Abstract:
:Various species of Absidia, Aspergillus, Cunninghamella, Trichothecium, Penicillium, and Phanerochaete were found to transform rotenone to one or more metabolites. Two biotransformation products were isolated from a preparative-scale incubation of rotenone with Cunninghamella blakesleeana and identified as 1',2'-dihydro-1',2'-dihydroxyrotenone and 3'-hydroxyrotenone (amorphigenin). The catalytic reduction of the isopropylene side chain of rotenone resulted in the formation of 1',2'-dihydrorotenone. The latter was transformed by C. blakesleeana to 2'-hydroxy-1',2'-dihydrorotenone.
journal_name
Appl Environ Microbioljournal_title
Applied and environmental microbiologyauthors
Sariaslani FS,Rosazza JPdoi
10.1128/AEM.45.2.616-621.1983keywords:
subject
Has Abstractpub_date
1983-02-01 00:00:00pages
616-21issue
2eissn
0099-2240issn
1098-5336journal_volume
45pub_type
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