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In vivo and in vitro effect of latex of Calotropis procera on gastrointestinal smooth muscles.

Abstract：

:The present study was carried out to evaluate the effect of dry latex (DL) of Calotropis procera on smooth muscles of gastrointestinal tract. Oral administration of DL to rats (50-1000 mg/kg) produced a dose-dependent decrease in intestinal transit along with a decrease in intestinal content as compared to control group. At lower doses DL produced dose-dependent contractions of gastrointestinal smooth muscles in vitro (rabbit ileum and fundus of rat stomach) that was followed by desensitization at higher doses.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Kumar VL,Shivkar YM

doi

10.1016/j.jep.2004.04.013

keywords:

subject

Has Abstract

pub_date

2004-08-01 00:00:00

pages

377-9

issue

2-3

eissn

0378-8741

issn

1872-7573

pii

S0378874104002041

journal_volume

93

pub_type

杂志文章

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