Renal AA amyloidosis in a patient with Bence Jones proteinuria and ankylosing spondylitis.

abstract：:Five cases of inflammatory pseudotumour of the liver are reported and compared with seven individual previously published case reports. Clinical presentation was variable but often comprised low grade intermittent fever, vague abdominal symptoms, and a history of weight loss. Leucocytosis, raised erythrocyte sedimenta...

journal_title：Journal of clinical pathology

authors： Anthony PP,Telesinghe PU

更新日期：1986-07-01 00:00:00

abstract：:A rapid and reproducible technique for in situ hybridisation, using biotin labelled probes for the Y chromosome, human DNA, hepatitis B virus DNA and cytomegalovirus DNA on formalin fixed, paraffin embedded liver tissue, was developed. The degree of proteolytic digestion of tissue specimens is critical to ensure adequ...

journal_title：Journal of clinical pathology

authors： Naoumov NV,Alexander GJ,Eddleston AL,Williams R

更新日期：1988-07-01 00:00:00

abstract：:By means of enzyme immunoassays based on two monoclonal antibodies with specificities for distinct forms of placental type alkaline phosphatase (Pl-ALP), together with L-leucine inhibition studies, it has been possible to distinguish the Nagao type carcinoplacental enzyme from other placental type alkaline phosphatase...

journal_title：Journal of clinical pathology

authors： McLaughlin PJ,Twist AM,Evans CC,Johnson PM

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Fatty liver disease (FLD), of either alcoholic (AFLD) or non-alcoholic (NAFLD) aetiologies, is characterised histologically by features that are lobulocentric that typically affect zone 3, in contrast with portal-based inflammation characteristics of other forms of chronic liver disease. AIM:The authors aim...

journal_title：Journal of clinical pathology

authors： Rakha EA,Adamson L,Bell E,Neal K,Ryder SD,Kaye PV,Aithal GP

更新日期：2010-09-01 00:00:00

abstract：:An imprint culture technique has been employed to study the prevalence and intraoral distribution of Candida albicans in 16 patients with Sjögren's syndrome and in 16 healthy controls matched for age, sex, and dental status. The prevalence and intraoral density of C. albicans was found to be significantly higher at al...

journal_title：Journal of clinical pathology

authors： Tapper-Jones L,Aldred M,Walker DM

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterised by the presence of various laboratory abnormalities but the precise role of laboratory staff in initiating clinical referral and subsequent biopsy is not clear. OBJECTIVE:To examine the impact of laboratory abnormalities in the inv...

journal_title：Journal of clinical pathology

authors： Sinclair D,Spedding A,Young R

更新日期：2006-04-01 00:00:00

abstract：AIM:To investigate the natural history of patients with non-alcoholic steatohepatitis by means of a prospective histological study. METHODS:One thousand five hundred and seventy one patients underwent liver biopsy at the Western Infirmary in Glasgow during the 10 year period 1985 to 1994. All biopsies were reported by...

journal_title：Journal of clinical pathology

authors： Evans CD,Oien KA,MacSween RN,Mills PR

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Transcription factors of the forkhead box P (FOXP1-4) family have been implicated in various human cancer types before. The relevance and role of neuronal transcription factor FOXP2 in prostate cancer is unknown. METHODS:A tissue microarray containing samples from more than 11 000 prostate cancers ...

journal_title：Journal of clinical pathology

authors： Stumm L,Burkhardt L,Steurer S,Simon R,Adam M,Becker A,Sauter G,Minner S,Schlomm T,Sirma H,Michl U

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Inflammatory cells contribute to the growth and spread of human malignancies by producing molecules that enhance tumour invasiveness. AIMS:To characterise the inflammatory infiltrate in pancreatic ductal adenocarcinoma and to analyse its contribution to angiogenesis and its prognostic relevance. METHODS:Im...

journal_title：Journal of clinical pathology

authors： Esposito I,Menicagli M,Funel N,Bergmann F,Boggi U,Mosca F,Bevilacqua G,Campani D

更新日期：2004-06-01 00:00:00

abstract：:The case records and pathology of all children with kidney tumours treated in the West Midlands Health Authority Region (WMHAR) from 1957 to 1986 were reviewed. The histology was reviewed by a panel of three paediatric pathologists. Thirteen (6%) out of 211 cases were considered to have congenital mesoblastic nephroma...

journal_title：Journal of clinical pathology

authors： Barrantes JC,Toyn C,Muir KR,Parkes SE,Raafat F,Cameron AH,Marsden HB,Mann JR

更新日期：1991-04-01 00:00:00

abstract：:Immune and non-immune rubella sera were examined in the haemagglutination inhibition (HAI) test to evaluate the removal of lipoprotein non-specific inhibitors (NSI) of haemagglutination after kaolin and manganous chloride/heparin treatments. The sera were titrated fresh or after lipoprotein deterioration brought about...

journal_title：Journal of clinical pathology

authors： Shortridge KF

更新日期：1977-05-01 00:00:00

abstract：:Publications describing aspects of the coccidian protozoan parasite Cryptosporidium, increased greatly during 1983 and 1984 as a result of not only increasing veterinary interest but also in the role of the parasite in the newly recognised acquired immune deficiency syndrome (AIDS). The reports reflected widespread co...

journal_title：Journal of clinical pathology

authors： Casemore DP,Sands RL,Curry A

更新日期：1985-12-01 00:00:00

abstract：:MUCs are glycoproteins with various roles in homeostasis and carcinogenesis. Among other actions, MUC1 may inhibit cell-cell and cell-stroma interactions and function as a signal transducer, participating in cancer progression. In contrast, MUC2 is normally found only in goblet cells, where it contributes to the prote...

journal_title：Journal of clinical pathology

authors： Levi E,Klimstra DS,Andea A,Basturk O,Adsay NV

更新日期：2004-05-01 00:00:00

abstract：:Evaluation of histological diagnosis requires an index of agreement (to measure repeatability and validity) together with a method of assessing bias. Cohen's kappa statistic appears to be the most suitable tool for measuring levels of agreement, which if unsatisfactory may be caused by bias. Further study of bias is p...

journal_title：Journal of clinical pathology

authors： Silcocks PB

更新日期：1983-11-01 00:00:00

abstract：:Candida spp are the fourth most common group of nosocomial pathogens isolated from patients on medical, surgical, and intensive care wards. Polymicrobial candidaemia has rarely been described. The diagnosis of candidaemia from peripheral blood smears has not been widely reported. This report describes the case of a yo...

journal_title：Journal of clinical pathology

authors： Yera H,Poulain D,Lefebvre A,Camus D,Sendid B

更新日期：2004-02-01 00:00:00

abstract：:The detection of lymphoid cells by routine examination of the urine after renal allotransplantation has proved to be a useful early indication of rejection. In a study of 36 rejection episodes, 20 (56%) were associated with a significant number of lymphocytes in the urine. The incidence was much higher when rejection ...

journal_title：Journal of clinical pathology

authors： Papadimitriou M,Chisholm GD,Kulatilake AE,Shackman R

更新日期：1970-03-01 00:00:00

abstract：:Attempts to detect hepatitis B antigen in faeces and bile should take into account the degradation and disappearance of the surface antigens in an environment containing proteolytic enzymes in the presence of bile salts as in the intestinal lumen. The cores of the Dane particles are much more stable than the surface a...

journal_title：Journal of clinical pathology

authors： Moodie JW,Stannard LM,Kipps A

更新日期：1974-09-01 00:00:00

abstract：BACKGROUND:The Wnt pathway is important in cell signalling transduction and is involved in the pathogenesis of multiple tumour types. A comprehensive analysis of the expression of Wnt signalling pathway proteins in mammary phyllodes tumours (PTs) has not been previously performed. AIMS:To evaluate the immunohistochemi...

journal_title：Journal of clinical pathology

authors： Karim RZ,Gerega SK,Yang YH,Horvath L,Spillane A,Carmalt H,Scolyer RA,Lee CS

更新日期：2009-11-01 00:00:00

abstract：AIMS:To determine the suitability of primary gel separation tubes for the storage of frozen sera intended for serological testing. METHODS:Blood samples from 102 patients were collected into gel separation tubes. The sera from these samples were split between the primary gel separation tubes and conventional plastic s...

journal_title：Journal of clinical pathology

authors： Ellis V,Charlett A,Bendall R

更新日期：2004-01-01 00:00:00

abstract：:A patient with chronic granulomatous disease who was being treated with steroids was diagnosed with a soft tissue Scedosporium apiospermum infection. Despite extensive treatment with antifungals progression to involve solid tissue (bone) occurred. Treatment required an HLA matched bone marrow transplant, which led to ...

journal_title：Journal of clinical pathology

authors： Gompels MM,Bethune CA,Jackson G,Spickett GP

更新日期：2002-10-01 00:00:00

abstract：:Infection with Vibrio vulnificus is uncommon in Europe but is associated with necrotising wound infections and life-threatening septicaemia. This case is one of infection most likely to have been acquired from a thermal pool in Turkey without preceding exposure to seawater or shellfish. The report also describes how e...

journal_title：Journal of clinical pathology

authors： Partridge DG,Townsend R,Larkin S,Parsons HK

更新日期：2009-04-01 00:00:00

abstract：:Three selective chromogenic culture media (CHROMagars ESBL, CTX-M and KPC) were evaluated for their ability to support the growth of nine Klebsiella pneumoniae isolates producing OXA-48 carbapenemase in combination with other β-lactamases. CHROMagar ESBL and CHROMagar KPC were the most sensitive media, supporting grow...

journal_title：Journal of clinical pathology

authors： Hornsey M,Phee L,Woodford N,Turton J,Meunier D,Thomas C,Wareham DW

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND/AIMS:In the natural history of gastric cancer, non-invasive neoplasia (NiN) precedes invasive carcinoma. A histological classification of gastric NiN has recently been proposed by a World Health Organisation international panel of experts. Genetic instability is known to be among the molecular pathways invol...

journal_title：Journal of clinical pathology

authors： Rugge M,Bersani G,Bertorelle R,Pennelli G,Russo VM,Farinati F,Bartolini D,Cassaro M,Alvisi V

更新日期：2005-08-01 00:00:00

abstract：:Three hundred and sixty samples of blood from 230 hospital patients were examined and compared with the results of simultaneous blood culture to determine the value of buffy-coat microscopy in detecting bacteraemia. One observer found 86 positive smears, 12 of which were from patients with positive blood cultures and ...

journal_title：Journal of clinical pathology

authors： Coppen MJ,Noble CJ,Aubrey C

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Malignant deciduoid mesothelioma is a rare variant of epithelioid mesothelioma. This tumour generally has poor prognosis, and can be asbestos related. AIM:To identify peculiar genetic changes responsible for critical phases in pathogenesis of malignant deciduoid mesothelioma and their prognostic relevance. ...

journal_title：Journal of clinical pathology

authors： Scattone A,Pennella A,Gentile M,Musti M,Nazzaro P,Buonadonna AL,Marzullo A,Cavone D,Pollice L,Serio G

更新日期：2006-07-01 00:00:00

abstract：:A case of cirrhosis of the liver, associated with false-positive serological tests for syphilis and an antibody active against stored red cells, is presented. Methods used in the identification of the ;stored red cell' antibody are described. ...

journal_title：Journal of clinical pathology

authors： EASTON JA,PRIEST CJ,GILES CM

更新日期：1965-07-01 00:00:00

abstract：AIMS:EGFR tyrosine kinase inhibitors (TKIs) are first-line molecularly targeted therapies in patients with advanced non-small cell lung cancer (NSCLC) who carry sensitising EGFR mutations, due to its superior survival outcomes compared with conventional chemotherapy regimens. In this study, we sought to identify clinic...

journal_title：Journal of clinical pathology

authors： Ng IK,Kumarakulasinghe NB,Syn NL,Soo RA

更新日期：2021-02-01 00:00:00

abstract：:Current techniques for lymphocyte transformation are evaluated and criticised. A simple technique, designed to meet these criticisms, is described in detail, with particular reference to lymphocyte separation and scoring methods. ...

journal_title：Journal of clinical pathology

authors： Pentycross CR

更新日期：1968-03-01 00:00:00

abstract：:The production of heparinase by a wide range of anaerobic bacteria isolated from clinical specimens was investigated. None of the 29 strains of Bacteroides fragilis produced heparinase. Of 62 other Bacteroides tested, only two of four strains of B ovatus, two of three strains of B thetaiotaomicron, and two of four str...

journal_title：Journal of clinical pathology

authors： Riley TV

更新日期：1987-04-01 00:00:00

abstract：:A case of extramedullary myeloblastic transformation of chronic myeloid leukaemia is reported. This was characterised by an unusual clinical and haematological course and showed a unique cytogenetic pattern. ...

journal_title：Journal of clinical pathology

authors： Flanagan NG,Harrison CJ,Harry DS,Ridway JC

更新日期：1985-07-01 00:00:00