Abstract：
:Controversy remains regarding the best surgical approach for toxic multinodular goiter (MNG). The aim of this study was to evaluate the results of various thyroid operations for managing toxic MNG. A group of 100 patients with toxic MNG were divided into three groups and managed with total thyroidectomy (TT; group I, n-17), near-total thyroidectomy (NTT; group II, n = 48), or bilateral subtotal thyroidectomy (BST; group III, n = 35). Patients were compared with regard to age, gender, surgical operations, complications, thyroid hormone status, duration of hospitalization, and the reoperation rate for incidentally found thyroid carcinomas. There were 14 men (14%) and 86 women (86%) with a mean age of 47.03 +/- 13.56 years (range 19-77 years). After the operation two patients had a hematoma, and one patient had a seroma. Four patients had unilateral vocal cord paralysis, and one had permanent paralysis. Moreover, 18 patients had transient and 2 patients permanent hypocalcemia. There was no significant difference between the groups regarding complications (p < 0.05). Permanent hypothyroidism was achieved in all patients in group I and 44 patients (92%) in group II, whereas in group III only 10 (29%) patients had hypothyroidism. Conversely, hyperthyroidism, both subclinical and clinical, was noted only in group III (12 patients, 34%) during follow-up. We think that TT and NTT are safe, effective approaches in the treatment of toxic MNG, preventing recurrence of thyrotoxicosis and reoperation for incidentally found thyroid cancers. The complication rates for TT and NTT were similar to that for BST. Hence these operation should be considered for patients referred for surgical treatment of toxic MNG.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Alimoglu O,Akdag M,Sahin M,Korkut C,Okan I,Kurtulmus Ndoi
10.1007/s00268-005-7767-3keywords:
subject
Has Abstractpub_date
2005-07-01 00:00:00pages
921-4issue
7eissn
0364-2313issn
1432-2323journal_volume
29pub_type
杂志文章abstract：BACKGROUND:Postoperative outcome prediction in elderly is based on preoperative physical status but its predictive value is uncertain. The goal was to evaluate the value of risk assessment performed perioperatively in predicting outcome in case of admission to an intensive care unit (ICU). METHODS:A total of 108 posts...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05742-5
更新日期：2020-12-01 00:00:00
abstract：:The primal need for nutrients is satisfied by mechanisms for sensing internal stores and detecting food; ATP is the most primitive signal. With increasing density of sensory neurons and glia (the primordial brain) and the emergence of autonomic neural activity throughout the endoderm, transmitters and other signaling ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0138-8
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:This study reviews the 15 year program of our Department of Pediatric Surgery for the treatment and follow-up of children born with a cleft in Benin and Togo. METHODS:We analyzed files of children born in Africa with a cleft. They were referred to us through a nongovernmental organization (NGO) between 1993...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1607-z
更新日期：2012-08-01 00:00:00
abstract：:Medical errors from communication failures are enormous during the perioperative period of cardiac surgical patients. As caregivers change shifts or surgical patients change location within the hospital, key information is lost or misconstrued. After a baseline cognitive study of information need and caregiver workflo...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0319-5
更新日期：2010-04-01 00:00:00
abstract：:The aim of this study was to investigate the effects of various surgical modalities directed at the cavity of hydatid cysts in patients with occult intrabiliary rupture. In this respect, 324 patients with hydatid cyst of the liver operated on during 1983-2003 were analyzed; among them, 39 patients with occult intrabil...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7571-5
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND:The World Health Organization Surgical Safety Checklist (SSC) has been widely implemented in an effort to decrease surgical adverse events. METHOD:This systematic literature review examined the effects of the SSC on postoperative outcomes. The review included 25 studies: two randomised controlled trials, 13...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-016-3519-9
更新日期：2016-08-01 00:00:00
abstract：:The most common causes of variceal bleeding are cirrhosis, schistosomiasis, and extrahepatic portal venous obstruction. The prognosis for an individual patient depends on the severity of the bleeding episode and the underlying liver function. Liver function is determined to a large extent by the underlying liver patho...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF00294397
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND:The stapled hemorrhoidopexy is reported to have a low recurrence while treating the major hemorrhoidal symptoms of bleeding and prolapse. The aim of this study is to obtain long-term results on the outcome of the stapled hemorrhoidopexy. METHODS:All patients with a hemorrhoidal disease grade III, who underw...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05065-0
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:The objectives of this study were to report the clinical and radiological characteristics and outcomes of a series of acute traumatic aortic injuries (ATAIs) with associated injury to major aortic abdominal visceral branches (MAAVBs). METHODS:From January 2000 to August 2011, 10 consecutive major blunt trau...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1536-x
更新日期：2012-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0351-5
更新日期：2010-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9589-6
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:Parathyroid glands can mimic thyroid follicular lesions on fine-needle aspiration (FNA) cytology and can lead to unnecessary or incorrect surgery. Newer molecular panel tests using next-generation sequencing (NGS) include analysis of cell type-specific gene expression profiles such as parathyroid. The study ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4548-3
更新日期：2018-09-01 00:00:00
abstract：:Noninvasive diagnosis of cavernous hemangioma of the liver is an important step in the investigation of patients with focal hepatic lesions since biopsy may result in life-threatening hemorrhage. To determine the diagnostic accuracy of 99m-technetium red blood cell (99mTc-RBC) imaging with tomography, 50 patients with...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01658668
更新日期：1990-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0693-1
更新日期：2007-05-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0818-4
更新日期：2011-01-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4759-7
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Ultrasound (US) and sestamibi (MIBI) are traditionally considered positive or negative. The purpose of this study was to define and test a new scoring system for MIBI and US and to determine whether this can improve their accuracy for primary hyperparathyroidism. METHODS:This is a prospective study of 200 c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1666-1
更新日期：2012-10-01 00:00:00
abstract：:In the original article Dennis Den Hartog's name was tagged incorrectly. It is correct as reflected here. ...
journal_title：World journal of surgery
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00268-019-04957-5
更新日期：2019-05-01 00:00:00
abstract：:Angiogenesis is essential for tumor growth and metastasis. An association between microvessel density, a measure of tumor angiogenesis, and conventional prognostic variables has been shown for many tumor entities. For Barrett's carcinoma, the results are controversial. Immature vessels formed in tumors are structurall...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7286-7
更新日期：2004-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-014-2578-z
更新日期：2014-09-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3571-5
更新日期：2016-09-01 00:00:00
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journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s002689900007
更新日期：1996-01-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01658871
更新日期：1989-09-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-015-3220-4
更新日期：2015-12-01 00:00:00
abstract：:The expression of Fas ligand on tumor cells may counterattack the host's immunity and worsen the prognosis. Knowledge of the prognostic impact of Fas ligand on patients with hepatocellular carcinoma (HCC) after hepatectomy is still limited. Fas ligand expression in HCCs was examined in 59 patients who underwent hepate...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7254-2
更新日期：2004-08-01 00:00:00
abstract：:Cardiovascular disease [atherosclerosis and subsequent myocardial infarction (MI)] has been associated with primary hyperparathyroidism. We aimed at studying cardiovascular events before and after surgery and mortality after surgery for primary hyperparathyroidism using a historical follow-up design. A total of 674 pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6541-z
更新日期：2003-02-01 00:00:00
abstract：BACKGROUND:As more patients undergo diagnostic thyroid surgery, the development of posthemithyroidectomy hypothyroidism is becoming a major concern. We hypothesized that the preoperative thyrotropin (thyroid-stimulating hormone, TSH) level and ultrasonographically measured thyroid volume, both commonly available in thy...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9717-3
更新日期：2008-11-01 00:00:00
abstract：:Some 25%-70% of sporadic medullary thyroid carcinomas (MTCs) are associated with somatic mutations within the RET proto-oncogene. In a significant number of MTCs, however, no such genetic variations can be detected, which implies alternative pathogenic molecular alterations. To assess altered RET mutation-specific gen...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7748-y
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:Among burn patients, research is conflicted, but may suggest that females are at increased risk of mortality, despite the opposite being true in non-burn trauma. Our objective was to determine whether sex-based differences in burn mortality exist, and assess whether patient demographics, comorbid conditions,...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05165-x
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:New medical therapies available to ulcerative colitis (UC) patients have influenced operative mortality for patients requiring colectomy. We sought to examine trends in treatment and outcome for UC patients treated surgically. METHODS:A review of 36,447 UC patients from the Nationwide Inpatient Sample was p...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0910-9
更新日期：2011-03-01 00:00:00
