Abstract:
:'ENVIRONMENT' is a computational platform that has been developed in the last few years with the aim to simulate stochastically the dynamics and stability of chemically reacting protocellular systems. Here we present and describe some of its main features, showing how the stochastic kinetics approach can be applied to study the time evolution of reaction networks in heterogeneous conditions, particularly when supramolecular lipid structures (micelles, vesicles, etc) coexist with aqueous domains. These conditions are of special relevance to understand the origins of cellular, self-reproducing compartments, in the context of prebiotic chemistry and evolution. We contrast our simulation results with real lab experiments, with the aim to bring together theoretical and experimental research on protocell and minimal artificial cell systems.
journal_name
Phys Bioljournal_title
Physical biologyauthors
Mavelli F,Ruiz-Mirazo Kdoi
10.1088/1478-3975/7/3/036002subject
Has Abstractpub_date
2010-08-11 00:00:00pages
036002issue
3eissn
1478-3967issn
1478-3975pii
S1478-3975(10)47613-Xjournal_volume
7pub_type
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