Abstract：
:PRED(BALB/c) is a computational system that predicts peptides binding to the major histocompatibility complex-2 (H2(d)) of the BALB/c mouse, an important laboratory model organism. The predictions include the complete set of H2(d) class I (H2-K(d), H2-L(d) and H2-D(d)) and class II (I-E(d) and I-A(d)) molecules. The prediction system utilizes quantitative matrices, which were rigorously validated using experimentally determined binders and non-binders and also by in vivo studies using viral proteins. The prediction performance of PRED(BALB/c) is of very high accuracy. To our knowledge, this is the first online server for the prediction of peptides binding to a complete set of major histocompatibility complex molecules in a model organism (H2(d) haplotype). PRED(BALB/c) is available at http://antigen.i2r.a-star.edu.sg/predBalbc/.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Zhang GL,Srinivasan KN,Veeramani A,August JT,Brusic Vdoi
10.1093/nar/gki479keywords:
subject
Has Abstractpub_date
2005-07-01 00:00:00pages
W180-3issue
Web Server issueeissn
0305-1048issn
1362-4962pii
33/suppl_2/W180journal_volume
33pub_type
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