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The distribution of 5-HT3 recognition sites in the marmoset brain.

Abstract：

:The distribution of the binding of [3H]GR65630 (0.2 nM) to putative 5-HT3 recognition sites in the brain of the common marmoset was assessed using autoradiography. Specific binding was heterogeneously distributed with the highest densities found in discrete nuclei of the lower medulla (nucleus tractus solitarii, dorsal motor nucleus of the vagus nerve, nucleus of spinal trigeminal nerve tract and the area postrema). In forebrain areas, relatively high binding densities were located in the medial habenula nucleus and the hippocampus (CA3, CA4 and fascia dentata). Low levels of specific binding in the rest of the forebrain hindered quantification.

journal_name

Eur J Pharmacol

journal_title

European journal of pharmacology

authors

Jones DN,Barnes NM,Costall B,Domeney AM,Kilpatrick GJ,Naylor RJ,Tyers MB

doi

10.1016/0014-2999(92)90609-8

keywords:

subject

Has Abstract

pub_date

1992-04-29 00:00:00

pages

63-7

issue

1

eissn

0014-2999

issn

1879-0712

pii

0014-2999(92)90609-8

journal_volume

215

pub_type

杂志文章

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