当前位置： SCI文献检索 > BRAIN RESEARCH BULLETIN期刊下所有文献 > Lesions of the dorsal noradrenergic bundle augment the renin response to blood loss but do not alter hypothalamic Fos expression.

Lesions of the dorsal noradrenergic bundle augment the renin response to blood loss but do not alter hypothalamic Fos expression.

Abstract：

:The goal of this study was to determine if the dorsal noradrenergic bundle (DNAB) plays an essential role in mediating increased plasma renin activity (PRA) and hypothalamic activation, as indicated by increased Fos expression, in response to a small volume blood loss in unanesthetized animals. Male Sprague-Dawley rats were prepared with bilateral 6-hydroxydopamine or sham lesions of the dorsal noradrenergic bundle. In both groups of animals, blood pressure decreased by only 10-15 mmHg following hemorrhage (10 ml/kg over 15 min). Plasma renin activity increased similarly in both groups after 5 ml/kg blood loss, but showed a significantly greater increase after 10 ml/kg blood loss in animals with 6-hydroxydopamine lesions than in those with sham lesions (increase of 13.8 +/- 2.0 ng/ml/h versus 8.4 +/- 1.2 ng/ml/h; P < 0.025). There were numerous Fos-immunoreactive cell nuclei in the supraoptic nucleus (SON) and parvicellular paraventricular hypothalamic nucleus (PVN) of hemorrhaged animals. The number of Fos-positive neurons did not differ between groups, indicating that the dorsal noradrenergic bundle does not convey the primary drive for supraoptic and paraventricular nucleus activation during blood loss. However, one or more of the forebrain regions innervated by the dorsal noradrenergic bundle may attenuate the sympathetic outflow that initiates renin release in response to hemorrhage.

journal_name

Brain Res Bull

journal_title

Brain research bulletin

authors

Jaworski RL,Blair ML

doi

10.1016/j.brainresbull.2004.03.008

keywords:

subject

Has Abstract

pub_date

2004-07-15 00:00:00

pages

451-9

issue

6

eissn

0361-9230

issn

1873-2747

pii

S0361923004001042

journal_volume

63

pub_type

杂志文章

相关文献

BRAIN RESEARCH BULLETIN文献大全
  • Spinal projections from the nucleus locus coeruleus and nucleus subcoeruleus in the cat and monkey as demonstrated by the retrograde transport of horseradish peroxidase.

    abstract：:The rostral pons of the cat and rhesus monkey were examined for the presence of labeled cells following injections of horseradish peroxidase (HRP) into the lumbar spinal cord. Labeled cells were found in the ipsilateral dorsolateral pontine tegmentum and in the contralateral ventrolateral pontine reticular formation. ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(76)90072-1

    authors： Hancock MB,Fougerousse CL

    更新日期：1976-03-01 00:00:00

  • Hemokinin-1 is an important mediator of pain in mouse models of neuropathic and inflammatory mechanisms.

    abstract：:The Tac4 gene-derived hemokinin-1 (HK-1) is present in pain-related regions and activates the tachykinin NK1 receptor, but with binding site and signaling pathways different from Substance P (SP). NK1 receptor is involved in nociception, but our earlier data showed that it has no role in chronic neuropathic hyperalges...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2019.01.015

    authors： Hunyady Á,Hajna Z,Gubányi T,Scheich B,Kemény Á,Gaszner B,Borbély É,Helyes Z

    更新日期：2019-04-01 00:00:00

  • Atorvastatin attenuates the antinociceptive tolerance of morphine via nitric oxide dependent pathway in male mice.

    abstract：:The development of morphine-induced antinociceptive tolerance limits its therapeutic efficacy in pain management. Atorvastatin, or competitive inhibitor of 3-hydroxy-methyl-glutaryl coenzyme A (HMG-CoA) reductase, is mainstay agent in hypercholesterolemia treatment. Beyond the cholesterol-lowering activity, exploratio...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2016.07.002

    authors： Hassanipour M,Amini-Khoei H,Shafaroodi H,Shirzadian A,Rahimi N,Imran-Khan M,Rezayat SM,Dehpour A

    更新日期：2016-07-01 00:00:00

  • The brain 5HTergic response to an acute sound stress in rats with generalized (absence and audiogenic) epilepsy.

    abstract：:The brain serotoninergic (5HTergic) system of epileptic subjects can influence their vulnerability to stress. We studied the putative dependency of 5HT neurotransmission parameters on emotional stress, and the presence, types and severity of seizures using rats with genetic generalized (absence and/or audiogenic) epil...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2006.03.008

    authors： Midzyanovskaya IS,Kuznetsova GD,van Luijtelaar EL,van Rijn CM,Tuomisto L,Macdonald E

    更新日期：2006-05-31 00:00:00

  • Role of Pax6 in forebrain regionalization.

    abstract：:Pax6 is a highly conserved transcription factor essential for the development of the eyes in vertebrate and invertebrate species. It is also required for normal development of many regions of the central nervous system, including the mammalian forebrain, hindbrain and spinal cord. In the forebrain, it is expressed in ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章,评审

    doi：10.1016/j.brainresbull.2005.02.006

    authors： Manuel M,Price DJ

    更新日期：2005-09-15 00:00:00

  • NMDA receptor activity in learning spatial procedural strategies I. The influence of hippocampal lesions.

    abstract：:To acquire knowledge about the environment two types of learning are necessary: declarative localizatory learning about where environmental cues and the subject are, and procedural learning about how to explore and move around the environment. Experimental data indicate that hippocampal regions are involved in spatial...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2006.06.006

    authors： Leggio MG,Federico F,Neri P,Graziano A,Mandolesi L,Petrosini L

    更新日期：2006-10-16 00:00:00

  • Anterograde transport of HSV-1 and HSV-2 in the visual system.

    abstract：:The anterograde spread of herpesvirus in the visual system subsequent to retinitis has been observed clinically. We compared the ability of two well-studied Herpes simplex virus (HSV) strains to be transported in the anterograde direction in the hamster visual system: strain McIntyre, representing HSV-1, and strain 18...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(92)90038-y

    authors： Norgren RB Jr,McLean JH,Bubel HC,Wander A,Bernstein DI,Lehman MN

    更新日期：1992-03-01 00:00:00

  • Intraspinal transplants of serotonergic neurons in the adult rat.

    abstract：:Adult male Sprague-Dawley rats were made paraplegic by a complete transection of the spinal cord at lower thoracic level. One week later they were transplanted, below the level of the section, with a cell suspension prepared from the raphe region of 14-day embryos. After survival periods of 10 days to 1 year, the anim...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(89)90136-6

    authors： Privat A,Mansour H,Rajaofetra N,Geffard M

    更新日期：1989-01-01 00:00:00

  • Inhibitory effects of acetylcholine on aggressive-defense reaction induced by electrical stimulation of the hypothalamus in cats.

    abstract：:The effects of ventral amygdalofugal pathways (VAF) or stria terminalis (ST) on the hypothalamic aggressive-defense (rage) reaction were examined in fifteen cats. After bilateral electrolytic lesions of the VAF or ST, 0.5 pmol of acetylcholine (ACh) was injected into the VMH and electrical stimulation was applied. The...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(86)90178-4

    authors： Kono R,Tashiro N,Nakao H

    更新日期：1986-04-01 00:00:00

  • A driving simulation task: correlations with Multiple Sleep Latency Test.

    abstract：:Sleepiness and driving is a dangerous combination that causes thousands of crashes each year resulting in injury and death. In the last few years, driving simulators have been used to study the performance decrements associated with drowsiness. We correlated performances of a driving simulation task in healthy volunte...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2003.12.015

    authors： Pizza F,Contardi S,Mostacci B,Mondini S,Cirignotta F

    更新日期：2004-06-30 00:00:00

  • Image analysis of catecholamine fluorescence.

    abstract：:Image analysis methods are being developed for measuring the density and distribution of perivascular noradrenergic nerves and their varicosities, demonstrated by fluorescence histochemistry. Image analysis is recommended in comparison with other methods for the quantitation of fluorescence, because image resolution i...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(82)90123-x

    authors： Cowen T,Burnstock G

    更新日期：1982-07-01 00:00:00

  • Effect of central tachykinins, alone and with angiotensin II, on drinking in pigs and goats.

    abstract：:Central administration of the tachykinins, eledoisin or physalaemin has been reported to produce significant water intake in pigeons but inhibition of stimulated drinking in rats. In this paper it is shown that high and low doses of these two tachykinins injected centrally in two much larger species, goats and pigs, d...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(90)90247-w

    authors： Thornton SN,Baldwin BA

    更新日期：1990-07-01 00:00:00

  • Alterations in grooming activity and syntax in heterozygous SERT and BDNF knockout mice: the utility of behavior-recognition tools to characterize mutant mouse phenotypes.

    abstract：:Serotonin transporter (SERT) and brain-derived neurotrophic factor (BDNF) are key modulators of molecular signaling, cognition and behavior. Although SERT and BDNF mutant mouse phenotypes have been extensively characterized, little is known about their self-grooming behavior. Grooming represents an important behaviora...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2012.08.004

    authors： Kyzar EJ,Pham M,Roth A,Cachat J,Green J,Gaikwad S,Kalueff AV

    更新日期：2012-12-01 00:00:00

  • Role of P2 receptors in normal brain development and in neurodevelopmental psychiatric disorders.

    abstract：:The purinergic signaling system, including P2 receptors, plays an important role in various central nervous system (CNS) disorders. Over the last few decades, a substantial amount of accumulated data suggest that most P2 receptor subtypes (P2X1, 2, 3, 4, 6, and 7, and P2Y1, 2, 6, 12, and 13) regulate neuronal/neurogli...

    journal_title：Brain research bulletin

    pub_type： 杂志文章,评审

    doi：10.1016/j.brainresbull.2019.01.030

    authors： Huang L,Otrokocsi L,Sperlágh B

    更新日期：2019-09-01 00:00:00

  • Tamoxifen and mifepriston modulate nicotine induced conditioned place preference in female rats.

    abstract：:An increasing number of studies suggest that nicotine/tobacco addiction is modulated by ovarian hormones. The levels of estrogen and progesterone appear to be important in the success of quit attempts and smoking cessation. In women smokers with the diagnosis or risk of breast cancer, the estrogen receptor modulator t...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2011.01.013

    authors： Yararbas G,Pogun S

    更新日期：2011-04-05 00:00:00

  • Unified and disease specific alterations to brain structure in patients across six categories of mental disorders who experience own-thought auditory verbal hallucinations: A pilot study.

    abstract：OBJECTIVE:To explore the unified and disease specific structural features of the brain in patients spanning six mental disorders who experience own-thought auditory verbal hallucinations (OTAVH). METHODS:A pilot study was conducted on 25 patients with schizophrenia (FUSCH-OTAVH), 20 patients with major depression diso...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2020.04.001

    authors： Zhuo C,Lin X,Wang C,Song X,Xu X,Li G,Xu Y,Tian H,Zhang Y,Wang W,Zhou C

    更新日期：2020-07-01 00:00:00

  • Reevaluation of the plasticity in the rat supraoptic nucleus after chronic dehydration using immunogold for oxytocin and vasopressin at the ultrastructural level.

    abstract：:It has been shown that during physiological stimuli, such as dehydration, supraoptic nucleus (SON) neurons undergo profound morphological changes. However, little is known about how much each type of cell, oxytocin (OT) or vasopressin (VP), contributes to this plasticity during dehydration. Using postembedding immunog...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(92)90256-w

    authors： Marzban F,Tweedle CD,Hatton GI

    更新日期：1992-05-01 00:00:00

  • Effects of microinjections of substance P into the suprachiasmatic nucleus region on hamster wheel-running rhythms.

    abstract：:The suprachiasmatic nucleus (SCN) receives a direct retinal projection, which in rats includes substance P (SP)-immunoreactive retinal ganglion cells. While SP has been shown to have neurophysiological effects on SCN cells in Syrian hamsters and rats, it is not known what effects SP in the SCN has on circadian rhythms...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/s0361-9230(96)00371-1

    authors： Piggins HD,Rusak B

    更新日期：1997-01-01 00:00:00

  • Somatic labeling of the medial terminal nucleus of the accessory optic system with WGA-HRP injected into the rat occipital cortex.

    abstract：:Neuronal cell bodies in the medial terminal nucleus of the accessory optic system (MTN) were labeled with WGA-HRP which was injected ipsilaterally into the occipital cortex in the rat. We suggest that the label was first transported anterogradely to the pretectal nucleus of the optic tract, then moved transneuronally ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(87)90043-8

    authors： Takada M,Li ZK,Hattori T

    更新日期：1987-01-01 00:00:00

  • Locus coeruleus stimulation modulates olfactory bulb evoked potentials.

    abstract：:Field-evoked potentials from the main olfactory bulb in response to stimulation of the olfactory nerve and lateral olfactory tract were measured without and with conditioning stimulation of the locus coeruleus noradrenergic system. The locus coeruleus conditioning stimulus suppressed or inhibited the late components o...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(87)90213-9

    authors： Perez H,Hernandez A,Almli CR

    更新日期：1987-06-01 00:00:00

  • Magnetic resonance imaging studies of the brains of anesthetized rats treated with manganese chloride.

    abstract：:An understanding of the distribution of manganese ions in the brain is of interest in connection with the development of an understanding of the neurotoxicity of this element. Information about the time dependent biodistribution of manganese ions in the brains of intact rats subsequent to single IP injections of MnCl2...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(89)90152-4

    authors： London RE,Toney G,Gabel SA,Funk A

    更新日期：1989-09-01 00:00:00

  • Molecular and cellular mechanisms of opiate action: studies in the rat locus coeruleus.

    abstract：:We have studied the molecular and cellular mechanisms underlying the acute and chronic effects of opiate on neurons of the rat locus coeruleus (LC). Acutely, opiates inhibit LC neurons by activating K+ channels and inhibiting a novel sodium-dependent inward current. Both of these actions are mediated via pertussis tox...

    journal_title：Brain research bulletin

    pub_type： 杂志文章,评审

    doi：10.1016/0361-9230(94)90166-x

    authors： Nestler EJ,Alreja M,Aghajanian GK

    更新日期：1994-01-01 00:00:00

  • Type of memory or attention? Impairments after lesions of the hippocampus and limbic ventral tegmentum.

    abstract：:An animal with an unimpaired "reference" memory can distinguish between alternatives that belong to a rewarded set and those that are unrewarded. An animal with an unimpaired "working" memory can distinguish between alternatives where it has been rewarded (e.g., food has been eaten and not replaced) and those where it...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(81)90086-1

    authors： Oades RD

    更新日期：1981-08-01 00:00:00

  • Geranylgeranylacetone, an inducer of HSP 70, attenuates REM sleep rebound after sleep deprivation.

    abstract：:The effect of pretreatment of geranylgeranylacetone (GGA), an inducer of heat shock protein (HSP) 70, on responses in sleep and core body temperature (Tcore) against sleep deprivation (SD) was examined in rats. After 3 days of GGA or vehicle injection, a 6-h period of SD was performed. During the recovery period, both...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2006.02.004

    authors： Wada T,Sei H,Kusumoto K,Kitaoka K,Chikahisa S,Rokutan K,Morita Y

    更新日期：2006-04-28 00:00:00

  • Differential interactive effects of gliotoxin and MPTP in the substantia nigra and the locus coeruleus in BALB/c mice.

    abstract：:We have previously demonstrated that chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) infusion to the substantia nigra (SN) and the locus coeruleus (LC) both produce a long-lasting neurotoxicity on dopamine (DA) and norepinephrine (NE) neurons in these two areas, respectively. In the present study, we furth...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(93)90215-w

    authors： Chang FW,Wang SD,Lu KT,Lee EH

    更新日期：1993-01-01 00:00:00

  • Reduction of histamine H1 receptor binding induced by high-fat diet can be prevented by DHA and dietary fiber in specific brain areas of male rats.

    abstract：:High-fat (HF) diet and obesity are risk factors for a number of mental health problems including depression, cognitive dysfunction, dementia, and neurodegenerative diseases. Histamine H1 receptors (H1Rs) are involved in many of these conditions. This study examined H1R receptor binding density in the brain of male rat...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2013.06.003

    authors： Wu Z,Yu Y,Wu Y,Patch C,Szabo A,Huang XF

    更新日期：2013-08-01 00:00:00

  • Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease'.

    abstract：:The cytoskeleton is the major intracellular structure that determines the morphology of neurons and maintains their structural integrity. It is therefore not surprising that a disturbance of cytoskeletal structure and functionunderlies many neurodegenerative diseases. This special issue brings together current informa...

    journal_title：Brain research bulletin

    pub_type： 社论

    doi：10.1016/j.brainresbull.2016.08.003

    authors： Brandt R,Götz J

    更新日期：2016-09-01 00:00:00

  • Temporal and spatial dynamics of peripheral afferent-evoked activity in the dorsal horn recorded in rat spinal cord slices.

    abstract：:In the present study, multi-electrode array recording was used to examine dorsal horn activity following stimulation of primary afferents in a rat dorsal root attached-spinal cord slice preparation. The multi-electrode array probe was placed under the dorsal horn slice and local field potentials evoked by stimulation ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2017.04.012

    authors： Yu F,Zhao ZY,He T,Yu YQ,Li Z,Chen J

    更新日期：2017-05-01 00:00:00

  • Effect of progesterone on monoamine turnover in the brain of the estrogen-primed rat.

    abstract：:The effect of progesterone (P) on monoamine levels and turnover was evaluated in 8 brain nuclei in estrogen-primed rats. Animals were subcutaneously (SC) injected with P or vehicle 21 hours after SC treatment with 5 micrograms of estradiol benzoate (EB). EB-primed animals treated with P showed high levels of lordosis ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(87)90085-2

    authors： Renner KJ,Krey LC,Luine VN

    更新日期：1987-08-01 00:00:00

  • Quantitative analysis of neural plate thickness and cell density during gastrulation in the chick embryo.

    abstract：:We quantitatively analyzed the developing prospective neural and non-neural ectoderm during chicken gastrulation on semithin transverse sections. At stage PS8 (primitive streak stage 8 of Lopez-Sanchez et al. [C. Lopez-Sanchez, L. Puelles, V. Garcia-Martinez, L. Rodriguez-Gallardo, Morphological and molecular analysis...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2007.10.061

    authors： Rodríguez-Gallardo L,Hidalgo-Sánchez M,Sánchez-Arrones L,Prior L,Puelles L

    更新日期：2008-03-18 00:00:00