Abstract：
:Eight amides, pellitorine (1), guineensine (2), brachystamide B (3), sarmentine (4), brachyamide B (5), 1-piperettyl pyrrolidine (6), 3',4',5'-trimethoxycinnamoyl pyrrolidine (7) and sarmentosine (8), two lignans, (+)-asarinin (9) and sesamin (10), and four other compounds, 1-(3,4-methylenedioxyphenyl)-1E-tetradecene (11), methyl piperate (12) and a mixture of beta-sitosterol (13) and stigmasterol (14), were isolated from the fruits of Piper sarmentosum (Piperaceae). This is the first reported isolation of compounds 2, 3, 5, 6, 7, 9, 10 and 12 from this plant species. Their structures were established from spectral data. These compounds were evaluated in antituberculosis and antiplasmodial tests. The results showed that compounds 4 and 6 exhibited both activities while compounds 1, 2, 5, 8 and 11 showed only antituberculosis activity. This is the first report of the antituberculosis and antiplasmodial activities for these compounds.
journal_name
J Ethnopharmacoljournal_title
Journal of ethnopharmacologyauthors
Rukachaisirikul T,Siriwattanakit P,Sukcharoenphol K,Wongvein C,Ruttanaweang P,Wongwattanavuch P,Suksamrarn Adoi
10.1016/j.jep.2004.01.022keywords:
subject
Has Abstractpub_date
2004-08-01 00:00:00pages
173-6issue
2-3eissn
0378-8741issn
1872-7573pii
S0378874104002168journal_volume
93pub_type
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journal_title：Journal of ethnopharmacology
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journal_title：Journal of ethnopharmacology
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