Abstract：
:Transposable elements are often considered as selfish DNA sequences able to invade the genome of their host species. Their evolutive dynamics are complex, due to the interaction between their intrinsic amplification capacity, selection at the host level, transposition regulation, and genetic drift. Here, we propose modeling the first steps of TE invasion, i.e., just after a horizontal transfer, when a single copy is present in the genome of one individual. If the element has a constant transposition rate, it will disappear in most cases: the elements with low-transposition rate are frequently lost through genetic drift, while those with high-transposition rate may amplify, leading to the sterility of their host. Elements whose transposition rate is regulated are able to successfully invade the populations, thanks to an initial transposition burst followed by a strong limitation of their activity. Self-regulation or hybrid dysgenesis may thus represent some genome-invasion parasitic strategies.
journal_name
Geneticsjournal_title
Geneticsauthors
Le Rouzic A,Capy Pdoi
10.1534/genetics.104.031211keywords:
subject
Has Abstractpub_date
2005-02-01 00:00:00pages
1033-43issue
2eissn
0016-6731issn
1943-2631pii
169/2/1033journal_volume
169pub_type
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