Long term follow-up of reconstruction with allogeneic mandibular bone crib packed with autogenous particulate cancellous bone marrow.

Abstract:

:Allogeneic mandibular bone processed by the deep frozen method was used as a biologic crib for mandibular reconstruction. The allogeneic mandible is biocompatible, bioresorbable, of low antigenicity and provides the morphology for symphysis contour, angle of mandible and dental arch form. The particulate cancellous bone marrow (PCBM) contains marked osteogenic potential of hematopoietic marrow, which promotes osteogenesis. The cancellous marrow graft lacks structure and requires a crib to house it during the bone regeneration to the consolidation phase. Fresh frozen mandible was hollowed out for packing with PCBM prior to securing it to the defect by a rigid fixation method. Four cases of large mandibular defects resulting from treatment of benign odontogenic tumors were reconstructed utilizing this technique. All cases showed excellent facial contour and function satisfactorily in mastication and pronunciation. Complete graft incorporation and restoration of the osseous continuities were observed for four to 12 years after the operation.

journal_name

Cell Tissue Bank

journal_title

Cell and tissue banking

authors

Rochanawutanon S,Suddhasthira T,Pairuchvej V,Vajaradul Y

doi

10.1023/A:1023602717328

keywords:

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

183-97

issue

3

eissn

1389-9333

issn

1573-6814

pii

5113989

journal_volume

3

pub_type

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