Biodegradable X-ray markers of controlled radio-opacity. Temporary position measurements in bone.

Abstract:

:In order to analyze X-ray markers for potential use in biodegradable implants or radiostereogrammatic analysis (RSA), we combined iopromide contrast fluid with biodegradable calcium phosphate cement. The radio-opacity of 10 x 10 mm markers containing different iodine concentrations (0, 120, 240, 360 and 720 mg per gram cement) was compared to an aluminium wedge of increasing (1-10 mm) thickness. The addition of iopromide increased the radio-opacity in a dose-dependent manner, which was comparable to 9-mm aluminium at concentrations of 240-720 mg/g. Radiographs of markers placed in explanted rabbit and in human femora were made to investigate the clinical accuracy for position determination. Markers of 1 x 1 mm (120 mg/g) were clearly discernable in all femora, and could be used to adequately measure distances of 5-45 mm (accuracy 0.10-2.19 mm). These markers might be embedded in biodegradable implants or used as temporary markers in the bone to analyze postoperative position on radiographs.

journal_name

Acta Orthop

journal_title

Acta orthopaedica

authors

Stallmann HP,Faber C,Plokker HM,Wuisman PI

doi

10.1080/00016470510030445

keywords:

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

122-7

issue

1

eissn

1745-3674

issn

1745-3682

pii

KTVR7KRT8T6YDN43

journal_volume

76

pub_type

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