Abstract:
:We study the applicability of Van Kampen's linear noise approximation to the calculation of fluctuations in cells due to small number of molecules for simple genetic systems not previously considered. These systems include dimer formation and feedback. We explain why the linear noise approximation can be surprisingly effective, but also illustrate how it fails in a simple example when a protein probability distribution is not purely Gaussian.
journal_name
Phys Bioljournal_title
Physical biologyauthors
Hayot F,Jayaprakash Cdoi
10.1088/1478-3967/1/4/002keywords:
subject
Has Abstractpub_date
2004-12-01 00:00:00pages
205-10issue
3-4eissn
1478-3967issn
1478-3975pii
S1478-3967(04)84577-7journal_volume
1pub_type
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