of Premature Brain Damage by Phosphatidylinositol 3 Kinase/Akt Pathway.

    abstract:BACKGROUND:Recombinant human-erythropoietin (rh-EPO) has therapeutic efficacy for premature infants with brain damage during the active rehabilitation and anti-inflammation. In the present study, we found that the rh-EPO was related to the promotion of neovascularization. Our aim was to investigate whether rh-EPO augme...

    journal_title:Chinese medical journal

    pub_type: 杂志文章

    doi:10.4103/0366-6999.202744

    authors: Yu DF,Zhu LH,Jiang L

    更新日期:2017-04-05 00:00:00